Clinical trials: Xerophthalmia
Tear Film Insufficiency, Dry Eye
Correlation of Noninvasive Tear Film Function and the Optical Quality in Mild and Moderate Dry Eye
2017 International Dry Eye Workshop (DEWS) defines dry eye as a multifactorial ocular surface disease characterized by tear film instability with disturbed visual function.
- Trial name
- NCT03815539
- Testing
- 0.1% sodium hyaluronate
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Jin Yuan
Dry Eye Syndrome, Tear Film Insufficiency
Tolerability, Safety and Efficacy of Lubricin vs Sodium Hyaluronate Eye Drops in Subjects With Moderate Dry Eye
The objective of the clinical investigation was to evaluate tolerability, safety and efficacy of the tested medical device, eye drop containing Lubricin 150 µg/mL, as compared with a standard sodium hyaluronate 0.13% eye drop…
- Trial name
- NCT02510235
- Testing
- Lubricin, Sodium Hyaluronate
- Where
- 2 sites in Italy
- Volunteers
- 56 people
- Sponsor
- Dompé Farmaceutici S.p.A
Dry Eye
A Prospective Study of the Dry Eye Drink That Evaluates Hydration and Subject's Assessment on Eye Dryness
A study to assess the effect of the Dry Eye Drink on eye dryness
- Trial name
- NCT05949697
- Testing
- Dry Eye Drink
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Bruder Healthcare
Sjogren's Syndrome
Effects of Acupuncture on Sjögren's Syndrome
Sjögren's syndrome (SS) is a multisystemic chronic autoimmune disease characterized by lymphocytic infiltration of the exocrine glands, resulting in salivary and lacrimal glands hypofunction, with symptoms of dry eyes and mouth.
- Trial name
- NCT04056221
- Testing
- Acupuncture
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Ana Carolina Fragoso Motta, DDS, PhD
Amblyopia, Myopia
Performance of a Photoscreener for Vision Screening in a Haitian Pediatric Population
Screening of haitian children between the ages of 3 and 6 years old for amblyogenic risk factors with the use of the Spot photoscreener. The photoscreener results will be compared to the complete ophthalmologic evaluation.
- Conditions
- Amblyopia, Myopia, Hyperopia, Astigmatism
- Trial name
- POPH (NCT02655432)
- Testing
- Spot photoscreener, Ophthalmologic evaluation, Cyclopleged refraction
- Where
- 3 sites in Haiti
- Volunteers
- healthy volunteers welcome
- Sponsor
- Université de Montréal
Uveitis, Conjunctivitis
Ocular Manifestations in Rheumatic Diseases
This is a search strategy for determining the prevalence of ocular complications in inflammatory rheumatic diseases for the purposes of a meta analysis.
- Conditions
- Uveitis, Conjunctivitis, Keratoconjunctivitis Sicca, Xerophthalmia
- Trial name
- NCT03753893
- Testing
- No intervention used
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Sjogren's Syndrome
Safety of Tofacitinib, an Oral Janus Kinase Inhibitor, in Primary Sjogren Disease
Background: Sjogren disease is an autoimmune disease - that is, a disease that causes the body's immune system to attack its own organs and tissues. Sjogren disease can affect the kidneys, lungs, or other organs.
- Trial name
- NCT07281456
- Testing
- Tofacitinib
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Cataract
Corneal Protect Used During Cataract Surgery
This randomized controlled subject- and examiner-masked study comprised patients scheduled for cataract surgery.The patients will be randomly assigned to receive either balanced salt solution（BSS）or hydroxypropyl…
- Trial name
- CPUDCS (NCT02363530)
- Testing
- Hydroxypropyl ethylcellulose (HPMC) 2% gel, BSS
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Xerophthalmia
Clinical Study for the Evaluation of Safety and Tolerability of NCP112 Eye Drops
The objective is to evaluate the safety, local tolerability, and pharmacokinetics of NCP112 eye drops through single and multiple dose-escalation ocular administrations in healthy adults.
- Trial name
- NCT06263998
- Testing
- NCP112
- Where
- South Korea
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Huons Co., Ltd.
Xerophthalmia, Blepharitis
Trial to Compare the Efficacy of Systane Ultra and Refresh Drop in the Treatment of Dry Eye in Asian Eyes
Systane Ultra is at least as efficacious and safe as Refresh Tears in Asian people with Dry Eyes
- Trial name
- NCT00796926
- Testing
- Systane Ultra eyedrops, Refresh eye drops
- Where
- Singapore
- Volunteers
- 30 people
- Sponsor
- Louis Tong