Clinical trials: Young Adults
HIV Infections
Blood Levels of Abacavir in HIV Infected Adolescents
The way abacavir (ABC) behaves in the body differs between children and adults, but little is known about ABC in adolescents. It is unclear if adult doses of ABC are appropriate for adolescents.
- Trial name
- NCT00087945
- Testing
- Abacavir sulfate, Abacavir sulfate, lamivudine, and zidovudine
- Where
- 20 sites in United States, Puerto Rico
- Volunteers
- 30 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Type 1 Diabetes
DiaBetter Together for Young Adults With Type 1 Diabetes
DiaBetter Together is a strengths-based peer support intervention delivered to young adults (age 17-25) by trained Peer Mentors (age 20-35) during the transition between pediatric and adult diabetes care.
- Trial name
- DiaBetter (NCT04247620)
- Testing
- DiaBetter Together, Peer Mentor Delivery
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- Baylor College of Medicine
Anxiety, Stress
Assessment of Stress and Associated Factors Among Young Adults During the COVID-19 Pandemic
Since the onset of COVID-19, studies conducted on the general population have shown an increase in the use of antidepressants and anxiolytics, a rise in domestic violence, and heightened demand for peri-urban housing offering…
- Conditions
- Anxiety, Stress, COVID - 19
- Trial name
- JADESTRESS (NCT07845396)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 1,322 people, healthy volunteers welcome
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
B-cell Acute Lymphoblastic Leukemia, Diffuse Large B-cell Lymphoma
Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)
Substudy 01A is part of a platform study. The purpose of this study is to assess the efficacy and safety of zilovertamab vedotin in pediatric participants with relapsed or refractory B-cell acute lymphoblastic leukemia (B-ALL)…
- Conditions
- B-cell Acute Lymphoblastic Leukemia, Diffuse Large B-cell Lymphoma, Burkitt Lymphoma, Neuroblastoma
- Trial name
- NCT06395103
- Testing
- Zilovertamab vedotin
- Where
- 71 sites in United States, Australia and 21 more
- Volunteers
- 90 people
- Sponsor
- Merck Sharp & Dohme LLC
Acute Appendicitis
The Performance of the APPY1 Test in the Evaluation of Possible Acute Appendicitis
This study will consist of a brief interaction with the subject or parent or guardian to obtain consent, collect a blood sample, medical history, and physical examination of those who meet the inclusion criteria.
- Trial name
- APPY1 (NCT01652170)
- Where
- 29 sites in United States
- Volunteers
- 2,201 people
- Sponsor
- Venaxis, Inc.
Central Nervous System Malignancies, Ependymoma
Phase I Study of 5-Fluorouracil in Children and Young Adults With Recurrent Ependymoma
This is a phase I study to investigate the safety and pharmacokinetics of weekly 5-fluorouracil (5-FU) administered as a bolus dose in children and young adults with recurrent or refractory ependymoma.
- Trial name
- SJREFU (NCT01498783)
- Testing
- 5-fluorouracil
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- St. Jude Children's Research Hospital
Diabetes Mellitus, Type 1
Determinants of Metabolic Control in Children With Type 1 Diabetes Mellitus
A good metabolic control of type 1 diabetes mellitus (T1DM) is crucial to avoid long-term complications associated with the disease.
- Trial name
- NCT06317454
- Testing
- Blood and saliva analysis
- Where
- Italy
- Volunteers
- 800 people
- Sponsor
- IRCCS Burlo Garofolo
Acute Vaso Occlusive Crisis (VOC)
L-citrulline Injection in Patients Aged 6-21 Years Old with Sickle Cell Disease Presenting with Vaso-Occlusive Crisis (VOC)
The purpose of this study is to determine if intravenous L-citrulline can abrogate an active vaso-occlusive crisis in sickle cell disease, resulting in decreased pain, reduction or elimination of opiate usage, and reduction or…
- Trial name
- NCT04852172
- Testing
- L-citrulline, D5 1/2NS
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Asklepion Pharmaceuticals, LLC
Refractory Low-grade Gliomas, Recurrent Low-grade Gliomas
Study Of Vinblastine in Combination With Nilotinib in Children, Adolescents and Young Adults
Multicenter, open label, prospective study including successively a phase I trial and then a phase II trial Phase I : Open label, non-randomized, sequential dose escalation of both drugs, vinblastine and nilotinib.
- Trial name
- VINILO (NCT01884922)
- Testing
- Nilotinib, Vinblastine
- Where
- 8 sites in Austria, Denmark and 6 more
- Volunteers
- 35 people
- Sponsor
- Gustave Roussy, Cancer Campus, Grand Paris
Hypertension
A Pilot Randomized Controlled Trial to Reduce Salt Intake Among Hypertensive Young Adults in Hong Kong
A pilot randomized controlled trial will be conducted to investigate the feasibility and effectiveness of a salt intake reduction intervention to young hypertension patients in Hong Kong who had high salt intake.
- Trial name
- NCT02920437
- Testing
- Four-week weekly intervention to reduce salt intake, Usual government pamphlets
- Where
- China
- Volunteers
- 19 people
- Sponsor
- The University of Hong Kong
Peripheral Neuropathy
Innovative Treatment of Chemotherapy-Induced Painful Peripheral Neuropathy in Adolescents and Young Adults With Cancer: A Two Arm Pilot Study
To evaluate the efficacy and safety of Scrambler therapy (ST) for chemotherapy-induced painful peripheral neuropathy (CIPN), and the impact of ST on physical functioning and quality of life (QoL) in adolescents and young adults…
- Trial name
- NCT05357469
- Testing
- Immediate St (Scrambler Therapy), Waitlist ST (Scrambler Therapy)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- M.D. Anderson Cancer Center
Osteoid Osteoma, Benign Bone Tumor
MR-Guided High Intensity Focused Ultrasound for Pain Management Of Osteoid Osteoma & Benign Bone Tumors in Children and Adults
The Philips Sonalleve HIFU system is expected to be efficacious in reducing pain scores in patients with painful osteoid osteoma and other benign bone tumors, and in reducing their pain medication usage.
- Conditions
- Osteoid Osteoma, Benign Bone Tumor, Pain
- Trial name
- NCT02618369
- Testing
- MR-Guided High Intensity Focused Ultrasound
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- The Hospital for Sick Children
Healthy Young Adults, Body Image
Strong Minds: A Digital Intervention Targeting Body Image and Psychological Well-being Among Adolescent Male Fitness Club Members
The purpose of this study is to evaluate whether a digital intervention can improve body image and psychological well-being among adolescent boys who attend fitness clubs.
- Conditions
- Healthy Young Adults, Body Image, Psychological Well-being, Body Dissatisfaction
- Trial name
- Strong Minds (NCT07789405)
- Testing
- Website
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Norwegian School of Sport Sciences
Central Nervous System Neoplasm, Hodgkin Lymphoma
Mobility and Physical Activity in Adolescent and Young Adult Cancer Patients or Survivors at Risk for Cardiovascular Morbidity and Frailty, The MOBILE AYA Study
This study attempts to learn more about the activity levels of adolescent and young adult (AYA) cancer patients or survivors at risk for cardiovascular morbidity and frailty by using a smartphone application called Beiwe.
- Conditions
- Central Nervous System Neoplasm, Hodgkin Lymphoma, Malignant Solid Neoplasm, Non-Hodgkin Lymphoma
- Trial name
- NCT05169151
- Testing
- Smartphone Application
- Where
- United States
- Sponsor
- M.D. Anderson Cancer Center
Adolescent Cancer Survivors, Childhood Cancer Survivors
IMpact of Mind-body Therapies (HYpnosis and Relaxation) on Anxiety in Children, Adolescents and Young Adults Who Had Been Treated in ONcology. Multicenter Study.
In France today, it is estimated that one in 850 people aged between 20 and 45 has been cured of cancer in childhood. Some descriptive studies have established that cancer diagnosis and treatment can affect psychological health…
- Conditions
- Adolescent Cancer Survivors, Childhood Cancer Survivors, Anxiety
- Trial name
- HARMONY-Impact (NCT07380672)
- Testing
- 10 mind-body therapy sessions (hypnosis or relaxation, depending on the patient's choice), 9 sessions of standard psychological care
- Where
- 5 sites in France
- Volunteers
- 558 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Diabetes Mellitus
Feasibility of Delivering a Complex Behavioral Intervention for Young Adults With Diabetes Via Telehealth
Feasibility of a Complex Behavioral Intervention for Young Adults with Diabetes: The Resilient, Empowered, Active Living-Telehealth (REAL-T) Study will evaluate the feasibility of implementing a diabetes management intervention…
- Trial name
- NCT03333772
- Testing
- REAL-T Intervention
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Southern California
Glioblastoma
Evaluate the Role of Anthracycline After Radio Therapy in Patients With Glioblastoma (pGBM).
Glioblastoma (GBM) and diffuse intrinsic bridge gliomas (DIPG) only the most aggressive forms of cancer, and their prognosis remains bleak.
- Trial name
- NCT06297512
- Testing
- Radiotherapy, Temozolomide, Doxorubicin
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Iacopo Sardi
Bone Resorption, Bone and Bones
Combination Plant-Based Protein and Marine-Based Multi-Mineral Supplement and Bone Remodeling in Young Adults
Nutrient intake of calcium and protein are known to function as regulators of bone remodeling. Specifically, a balanced rate of bone resorption and bone formation (i.e.
- Trial name
- NCT05533502
- Testing
- Combined Plant-Based Protein and Marine-Based Multi-Mineral Supplement
- Where
- Ireland
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Limerick
Loneliness
Evaluating the Effectiveness of Interventions to Reduce Loneliness in Chinese Young Adults
This study aims to evaluate the effectiveness of a group-based Positive Affect (PA) intervention compared to an active control condition, Social Skills Training (SST), in reducing loneliness among young adults in Hong Kong and…
- Trial name
- NCT07543653
- Testing
- Group-based Positive Affect Intervention, Group-based Social Skills Training
- Where
- Hong Kong
- Volunteers
- 100 people
- Sponsor
- Education University of Hong Kong
E-Cig Use
The Impact of Policies Regarding E-cigarette on Adolescents and Young Adults' Cognition and Behavior for E-cigarette
Based on the Knowledge，Attitude，Belief and Practice model(KABP model), this study intends to use a mixed method to explore the influencing mechanism of youth and adolescents' cognition and behavior for e-cigarette before and…
- Trial name
- NCT05482581
- Testing
- Questionnaires set
- Where
- China
- Volunteers
- 453 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
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