Clinical trials: Young Adults
Psychosis, Sleep
Melatonin Effects on Sleep and Circadian Rhythm in Youth and Young Adults With At-risk Symptoms
Randomized control trial assessing supplemental melatonin for youth with at-risk or psychotic symptoms.
- Trial name
- NCT03826563
- Testing
- oral melatonin tablets (NatureMade brand)
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Children's Hospital of Philadelphia
Type 1 Diabetes (T1D), Diabetes Secondary to Pancreatitis
Digital Mindfulness for Young Adults With Type 1 Diabetes
The purpose of this research study is to test a mindfulness app called Calm Health among young adults with type 1 diabetes or other absolute insulin deficiency diabetes.
- Trial name
- NCT07062887
- Testing
- Mindfulness app
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Yale University
Non-suicidal Self-injury
Treatment for Non-Suicidal Self-Injury in Young Adults
The purpose of this study is to investigate an intervention specifically for non-suicidal self-injury (NSSI) in young adults. The goal of this 9-session outpatient intervention is to reduce the frequency and severity of NSSI.
- Trial name
- T-SIB (NCT01018433)
- Testing
- T-SIB, Treatment as usual
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Fordham University
Glioma, Malignant, Embryonal Tumor
Integrated Analysis of Therapy Response and Resistence in Embryonal Tumors and Gliomas
The treatment of adolescents and young adults (AYA, 15 to 39 years) with malignant intra-axial CNS parenchymal tumors such as IDH-mutated gliomas, medulloblastomas and ependymomas is still not curative in all cases.
- Conditions
- Glioma, Malignant, Embryonal Tumor, Medulloblastoma, Ependymoma
- Trial name
- BZKF-AYA (NCT06323408)
- Testing
- Tissue, blood, cerebrospinal-spinal fluid
- Volunteers
- 72 people
- Sponsor
- University Hospital Regensburg
Fatigue; Muscle, Heart, Fasting
Effects of Fasting-Mimicking Diet on Central and Peripheral Components of Fatigue, Muscular Resistance
The aim of the study is to test a Fasting Mimicking Diet (FMD) for its efficacy on improving muscular resistance and endurance. The investigators will perform a randomized clinical trial to test the efficacy of the FMD on…
- Conditions
- Fatigue; Muscle, Heart, Fasting, Diet, Healthy, Fatigue, Mental
- Trial name
- FMD_Exercise (NCT04476615)
- Testing
- Fasting-Mimicking Diet (ProLon®)
- Where
- Italy
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universita di Verona
Mental Health Issue, Adolescent Behavior
Effectiveness of Promoting the Role of General Practitioners in a Mental Health Care System Integrated With Primary Care in Adolescence, According to the World Health Organization Definition
MG-integr-ADO aims to create and evaluate in France, a system of integrated mental health care in primary care for adolescents with mental illness.
- Trial name
- MGIntegrADO (NCT07186335)
- Testing
- self-questionnaire
- Volunteers
- 1,400 people
- Sponsor
- Fondation Santé des Étudiants de France
Nicotine Addiction, E-Cig Use
Quit Smoking Study for People Who Use E-Cigarettes
The overarching aim of this proposed randomized controlled trial (RCT) is to test nicotine replacement therapy (NRT) with text message support for two smoking cessation approaches among young adult dual users of combustible…
- Conditions
- Nicotine Addiction, E-Cig Use, Quitting Smoking
- Trial name
- NCT04946825
- Testing
- Nicotine replacement therapy patch, Nicotine replacement therapy lozenge, Quit electronic cigarettes
- Where
- United States
- Volunteers
- 396 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Young Adult, Plantar Pressure Distrubution
Plantar Pressure and Pain in Young Adults
The musculoskeletal system represents a holistic movement organization emerging from the integrated function of the central nervous system, musculoskeletal structures, and joint complexes.
- Conditions
- Young Adult, Plantar Pressure Distrubution, Pain
- Trial name
- NCT07568925
- Testing
- Plantar Pressure Measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Fenerbahce University
Dietary Supplementation, Healthy Vollunteer
Effect of β-alanine Supplementation and Training on Ergogenic Measures and Plasma Metabolites in Untrained Young Adults
This study enrolled untrained young adults to evaluate the effects of β-alanine supplementation combined with a structured exercise training program.
- Trial name
- NCT07404540
- Testing
- β-Alanine
- Where
- Hungary
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Pecs
Acute Lymphoblastic Leukemia, in Relapse, Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Recurrent
HEM-iSMART-A: Decitabine / Venetoclax and Navitoclax in Pediatric Patients With Relapsed or Refractory Hematological Malignancies
HEM-iSMART is a master protocol which investigates multiple investigational medicinal products in children, adolescents and young adults (AYA) with relapsed/refractory (R/R) ALL and LBL.
- Conditions
- Acute Lymphoblastic Leukemia, in Relapse, Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Recurrent, Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Recurrent, Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Refractory
- Trial name
- HEM-iSMART A (NCT05740449)
- Testing
- Decitabine, Venetoclax, Navitoclax
- Where
- Netherlands
- Sponsor
- Princess Maxima Center for Pediatric Oncology
Protein Metabolism
Amino Acid Oxidation of Whole-Food Protein: a Dose-Response Crossover Trial in Young Adults
The purpose of this study is to assess the amino acid oxidation dose-response relationship of ingested whole-food protein in healthy adults.
- Trial name
- BURGER (NCT07547176)
- Testing
- Food proteins
- Where
- Netherlands
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
B-NHL, B-Non Hodgkin Lymphoma
CD19/CD22 Bicistronic Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory B Cell Malignancies
Background: Acute lymphoblastic leukemia (ALL) is the most common cancer in children. About 90% of children and young adults who are treated for ALL can now be cured.
- Conditions
- B-NHL, B-Non Hodgkin Lymphoma, Acute Lymphocytic Leukemia, Acute Lymphoblastic Leukemia
- Trial name
- NCT05442515
- Testing
- CD19/CD22-CAR-transduced T cells, cyclophosphamide, fludarabine
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- National Cancer Institute (NCI)
Healthy Participants, Healthy Young Adults
Foam Rolling, Blood Pressure and Range of Motion
Foam rolling (FR) is a technique involving the application of external pressure to muscles and connective tissues using different devices (e.g.
- Trial name
- NCT07433543
- Testing
- Cervical foam rolling
- Where
- Italy
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Palermo
Avian Influenza, Influenza Immunisation
H5N1 With or Without Topical Aldara in Healthy Adults
Phase I randomized, double-blind, placebo-controlled trial in 50 males and non-pregnant females, 18 to 49 years old, who are in good health and meet all eligibility criteria.
- Trial name
- NCT03472976
- Testing
- Aqueous Cream B.P., Imiquimod, Influenza Virus Vaccine, Monovalent A/H5N1 A/Vietnam/1203/04
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Acellular Pertussis, Tetanus
Immunogenicity & Reactogenicity of Boostrix 10 Years After Previous Booster Vaccination.
The purpose of this study is to assess the efficacy and safety of repeating dTpa booster in adults 10 years after previous booster vaccination with dTpa in a prior clinical study.
- Conditions
- Acellular Pertussis, Tetanus, Diphtheria
- Trial name
- NCT00610168
- Testing
- Boostrix TM
- Where
- Finland
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Cancer, Young Adults
Harnessing Generativity Among Young Adult Cancer Survivors
Short, online interventions designed to enhance well-being may be particularly amenable for use with adolescent and young adult (AYA) cancer survivors (age 15-39 at diagnosis), an understudied group in the cancer community.
- Trial name
- NCT04272346
- Testing
- Writing for others, Processing + writing for others, Facts-only writing
- Where
- United States
- Volunteers
- 204 people
- Sponsor
- University of California, Los Angeles
Attention Deficit Hyperactivity Disorder
Expectation of Driving Performance in Young Adults With ADHD Assessed by Driving Simulator and Seat Pressure Mapping
Adolescents suffering of ADHD may have impaired driving performance. The investigators would like to check the differences in driving performance in young adults(aged: 15-18 years) with ADHD by driving simulator and seat pressure…
- Trial name
- NCT01179386
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Fragile X Syndrome, Fragile X Syndrome (FXS)
Clinical Study of Cannabidiol in Children, Adolescents, and Young Adults With Fragile X Syndrome
This is a randomized, double-blind, placebo-controlled, multiple-center study, to assess the efficacy and safety of cannabidiol administered as ZYN002 for the treatment of children, adolescent, and young adult patients with…
- Trial name
- RECONNECT (NCT04977986)
- Testing
- ZYN002
- Where
- 27 sites in United States, Australia and 3 more
- Volunteers
- 257 people
- Sponsor
- Harmony Biosciences Management, Inc.
Overweight and Obese, Young Adult
Effects of Kettlebell Swing Training Combined With Breathing Exercises on Respiratory Muscle Strength and Pulmonary Function in Overweight and Obese Young Adults
Overweight and obesity are associated with impaired breathing mechanics, including reduced chest wall and diaphragmatic movement, decreased respiratory muscle strength and endurance, and inefficient breathing patterns.
- Trial name
- Kettlebell (NCT07802080)
- Testing
- Kettlebell swing training, Control
- Where
- Thailand
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Phayao
Mental Health Wellness 1, Health Care Utilization
Black Economic Equity Movement
The primary goal is to understand the potential impacts of Guaranteed Income (GI) on Black youth and young adults' financial, emotional, and physical well-being.
- Conditions
- Mental Health Wellness 1, Health Care Utilization, Financial Hardship, Education, Professional
- Trial name
- BEEM (NCT05609188)
- Testing
- Guaranteed Income, Peer learning circles, Financial coaching
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
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