Clinical trials: acne
Acne Vulgaris
Compare the Tolerance of Clindamycin 1% /Benzoyl Peroxide (BPO) 5% Gel to Clindamycin 1.2%/ BPO 2.5% Topical Medications
This is a single-blind (blinded expert grader) study that will enroll 25-30 healthy volunteers without facial acne. On 1 side of the face, the subject will apply 1 of the 2 test products, clindamycin and benzoyl peroxide 5% or…
- Trial name
- NCT01015638
- Testing
- Clindamycin and BPO 5% gel, Clindamycin phosphate and benzoyl peroxide 2.5% gel.
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Stiefel, a GSK Company
Sarcoidosis, Pulmonary, Sarcoidosis Skin
the PHENOSAR Trial: Use of Antibiotics in Treatment of Sarcoidosis
In this study it is investigated whether treatment with azithromycin in combination with doxycycline reduces the bacterial load of C.
- Trial name
- NCT05291468
- Testing
- FDG-PET/CT
- Where
- Netherlands
- Volunteers
- 40 people
- Sponsor
- St. Antonius Hospital
Acne
Study of the Use of Low Level Laser Therapy to Reduce Acne
The purpose of this study is to determine whether low level laser light therapy is effective in the treatment of acne blemishes.
- Trial name
- NCT01276535
- Testing
- Erchonia MLS + Erchonia THL
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Erchonia Corporation
Inflammatory Acne Vulgaris
Safety and Efficacy of Radio Frequency for the Treatment of Mild to Severe Inflammatory Acne
The aim of this trial is to evaluate the safety and efficacy of the InMode RF Pro System with the Morpheus8 face tip (24 pins) applicator for the treatment of mild, moderate and severe, facial acne vulgaris
- Trial name
- NCT05830968
- Testing
- Morpheus8 Applicator Radiofrequency device
- Where
- 4 sites in United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- InMode MD Ltd.
Acne Vulgaris
Cutaneous Tolerability and Safety of NVN1000 Topical Gel in Healthy Volunteers
The study will assess safety and tolerability of different doses of topical gel containing a new chemical entity, NVN1000, and the vehicle (gel without drug) applied to the face of healthy volunteers with high counts of…
- Trial name
- NCT01694810
- Testing
- 2% NVN1000 Topical Gel, 4% NVN1000 Topical Gel, 8% NVN1000 Topical Gel
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Novan, Inc.
Acne Vulgaris, Acne Vulgaris on the Face
Study of New Antiandrogenic Progestogen + Low-dose Estrogen for Moderate Acne Vulgaris
This Phase III randomized, double-blind, placebo-controlled, adaptive, multicenter study evaluates the efficacy and safety of a new concentration of the fixed-dose combination EF190 in women with moderate acne vulgaris over six…
- Trial name
- PANDORA (NCT06905210)
- Testing
- Experimental drug (Cyproterone Acetate 2 mg and Ethinyl Estradiol 0.02 mg)
- Where
- 18 sites in Brazil
- Volunteers
- 531 people
- Sponsor
- Eurofarma Laboratorios S.A.
Acne Vulgaris
A Study to Evaluate the Reduction in Sebum (Skin Oil) Induced by Clascoterone Cream 1% in Acne Patients
The etiology of acne is heavily dependent on the production of sebum by the sebaceous glands that results in the growth of the bacteria c. acnes. If no sebum is present, there is no nutritional source for the c.
- Trial name
- NCT06415279
- Testing
- Winlevi (clascoterone) 1% cream
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Sun Pharmaceutical Industries Limited
ACNE SCARRING
A Pilot Study to Determine Safety & Efficacy of Autologous Human Platelet Lysate (HPL) in Treatment of Acne Scarring
This is a multicentre, open label, randomized, pilot study to evaluate safety and efficacy of Human Platelet Lysate (HPL) in subjects with Acne Scarring. The study is being conducted at 2 centers in India.
- Trial name
- NCT01644435
- Testing
- Autologous Human Platelet Lysate
- Where
- India
- Volunteers
- 19 people
- Sponsor
- Kasiak Research Pvt. Ltd.
Hidradenitis Suppurativa
Hidradenitis Suppurativa Mail Survey
Hidradenitis Suppurativa (HS), also known as "acne inversa," is a chronic dermatologic disease affecting apocrine gland-bearing areas and presenting with symptoms ranging from pustules and inflammatory nodules to draining…
- Trial name
- NCT03572738
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- Wake Forest University Health Sciences
Acne
The Benefit of a Deep Cleansing Gel in the Management of Mild to Moderate Truncal Acne
Acne vulgaris is a chronic inflammatory disease, mainly of the face, but also of the trunk. Acne may be caused by internal and external factors. Only a very small amount of data exists concerning truncal acne.
- Trial name
- NCT05584150
- Testing
- Deep Cleansing Gel
- Where
- Brazil
- Volunteers
- 35 people
- Sponsor
- Cosmetique Active International
Acne, Wrinkle
Fractional Radiofrequency for Treatment of Acne Scars and Wrinkles
This study will evaluate the clinical efficacy, safety and the performance of the fractional radiofrequency delivered by the BTL-585-4 applicator of the BTL-585F system for non-invasive treatment of acne scars and facial…
- Trial name
- NCT05827510
- Testing
- BTL-585F
- Where
- 2 sites in United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- BTL Industries Ltd.
Acne Vulgaris
A Study Comparing Tretinoin Cream 0.025% and RETIN-A® Cream 0.025% in the Treatment of Acne Vulgaris
The bioequivalence and safety of Tretinoin Cream 0.025% (Taro Pharmaceuticals U.S.A, Inc.) and RETIN-A® (Tretinoin) Cream 0.025% in the treatment of acne vulgaris.
- Trial name
- NCT04724473
- Testing
- Tretinoin Cream 0.025%
- Where
- United States
- Volunteers
- 1,030 people, healthy volunteers welcome
- Sponsor
- Sun Pharmaceutical Industries, Inc.
Atrophic Acne Scar
Efficacy of Intralesional Injection of Pentoxifylline, Platelet-Rich Plasma, and Combined Pentoxifylline With Platelet-Rich Plasma in Patients With Atrophic Acne Scars
Platelet-rich plasma (PRP) is an Acne vulgaris is a common chronic inflammatory skin disorder. It is the eighth most prevalent disease worldwide with a prevalence of 9.4%.
- Trial name
- NCT06319768
- Testing
- Pentoxifylline, platelet rich plasma, combined pentoxifylline and platelet rich plasma
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Sohag University
Acne Vulgaris
A Study Comparing Clindamycin Phosphate, Adapalene, and Benzoyl Peroxide Topical Gel 0.15%;3.1%;1.2% (Taro Pharmaceuticals U.S.A., Inc.) and CABTREO Topical Gel for the Treatment of Acne Vulgaris.
To demonstrate the efficacy, therapeutic equivalence and safety of Clindamycin Phosphate, Adapalene, and Benzoyl Peroxide Topical Gel 0.15%;3.1%;1.2% (Taro Pharmaceuticals U.S.A., Inc.) and CABTREO Topical Gel in the treatment of…
- Trial name
- NCT06673641
- Testing
- Clindamycin Phosphate, Adapalene, and Benzoyl Peroxide Topical Gel 0.15%;3.1%;1.2%, CABTREO Topical Gel
- Where
- United States
- Volunteers
- 382 people, healthy volunteers welcome
- Sponsor
- Sun Pharmaceutical Industries, Inc.
Acne
Topical Application of Engineered Lactobacillus Reuteri With a Zinc Sulfate-Tannic Acid MPN Coating for Acne
A growing body of evidence suggests that the development and progression of acne are closely linked to an imbalance in the skin's microbial community.
- Trial name
- NCT07366229
- Testing
- MPN-coated engineered Lactobacillus reuteri cream, Plain Lactobacillus reuteri cream, Petrolatum-glycerin cream
- Where
- China
- Volunteers
- 196 people
- Sponsor
- Shenzhen People's Hospital
Acne
Use of Mobile Teledermatology in the Care of Acne Patients
The purpose of the present study is to determine whether a mobile teledermatology care model can achieve better clinical outcomes as compared to conventional, outpatient care for the management of severe acne treated with…
- Trial name
- Teleacne (NCT01399970)
- Testing
- Mobile Teleconsultation Arm (MTA), Outpatient Consultation Arm (OCA)
- Where
- Austria
- Volunteers
- 69 people
- Sponsor
- Medical University of Graz
Propionibacterium Infection
Antimicrobial Prophylaxis for Skin Colonization With Propionibacterium Acnes in Primary Open Shoulder Surgery
INESS Antibiotic Prophylaxis in Orthopedic Guide recommends the use of Cefazolin at induction for all orthopaedic procedure with implantation of internal fixation device. With the increasing rate of identified P.
- Trial name
- PAPA (NCT02996656)
- Testing
- Cefazolin, Ceftriaxone
- Where
- Canada
- Volunteers
- 88 people
- Sponsor
- Université de Montréal
Acne Vulgaris
Effect of Oral Isotretinoin on The Level of SerumYKL40 in Acne Vulgaris Patients
The aim of the study is to evaluate the effect of oral isotretinoin on SerumYKL40 in acne vulgaris patients.
- Trial name
- NCT05218486
- Testing
- Isotretinoin
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Alshimaa Abbas Mohamed Ebrahim
Acne Vulgaris
5% Sodium L-Ascorbyl-2-Phosphate Lotion for the Treatment of Acne Vulgaris
12-week study to compare the efficacy and safety of a course of a twice daily treatment with APS in the form of a lotion to its vehicle for the treatment of acne.
- Trial name
- NCT00714454
- Testing
- APS Topical Lotion
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Miami
Atrophic Acne Scarring
The Use of Bellafill for Atrophic Acne Scar Correction in the Full Facial Area
This is an open-label, multicenter, prospective pilot study assessing the efficacy and safety of Bellafill for correction of distensible atrophic acne scars in the full facial area.
- Trial name
- NCT02642627
- Testing
- Bellafill
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Suneva Medical, Inc.
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