Clinical trials: Young Adults
Alcohol Drinking, Problem Drinking
Testing Brief Personalized Feedback Integrating EMA Alcohol Cue Information
This study aims to develop a brief intervention that incorporates ecological momentary assessments (EMAs; i.e., four brief surveys per day for 17 days) to create personalized feedback targeting high-risk alcohol use among young…
- Trial name
- Project ACE (NCT05373706)
- Testing
- Alcohol Cue Reactivity Personalized Feedback Intervention
- Where
- United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University of Washington
Social Anxiety Disorder (SAD)
Effectiveness of an AI-Integrated Proactive Thought Control Intervention for Young Adults With Social Anxiety Disorder
Participants with Social Anxiety Disorder will be recruited from educational settings . After screening and informed consent, participants will be randomly assigned to PTC , ACG or CBT .The therapy session will be 8 session once…
- Trial name
- NCT07810348
- Testing
- AI-Proactive thought control, Cognitive Behavior Therapy, Active Control
- Where
- Pakistan
- Volunteers
- 75 people
- Sponsor
- Farah Shahzadi
Cancer
Genetic Testing in Young Adults With Cancer Study
The overarching goal of our research is to define an evidence-based, sustainable approach to identifying and managing genetic risk among young adults with cancer and their relatives.
- Trial name
- Gen-Y (NCT04533555)
- Testing
- Broad gene panel for young adult cancers, Standard
- Where
- United States
- Volunteers
- 749 people
- Sponsor
- University of Pennsylvania
Healthy
Expansion of Childhood Relationship Study to Young Adult Romantic Relationships
Background: An earlier study on child development focused on the relationship between children and their caregivers (usually mothers). It looked at how this relationship influenced children's social and mental development.
- Trial name
- NCT01866852
- Where
- United States
- Volunteers
- 259 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Haemophilia
Determinants and Consequences of the Transition to Adulthood Among Adolescents With Haemophilia
Severe haemophilia is a rare disease characterized by spontaneous bleedings from early childhood, which may lead to various complications especially in joints.
- Trial name
- TRANSHEMO (NCT02866526)
- Testing
- Patient questionnaire
- Where
- 29 sites in France
- Volunteers
- 277 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Oncology, Quality of Life
Measuring Health Related Quality of Life in AYAs
AIM1a: AYAs with cancer experience many challenges that impact their health-related quality of life (HRQOL) but few measures adequately capture AYAs' HRQOL in valid and reliable ways.
- Trial name
- PROMIS AYA (NCT03482778)
- Where
- 3 sites in United States
- Volunteers
- 165 people
- Sponsor
- Wake Forest University Health Sciences
Philadelphia Chromosome Negative Adult B-cell Acute Lymphoblastic Leukemia
Multicenter Trial Treatment of Philadelphia Chromosome Negative B-cell Acute Lymphoblastic Leukemia of Young Adults
The purpose of this study is to prospectively validate the new risk model, based on minimal residual disease (MRD) response level and oncogenetic status by comparing historical results of GRAALL-2005 with those of GRAALL-2014 in…
- Trial name
- GRAALL-2014/B (NCT02617004)
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Balance, Cognitive Load
Cognitive Load Effects on Balance and Postural Stability in Young Adults
The aim is to determine the impact of cognitive load on balance recovery mechanisms following perturbations in young adults. To evaluate how secondary task is influenced by cognitive load and vice versa.
- Trial name
- NCT06941714
- Testing
- Perturbation, Working Memory Task, Visual and Verbal Fluency Task
- Where
- Pakistan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Tobacco Use
Responses to Regulated E-Cigarette Advertisements
While conventional cigarette use continues to decline among youth and young adults, e-cigarette (EC) use is on the rise. Specifically, the investigators will conduct a randomized control trial (RCT) where young adults are…
- Trial name
- NCT05207033
- Testing
- Regulated ad condition, Unregulated ad condition
- Where
- United States
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Youth Mental Health, Psychological Distress in Adolescents and Young Adults
VIPeerAgent for Adolescent Mental Health
This three-arm parallel randomized controlled trial aims to evaluate the effectiveness of VIPeerAgent, a virtual peer support agent, in improving mental health outcomes among adolescents and young adults aged 14-25 years…
- Conditions
- Youth Mental Health, Psychological Distress in Adolescents and Young Adults, Early Intervention
- Trial name
- NCT07778758
- Testing
- Virtual Peer Agent Intervention, Human peer mentor
- Where
- China
- Volunteers
- 234 people
- Sponsor
- Sun Yat-sen University
Solid Tumor or Lymphoma
Supportive Care Needs of Former Child, AYA Cancer Patients, and of Their Parents: Evaluation During Long-term Follow-up
Each year, there are 2100 new cases of cancer in children and adolescents/young adults (AYA) in France. Due to a significant improvement in the effectiveness of therapies, the survival rate of all types of cancer combined after 5…
- Trial name
- ExPEDAJAC (NCT04711733)
- Testing
- Interview, Self-report questionnaire, Medical consultation
- Where
- France
- Volunteers
- 99 people
- Sponsor
- Centre Leon Berard
Cancer, Depression, Anxiety
Identification of Anxiety and Depression in Adolescents/Young Adults (AYA) With Cancer
This is a prospective, multisite (but all within the UTSW IRB), observational study assessing the relationship of hope to anxiety and depression, QoL, and social support over time in the first year after cancer diagnosis or…
- Trial name
- NCT04589052
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- University of Texas Southwestern Medical Center
Cancer, Young Adult
Symptom Management for YA Cancer Survivors
Symptom interference is common for survivors of young adult cancer (aged 18-39 at diagnosis) and impacts their abilities to achieve normative life goals (e.g., education, careers, independence, romantic/social relationships) as…
- Conditions
- Cancer, Young Adult, Pain, Psychological Distress
- Trial name
- NCT04035447
- Testing
- Behavioral Symptom Management for Young Adult Cancer Survivors
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Duke University
Obesity, Adolescent
Young Adults With Early-onset Obesity Treated With Semaglutide
Introduction: The increasing prevalence of obesity is particularly pronounced among adolescents. Currently available treatment options consist of structured lifestyle interventions.
- Trial name
- RESETTLE (NCT05574439)
- Testing
- TCOC treatment, Semaglutide 3 mg/ml
- Where
- 2 sites in Denmark
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- Signe Torekov
Gingival Inflammation
Lactobacillus Reuteri Strains for Gingivitis Reduction
The aim of the present study was to investigate the potential beneficial effects in volunteer young adults of orally administered L. reuteri (DSM 17938 and ATCC PTA 5289) on gingival inflammation.
- Trial name
- NCT06234839
- Testing
- L. reuteri (DSM 17938 and ATCC PTA 5289) in form of oral tablets
- Where
- Mexico
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de San Luis Potosí
Juvenile Idiopathic Arthritis
Safety and Effectiveness of Rilonacept for Treating Systemic Juvenile Idiopathic Arthritis in Children and Young Adults
Systemic juvenile idiopathic arthritis (SJIA) is a type of arthritis that typically occurs before 16 years of age. SJIA usually involves heat, pain, swelling, and stiffness in the body's joints.
- Trial name
- NCT00534495
- Testing
- Rilonacept
- Where
- United States
- Volunteers
- 71 people
- Sponsor
- Montefiore Medical Center
Type 1 Diabetes
Healthy And Positive Pathways for Young People With Type 1 Diabetes (HAPPY T1D)
In this 2-year randomized clinical trial, we will implement and assess the impact of a behavioral/psychoeducational intervention to reduce diabetes distress and improve glycemic outcomes in adolescents and young adults, aged…
- Trial name
- NCT05413239
- Testing
- Psychoeducation to reduce diabetes distress and improve glycemic outcomes
- Where
- 2 sites in United States
- Volunteers
- 217 people
- Sponsor
- Joslin Diabetes Center
Tobacco Use Behavior, Nicotine Dependence Tobacco Product
§SMOKE Nicotine and Tobacco Youth Cohort
The §SMOKE Cohort Study aims to improve understanding of tobacco and nicotine use among adolescents and young adults in Denmark.
- Conditions
- Tobacco Use Behavior, Nicotine Dependence Tobacco Product, E-Cigarette Use, Smoking ( Cigarette)
- Trial name
- NCT07910331
- Where
- Denmark
- Volunteers
- 10,000 people
- Sponsor
- University of Southern Denmark
Substance Use Disorders
Smartphone Addiction Recovery Coach for Young Adults (SARC-YA) Experiment
At discharge from outpatient treatment, researchers will recruit 300 young adults and randomly assign them to recovery support as usual control condition or the Smartphone Addiction Recovery Coach for Young Adults (SARC-YA)…
- Trial name
- SARC-YA (NCT03301012)
- Testing
- Recovery support as usual, Smartphone assisted relapse prevention
- Where
- 2 sites in United States
- Volunteers
- 237 people, healthy volunteers welcome
- Sponsor
- Chestnut Health Systems
Obstructive Sleep Apnea
Extracellular microRNA: Biomarkers of Endothelial Dysfunction in Obese Adolescents & Adults With Obstructive Sleep Apnea
Using a prospective observational approach and a clinical trial design comparing the effectiveness of continuous positive airway pressure to diet and exercise, investigators plan to evaluate how obstructive sleep apnea (OSA)…
- Trial name
- NCT03546751
- Testing
- Continuous Positive Airway Pressure, Diet And Exercise
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
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