Clinical trials: Young Population
Insomnia, Chronic Pain
The Young Adult Clinic (YAC) Study
The overarching aim of the Young Adult Clinic (YAC) study is to evaluate the DOZE app, a digital, transdiagnostic behavioral sleep medicine and self-management approach in young adult patients (ages 18-25) with chronic pain.
- Conditions
- Insomnia, Chronic Pain, Insomnia Due to Medical Condition
- Trial name
- YAC (NCT05147974)
- Testing
- DOZE app
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Women's College Hospital
Endometrial Cancer
Treatment With Medroxyprogesterone Acetate Plus LNG-IUS in Young Women With Early Stage Endometrial Cancer
A prospective multicenter trial has been started in Korea to investigate the treatment efficacy of Levonorgestrel-releasing intrauterine system (LNG-IUS) plus Medroxyprogesterone Acetate(MPA) in Young Women with Early Stage…
- Trial name
- NCT01594879
- Testing
- MIrena(LNG-IUS), oral MPA
- Where
- South Korea
- Volunteers
- 39 people
- Sponsor
- Korean Gynecologic Oncology Group
Gonorrhoea
Mucosal Immunity Against Neisseria Gonorrhoeae After 4CMenB Vaccination
This is a Phase 2 mechanistic clinical trial to assess the systemic and mucosal immunogenicity of the multicomponent meningococcal serogroup B vaccine (4CMenB or Bexsero (R)) (group 1, 40 subjects) against Neisseria gonorrhoeae…
- Trial name
- NCT04722003
- Testing
- Meningococcal Group B Vaccine
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Dravet Syndrome, Seizure Disorder
A Trial of Two Fixed Doses of ZX008 (Fenfluramine HCl) in Children and Young Adults With Dravet Syndrome
Study 1 and Study 3 are the prospective, merged analyses of 2 identical double-blind, placebo-controlled studies, ZX008-1501 and ZX008-1502, to assess the efficacy, safety, and pharmacokinetics of ZX008 when used as adjunctive…
- Trial name
- NCT02682927
- Testing
- ZX008 (Fenfluramine Hydrochloride)
- Where
- 55 sites in United States, Australia and 9 more
- Volunteers
- 262 people
- Sponsor
- Zogenix International Limited, Inc., a subsidiary of Zogenix, Inc.
Cancer, Leukemia
Peer Support Group for Adolescent and Young Adult (AYA) Allogeneic Stem Cell Transplant Recipients
Allogeneic Haemopoietic Stem Cell Transplant (Allo-HSCT) is a potentially curative option for patients with both malignant and non-malignant hematological disorders.
- Conditions
- Cancer, Leukemia, Stem Cell Transplant
- Trial name
- NCT06704243
- Testing
- Peer Support
- Where
- Canada
- Volunteers
- 13 people
- Sponsor
- University Health Network, Toronto
Young Adult Behavioral Change
Text Message Stop Smoking Among Young Population
Smoking cessation is a priority for preventing smoking-attributable disease and reducing its burden. Quitting smoking at any age confers substantial and immediate health benefits, including reduced risks of stroke, cardiovascular…
- Trial name
- NCT02379325
- Testing
- Lets Quit, pamphlets material
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universiti Kebangsaan Malaysia Medical Centre
Gastrointestinal Mucositis, Malignant Neoplasm
Palifermin in Preventing Oral Mucositis Caused by Chemotherapy and/or Radiation Therapy in Young Patients Undergoing Stem Cell Transplant
This randomized phase II trial is studying palifermin to see how well it works compared with a placebo in preventing oral mucositis caused by chemotherapy and/or radiation therapy in young patients undergoing stem cell…
- Trial name
- NCT00728585
- Testing
- Palifermin
- Sponsor
- Children's Oncology Group
Type 1 Diabetes Mellitus
Efficacy and Safety of Sotagliflozin in Young Adult Patients With Type 1 Diabetes Mellitus and Elevated Hemoglobin A1C
This Phase 2 study was intended to demonstrate superiority of sotagliflozin versus placebo on Hemoglobin A1C (A1C) reduction at Week 12 in young adult participants with type 1 diabetes mellitus (T1DM) who have poor glycemic…
- Trial name
- NCT02383940
- Testing
- Sotagliflozin
- Where
- 15 sites in United States
- Volunteers
- 87 people
- Sponsor
- Lexicon Pharmaceuticals
Ethnic Group, Young Adults
Diabetes Prevention in Prediabetic Patients
This study will evaluate the feasibility and efficacy of two interventions of lifestyle ( intensive and less intensive) to prevent diabetes in patients from Ethiopian origin, aged 25 to 55 years old with prediabetes living in…
- Conditions
- Ethnic Group, Young Adults, Prediabetes, Community Health Services
- Trial name
- DPEP (NCT01659697)
- Testing
- intensive lifestyle counseling
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Meir Medical Center
Ageing, Blood Flow Restriction
Comparing Vascular Responses to Resistance Exercise with and Without Blood Flow Restriction in Young and Older Adults
Aging leads to declines in functional capacity and effort tolerance. Muscle strength remains stable from ages 25 to 50 but declines significantly after age 60, affecting activities like stair climbing and walking, reducing…
- Trial name
- HOLD TIGHT (NCT06596304)
- Testing
- Low intensity-resistance training with lower limb blood flow restriction, High Intensity Resistance Training
- Where
- 2 sites in Portugal
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Egas Moniz - Cooperativa de Ensino Superior, CRL
Population Health
The Young Adults' Experiences With Virtual Reality (YAES VR) Study
The purpose of this study is to test the effect of virtual reality (VR) food marketing exposure (versus VR non-food control) on snack consumption, purchase intention, hunger, and arousal in black and white young adults.
- Trial name
- NCT06917391
- Testing
- Wendyverse VR food marketing experience, Nikeland VR non-food marketing experience
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Obesity
Relative Risk of Hypertension Among Obese
Observational study was conducted to determine the relative risk of hypertension among young adult obese population of Pakistan with age between 25-40 years
- Trial name
- NCT04686513
- Testing
- Observation
- Where
- Pakistan
- Volunteers
- 1,149 people, healthy volunteers welcome
- Sponsor
- Ziauddin University
Iron Deficiency in Young Children Living in France
Iron Deficiency (ID) in Infants
ID in children is the most frequent micronutrient deficiency in industrialized countries, including France. ID induces neurological impairment reducing cognitive, motor, and behavioral capacities in children in the short and long…
- Trial name
- CARMA (NCT02484274)
- Testing
- Blood samples
- Where
- France
- Volunteers
- 830 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Depression, Interpersonal Relations
IPT-based Group Intervention by Non-specialist for Improvement of Depressive Symptoms in Community Young Adults in Brazil
Major depressive disorder is a highly prevalent, recurrent, and debilitating disease, the third cause of years of lost life in the world, and it may be the most common disease in 2030, according to the World Health Organization…
- Trial name
- NCT06480019
- Testing
- Interpersonal psychotherapy
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Autism Spectrum Disorder
Acceptability and Outcomes of an Online Parent-Mediated Intervention for Young Autistic Children
This preliminary single-arm pre-post interventional study was designed to evaluate the acceptability and preliminary clinical outcomes of an 8-week online group-based parent-mediated intervention (OYNA) for parents of young…
- Trial name
- NCT07763067
- Testing
- Online Group-Based Parent-Mediated Intervention (OYNA)
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people
- Sponsor
- Herguner Therapy Private Clinic
Hemiplegic Cerebral Palsy, Non-Accidental Traumatic Head Injury to Child
Intensive Group Based CIMT for Young Children
This project aims to investigate the effectiveness of an intensive, group-based Constraint Induced Movement Therapy (CIMT) program for young children ages 2-6 years with unilateral hemiparesis, or weakness on one side of the…
- Trial name
- NCT06330831
- Testing
- Intensive, Group Based Constraint Induced Therapy (CIMT)
- Volunteers
- 35 people
- Sponsor
- Rockhurst University
Ageing, Aerobic Exercise
Acute Exercise Effects on Arterial Stiffness and Cardiovagal Modulation in Adults
Background and Gap: The physiological importance of large artery distensibility in cardiovascular function is well-established. Stiffening of central arteries leads to elevated systolic blood pressure (SBP), increased left…
- Conditions
- Ageing, Aerobic Exercise, Resistance Exercise, Combined Exercise
- Trial name
- PUMPING ARTERY (NCT06616428)
- Testing
- Bike group fitness class, Pump Power, Global Training
- Where
- Portugal
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Egas Moniz - Cooperativa de Ensino Superior, CRL
Arousal
Influence of Arousal on Motor Learning, Memory and Motor Imagery Ability in Young Population
In motor learning is essential to consider that movements are produced by the cooperation and combination of many brain structures and are influenced by the emotions to which individuals are subjected.
- Trial name
- NCT04911439
- Testing
- Low Arousal, Medium arousal, High arousal
- Where
- 4 sites in France, Spain
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Susana Nunez Nagy
Parkinson's Disease (PD)
Empower Your Mind to Embrace Your Life: an Online ACT Intervention for Young-Onset Parkinson's Disease
Parkinson's disease (PD) has a substantial impact on daily life and significantly affects functioning, mental health and quality of life. Although considered a disease of the elderly, an early diagnosis is also common.
- Trial name
- NCT07310147
- Testing
- Empower your mind to embrace your life
- Where
- Portugal
- Volunteers
- 20 people
- Sponsor
- University of Coimbra
Invasive Group B Streptococcus Disease
Antibody Levels Associated With Reduced Risk of Invasive Group B Streptococcus Disease in Infants Aged Less Than 90 Days
Compare anticapsular antibody levels against Group B Streptococcus at delivery in mothers and their infants who develop disease versus those who do not.
- Trial name
- NCT02099149
- Where
- South Africa
- Volunteers
- healthy volunteers welcome
- Sponsor
- Novartis