Clinical trials: Young Adults
Heat Exposure, Healthy
Safe Indoor Temperature Limit for Fans
Extreme heat events are a significant global threat to health and wellbeing, and result in more morbidity and mortality than all other natural disasters combined.
- Conditions
- Heat Exposure, Healthy, Young Adults, Fans
- Trial name
- NCT06584903
- Testing
- Temperature Ramp Protocol
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Lakehead University
Healthy, Fatigue
Effects of Muscle Fatigue
This study aims to investigate the acute effects of fatigue in the tibialis anterior and gastrocnemius muscles on joint position sense, balance, pain threshold, and muscle elasticity in healthy young adults.
- Trial name
- NCT07009496
- Testing
- Tibialis Anterior Fatigue Protocol, Gastrocnemius Fatigue Protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Beykent
Relapsed Solid Tumors, Refractory Solid Tumors
A Study of Eribulin in Combination With Oral Irinotecan for Adolescent and Young Adult Patients With Relapsed or Refractory Solid Tumors
This IND-exempt Phase I trial will establish the recommended Phase II (RP2D) dose of eribulin in combination with fixed doses of oral irinotecan in adolescents and young adults with relapsed or refractory solid tumors.
- Trial name
- NCT02596503
- Testing
- Eribulin, Irinotecan, Cefixime
- Where
- 3 sites in United States
- Volunteers
- 2 people
- Sponsor
- University of Colorado, Denver
Health Behavior
"COACH" Study: Individualized COaching in Young Adult Cancer Survivors to Encourage Healthy Behaviors
The purpose of this study is to better understand the current lifestyle behaviors that people with a young adult cancer diagnosis have after treatment.
- Trial name
- NCT05434702
- Testing
- Digital Diet Diary, NHANES Food Frequency Questionnaire (FFQ), Fitbit data collection
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Influenza
The Human Mucosal Immune Responses to Influenza Virus (SLVP026)
This study will examine the immune responses to the seasonal influenza vaccine in single cells of the nasal passages when compared with cells in circulating blood.
- Trial name
- NCT03023553
- Testing
- Fluzone®, FluMist®
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Stanford University
Soft Tissue Sarcoma of the Lower Extremity, Bone Sarcoma of the Lower Extremity
Functional and Structural Outcomes Following Childhood Bone or Soft Tissue Sarcomas of the Lower Extremity
Soft tissue and bone sarcomas of the lower extremity pose significant challenges for affected individuals, often associated with considerable burden.
- Conditions
- Soft Tissue Sarcoma of the Lower Extremity, Bone Sarcoma of the Lower Extremity, Childhood and Adolescent Cancer
- Trial name
- FOCUS (NCT06737172)
- Where
- 2 sites in Germany
- Volunteers
- 18 people
- Sponsor
- Technical University of Munich
HIV-1-infection
ANCHORS Study: UH2 Project
According to the National HIV/AIDS Strategy, men who have sex with men (MSM), young adults, Black and Latino men and people in the Southern U.S.
- Trial name
- ANCHORS (NCT03360422)
- Testing
- Survey, Focus Group, Usability study
- Where
- United States
- Volunteers
- 673 people, healthy volunteers welcome
- Sponsor
- University of Florida
Obesity, Malignant Neoplasm
A Study to See if an iPhone Weight Management App Can Help Promote Weight Loss in Adolescents and Young Adults After a Stem Cell Transplant
This early phase I trial studies how well a behavioral weight loss intervention consisting of a smartphone application and coaching works for the promotion of weight loss in adolescents and young adults after a stem cell…
- Trial name
- NCT04453072
- Testing
- Interview, Media Intervention, Questionnaire Administration
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Jonsson Comprehensive Cancer Center
Asperger Syndrome, Autism Spectrum Disorder
Psychopathological Differences Between Asperger Syndrome and Schizotypal Disorder in an Adult Sample
The purpose of this study is to identify psychopathology (psychiatric symptoms) that can differentiate between Schizotypal Disorder (SD) and Asperger Syndrome (normal IQ, no language impairment Autism Spectrum Disorder) (AS) in…
- Conditions
- Asperger Syndrome, Autism Spectrum Disorder, Schizotypal Personality Disorder
- Trial name
- NCT02800681
- Testing
- Expert panel evaluation, Semi-structured psychopathological interviews, Self-administered rating scales
- Where
- 2 sites in Denmark
- Volunteers
- 59 people
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Diffuse Intrinsic Pontine Glioma (DIPG), Brain Stem Glioma
Brain Stem Gliomas Treated With Adoptive Cellular Therapy During Focal Radiotherapy Recovery Alone or With Dose-intensified Temozolomide (Phase I)
The standard of care for children with DIPG includes focal radiotherapy (RT) but outcomes have remained dismal despite this treatment.
- Trial name
- BRAVO (NCT03396575)
- Testing
- TTRNA-DC vaccines with GM-CSF, TTRNA-xALT, Cyclophosphamide + Fludarabine Lymphodepletive Conditioning
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Florida
Obesity
Low Intensity Weight Loss for Young Adults
This is a 3-arm randomized controlled trial to test the efficacy of three novel motivational approaches to weight loss with 18-25 year olds.
- Trial name
- REACH (NCT02736981)
- Testing
- Behavioral Weight Loss (BWL), BWL + Autonomous Motivation, BWL + Extrinsic Motivation
- Where
- United States
- Volunteers
- 382 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Sexual and Reproductive Health
The Investigation of Knowledge and Educational Demand of Sexual and Reproductive Health Among Cancer Survivors
The goal of this observational study is to explore the current situation and needs of adolescent and young adult cancer survivors for cancer-related reproductive health and fertility information.
- Trial name
- NCT05817981
- Testing
- Semi-structured interview, Questionnaires set
- Where
- China
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Pineoblastoma
Prospective Pilot Trial to Assess a Multimodal Molecular Targeted Therapy in Children, Adolescent and Young Adults With Relapsed or Refractory High-grade Pineoblastoma
Children, adolescents and young adults with relapsed or treatment refractory pineoblastoma (rPB) represent a group of patients with dismal prognosis for whom a recommended standard salvage therapy is currently not available.
- Trial name
- NCT02596828
- Testing
- Temozolomide, Irinotecan, Dasatinib
- Where
- Germany
- Volunteers
- 4 people
- Sponsor
- University of Regensburg
Stroke
Improving Work Ability of Young Adults With Stroke
This project will investigate effects of a novel theory-driven 6-week virtual Personal Resource Building and Inclusive Volunteering Intervention (PVI) on young stroke survivors' work ability, self-efficacy and psychosocial…
- Trial name
- NCT05902195
- Testing
- Personal Resource Building and Inclusive Volunteering Intervention (PVI), Usual care
- Where
- Hong Kong
- Volunteers
- 160 people
- Sponsor
- Chinese University of Hong Kong
Shigella, Diarrhea
First in Human Dose Escalation Study Evaluating the Safety and Immunogenicity of IVT's Shigella-04 Vaccine in Healthy Young Adults
Phase 1 trial to evaluate the Safety and Immunogenicity of Inventprise's (IVT) Shigella-04 in Healthy Young Adults
- Trial name
- NCT07205926
- Testing
- IVT Shigella-04
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Inventprise Inc.
Breast Cancer Stage 0, Breast Cancer Stage I
Optimizing Surgical Decisions in Young Adults With Breast Cancer
The goal of this study is to understand and improve the breast surgical decision-making process for young women newly diagnosed with breast cancer.
- Conditions
- Breast Cancer Stage 0, Breast Cancer Stage I, Breast Cancer Stage II, Breast Cancer Stage III
- Trial name
- CONSYDER (NCT06275126)
- Testing
- CONSYDER decision aid
- Where
- 4 sites in United States
- Volunteers
- 800 people
- Sponsor
- Weill Medical College of Cornell University
Healthy Young Adult
Relationship Between Sleep Quality, Sleep Duration, Heart Rate, and Step Number
This study aims to evaluate the relationship among sleep duration, heart rate, number of steps, and sleep quality.
- Trial name
- NCT05829525
- Testing
- Evaluation of sleep quality, sleep duration, heart rate and step count
- Where
- Turkey (Türkiye)
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Obesity and Overweight, Dysbiosis
Effect of Watermelon on Gut and Cardiometabolic Health
The goal of this clinical trial is to evaluate the effect of daily fresh watermelon consumption for 6-weeks on gut health, including microbiome diversity, gut barrier and immune function in young adults with overweight and…
- Trial name
- NCT06588218
- Testing
- Watermelon, Belvita Breakfast Sandwich + 12 oz Water
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Florida State University
Obesity, Morbid, Bariatric Surgery
Adjunct Phentermine + Topiramate After Bariatric Surgery in 12-24 Year Olds
The goal of this pilot study is to establish the feasibility and initial efficacy of the combination of phentermine and topiramate for adolescents and young adults who require additional risk reduction after bariatric surgery.
- Conditions
- Obesity, Morbid, Bariatric Surgery, Adolescent, Young Adult
- Trial name
- NCT04095104
- Testing
- Phentermine, Immediate Release Topiramate
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- University of Colorado, Denver
Acute Lymphobkastic Leukemia, Medication Adherence
The AYA Oncology Self-care Movement
This trial will test the impact of a social media intervention for improving oral chemotherapy adherence among adolescents and young adults (AYAs) with acute lymphoblastic leukemia.
- Trial name
- #AYAOSM (NCT07724652)
- Testing
- Educational Website, #AYAOSM
- Where
- 4 sites in United States
- Volunteers
- 200 people
- Sponsor
- Northwestern University
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