Clinical trials: Young Adults
Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia
Ruxolitinib With Tacrolimus and Methotrexate for the Prevention of Graft Versus Host Disease in Pediatric and Young Adult Patients Undergoing Allogeneic Hematopoietic Cell Transplant for Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or Myelodysplastic Syndrome
This phase II trial tests how well ruxolitinib with tacrolimus and methotrexate work to prevent the development of graft versus host disease in pediatric and young adult patients undergoing allogeneic hematopoietic cell…
- Conditions
- Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Myelodysplastic Syndrome
- Trial name
- NCT06128070
- Testing
- Biospecimen Collection, Chest Computed Tomography, Echocardiography
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- City of Hope Medical Center
Depression
Addressing Mental Health in African American Job Training Adolescents and Young Adults
This project's focus is twofold-to change the culture of an employment training program for adolescents and young adults (Youth Opportunities, or "YO") to more fully address the many mental health issues faced by its participants…
- Trial name
- NCT00979524
- Testing
- Comprehensive Mental Health Services and Supports
- Where
- United States
- Volunteers
- 782 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Healthy
Effect of an Alpha-linolenic Acid-rich Supplement on Ketogenesis and Plasma Fatty Acids
Background: As the main alternative fuel to glucose for the brain, increased plasma ketones could potentially help compensate for brain glucose hypometabolism occurring during aging.
- Trial name
- NCT02410161
- Testing
- alpha-linolenic acid-rich supplement
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
E-cigarette Use
An Online Intervention to Reduce E-cigarette Use and Susceptibility to Smoking in Young Adults
The goal of this intervention development and pilot clinical trial is to determine whether receiving the brief online intervention results in greater reductions in past 7-day e-cigarette use frequency and smoking susceptibility…
- Trial name
- NCT06129123
- Testing
- Live Free From E-cigarettes
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Cancer Patients, Young Adult
Bright IDEAS - Young Adults Problem-Solving Skills Training
The purpose of this project is to evaluate efficacy of Bright IDEAS, an evidence-based problem-solving skills training (PSST) program, as a supportive care intervention for young adult (YA) cancer patients compared with enhanced…
- Conditions
- Cancer Patients, Young Adult, Supportive Care
- Trial name
- NCT04585269
- Testing
- Bright IDEAS-YA
- Where
- 3 sites in United States
- Volunteers
- 344 people
- Sponsor
- Rutgers, The State University of New Jersey
Mild Dehydration
The Effect of Acute Mild Dehydration on Blood Pressure Control
The goal of this project is determine how acute mild dehydration impacts blood pressure control at rest and during static exercise.
- Trial name
- NCT03560869
- Testing
- Normal hydration, Dehydration
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Delaware
Cannabis Use Disorder
A Study of Cannabidiol in Young Adult Cannabis Users
The investigators will study the harm-reducing effect of hemp-derived CBD in non-treatment-seeking emerging adults who use cannabis regularly.
- Trial name
- NCT06569394
- Testing
- Broad Spectrum Cannabidiol (bsCBD) 400 mg
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Colorado, Denver
Neck Pain
Risk Factors and Risk Profiles for Persistent Neck Pain in Young Adults: Results From the HUNT Study
Neck pain is one of the most prevalent musculoskeletal disorder in Norway among older adolescents and young adults. Despite this, little research exist on risk factors for neck pain in the transitional life phase from adolescence…
- Trial name
- NCT04201366
- Testing
- No intervention
- Where
- Norway
- Volunteers
- 8,562 people, healthy volunteers welcome
- Sponsor
- Oslo Metropolitan University
Healthy
Feasibility and Acceptability of Mindful Self-Compassion Among Transgender and Nonbinary Young Adults
The goal of this single-arm feasibility study is to evaluate the feasibility and acceptability of an 8-week mindful self-compassion intervention and associated data-collection plan among transgender and nonbinary young adults.
- Trial name
- NCT06409975
- Testing
- Mindful Self-Compassion (MSC)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Rhode Island
Survivorship, Cancer
Financial Navigation Study Among Young Adult Blood Cancer Survivors
Young adult cancer survivors (18-39y) are at increased risk of financial distress. This study seeks to better understand the financial challenges experienced by these individuals via quantitative serial assessments, study-based…
- Conditions
- Survivorship, Cancer, Financial Stress
- Trial name
- NCT05620979
- Testing
- Providing financial navigation via active navigation, ad hoc navigation or no study-based navigation.
- Where
- 5 sites in United States
- Volunteers
- 130 people
- Sponsor
- Tufts Medical Center
COPD, COPD-like
Breathing Performance of Healthy Young Adult
The study will recruit subject of healthy adult, COPD-like patient and patient with COPD to investigate the difference of respiratory performance.
- Trial name
- NCT04857541
- Where
- Taiwan
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Healthy
Effectiveness of Metaverse Space-based Exercise Video Distribution in Young Adults
This study explored whether exercise video distribution using metaverse space is effective in increasing physical activity among young people, along with mental health and locomotive function.
- Trial name
- NCT06019156
- Testing
- Exercise video distribution of Metaverse, Exercise video distribution of YouTube
- Where
- Japan
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Hiroshima University
Irritable Bowel Syndrome
Precision Pain Self-Management in Young Adults With Irritable Bowel Syndrome
This pilot project will provide foundational information about the contextual factors of irritable bowel syndrome (IBS) related pain (pain catastrophizing, perceived stress, reactivity pain sensitivity, genetic and microbiome) on…
- Trial name
- IBS-SM (NCT03332537)
- Testing
- Personalized IBS Pain SM
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- University of Connecticut
Major Depressive Disorder
Yoga for Young Women With Depression
The investigators examine whether adding yoga-based therapy (YBT) to treatment as usual (TAU) for young adult women (age 18-34 years) with a primary diagnosis of MDD leads to (1) greater reductions in symptoms and (2) greater…
- Trial name
- NCT03388177
- Testing
- Yoga-based therapy, Treatment as usual
- Where
- Netherlands
- Volunteers
- 170 people
- Sponsor
- University of Groningen
CGD
Evaluating the Transition From Pediatric to Adult Care Among Adolescents With Chronic Granulomatous Disease
Background: People who get chronic illnesses as children are living longer. When they turn 18, they switch from pediatric care to adult care. This can be a difficult change.
- Trial name
- NCT02233036
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
AML, Adult
Prospective Study on Severe Infections on Acute Myeloid Leukemia (AML) Patients
All patients receiving induction, consolidation and salvage chemotherapy, and autologous or allogeneic stem cell transplantation according to a strategy defined in the GIMEMA AML1310 protocol will be prospectively monitored for…
- Trial name
- AML1411 (NCT01570465)
- Testing
- Observation
- Where
- 46 sites in Italy
- Volunteers
- 144 people
- Sponsor
- Gruppo Italiano Malattie EMatologiche dell'Adulto
Acute Lymphoblastic Leukemia, in Relapse, Acute Lymphoblastic Leukemia, Refractory
Evaluation of CD19-Specific CAR Engineered Autologous T-Cells for Treatment of Relapsed/Refractory CD19+ Acute Lymphoblastic Leukemia
SJCAR19 is a research study seeking to evaluate the use of chimeric antigen receptor (CAR) T cell therapy, a type of cellular therapy, for the treatment of pediatric, adolescent and young adult patients with relapsed or…
- Trial name
- NCT03573700
- Testing
- Cyclophosphamide, Fludarabine, Mesna
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- St. Jude Children's Research Hospital
Meningococcal Disease
South Australian Meningococcal B Vaccine Herd Immunity Study
To estimate the effect on carriage, all year 10, 11, and 12 students will be offered 4CMenB vaccination in South Australia through schools over the study period with 50% of the students enrolled receiving the vaccine in 2017 and…
- Trial name
- B Part of It (NCT03089086)
- Testing
- Licensed 4CMenB vaccine
- Where
- Australia
- Volunteers
- 34,489 people, healthy volunteers welcome
- Sponsor
- University of Adelaide
Obesity
Telenutrition Center: Examining the Implementation of Behavioral Therapy for Obesity
The Telenutrition Center will use the Reach, Effectiveness, Adoption, Implementation and Maintenance (RE-AIM) Framework to assess the implementation of an evidence-based, intensive behavior therapy (IBT) for obesity intervention…
- Trial name
- NCT03855566
- Testing
- Intensive behavioral therapy for obesity
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Southern Mississippi
Hip Strain
Hip Manipulation in Young Adults With Groin, Lateral Hip or Buttock Pain
The purpose of the study is to identify the characteristics of young adults with pain in the groin, lateral hip or buttock who will benefit from manipulation of the hip.
- Trial name
- NCT02842801
- Testing
- Hip manipulation
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Texas Woman's University
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