Clinical trials: Young Adult
Individuality, Healthy
Vaccination Responses in Young and Older Adults
To follow longitudinally healthy and immune-compromised responses to pneumococcal vaccination, in 60+ individuals towards the development of personalized medicine implementation (minimum enrollments in 2 age categories: young…
- Conditions
- Individuality, Healthy, Asthma, Immune System and Related Disorders
- Trial name
- NCT02654704
- Testing
- Pneumococcal Vaccination
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Michigan State University
Healthy
Pilot Study for the Effects of Transcranial Magnetic Stimulation on the Brain Using an Electronic Medical Device
This study is a randomized, double-blind, and sham-controlled trial to examine the effects of transcranial magnetic stimulation on the brain of health individuals.
- Trial name
- NCT02932085
- Testing
- Neurostar TMS Therapy System, NeuroStar XPLOR System
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ewha Womans University Mokdong Hospital
Gait Variability; Elders; Fall; Re-education
Effect of Observation Plus Imagination of Gait on Stride Variability in Young and Older Adults
The aim of study is to examine the combined effect of observation and imagination of gait on stride time variability of stride time among in healthy young and older adults.
- Trial name
- OBI (NCT02120144)
- Testing
- Observation & imagination, Reading
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Atherosclerotic Plaque, Diabetes Mellitus, Type 2
Pakistan Study of Premature Coronary Atherosclerosis in Young Adults
Coronary heart disease (CHD) is a major cause of morbidity, disability, mortality, and health expenditures worldwide. A wealth of studies has demonstrated that people of South Asian ancestry have a higher risk of CHD and…
- Conditions
- Atherosclerotic Plaque, Diabetes Mellitus, Type 2, Hypertension, Stroke
- Trial name
- PAKSEHAT (NCT05156736)
- Where
- Pakistan
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Tabba Heart Institute
Hemophilia A
Once-A-Day Prophylaxis for Youth and Young Adults With Severe Hemophilia A
The primary objective of this study is to test the feasibility of a large-scale clinical trial of once-daily prophylaxis. The secondary objectives are to collect clinical efficacy outcomes so that we can better plan a large-scale…
- Trial name
- NCT00717626
- Testing
- Kogenate FS, Advate, or Humate-P, Recombinate, Helixate FS
- Where
- 3 sites in Canada
- Volunteers
- 14 people
- Sponsor
- The Hospital for Sick Children
Fatigue; Muscle, Heart, Fasting
Effects of Fasting-Mimicking Diet on Central and Peripheral Components of Fatigue, Muscular Resistance
The aim of the study is to test a Fasting Mimicking Diet (FMD) for its efficacy on improving muscular resistance and endurance. The investigators will perform a randomized clinical trial to test the efficacy of the FMD on…
- Conditions
- Fatigue; Muscle, Heart, Fasting, Diet, Healthy, Fatigue, Mental
- Trial name
- FMD_Exercise (NCT04476615)
- Testing
- Fasting-Mimicking Diet (ProLon®)
- Where
- Italy
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universita di Verona
Cancer
Patient Navigation in the Adolescent and Young Adult (AYA) Cancer Population
The purpose of this study is to develop and test a model of patient navigation that investigators hope will address the unique needs of adolescent and young adult (AYA) cancer patients and their families by minimizing barriers in…
- Trial name
- NCT03176576
- Testing
- Patient Navigator (PN), Baseline Questionnaire, Follow-up Questionnaire
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Healthy
fMRI Study of the Cerebal Bases of the Spatialization Process in Working Memory
The present neuroimaging study investigates cerebral and behavioral markers of spatialization. Spatialization in memory corresponds to a mental representation of successive items from left to right in Westerners.
- Trial name
- IRMF-SPAT (NCT05764863)
- Testing
- fMRI
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Major Depression
Study of Brain Response to Emotional Pictures Using a Magnetic Resonance Imaging (fMRI) While on Escitalopram
The purpose of this study is to find out what parts of the brain have increased or decreased activity when people are depressed and how antidepressant medicine changes this activity in depressed patients.
- Trial name
- NCT00707863
- Testing
- Escitalopram
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Indiana University
Autism
Safety of L1-79 in Adolescent and Adult Males With Autism
This is a five-arm designed to assess the safety of L1-79 that incorporates 15 prospectively randomized, placebo controlled patients and 5 open label patients at either 100 tid (three times daily) or 200 tid dosing for 28 days.
- Trial name
- NCT02947048
- Testing
- L1-79
- Where
- 2 sites in United States
- Volunteers
- 42 people
- Sponsor
- Yamo Pharmaceuticals LLC
Anorexia Nervosa
Study of Psilocybin for Anorexia in Young Adults
This is a single site trial of psilocybin therapy for the treatment of refractory Anorexia Nervosa in young adults. The psilocybin therapy will include three preparatory sessions, psilocybin dosing session one (20mg), two…
- Trial name
- SPANYA (NCT06399263)
- Testing
- Psilocybin, Preparation and Integration Sessions
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Marissa Raymond-Flesch, MD, MPH
Hepatic Encephalopathy
ETOS: Minimal Hepatic Encephalopathy in Childhood and Young Adult: epidemiOlogical Study and Pilot Interventional Study
The aim of the study is: Epidemiological/observational: investigating the presence of neuropsychological and electrophysiological alterations, suggesting a condition of minimal hepatic encephalopathy(and its behavioral…
- Trial name
- ETOS (NCT01798329)
- Testing
- probiotic VSL#3
- Where
- 2 sites in Italy
- Volunteers
- 50 people
- Sponsor
- A.O. Ospedale Papa Giovanni XXIII
Leukemia, Myelodysplastic Syndromes
Genomically Profiling, Collecting, Archiving and Distributing Hematologic Malignancy Specimens
This research study is a genomic profiling and repository study for children and young adults who have leukemia, myelodysplastic syndrome (MDS) or myeloproliferative syndrome (MPS).
- Conditions
- Leukemia, Myelodysplastic Syndromes, Myeloproliferative Syndrome
- Trial name
- NCT04968834
- Testing
- Genomic profiling
- Where
- 8 sites in United States
- Volunteers
- 300 people
- Sponsor
- Dana-Farber Cancer Institute
Cardiovascular System, Respiratory System
Acute Health Effects of Traffic-Related Air Pollution Exposure
This study aims to assess the effects of acute exposure to traffic-related air pollution and the underlying mechanisms.
- Trial name
- NCT04153539
- Testing
- Walking along a busy road, Walking in a traffic-free park
- Where
- China
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Fudan University
Acute Lymphoblastic Leukemia, Hodgkin Lymphoma
Evaluating the Impact of Social and Genetic Factors on Outcomes in Adolescent and Young Adult Cancer Survivors
This study examines the impact of social and genetic factors on outcomes in adolescent and young adult (AYA) cancer survivors of Hodgkin or non-Hodgkin lymphoma or leukemia.
- Conditions
- Acute Lymphoblastic Leukemia, Hodgkin Lymphoma, Non-Hodgkin Lymphoma
- Trial name
- NCT06002828
- Testing
- Non-Interventional Study
- Where
- 507 sites in United States
- Volunteers
- 2,000 people
- Sponsor
- ECOG-ACRIN Cancer Research Group
Neuroblastoma
Activity Study of Bevacizumab With Temozolomide ± Irinotecan for Neuroblastoma in Children
The purpose of this study is to investigate whether Bevacizumab (an anti-VEGF monoclonal antibody) added to a backbone chemotherapy regimen (Temozolomide, Irinotecan-Temozolomide or Topotecan-Temozolomide) demonstrates activity…
- Trial name
- BEACON (NCT02308527)
- Testing
- Bevacizumab, Temozolomide, Irinotecan
- Where
- 10 sites in Austria, Belgium and 8 more
- Volunteers
- 225 people
- Sponsor
- University of Birmingham
Recurrent Malignant Solid Neoplasm, Recurrent Osteosarcoma
Pepinemab in Treating Younger Patients With Recurrent, Relapsed, or Refractory Solid Tumors
This phase I/II trial studies the side effects and best dose of pepinemab and to see how well it works in treating younger patients with solid tumors that have come back after treatment, or do not respond to treatment.
- Conditions
- Recurrent Malignant Solid Neoplasm, Recurrent Osteosarcoma, Refractory Malignant Solid Neoplasm, Refractory Osteosarcoma
- Trial name
- NCT03320330
- Testing
- Laboratory Biomarker Analysis, Pepinemab, Pharmacological Study
- Where
- 24 sites in United States
- Volunteers
- 26 people
- Sponsor
- Children's Oncology Group
Pediatric Brain Tumor
Survivors Journey+
The main goal of this pilot randomized controlled trial is to learn if an online program called "Survivors Journey" (SJ+) can help teens and young adults, ages 15-25, who are Pediatric Brain Tumor Survivors (PBTS), and their…
- Trial name
- SJ (NCT07321353)
- Testing
- Survivor's Journey+
- Where
- 2 sites in United States
- Volunteers
- 72 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Osteogenesis Imperfecta (OI)
Open-label Extension of Study 20130173 of Denosumab in Children and Young Adults With Osteogenesis Imperfecta
To evaluate long-term safety of denosumab in children/young adults with pediatric osteogenesis imperfecta (OI) who completed the prior study 20130173 (NCT02352753).
- Trial name
- NCT03638128
- Testing
- Denosumab, Alternative osteoporosis medications
- Where
- 22 sites in United States, Australia and 10 more
- Volunteers
- 75 people
- Sponsor
- Amgen
Sleep Restriction
Impact of a Sleep Debt in Middle-Aged and Older Adults
This project has 6 aims. 1. To examine the impact of recurrent partial sleep loss in young, middle-aged and older men and women. Sleep will be restricted to 4 hours. 2.
- Trial name
- PPG (NCT00817700)
- Testing
- Sleep restriction
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Chicago