Clinical trials: Young Adults
Solid Tumor, Lymphoma
A Study of Surufatinib in Combination With Gemcitabine in Pediatric, Adolescent, and Young Adult Patients With Recurrent or Refractory Solid Tumors
The purpose of this study is to evaluate the safety and tolerability of surufatinib, thereby identifying the Maximum Tolerated Dose (MTD) and/or Recommended Phase 2 Dose (RP2D) of surufatinib administered in combination with…
- Conditions
- Solid Tumor, Lymphoma, Osteosarcoma, Ewing Sarcoma
- Trial name
- NCT05093322
- Testing
- Surufatinib in combination with Gemcitabine
- Where
- 11 sites in United States
- Volunteers
- 13 people
- Sponsor
- Hutchmed
Hypermobility, Joint, Hypermobility Syndrome
Exercise in Patients With Hypermobile Joints and Knee Pain
Pain associated with knee joint hypermobility is common in the adult population, but evidence on treatment is sparse. This study investigates if high-load resistance training is superior to usual care in improving…
- Conditions
- Hypermobility, Joint, Hypermobility Syndrome, Knee Discomfort
- Trial name
- HIPEr-Knee (NCT06277401)
- Testing
- Neuromuscular training for the knee, High-load strength training for the knee
- Where
- 2 sites in Denmark
- Volunteers
- 80 people
- Sponsor
- University of Southern Denmark
Patellofemoral Pain Syndrome
Effects of Hip and Knee Exercises on Knee Pain in Young Adult Females With Long-standing Patellofemoral Pain
Patellofemoral pain (PFP) is highly prevalent in both adolescent and adult populations and as much as 91% of those affected experience ongoing knee pain for up to 20 years after the initial diagnosis.
- Trial name
- NCT03054701
- Testing
- Hip specific resistance exercise, Knee specific resistance exercise
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Aalborg University
Epilepsy
Evaluation of the Pharmacokinetics, Safety, and Tolerability of TPM XR as Adjunctive Therapy in Pediatric Subjects With Epilepsy
Multidose, Open-label, Multi-center Study to examine the steady state pharmacokinetics of TPM XR, as well as, safety and tolerability of repeated oral dosing in pediatric subjects with epilepsy.
- Trial name
- NCT01284530
- Testing
- TPM XR
- Where
- 10 sites in United States
- Volunteers
- 30 people
- Sponsor
- Supernus Pharmaceuticals, Inc.
Transgender Persons, Health Services for Transgender Persons
THE GUIDE: Transforming Health for Young Adults Using Interventions to Drive Engagement
This is a randomized controlled trial to test the effectiveness of an interactive educational app-based digital intervention that provides knowledge and support to transgender and gender-diverse (TGD) young adults ages 18-29…
- Conditions
- Transgender Persons, Health Services for Transgender Persons, Gender Identity
- Trial name
- NCT06177600
- Testing
- Interactive educational digital platform for transgender and gender-diverse (TGD) young adults and caregivers
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Stress, Psychological Factors
Body Awareness Therapy in High Stressed Young Adults: Effects on Function, Balance, Sleep and Mood
Body Awareness Therapy (BAT) is a holistic approach to human movement that considers the physical, physiological, psychological, and existential aspects of human existence.
- Conditions
- Stress, Psychological Factors, Sleep, Postural Balance
- Trial name
- NCT07045792
- Testing
- Body Awareness Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mustafa Kemal University
HIV (Human Immunodeficiency Virus), Sexually Transmitted Diseases
Reality Check: An HIV Risk Reduction Serial Drama
African Americans have considerably higher rates of HIV infections than do White, Hispanic, Asian, and Native Americans. African Americans accounted for 59% of all diagnoses of HIV infection among youth (13-24 years of age) in…
- Trial name
- RC (NCT03352219)
- Testing
- Reality Check, Physical Activity Attention Control
- Where
- United States
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Malignant Neoplasm
Resistance Training Program and Cardiovascular Exercise in Increasing Muscle Mass in Adolescent and Young Adult Stem Cell Transplant Survivors
This pilot trial studies how well a resistance training program and cardiovascular exercise work in increasing muscle mass in adolescent and young adult stem cell transplant survivors.
- Trial name
- NCT03672981
- Testing
- Exercise Intervention, Quality-of-Life Assessment, Questionnaire Administration
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Fred Hutchinson Cancer Center
Healthy Young Adults
Acute Effect of Immersive VR Technology on Postural Control and Reaction Time in Young Adults
This study investigates the acute effects of short-term immersive virtual reality (VR) exposure on sensory organization and reaction time in young adults aged 18-25 years. It is designed as a randomized controlled trial.
- Trial name
- NCT07709065
- Testing
- Virtual reality gamified motor coordination task
- Where
- Poland
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- University of Rzeszow
Mental Health Impairment, Mental Health Disorder
The MILESTONE Study: Improving Transition From Child to Adult Mental Health Care
This study evaluates the longitudinal health and social outcomes of adolescent mental health service users who are at the transition boundary of their child and adolescent mental health service, and whether the implementation of…
- Trial name
- MILESTONE (NCT03013595)
- Testing
- TRAM feedback
- Where
- 10 sites in Belgium, Croatia and 6 more
- Volunteers
- 1,000 people
- Sponsor
- University of Warwick
Cancer, Youth Cancer
Pilot Study of Mindset Moments Among Adolescent and Young Adult Cancer Survivors
The purpose of this study is to evaluate the feasibility and acceptability of the Mindset Moments™ (MM™) program in managing psychological distress and resiliency in adolescent and young adult cancer survivors.
- Conditions
- Cancer, Youth Cancer, Young Adult Cancer, Distress, Psychological
- Trial name
- NCT06732375
- Testing
- Mindset Moments
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Duke University
Cancer, Insomnia Chronic
Device Feasibility and Acceptability to Improve Insomnia in Cancer
Sleep disruption is common among young adult cancer survivors for a variety of reasons. Cognitive behavioral therapy for insomnia (CBT-I) has been shown to improve chronic sleep disorders.
- Trial name
- NCT05875129
- Testing
- VAVA prototype
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Medstar Health Research Institute
Advanced Cancer
A Phase I Trial of DM-CHOC-PEN in Adolescent and Young Adult (AYA) Subjects With Advanced Cancers
4-Demethyl-4-cholesteryloxycarbonylpenclomedine (DM-CHOC-PEN) is a polychlorinated pyridyl cholesterol carbonate that is lipophilic, electrically neural, crosses the blood brain barrier (BBB), ability to localize in intracranial…
- Trial name
- NCT02889445
- Testing
- 4-Demethyl-4-cholesteryloxycarbonylpenclomedine
- Where
- United States
- Sponsor
- DEKK-TEC, Inc.
Performance Improvement in Beginner Archers
The Effect of Imagery Exercises on Attention and Performance in Olympic Archers
The goal of this clinical trial is to for beginners in archery in to examine the effects of Imagination and breathing exercises given in addition to 8-week archery training on archery target score, postural sway, attention, hand…
- Trial name
- NCT06739681
- Testing
- Routine Intervention, Mental Imagery Intervention, Breathing Exercise Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Medipol University
Eating Disorders, Anorexia Nervosa
Developing an Artificial Intelligence (AI) Chatbot for Adolescents and Young Adults With Eating Disorders
The goal of this study is to develop and refine an artificial intelligence (AI)-powered Exposure Therapy for Eating Disorders chatbot web-app that effectively engages adolescents and young adults and decreases anxiety about…
- Conditions
- Eating Disorders, Anorexia Nervosa, Bulimia Nervosa, Binge-Eating Disorder
- Trial name
- NCT07237607
- Testing
- "Exp-ED" Digital Exposure-Therapy Chatbot app
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Milton S. Hershey Medical Center
Young Healthy Adults
Basic Body Awareness Therapy for Healthy Young Adults
Background: Musculoskeletal pain, impaired postural control, and reduced movement quality are increasingly observed among young adults, partly due to sedentary lifestyles and insufficient physical activity.
- Trial name
- NCT07652086
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Özge ÇANKAYA
Bone Cysts
Safety and Tolerability of I-040302 in Children and Young Adults With Solitary Bone Cysts
This is a randomised, controlled, open-label study of a single intralesional administration of I-040302 or a single bone marrow aspirate or a single steroid injection (methylprednisolone).
- Trial name
- NCT00459641
- Testing
- I-040302, Standard of Care
- Sponsor
- Kuros Biosurgery AG
B-cell Acute Lymphoblastic Leukemia, Acute Lymphocytic Leukemia, Pediatric
CD19 T-CAR for Treatment of Children and Young Adults With r/r B-ALL
The purpose of this study is to evaluate the safety and efficiency of autologous CD19 CAR-T lymphocytes in a cohort of pediatric and young adult patients with relapsed /refractory B-lineage acute lymphoblastic leukemia
- Trial name
- NCT03467256
- Testing
- Chimeric Antigen Receptor T-Cell Therapy, Fludarabine, Cyclophosphamide
- Where
- Russia
- Volunteers
- 18 people
- Sponsor
- Federal Research Institute of Pediatric Hematology, Oncology and Immunology
Hazardous Drinking, Harmful Alcohol Use
Telephone-Based Acceptance and Commitment Therapy for Young Adult Hazardous Drinkers
The goal of this clinical trial is to learn if telephone-based Acceptance and Commitment Therapy (ACT) works to help young adults with hazardous or harmful alcohol use quit drinking.
- Trial name
- NCT07621822
- Testing
- Telephone-Based Acceptance and Commitment Therapy (ACT), Waitlist control with Telephone-Based Social Support
- Volunteers
- 288 people
- Sponsor
- The Hong Kong Polytechnic University
Chronic Disease, Adolescent Asthma
Community Connections Through Native Hawaiian Cultural Values to Strengthen Youth Resilience, Health, and Well-Being
The goal of this pilot clinical trial is to learn if a community referral program can improve services for youth with mental health and chronic health conditions in a predominantly Native Hawaiian and Pacific Islander community.
- Conditions
- Chronic Disease, Adolescent Asthma, Obesity & Overweight, Youth Mental Health
- Trial name
- Kamaehu (NCT07536256)
- Testing
- Community Referral to Kaiona Programs
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Waianae Coast Comprehensive Health Center