Clinical trials: Xenograft
Implant Dentistry
Efficacy of Xenograft Alone or Mixed With Arginyl-Glycyl-Aspartic Acid (RGD) in Horizontal Ridge Augmentation With Split-crest Technique for Implant Placement
The aim of the present study is to evaluate the efficacy of xenograft alone or xenograft mixed with Arginylglycylaspartic acid (RGD) , in horizontal ridge augmentation with split-crest technique, for implant placement.
- Trial name
- NCT06585852
- Testing
- RGD, Xenograft, Split crest technique
- Where
- Egypt
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Gingival Recession Localized Moderate, Dental Implant
Free Soft Tissue Grafts FSTG) Using Autograft Palatal Donor Tissue vs. Xenograft Collagen Matrix (Zderm™)
Participant in this study are asked to participate because they have teeth or dental implants that were identified as having very little gum tissue and would benefit from gum tissue graft surgery.
- Trial name
- NCT07713199
- Testing
- Zderm
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Severely Atrophic Posterior Maxilla
Two-Stage Transcrestal Sinus Lift With Osseodensification: Allograft vs Autogenous-Xenograft
This study is a prospective, randomized, controlled clinical trial comparing two grafting approaches used during two-stage crestal sinus lifting with osseodensification in patients with severely atrophic posterior maxillae…
- Trial name
- TTSL-OD-AX (NCT07813910)
- Testing
- Osseodensification sinus floor elevation
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Cairo University
Dental Extraction, Wound Heal
Wound Healing Following Tooth Extraction and Ridge Preservation Using DFDBA Alone in Particulate Fiber Form and in Combination With Xenograft
The primary aim of the study is to determine the amount of newly formed vital bone, residual graft material, and "connective tissue/other" 18 to 20 weeks after ridge preservation is performed using DFDBA fibers alone, DFDBA…
- Trial name
- NCT05400213
- Testing
- Vallos (DCP), Vallomix (DCF), Vallos-F (DPX)
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Craniotomy, Duraplasty
Assessment of the Performance of LYoplant® ONlay for Duraplasty
The aim of this Post Market Clinical Follow-up Study is to collect clinical data on the performance of Lyoplant® Onlay. To assess the performance of the product, various safety and efficacy parameters have been selected.
- Conditions
- Craniotomy, Duraplasty, Spinal Surgery
- Trial name
- LYON (NCT02678156)
- Testing
- Lyoplant Onlay
- Where
- 3 sites in Germany
- Volunteers
- 61 people
- Sponsor
- Aesculap AG
Urogenital Neoplasms, Drug Therapy
Potential Therapeutic Response In Urogenital Tumors
Preclinical models of urogenital carcinoma have been emerging as a way to pre-determine drug resistance before therapy is targeted.
- Trial name
- Avatar (NCT03551457)
- Testing
- Biopsy
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- University of Campinas, Brazil
Tooth Extraction, Socket Preservation
Injectable Platelet-rich Fibrin and Advanced Platelet-rich Fibrin With Xenograft on the Socket Preservation of Mandibular Extracted Molars
Different materials and techniques are employed for socket preservation to reduce the alveolar bone resorption in both the horizontal and vertical dimensions as well as the soft tissue collapse after tooth extraction.
- Trial name
- NCT06936358
- Testing
- Control, A-PRF, I-PRF
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- Hams Hamed Abdelrahman
Squamous Cell Carcinoma of the Head and Neck
Patient-derived Xenograft Models of Tumor From Patients With Head and Neck Cancer
The investigators want to have a collection of fresh primary or recurrent tumor tissue for establishment of patients-derived xenografts in order to: generate a biobank of in vivo patient xenografts representing the different…
- Trial name
- UCL-Xenog (NCT02572778)
- Testing
- Local biopsy in the tumor
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Implant Site Reaction
the Peri-implant Tissue Changes Around Implants in the Esthetic Zone Using Demineralized Dentin Graft vs Xenograft
Dentin grafts are categorized into mineralized dentin, partially demineralized dentin matrix (PDDM), and demineralized dentin matrix (DDM).
- Trial name
- NCT06164353
- Testing
- Partially demineralized dentin graft covered with a collagen membrane
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Bone Volume, Immediate Implant With Bone Graft
Assessment of Bone Volume Changes in Immediate Implant Placement Using Allograft Versus Xenograft in Mandibular Molars
Twenty recruited patients indicated for immediate implant placement in mandibular molar sites are divided into two groups, with each group containing ten patients.
- Trial name
- NCT06962878
- Testing
- Xenograft, Allograft
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Cairo University
Burn, Surgery
A Randomized, Controlled Trial of the Effectiveness of Perioperative Antibiotics for Reduction of Burn Wound Bacterial Concentration Following Grafting
The purpose of this study if to evaluate the effectiveness of prophylactic antibiotics given during surgery in reducing the concentration of bacteria in a burn wound after surgery.
- Conditions
- Burn, Surgery, Infection Wound
- Trial name
- NCT04516148
- Testing
- Cefazolin, Clindamycin
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Medstar Health Research Institute
Socket Shield
Comparison of Peri-implant Tissues Using Socket Shield Technique Versus Xenograft
The aim of this study is to clinically and radiographically evaluate the dimensional changes of soft and hard peri-implant tissues around single immediate post-extraction implants in the esthetic zone.
- Trial name
- NCT03684356
- Testing
- socket shield technique, xenograft
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University
Socket Preservation, Alveolar Ridge Preservation
Evaluation of the Effectiveness of the Socket Preservation Technique Using Allogeneic and Xenogeneic Materials
Tooth extraction is among the most common dental treatments. The procedure results in the formation of a bone defect. During the healing phase, the vertical and horizontal diameters of the alveolar ridge decrease, which has a…
- Conditions
- Socket Preservation, Alveolar Ridge Preservation, Xenograft, Allograft
- Trial name
- NCT07565558
- Testing
- Socket preservation with xenograft, Socket preservation with allograft
- Where
- 2 sites in Poland
- Volunteers
- 40 people
- Sponsor
- Medical University of Silesia
Childhood Acute Myeloid Leukemia/Other Myeloid Malignancies
Developing and Treating a Mouse Model of Acute Myeloid Leukemia Using Tissue Samples From Younger Patients With Acute Myeloid Leukemia
These laboratory trial studies the development and treatment of a mouse model for acute myeloid leukemia (AML) using samples from younger patients with AML.
- Trial name
- NCT01576185
- Testing
- laboratory biomarker analysis, quizartinib, sorafenib tosylate
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Children's Oncology Group
Dental Implants
Retrospective Case Series - OSSIX Volumax Collagen Xenograft Scaffolding
This study is designed as a retrospective, single center study. Up to 15 participants who had a transcrestal sinus elevation and implant placement using autogenous bone supporting an OSSIX Volumax collagen xenograft scaffolding…
- Trial name
- NCT06187805
- Testing
- OSSIX Volumax
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Old Orchard Periodontics and Implant Dentistry LTD
Immediate Implant Placement in the Esthetic Zone, NON-RESTORABLE TOOTH IN ESTHETIC ZONE
Hyaluronic Acid Combined With Xenograft Versus Xenograft Alone in Immediate Implant Placement
This randomized controlled clinical trial aims to compare the clinical and radiographic outcomes of immediate implant placement using xenograft combined with hyaluronic acid versus xenograft alone in the esthetic zone.
- Trial name
- NCT07862686
- Testing
- Immediate implant placement, Xenograft, Hyaluronic Acid (0.2%)
- Where
- Egypt
- Volunteers
- 12 people
- Sponsor
- Cairo University
Metastatic Non-Small Cell Lung Carcinoma
Pembrolizumab for Metastatic NSCLC Patients Expressing PD-L1 Who Have Their Own PDX
This is a single center, open-label, single arm study in patients with metastatic non-small cell lung cancer (NSCLC) expressing PD-L1 after failure of platinum-based combination chemotherapy.
- Trial name
- NCT03134456
- Testing
- Pembrolizumab Injection
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Samsung Medical Center
Immediate Implant Placement in Chronic Infected Socket
Efficacy of Mixture of Vancomycin With Xenograft for Immediate Implant Placement in Chronic Infected Socket
Adding local vancomycin to xenografts greatly benefits stability, bone density, and limits marginal bone loss in dental implants in infected socket.
- Trial name
- RCT (NCT07784075)
- Testing
- immediate dental implants Placement in Chronic Infected Socket
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Diabetes Mellitus, Type 1, Hypoglycemia
A Study to Investigate Safety and Effectiveness of Porcine Pancreatic Cells (OPF-310) in Patients With Type 1 Diabetes Mellitus
This study is First In Human study for Encapsulated Porcine Islet Cells for Xenotransplantation (OPF-310). The purpose of this study to assess the safety, tolerability, and efficacy of OPF-310 transplantation and to define the…
- Conditions
- Diabetes Mellitus, Type 1, Hypoglycemia, Islet Cell Transplantation, Type 1 Diabetes
- Trial name
- NCT06575426
- Testing
- OPF-310
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Otsuka Pharmaceutical Factory, Inc.
Implant Site Reaction
Immediate Implant Placement With Immediate Professionalization in Aesthetic Area
Immediate implant placement with immediate professionalization in the maxillary esthetic zone using mixture of allograft and xenograft vs xenografts to augment the jumping gap
- Trial name
- NCT03665025
- Testing
- immediate implant using mixed allograft and xenograft
- Where
- Kuwait
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Cairo University