Clinical trials: Young
Leukemia, Lymphoma
BL22 Immunotoxin In Treating Young Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia or Non-Hodgkin's Lymphoma
RATIONALE: BL22 immunotoxin can locate tumor cells and kill them without harming normal cells. BL22 immunotoxin may be effective in treating relapsed or refractory acute lymphoblastic leukemia and non-Hodgkin's lymphoma.
- Trial name
- NCT00077493
- Testing
- BL22 immunotoxin, antibody-drug conjugate therapy, immunotoxin therapy
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- MedImmune LLC
Anesthesia
Pharmacokinetic Study of Intravenous Lidocaine in Young and Elderly Patients
Aging is accompanied by a gradual alteration in the functional reserve of several organs and a change in body composition that can affect the pharmacokinetics, response, and safety profile of medications.
- Trial name
- ElderLIDO_1 (NCT06795100)
- Testing
- Pre-inclusion, Inclusion, Lidocaine
- Where
- 2 sites in France
- Volunteers
- 67 people
- Sponsor
- Rennes University Hospital
Dental Plaque, Gingival Diseases
Effectiveness of Dental Health Education Methods on Oral Hygiene, Oral Health Care Self-Efficacy and Self-Esteem of Young Orphans
Background: Orphan children are at higher risk of developing oral diseases, compared to non-orphans. They also face various emotional, social, and psychological distresses which affect their general as well as oral health.
- Conditions
- Dental Plaque, Gingival Diseases, Oral Health, Self Efficacy
- Trial name
- NCT07771634
- Testing
- Conventional dental health education, Game based dental health education, Peer-group based dental health education
- Where
- Egypt
- Volunteers
- 264 people
- Sponsor
- Alexandria University
Forward Head Posture
McKenzie Retraction and Bruegger's Exercises Effects on Forward Head Posture
The aim of the study is to compare effects of McKenzie Retraction exercises and Bruegger's exercise on neck pain, ROM, craniovertebral angle and functional performance on forward head posture among young adults.
- Trial name
- NCT06086834
- Testing
- McKenzie Retraction Exercises, Bruegger's Exercise
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Riphah International University
Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm
A Culturally-Tailored Mobile Health and Social Media Physical Activity Intervention for Improving Physical Activity in Hispanic or Latino/Latina Adolescent and Young Adult Childhood Cancer Survivors, Walking Juntos Study
This clinical trial tests the impact of a culturally-tailored home-based physical activity program on physical fitness in Hispanic or Latino/Latina adolescent and young adult (AYA) childhood cancer survivors.
- Trial name
- NCT06410209
- Testing
- Discussion, Goal Setting, Interview
- Where
- 77 sites in United States, Puerto Rico
- Volunteers
- 190 people
- Sponsor
- Children's Oncology Group
Carious Teeth
Evaluation of Partial Versus Complete Pulpotomy in Carious Immature Molars Permanent Teeth Using Bioceramic Material
One of our major concerns and daily challenges is the management of carious immature permanent teeth, also known as young permanent teeth while preserving the vitality of the dental.
- Trial name
- NCT06101550
- Testing
- partial pulpotomy, Complete pulpotomy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Depression Disorder, Anxiety
Impact of Nut Consumption on Mental Health in Young Adults
Nuts have a high nutrient density, and numerous studies have reported their cardiometabolic benefits. Although observational studies in adults have indicated a potential link between nut consumption and improved mental health…
- Conditions
- Depression Disorder, Anxiety, Mental Health, Stress
- Trial name
- NUTS4BRAIN-RCT (NCT07292610)
- Testing
- mixed nuts. Group A, mixed nuts. Group B, control group
- Where
- Spain
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- University of Castilla-La Mancha
Hypertension
Targeting Microvascular Dysfunction in Young Hypertensive Patients
Cholesterol and blood pressure lowering tablets have been shown to be of benefit in patients with established high blood pressure.
- Trial name
- NCT01047423
- Testing
- Simvastatin
- Where
- United Kingdom
- Sponsor
- Queen's University, Belfast
Iodine Bioavailability
Bioavailability of Iodine for Natural Kelp and Iodized Salt in Young Adults
Iodine is an essential micronutrient for the production of thyroid hormones and its deficiecny remains a global problem impairing health.
- Trial name
- NCT04933279
- Testing
- iodine-containg spareribs soup, intrinsic iodine in natural kelp
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Liu Xiao Bing
Autism
To Share or Not To Share: Navigating Disclosure and Stigma Among Family Caregivers of Autistic Young Adults_Group Intervention
This study is a caregiver support program for family caregivers of autistic young adults (ages 18 to 26) as their family members navigate young adulthood.
- Trial name
- NCT07856927
- Testing
- Group Intervention
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Wisconsin, Madison
Anemia
Using Iron Supplementation to Decrease Iron Deficiency Anemia in Infants and Young Children in India
The purpose of this study is to determine the smallest dose of Sprinkles, a single-serving package of iron and other micronutrients, to treat infants with iron deficiency anemia in India.
- Trial name
- NCT00213161
- Testing
- iron supplement, iron drops
- Where
- India
- Volunteers
- 425 people
- Sponsor
- The Hospital for Sick Children
Alzheimer's Disease
A Study to Evaluate the Pharmacokinetics and Safety of BEY2153 in Healthy Participants
This is a first in human Phase 1 study to evaluate the safety, tolerability and pharmacokinetics with healthy young and elderly adult male volunteers after receiving single and multiple ascending dose of BEY2153.
- Trial name
- NCT04476303
- Testing
- BEY2153
- Where
- South Korea
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- BeyondBio Inc.
Myocardial Infarction
Prevalence and Long-term Impact of Non-atherosclerotic CAD
Despite a relatively high prevalence of non-atherosclerotic coronary artery disease (NACAD) among young women, the majority of these abnormalities were misdiagnosed in this population, and thus treatments were not targeted…
- Trial name
- PRYME (NCT01479140)
- Where
- Canada
- Volunteers
- 160 people
- Sponsor
- Cardiology Research UBC
Female Hormone Profile
Acute Vitamin D Supplementation on Testosterone in Females
Participation will take place over two visits to the Clinical Exercise Research Center (CERC) at the University of Southern California Health Sciences Campus.
- Trial name
- NCT06610968
- Testing
- Vitamin D (Cholecalciferol )
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Fatigue
Fatigue Intervention Co-design Study in Teenagers and Young Adults With Cancer
Fatigue is one of the most common and distressing symptoms in teenage and young adult cancer patients. Despite this, there has been virtually no research evaluating treatment for cancer-related fatigue in this young patient…
- Trial name
- NCT02719561
- Testing
- Fatigue Intervention
- Volunteers
- 20 people
- Sponsor
- Anna Spathis
Cancer
Wilderness Program for Adolescent and Young Adult Cancer Survivors
Young cancer survivors are at higher risk of cancer reoccurrence, frailty, suicidal ideation, sedentary behaviour, reduced quality of life, and reduced overall life expectancy, compared to their siblings or healthy young persons.
- Trial name
- WAYA (NCT04761042)
- Testing
- WAYA-Wilderness, WAYA-Holiday
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Mid Sweden University
Arthritis, Juvenile
Exercise and Body Composition in Juvenile Idiopathic Arthritis
This research is being done to see if resistance exercise (RE) is safe and has a positive effect on children and young adults with juvenile idiopathic arthritis (JIA).
- Trial name
- Joint Fitness (NCT02479373)
- Testing
- Ren-Ex Machine, Dual-Emission X-ray Absorptiometry (DEXA) scan, Biodex dynamometer
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Johns Hopkins University
Cognition, Mood
Investigation of the Acute Effects of Nepalese Pepper Extract (Zanthoxylum Armatum DC) on Cognitive Function, Mood and Gaming Performance in Young, Healthy, Competitive Gamers
The goal of this clinical trial is to learn if a Nepalese Pepper Extract (Zanthoxlum Armatum, ZA) supplement can improve cognitive performance and mental abilities in competitive gamers aged 16 to 34.
- Conditions
- Cognition, Mood, Gaming Performance, Fatigue
- Trial name
- NCT07047105
- Testing
- Nepalese Pepper (Zanthoxylum Armatum) extract 150mg, Nepalese Pepper (Zanthoxylum Armatum) extract 300mg, Caffeine 75mg
- Where
- United Kingdom
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Northumbria University
HIV-1-infection
ANCHORS Study: UH2 Project
According to the National HIV/AIDS Strategy, men who have sex with men (MSM), young adults, Black and Latino men and people in the Southern U.S.
- Trial name
- ANCHORS (NCT03360422)
- Testing
- Survey, Focus Group, Usability study
- Where
- United States
- Volunteers
- 673 people, healthy volunteers welcome
- Sponsor
- University of Florida
Depression, Anxiety
Digital Mental Health Service for Non-Treatment Seeking Young Adults
This is a feasibility trial of a personalized 8-week text messaging intervention aimed at young adults (ages 18-25) with depression and anxiety who are not interested in -- or experience barriers to -- receiving traditional…
- Conditions
- Depression, Anxiety, Suicidal Ideation
- Trial name
- NCT04948268
- Testing
- Adaptive messaging intervention, Non-personalized messaging intervention, Coaching
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Northwestern University