Clinical trials: Young People
Serious Game, Asthma in Children
Serious gaMes as Emerging E-health Interventions for Young People With neurologicaL or rEspiratory disoRders
The main purpose of 'Serious Games' (SG) is to provide opportunities for constructive learning and training. They are well-accepted instruments in therapeutic interventions and have been found to be efficient to improve cognitive…
- Conditions
- Serious Game, Asthma in Children, Children, Only
- Trial name
- SMILER (NCT05974917)
- Testing
- Serious Game (SG)
- Volunteers
- 30 people
- Sponsor
- Istituto di Farmacologia Traslazionale - sede di Palermo, Consiglio Nazionale delle Ricerche (CNR)
Adolescent Behavior
An Integrated Smoking Cessation and Alcohol Intervention Among Hong Kong Chinese Young People
Current smoking cessation interventions are focused only on smoking behaviors, and drinking habits are generally overlooked. The aims of the project is to examine the feasibility of implementing an integrated smoking cessation…
- Trial name
- NCT04875546
- Testing
- Standard treatment, Integrated Intervention, Control
- Where
- Hong Kong
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Sickle Cell Disease
Patient and Public Involvement and Engagement in Research With Children and Young People With Sickle Cell Disorder and Their Families
Aim: To co-produce resources for inclusive and equitable Patient and Public Involvement and Engagement in research on life-limiting conditions, with children and young people with sickle cell disorder and their families.
- Trial name
- NCT06293222
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- King's College London
White Spot Lesion
P11-4 and Nanosilver Fluoride Varnish in Treatment of White Spot Carious Lesions
Background: Great efforts have been undertaken for dental caries prevention. Among the recent remineralizing materials, Nano silver fluoride varnish products which are based on nanotechnology have been proposed for "repairing"…
- Trial name
- NCT04929509
- Testing
- self-assembling peptide, nanosilver fluoride varnish, sodium fluoride varnish
- Where
- Egypt
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Hams Hamed Abdelrahman
Alcoholism
Chicago Social Drinking Project
This study attempts to elucidate the factors that contribute to escalation and maintenance of excessive ethanol drinking in young adults by: 1.
- Trial name
- CSDP (NCT00961792)
- Testing
- Ethanol, Diphenhydramine, Caffeine
- Where
- United States
- Volunteers
- 800 people
- Sponsor
- University of Chicago
Cardiovascular Diseases, Heart Diseases
Diet Modification and Blood Pressure in Young People
To determine the effects of diet modification on blood pressure, blood cholesterol, and bone density in healthy young people.
- Trial name
- NCT00005167
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Accidental Overdose of Opiate
Rapid Self-Testing to Prevent Fentanyl Overdose Among Young People Who Use Drugs
The research team will enroll 100 young adults who use cocaine, heroin, inject drugs, or purchase prescription medications on the illicit market in a pilot study to be known as the Rhode Island Young Adult Prescription and…
- Trial name
- RAPiDS2 (NCT03373825)
- Testing
- Take home rapid drug test
- Where
- United States
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Brown University
Depression
African Youth in Mind (Y-MIND) - Pilot Feasibility Trial of a Brief Psychological Intervention for Young People With Depression in Zimbabwe
The overarching aim of this single-arm pilot study is to assess the feasibility of implementing a psychological intervention (Y-MIND), delivered by lay counsellors, for the treatment of depression among young people aged 15-24 in…
- Trial name
- Y-MIND (NCT06858215)
- Testing
- Y-MIND Intervention
- Where
- Zimbabwe
- Volunteers
- 50 people
- Sponsor
- King's College London
Asthma
Self-management Intervention to Improve Adolescents' Asthma Control
Approximately 1.1 million children and young people in the United Kingdom (UK) are living with asthma, making it the most common chronic disease in children in the UK.
- Trial name
- MAIS (NCT03536416)
- Testing
- My Asthma in School
- Where
- United Kingdom
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Type 1 Diabetes, Coronary Artery Calcification
Cardiovascular Risk Stratification in Young People With Type 1 Diabetes
The aim of the study is to compare ESC recommendations on cardiovascular (CV) risk stratification with the achievement of a CAC (Coronary Artery Calcification).
- Trial name
- CACD1 (NCT05283538)
- Testing
- Coronary Artery Calcification Realization
- Where
- France
- Volunteers
- 91 people
- Sponsor
- Poitiers University Hospital
Emotional Regulation
Acceptability and Feasibility of an Adapted DBT-informed Skills Group for Gender Diverse Young People Co-delivered in a Charity Setting
Gender diverse (e.g. trans or non-binary) young people are at higher risk of self-harm and may be more likely to access support through gender-diverse-specific 3rd sector charities.
- Trial name
- NCT06237608
- Testing
- Dialectical behavioural therapy (DBT)-informed skills group
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- King's College London
Complex Care, Medical Complexity
Complexity in Health, Education, and Social Support for Children and Young People With Life-limiting Conditions.
Children and young people (CYP) with life-limiting conditions represent a growing population with complex care needs that span health, education, and social care systems.
- Conditions
- Complex Care, Medical Complexity, Pediatrics, Life-limiting Illness
- Trial name
- CHESS (NCT07102433)
- Testing
- Children and young people with life-limiting conditions, their parents/carers, and professionals across healthcare, education, and social care sectors.
- Where
- 5 sites in United Kingdom
- Volunteers
- 170 people
- Sponsor
- King's College London
Depression, Anxiety
Generative Artificial Intelligence Intervention and Individual Psychological Counseling on Emotional Distress in Young Adults
This randomized controlled trial aims to evaluate the effectiveness of an AI-based mental health chatbot, Emohaa, in reducing symptoms of depression, anxiety, insomnia, and academic burnout among young adults experiencing…
- Trial name
- NCT06992180
- Testing
- Generative Artificial Intelligence Intervention, Individual Psychological Counseling
- Where
- China
- Volunteers
- 222 people
- Sponsor
- Central University of Finance and Economics, China
Cardiovascular Risk Factor
Determinants of Adolescent, Now Young Adults, Social Well-being and Health: Longitudinal Follow-up
Black and ethnic minority groups living in the UK experience high rates of chronic diseases such as diabetes, hypertension and heart disease, general morbidity and poor mental health.
- Trial name
- DASH (NCT03283332)
- Testing
- No intervention
- Volunteers
- 6,643 people, healthy volunteers welcome
- Sponsor
- King's College London
Obesity, Adolescent
mHealth Biometrics for Young People With Obesity (MOTIVATE- LOOP)
The investigators aim to undertake a feasibility randomised controlled trial (RCT) to investigate whether mHealth technology, allowing biometric informed feedback and coaching on exercise and PA, can be incorporated into the…
- Trial name
- MOTIVATE-L (NCT04854915)
- Testing
- LOOP + mHealth technology assisted exercise counselling, LOOP Only
- Where
- 2 sites in United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Liverpool John Moores University
Emotional Difficulties
A Feasibility Trial of Power Up
There is an increasing demand for digital tools to empower young people with mental health difficulties (NHS England, 2015). Digital information, advice and mood tracking tools are increasingly being used to support child mental…
- Trial name
- NCT02987608
- Testing
- Power Up
- Where
- 3 sites in United Kingdom
- Volunteers
- 120 people
- Sponsor
- University College, London
HIV, Mental Health
Reducing Stigma and Building Employability Skills for Young People With HIV in Zambia
The goal of this clinical trial is to learn if a program called Kupambana can improve mental health and HIV care outcomes in young people with HIV in Zambia by combining stigma-reduction support with financial and job-skills…
- Conditions
- HIV, Mental Health, Treatment Adherence
- Trial name
- NCT07732660
- Testing
- Stigma Reduction Support Group (SRSG), Financial Literacy, Technical and Vocational Education and Training (TVET)
- Where
- Zambia
- Volunteers
- 100 people
- Sponsor
- University of North Carolina, Chapel Hill
Covid19, Sepsis
Blood Markers for Identifying & Investigating Infection With COVID19 & Sepsis in Children.
Corona Virus Disease or COVID-19 is caused by SARS-CoV-2 virus. There have been reports of serious COVID-19 illness in children. In addition it has been linked to clusters of children presenting with high fevers and inflammation.
- Trial name
- pSeP (NCT04904523)
- Testing
- Diagnostic Test:Blood test
- Where
- United Kingdom
- Volunteers
- 300 people
- Sponsor
- Cardiff University
Type 1 Diabetes, Eating Disorders
Multi-Site Eating Disorder Prevention Program for Type 1 Diabetes
This study aims to test the effectiveness of an evidence-based eating-disorder prevention program specifically targeted for individuals with Type 1 Diabetes (T1D) compared to an educational control group.
- Trial name
- NCT05399446
- Testing
- Diabetes Body Project, Educational Group
- Where
- 4 sites in United States, Netherlands and 1 more
- Volunteers
- 280 people
- Sponsor
- Oslo University Hospital
Thalassemia
Thalassemia Knowledge in Young People of Indonesia
There is still an ongoing lack of awareness about thalassemia among Indonesians despite high disease prevalence, and this is associated with poor implementation of preventive and promotive measures.
- Trial name
- NCT04706585
- Where
- Indonesia
- Volunteers
- 1,010 people, healthy volunteers welcome
- Sponsor
- Fakultas Kedokteran Universitas Indonesia