Clinical trials: Young Adults
Infections, Streptococcal
Evaluation of Pneumococcal Vaccine Formulations in Young Adults
The purpose of this study is to evaluate the safety, reactogenicity and immunogenicity of pneumococcal vaccines in young adults. Subjects will be vaccinated twice with an interval of two months.
- Trial name
- NCT00707798
- Testing
- Pneumococcal vaccine GSK2189242A, Pneumo 23™
- Where
- Belgium
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Emotional Resilience
The Student Living Lab: Intensive Longitudinal ESM Study for DP of ERFs to Stress in AYAs
This study aims at collecting continuous mobile-based devices data for determining emotional resilience factors and childhood abuse load profiles for stress and mental health problems.
- Trial name
- NCT06954064
- Testing
- No intervention will be applied.
- Where
- Romania
- Volunteers
- 343 people, healthy volunteers welcome
- Sponsor
- Babes-Bolyai University
Acoustic Stimulation
Acoustic Stimulation, Sleep, and Cognitive-Emotional Processes in Young Adults With Anxiety and Depression Symptoms
In this study, the investigators will recruit young adults (ages 18-25 years) with elevated anxiety/depression symptoms and sleep disturbance. Participants will complete two overnights in a sleep lab.
- Trial name
- SERS (NCT05802004)
- Testing
- Acoustic Stimulation (STIM), Daily acoustic stimulation (STIM2)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Michelle Stepan
Young Adults, Lymphoma, Non-Hodgkin
Fitness Assessment in Young Adults Recovered From Lymphoma
Regular physical activity (PA) is associated with maintaining body composition, increased cardiorespiratory capacity, muscle mass and bone mineral density.
- Conditions
- Young Adults, Lymphoma, Non-Hodgkin, Hodgkin Disease
- Trial name
- CUPCAKE (NCT05188755)
- Testing
- Indirect calorimetric test during submaximal exercise
- Where
- France
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Colorectal Cancer in Patients Under 50 Years of Age, Colorectal Cancer
Colorectal Cancer in Young Adults: Study of Incidence, Survival, and Prognostic Factors in Tarragona, Spain
We conducted an observational, descriptive, longitudinal and retrospective study of 59 patients under 50 years of age diagnosed with CRC in the province of Tarragona, between 2019 and 2024.
- Trial name
- CCR50 (NCT07026955)
- Testing
- colorectal cancer in patients over 50 years of age
- Where
- Spain
- Volunteers
- 59 people
- Sponsor
- HJ23
Diet Intervention
Effects of a Personalized Diet on Cardiometabolic, Microbiome and Metabolomics Profiles in Minority Young Adults
The proposed study has two primary objectives i.e. to examine how improvements in diet quality via a personalized dietary intervention 1) benefit cardiometabolic outcomes in young Black adults differentially compared to…
- Trial name
- NCT04635917
- Testing
- Personalized diet, Conventional dietary advice
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Alzheimer's Disease
Normative Values for Cognitive Testing and Alzheimer's Imaging Biomarkers in Young Adults
Biomarkers of Alzheimer's disease (AD) occupy an essential place in recently formulated diagnostic criteria for AD where their role is to identify the pathophysiological processes underlying cognitive impairment or to predict…
- Trial name
- NCT01609335
- Testing
- F-18 FDG, C-11 PiB
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Healthy
Study Evaluating a Combined Administration of Lecozotan SR and Citalopram in Young Healthy Subjects
To assess the safety and tolerability of lecozotan SR and citalopram when coadministred to healthy subjects.
- Trial name
- NCT00538889
- Testing
- Lecozotan SR, Citalopram
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Depression
Effects of Aerobic Exercise Modulation on Brain Physiology and Cognition in Young Adults With Depression
Major depressive depression (MDD) affects a quarter of young adults and is associated with marked global burden in this population.
- Trial name
- NCT04708691
- Testing
- Aerobic exercise
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Central Nervous System Tumor, Diffuse Intrinsic Pontine Glioma
Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System Tumors
This is a Phase 1 study of central nervous system (CNS) locoregional adoptive therapy with autologous CD4+ and CD8+ T cells lentivirally transduced to express a B7H3-specific chimeric antigen receptor (CAR) and EGFRt.
- Conditions
- Central Nervous System Tumor, Diffuse Intrinsic Pontine Glioma, Diffuse Midline Glioma, Ependymoma
- Trial name
- NCT04185038
- Testing
- SCRI-CARB7H3(s); B7H3-specific chimeric antigen receptor (CAR) T cel
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Seattle Children's Hospital
Knowledge, Behavior
Socialization To Enrich Participation & Support Sexuality for Young People With I/DD
The goal of this clinical trial is to test the effectiveness of a 6-week socialization and sex education curriculum (STEPS2) in young people (aged 16-27 years) with intellectual and developmental disabilities (I/DD), including…
- Trial name
- STEPS2 (NCT06231485)
- Testing
- STEPS2, STYH
- Where
- United States
- Volunteers
- 856 people, healthy volunteers welcome
- Sponsor
- City University of New York, School of Public Health
Suicidal Ideation
Dynamic Deconstructive Psychotherapy Versus Brief Intervention and Contact for Suicidal Adolescents and Young Adults
The purpose of this clinical trial is to assess whether 6 months of treatment with Dynamic Deconstructive Psychotherapy (DDP) is more effective for reducing thoughts of suicide in suicidal adolescents and young adults than usual…
- Trial name
- NCT05988489
- Testing
- Dynamic Deconstructive Psychotherapy (DDP), Brief Intervention and Contact (BIC)
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- State University of New York - Upstate Medical University
Stress, Stress-related Problem
Mental Health of the Polycrisis Generation
The goal of this observational, longitudinal study is to identify risk and protective factors that buffer the effects of individual daily stress and adaptation to global crises on the quality of life and mental health conditions…
- Conditions
- Stress, Stress-related Problem, Cumulative Trauma, Mental Health Issue
- Trial name
- NCT06515704
- Where
- 2 sites in Poland
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Jagiellonian University
Healthy Young Adults
Wii Fit as Balance Assessment and Training
Balance play a vital role to increase motor skills in healthy young adults. With increasing age balance control ability decreases,this decline can result as early as mid-30s.
- Trial name
- NCT04302155
- Testing
- balance-specific -games focusing on dynamic aspects of COP on Wii fit system., mini trampoline and inflatable discs group
- Where
- Pakistan
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Irritable Bowel Syndrome With Diarrhea, Fecal Microbiota Transplantation
Efficacy and Safety of FMT for the Treatment of IBS-D and Mental Health Comorbidity in Young Adults
The purpose of this study is to evaluate the efficacy and safety of Fecal Microbiota Transplantation compared with placebo in the treatment of Irritable Bowel Syndrome With Diarrhea (IBS-D) and Mental Health Comorbidity in Young…
- Conditions
- Irritable Bowel Syndrome With Diarrhea, Fecal Microbiota Transplantation, Mental Health Issue
- Trial name
- NCT06297421
- Testing
- Fecal Microbiota Transplantation
- Where
- China
- Volunteers
- 88 people
- Sponsor
- Shenzhen Hospital of Southern Medical University
Trapezius Muscle Strain
Comparative Effect of Graston Technique and Petrissage Technique on Tight Trapezius Muscles in Young Adults
This research aims to contribute valuable insights into the potential benefits of incorporating the portable wedge device into preventive or therapeutic interventions for calf-related musculoskeletal issues.
- Trial name
- NCT06437821
- Testing
- Petrissage, Graston Technique
- Where
- Pakistan
- Volunteers
- 46 people
- Sponsor
- Superior University
eTRE (Early Time Restricted Eating), lTRE (Late Time Restricted Eating)
Effect of Early Eating on Body Composition
To our knowledge, as of this day there are only four studies which examined the effects of eTRE with a duration of 12 weeks. There are no studies that examined this phenomenon beyond 12 weeks, one study that lasted five weeks and…
- Trial name
- NCT04679155
- Testing
- Eating Time Restriction
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Western University, Canada
Graft Versus Host Disease, Cancer
Extracorporeal Photopheresis for Acute Graft Versus Host Disease
The purpose of this research study is to evaluate the safety and feasibility of extracorporeal photopheresis (ECP) in the treatment of steroid-refractory acute graft-versus-host disease (GVHD) in children.
- Conditions
- Graft Versus Host Disease, Cancer, Stem Cell Transplantation
- Trial name
- NCT00179855
- Testing
- Extracorporeal Photopheresis
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Caffeine, Placebo
Acute Caffeine Intake in Young vs Older Adults
Evidence regarding the ergogenic effects of caffeine is well-established in young adults, but evidence in older adults remains scarce, particularly during dynamic resistance exercise.
- Trial name
- CAF+Age (NCT07711652)
- Testing
- Caffeine
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Alcala
Hyperhidrosis
A Pilot Study Exploring the Efficacy and Safety of Topical Oxybutynin 3% Gel for Primary Focal Hyperhidrosis in Adolescents and Young Adults
This is a single-center, prospective, open-label, outpatient pilot study evaluating the efficacy and tolerability of oxybutynin gel for axillary hyperhidrosis.
- Trial name
- NCT02633371
- Testing
- Oxybutynin 3% gel
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Colorado, Denver
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