Clinical trials: acne, open to volunteers
Acne Vulgaris
Study to Assess Safety, Pharmacokinetics, and Treatment Effect of Cabtreo
This study is to evaluate the safety, pharmacokinetics, and treatment effect for topically applied CABTREO lotion in pediatric participants ages 9 to 11 years, 11 months with Acne Vulgaris.
- Trial name
- NCT07524946
- Testing
- CABTREO is a fixed-combination product of clindamycin phosphate 1.2%/BPO 3.1%/adapalene 0.15%.
- Where
- 15 sites in United States
- Volunteers
- 100 people
- Sponsor
- Bausch Health Americas, Inc.
Acne Scars, Acne Scars - Atrophic
Safety and Efficacy Evaluation of the Radiofrequency Therapeutic Device for the Treatment of Atrophic Acne Scars
The objective of this clinical trial is to evaluate the safety and effectiveness of a radiofrequency treatment device for the treatment of atrophic acne scars.
- Conditions
- Acne Scars, Acne Scars - Atrophic, Acne Scar, Acne Scarring
- Trial name
- NCT07620769
- Testing
- Investigational Device with the function deactivated, Investigational Device with the function activated, Control Device
- Where
- 4 sites in China
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- CLASSYS Inc.
Acne Vulgaris, Acne Vulgaris on the Face
Study of New Antiandrogenic Progestogen + Low-dose Estrogen for Moderate Acne Vulgaris
This Phase III randomized, double-blind, placebo-controlled, adaptive, multicenter study evaluates the efficacy and safety of a new concentration of the fixed-dose combination EF190 in women with moderate acne vulgaris over six…
- Trial name
- PANDORA (NCT06905210)
- Testing
- Experimental drug (Cyproterone Acetate 2 mg and Ethinyl Estradiol 0.02 mg)
- Where
- 18 sites in Brazil
- Volunteers
- 531 people
- Sponsor
- Eurofarma Laboratorios S.A.
Acne
Phase 1 Study to Evaluate the Safety, Tolerability, PK, and PD of TVB-3567 in Healthy Participants With or Without Acne
This is a 4-part study. Part A will be a randomized, double-blind, placebo-controlled investigation of single ascending doses (SAD) to assess the safety, tolerability, pharmacokinetics (PK), and pharmacodynamic (PD) biomarkers of…
- Trial name
- NCT06989840
- Testing
- TVB-3567
- Where
- 6 sites in United States, Australia
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Sagimet Biosciences Inc.
Acne Vulgaris
1% Clascoterone Cream for the Treatment Acne Vulgaris
This is a multicenter, randomized, double-blind, parallel, placebo-controlled Phase III clinical study to evaluate the efficacy and safety of 1% Clascoterone Cream in the treatment of acne vulgaris.
- Trial name
- NCT07457294
- Testing
- 1% Clascoterone Cream
- Volunteers
- 692 people
- Sponsor
- Zhejiang Sunshine Mandi Pharmaceutical Co.,Ltd.
Acne
A Clinical Trial to Investigate the Efficacy and Safety of GenLabs' Social Renew on Improving Acne Symptoms and Skin Repair Among Healthy Adults
The goal of this interventional clinical trial is to investigate the efficacy and safety of GenLabs' Social Renew on improving acne symptoms and skin repair among healthy adults.
- Trial name
- NCT07127523
- Testing
- Social Renew
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- GenCanna Acquisition Corp
Acne Vulgaris on the Face
Efficacy and Tolerability of DispersinB Acne Cleanser in the Treatment of Mild to Moderate Acne Vulgaris
This is a single-center study using intra-individual comparison (right half-face versus left half-face) to evaluate the efficacy and tolerability of DispersinB Acne Cleanser for treatment of acne in adults.
- Trial name
- NCT06729450
- Testing
- DispersinB Acne Cleanser
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Kane Biotech Inc
Acne
Study to Evaluate Safety, Efficacy and Immunogenicity of Acne mRNA Vaccine in Adults With Moderate to Severe Acne
The purpose of the trial is to evaluate the safety, efficacy and immunogenicity of up to 3 intramuscular injections of the Acne mRNA vaccine candidate at up to four dose levels in adult participants aged 18 to 45 years with…
- Trial name
- NCT06316297
- Testing
- Acne mRNA vaccine
- Where
- 94 sites in United States, Australia and 2 more
- Volunteers
- 800 people
- Sponsor
- Sanofi Pasteur, a Sanofi Company
Acne
An Observational Clinical Study to Evaluate the Efficacy of the CeraVe Skin Care Line
This is an observational clinical study to evaluate the efficacy of the CeraVe Skin Care product line in improving mild to severe facial acne.
- Trial name
- NCT07044024
- Testing
- CeraVe
- Volunteers
- 240 people
- Sponsor
- ChinaNorm
Acne Vulgaris
Efficacy and Safety of Clascoterone Cream 1% in Facial Acne Vulgaris
The primary objective of this study is to determine the safety and efficacy of clascoterone cream, 1%, versus the vehicle cream applied twice daily for 12 weeks in subjects with facial acne vulgaris.
- Trial name
- NCT06403501
- Testing
- Clascoterone, Vehicle cream
- Where
- China
- Volunteers
- 692 people
- Sponsor
- Zhejiang Sunshine Mandi Pharmaceutical Co.,Ltd.
Acne
Exploring Acne Treatments Through Clinical Research Participation
The purpose of this study is to understand the lived experiences of acne patients enrolled in a related clinical trial testing a particular treatment.
- Trial name
- NCT07010458
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Power Life Sciences Inc.
Acne-prone Skin, Skin Disease
Observational Assessment of Skin Appearance Changes During PRX S Cosmetic Treatment in Participants With Acne-Prone Skin
This pilot cohort study evaluates changes in skin surface appearance in adult participants with acne-prone skin during and following a standardized five-session course of PRX S (WiQo SpA), a topical cosmetic product designed for…
- Trial name
- NCT07866131
- Testing
- PRX S topical cosmetic treatment, WiQo home care regimen (Nourishing Cream; Balancing Cream)
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- WiQo S.p.A.
Acne
Study to Evaluate Safety, Efficacy and Immunogenicity of Acne mRNA Vaccine in Participants With Mild Acne
The purpose of the VBE00009 study is to evaluate the safety, efficacy and immunogenicity of 2 administrations of the Acne mRNA vaccine candidate at single dose level in participants aged 18 to 45 years with mild acne.
- Trial name
- NCT07013747
- Testing
- Acne mRNA vaccine
- Where
- 4 sites in United States
- Volunteers
- 228 people
- Sponsor
- Sanofi Pasteur, a Sanofi Company
Acne Vulgaris
Comparing Sarecycline and Doxycycline Effects on the Skin and Gut Bacteria in Acne.
This study is being done to help better understand how the gut and skin bacteria of the body change when people with acne are treated with Sarecycline or Doxycycline.
- Trial name
- NCT07544251
- Testing
- Sarecycline, Doxycycline
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Integrative Skin Science and Research
Oily Skin, Acne Prone Skin
Dermal and Ophthalmological Acceptability and Comedogenicity Assessment of a Cosmetic Product
The goal of this clinical trial is to evaluate the dermatological and ophthalmological safety of a cosmetic product and to assess its comedogenic and acnegenic potential in participants with oily or acne-prone skin.
- Trial name
- NCT07848555
- Testing
- moisturizing cream
- Where
- Brazil
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Brainfarma Industria Química e Farmacêutica S/A
Dermatitis, Acne
PMCF Investigation of Medical Device ChitoCare® Medical
This is a post-marketing observational clinical investigation conducted as part of the post-market clinical follow-up of ChitoCare® Medical, aimed to confirm safety and efficacy according to the requirements of Regulation (EU)…
- Conditions
- Dermatitis, Acne, Conditions After Dematosurgical Procedures, Scars
- Trial name
- NCT06850389
- Testing
- ChitoCare® medical Wound Healing Gel, ChitoCare® medical Healing Spray
- Where
- 2 sites in Czechia
- Volunteers
- 214 people
- Sponsor
- Primex ehf
Acne, Acne Scars - Mixed Atrophic and Hypertrophic
AVAVA MIRIA General Use
A general protocol to treat a variety of dermatologic conditions and collect patient feedback. Primary outcome is the collection and analysis of patient questionnaires related to the overall experience of the device treatment.
- Conditions
- Acne, Acne Scars - Mixed Atrophic and Hypertrophic, Scars, Wrinkle
- Trial name
- NCT06868615
- Testing
- AVAVA
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- AVAVA, Inc.
Scars
Study to Evaluate the Efficacy of a Micro Coring Device for the Treatment of Scars of the Cytrellis Micro-Coring Device for the Treatment of Scars
A study to evaluate the safety and effectiveness of a micro coring device for the treatment of scars.
- Trial name
- NCT03782038
- Testing
- MCD
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cytrellis Biosystems, Inc.
Acne
Safety, Tolerability, and Clinical Effectiveness of Adapalene/Clindamycin Phosphate Gel (Klenzit®-C) in Vietnamese Patients With Mild to Moderate Acne Vulgaris
The CLEAN ACNE Study is a prospective, observational, Phase IV, open-label, multicenter, single-arm study at 3-5 sites in Vietnam.
- Trial name
- Clean Acne (NCT07918001)
- Testing
- Klenzit®-C (Adapalene/Clindamycin Phosphate Gel)
- Where
- 3 sites in Vietnam
- Volunteers
- 225 people
- Sponsor
- IR INNOVATE RESEARCH PRIVATE LIMITED
Acne Vulgaris
Phase 3 Study of Denifanstat in Participants With Moderate to Severe Acne (AURORA)
The purpose of this study is to evaluate the safety and efficacy of denifanstat compared with matching placebo in participants with moderate to severe acne vulgaris who are ≥12 years of age.
- Trial name
- NCT07863193
- Testing
- Denifanstat
- Where
- 28 sites in United States
- Volunteers
- 800 people
- Sponsor
- Sagimet Biosciences Inc.