Clinical trials: Xenograft
Burns
Use of Nile Tilapia Fish Skin as a Xenograft for Burn Treatment: Phase III Study
The present study is a Phase III Randomized Clinical Trial aiming to evaluate the efficacy of Nile tilapia (Oreochromis niloticus) skin as an occlusive biological dressing in the treatment of superficial partial-thickness burns…
- Trial name
- NCT04202289
- Testing
- Nile Tilapia Fish Skin, Silver Sulfadiazine Cream 1%
- Where
- 2 sites in Brazil
- Volunteers
- 115 people
- Sponsor
- Nucleo De Pesquisa E Desenvolvimento De Medicamentos Da Universidade Federal Do Ceara
Missing Maxillary Anterior Teeth
Poly Tetra Fluro Ethylene vs Native Collagen Membrane for Gbr in Anterior Maxilla
evaluation of amount of bone gained in the anterior maxilla using collagen membranes vs ptfe membrane while using a 1:1 mix of xenograft and autogenous bone
- Trial name
- NCT03839615
- Testing
- guided bone regenerations
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cairo University
Alveolar Ridge Enlargement
Injectable Platelets Rich Fibrin Versus Hyaluronic Acid for Alveolar Ridge Preservation
Thirty-six patients (19 females and 17 males) that required implant placement in esthetic zone participated in this study and were blindly allocated 12 patients per group, all patients had ARP either with I-PRF with xenograft, HA…
- Trial name
- NCT05781529
- Testing
- Alveolar ridge augmentation with injectable platelets rich fibrin, Alveolar ridge augmentation with hyaluronic acid, Alveolar ridge augmentation with xenograft
- Where
- 2 sites in Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Immediate Implant Placement
Effect of Albumin Platelet-Rich Fibrin or Leucocyte- Platelet-Rich Fibrin on Immediate Implant
The objective of this study will be to compare between Immediate Implant grafted with xenograft and Alb-PRF gel versus xenograft with L-PRF.
- Trial name
- NCT06863051
- Testing
- Immediate Implant Placement and Alb-PRF, Immediate Implant Placement and L-PRF
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Triple Negative Breast Cancer
Patient-derived Xenograft (PDX) Modeling of Treatment Response for Triple Negative Breast Cancer
This study will determine if patient-derived tumor xenograft (PDX) mouse models can serve as a reliable model for treatment response for individual patients with triple negative breast cancer.
- Trial name
- NCT02247037
- Testing
- Chemotherapy
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Non Small Cell Lung Cancer
Establishment and Characterization of Patient-Derived Non-Small Cell Lung Cancer Xenografts and Cell Cultures
Xenografts and cell cultures provide sufficient material for analyses at the protein, RNA and DNA level. Patient derived NSCLC xenografts and cell lines are available but none however are Asian in origin.
- Trial name
- NCT01130571
- Testing
- Xenografts and cell cultures
- Where
- Singapore
- Sponsor
- National University Hospital, Singapore
Posterior Maxillary Atrophy, Maxillary Sinus Augmentation
Comparison of Allograft, Xenograft and Combined Grafting in Maxillary Sinus Augmentation
This prospective randomized clinical study evaluates and compares three different grafting approaches (allograft, xenograft, and combined grafting) used in lateral maxillary sinus augmentation prior to dental implant placement.
- Trial name
- SINUS-GRAFT (NCT07407361)
- Testing
- Lateral Maxillary Sinus Augmentation with Allograft, Lateral Maxillary Sinus Augmentation with Xenograft, Lateral Maxillary Sinus Augmentation with Combined Graft
- Where
- Turkey (Türkiye)
- Volunteers
- 37 people
- Sponsor
- Tokat Gaziosmanpasa University
Colorectal Neoplasms, Colorectal Cancer
Personalized Patient Derived Xenograft (pPDX) Modeling to Test Drug Response in Matching Host
By obtaining clinical specimens from participants with triple negative breast cancer (TNBC), colorectal cancer (CRC), high grade serous ovarian cancer (HGSOC), and other select tumor types to establish and profile as freshly…
- Conditions
- Colorectal Neoplasms, Colorectal Cancer, Breast Cancer, Breast Neoplasms
- Trial name
- REFLECT (NCT02732860)
- Testing
- Molecular Profiling & In Vivo drug testing in pPDX and organoid cultures
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- University Health Network, Toronto
Burns, Burn Scar
PORCINE XENOGRAFT OR MICROBIAL CELLULOSE IN THE TREATMENT OF PARTIAL THICKNESS BURNS
The purpose of this study was to compare two wound dressing products for partial thickness burns in adults.
- Conditions
- Burns, Burn Scar, Burn Second Degree
- Trial name
- NCT04412759
- Testing
- microbial cellulose
- Where
- Sweden
- Volunteers
- 26 people
- Sponsor
- University Hospital, Linkoeping
Crestal Bone Loss
Effect of Vitamin D on Crestal Bone Loss Around Immediate Implant After Mandibular Premolars and Molars Extraction
What is the difference between grafting the jumping gap upon using xenograft mixed with topical vitamin D clinically regarding crestal bone level and implant stability, radiographically regarding crestal bone level after implant…
- Trial name
- vitD (NCT07065877)
- Testing
- vit D mixed with xenograft, only xenograft without vit D
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Suez Canal University
Alveolar Cleft
Xenografts With Platelet-rich Fibrin Versus Autogenous Bone in Alveolar Cleft Grafting
this work aims to evaluate xenografts mixed with PRF versus autogenous bone graft in alveolar cleft grafting.
- Trial name
- NCT04693741
- Testing
- secondary alveolar bone graft, Harvesting of the autogenous bone graft, Preparation of PRP
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Assiut University
Class II Furcation Defect
Enamel Matrix Derivative and Xenograft for Mandibular Molar Furcation Defects
This randomized controlled clinical trial aims to compare two regenerative surgical approaches for the treatment of mandibular molar Class II furcation defects in patients with periodontitis.
- Trial name
- NCT07776756
- Testing
- Periodontal Regenerative Surgery With Xenograft and Enamel Matrix Derivative, Periodontal Regenerative Surgery With Xenograft and Collagen Membrane
- Where
- Vietnam
- Volunteers
- 24 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Periodontitis Complex, Xenograft Model
Papillae Tunneling Techniques in the Treatment of Isolated Intrabony Defects
Papillae tunneling techniques (PTT) are a new approach toward regeneration of isolated intrabony defects. Compared to regular papillae preservation techniques, PTT rely on complete preservation of involved interdental papillae…
- Trial name
- PTT (NCT04782921)
- Testing
- Xenogenic bone graft material
- Where
- 2 sites in Slovenia
- Volunteers
- 20 people
- Sponsor
- University of Ljubljana
Guided Bone Regeneration, Bone Augmentation
Lateral GBR Using Two Types of Membrane With a Combination of Allograft-xenograft
Bone width is critical for successful implant placement, as thin bone increases the risk of bone loss. Various augmentation techniques-especially guided bone regeneration (GBR)-are effective in restoring bone volume using grafts…
- Trial name
- NCT07525128
- Testing
- Lateral Guided bone regeneration
- Where
- Lebanon
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Saint-Joseph University
Breast Cancer, Residual
Development of Patient Derived Xenografts (PDX) in Patients With Breast Cancer
Breast cancer patients who undergo neoadjuvant systemic therapy and have residual breast cancer identified at the time of surgery exhibit a high (>50%) risk of future life-threatening recurrences and death.
- Trial name
- NCT04703244
- Testing
- chemotherapy or endocrine therapy for breast cancer
- Where
- United States
- Volunteers
- 999 people
- Sponsor
- Mayo Clinic
Knee Injuries, Anterior Cruciate Ligament (ACL) Reconstruction
OrthoPure™ XT Pilot Clinical Study
To evaluate the clinical safety and obtain preliminary effectiveness data for OrthoPure™ XT device in a small group of US patients at 12 and 24 months.
- Trial name
- NCT03562299
- Testing
- OrthoPure™ XT
- Where
- 3 sites in United States
- Sponsor
- TRX Orthopedics
Periodontal Diseases, Periodontal Bone Loss
Clinical and Radiographic Assessment of Efficacy of Modified Minimally Invasive SurgicalTechnique (M-MIST) Alone and Combined With Enamel Matrix Proteins and Ox-derived Bone Graft in the Treatment of Single Bone Defects Between Teeth.
This study was performed to investigate the adjunctive clinical benefit of the application of enamel matric derivatives and xenograft with the modified minimally invasive surgical technique in the treatment of isolated intrabony…
- Trial name
- NCT07310732
- Testing
- modified minimally invasive surgical technique, modified minimally invasive surgical technique plus emdogain, modified minimally invasive surgical technique plus emdogain and xenograft
- Where
- India
- Volunteers
- 45 people
- Sponsor
- Rungta College of Dental Sciences and Research
Bone Volume, Immediate Implant With Bone Graft
Assessment of Bone Volume Changes in Immediate Implant Placement Using Allograft Versus Xenograft in Mandibular Molars
Twenty recruited patients indicated for immediate implant placement in mandibular molar sites are divided into two groups, with each group containing ten patients.
- Trial name
- NCT06962878
- Testing
- Xenograft, Allograft
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Cairo University