Clinical trials: acne
Acne
Evaluation of Effaclar Duo+M on Acne Lesions in Subjects With Mild to Moderate Acne on Face and Trunk
This single-center, open, non-randomized study aims the efficacy evaluation of Effaclar Duo+M and Effaclar+M Purifying foaming gel on total acne lesion count, pigmented lesions and scars for 6 months in subjects with mild to…
- Trial name
- NCT06463925
- Testing
- acneic participants group
- Where
- Brazil
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Acne Vulgaris
Study of Trifarotene Cream to Assess Risk of a Trophic Acne Scar Formation
The purpose of this study is to evaluate the safety and efficacy of trifarotene 50 microgram per gram (mcg/g) cream compared to its vehicle on the risk of formation of atrophic acne scars after 24 weeks of treatment in facial…
- Trial name
- START (NCT04856904)
- Testing
- Trifarotene Cream, Trifarotene Vehicle Cream
- Where
- 18 sites in United States, Canada and 1 more
- Volunteers
- 121 people
- Sponsor
- Galderma R&D
Acne Vulgaris
Acne Remission Maintenance by Weekend Systemic Isotretinoin
The goal of this study is to learn if isotretinoin oral tablets as a weekend regimen are safe and effective to maintain freedom from acne lesions in young adults who have completed a full course of isotretinoin on daily basis and…
- Trial name
- NCT06451237
- Testing
- Isotretinoin capsules
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Alexandria University
Acne, Atopic Dermatitis
Use of the SpiderMass for in Vivo Analysis of the Skin in Five Chronic Inflammatory Dermatosis
The physiological states of the skin are characterized by a certain homeostasis linked to the balance of the metabolic pathways. When these pathways are deregulated, the proteic, lipidic and metabolic is affected.
- Conditions
- Acne, Atopic Dermatitis, Psoriasis Vulgaris, Rosacea
- Trial name
- NCT04472546
- Testing
- in-vivo mesure, Scotch, Lipid index
- Where
- France
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Pierre Fabre Dermo Cosmetique
Inflammatory Acne Vulgaris
Safety and Efficacy of Radio Frequency for the Treatment of Mild to Severe Inflammatory Acne
The aim of this trial is to evaluate the safety and efficacy of the InMode RF Pro System with the Morpheus8 face tip (24 pins) applicator for the treatment of mild, moderate and severe, facial acne vulgaris
- Trial name
- NCT05830968
- Testing
- Morpheus8 Applicator Radiofrequency device
- Where
- 4 sites in United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- InMode MD Ltd.
Acne Vulgaris, Gingivitis
Association of Acne Vulgaris With Oral Hygiene and Gingivitis
The goal of this observational study is to learn about in the relationship between acne vulgaris and oral hygiene and gingivitis.
- Conditions
- Acne Vulgaris, Gingivitis, Dental Plaque, Oral Hygiene
- Trial name
- NCT06237387
- Testing
- Periodontal examination
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Erzincan University
Acne Vulgaris, Folliculitis
Evaluation of Safety and Performance of Ialuxid Gel in Treatment of Acne Vulgaris, and Folliculitis
The Research Question of the present study is the following: in a population of men and women affected by acne vulgaris, and folliculitis, will Ialuxid® Gel (hydrogen peroxide, hyaluronic acid and glycine) improve the course of…
- Trial name
- NCT05345093
- Testing
- Ialuxid gel
- Where
- Romania
- Volunteers
- 66 people
- Sponsor
- BMG Pharma
Mild to Moderate Acne
Evaluation of the Safety and Efficacy of an Acne Treatment Device
A 50-patient study in which 400 microamps of direct current was applied 3 days per week. All tolerability, safety and efficacy endpoints were met.
- Trial name
- NCT06420804
- Testing
- ZIIP Acne Treatment Device
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- ZIIP Beauty
Acne
Single-Blind Study Assessing the Use of a Topical Antioxidant With A Series of Laser Procedures to Reduce Sebum Production
This is a split-face, single-blind study assessing the use of an antioxidant serum with a series of acne laser treatments to reduce sebum production in healthy male and female subjects between the ages of 18 and 65 years…
- Trial name
- NCT06376110
- Testing
- Topical Antioxidant Serum, AviClear Laser
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Austin Institute for Clinical Research
Acne Scars
Clinical Study to Evaluate Alexandrite Laser for the Treatment of Acne Scars
The intended use of the Alexandrite laser device used in this study is to assess the efficacy and safety of the Alexandrite laser device for the treatment of acne scars on skin types V and VI.
- Trial name
- NCT04807179
- Testing
- Experimental: RF Device Arm
- Where
- 2 sites in United States
- Volunteers
- 39 people
- Sponsor
- Cynosure, Inc.
Wrinkle, Fine Lines
Feasibility Study to Collect and Assess Safety Data for a Radiofrequency Microneedling Device for Electrocoagulation and Hemostasis of Soft Tissues for Dermatologic Conditions
The goal of the Potenza device used in this study is to collect clinical data for dermatologic conditions in which electrocoagulation and hemostasis is a viable mechanism for means of improvement.
- Conditions
- Wrinkle, Fine Lines, Crepey Skin, Acne Scars
- Trial name
- NCT05987319
- Testing
- RadioFrequency Microneedling Device
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Cynosure, Inc.
Cutibacterium Acnes Contamination
Wound Irrigation Comparative Effectiveness Study
The primary objective of this study is to compare the presence of C acnes in bacteriologic cultures taken from participant samples of subcutaneous and deep tissue prior to deep surgical irrigation using either Normal Saline…
- Trial name
- NCT06379919
- Testing
- Irrisept Irrigation, Saline Irrigation Solution Delivery
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Orthopaedic Education and Research Institute (dba Hoag Orthopedics)
Acne Vulgaris
Anti-microbial Role of Non-antibiotic Agents Against Cutibacterium Acnes in Patients With Acne Vulgaris
To evaluate and compare the anti-biofilm activity of Salicylic acid, Isotretinoin, and N-acetylcysteine against C. acne . To assess the possible role of Salicylic acid, Isotretinoin, and N-acetylcysteine in improving the…
- Trial name
- NCT06179056
- Testing
- assess the possible role of Salicylic acid, Isotretinoin, and N-acetylcysteine in improving the susceptibility of C. acne for Azithromycin and Doxycycline.
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Moderate to Severe Acne Vulgaris
Clinical Trial of Microneedle Radiofrequency Combined With Oral Isotretinoin in Moderate to Severe Acne
This study plans to select 100 AV patients and randomly divide them into two groups in a 1:1 ratio: the experimental group will be treated with MRF combined with oral isotretinoic acid for 8 consecutive weeks, with a total of 3…
- Trial name
- NCT06378983
- Testing
- Oral isotretinoin, Oral isotretinoin combined with microneedle radiofrequency therapy
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Acne Scars - Mixed Atrophic and Hypertrophic, Ice Pick Scars
Evaluation of Efficacy and Safety of HCC_45 for the Correction of Acne Scars of the Face
Acne scars represent a frequent complication of moderate/severe acne and may negatively impact on psychosocial and physical well-being of acne patients.
- Conditions
- Acne Scars - Mixed Atrophic and Hypertrophic, Ice Pick Scars, Rolling Scars, Boxcar Scars
- Trial name
- NCT05691049
- Testing
- HCC_45
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- IBSA Farmaceutici Italia Srl
Acne Vulgaris, Vitamin D Deficiency
Impact of COVID-19 Vaccination on Serum 25-hydroxyvitamin D Level
Vitamin D plays a pivotal but still not well understood role in the immune response to coronavirus disease (COVID-19) infection and vaccination.
- Conditions
- Acne Vulgaris, Vitamin D Deficiency, COVID-19
- Trial name
- NCT05398939
- Testing
- Blood test and skin evaluation
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- National Taiwan University Hospital
Acne Vulgaris
Study to Demonstrate the Efficacy and Safety of Adapalene/Benzoyl Peroxide Topical Gel in Subjects With Acne Vulgaris
This was a multi-center, randomized, double-blind, parallel group study with 12 weeks of treatment of acne vulgaris. Efficacy and safety evaluations were performed at Screening (safety only), Baseline and Weeks 1, 2, 4, 8 and 12.
- Trial name
- NCT00422240
- Testing
- Adapalene/Benzoyl Peroxide, Adapalene Gel, 0.1%, Benzoyl Peroxide Gel 2.5%
- Where
- United States
- Volunteers
- 1,668 people
- Sponsor
- Galderma R&D
Acne
Investigation of the Tolerability of Two Facial Cleansing Routines for Mild to Moderate Acne
The objective of this study is to compare tolerability of two similar commercially available over the counter acne regimens (Geologie and Proactiv) in individuals with mild to moderate acne vulgaris over a 12-week daily treatment…
- Trial name
- NCT05446402
- Testing
- Geologie Acne Regimen - one side of face, Proactive Acne Regimen - other side of face
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Northwestern University
Acne, Post Inflammatory Hyperpigmentation
LiftActiv B3 in Post Inflammatory Hyperpigmentation (PIHP)
The purpose of this research study is to measure the depigmenting effect of a serum product called Liftactiv B3 in patients with mild to moderate facial PIHP (Post Inflammatory Hyper Pigmentation)
- Trial name
- NCT05327361
- Testing
- Liftactiv B3, Sunscreen
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- University of Miami
Acne Vulgaris
Serum Intercellular Adhesion Molecule -1 in Acne Vulgaris Patients : Effect of Montelukast
The aim of this study is to: 1. Evaluation of serum soluble intercellular adhesion molecule-1 (sICAM-1) level in acne vulgaris and compare it to control group 2.
- Trial name
- NCT06340984
- Testing
- Montelukast 10 Mg Oral Tablet
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- South Valley University