Clinical trials: acne
Acne Vulgaris
Efficacy and Safety Study of 2 Different Concentrations of CD1579 Gels Versus Vehicle in the Treatment of Acne Vulgaris.
This study is to assess the efficacy and safety of two concentrations of CD1579 (2.5% and 5%) versus vehicle in the treatment of acne vulgaris in the Japanese patients.
- Trial name
- NCT02073461
- Testing
- CD1579 2.5%, CD1579 5%, Vehicle
- Where
- 6 sites in Japan
- Volunteers
- 236 people
- Sponsor
- Galderma R&D
Acne
Efficacy of Cosmetic Product RV3278B-OS0386 on Skin Surface Ecosystem, in Teenagers with Mild to Moderate Facial Acne
The aim of this exploratory study is to better understand the mechanisms of action of the RV3278B-OS0386 cosmetic product on the cutaneous ecosystem, in acne context.
- Trial name
- NCT06659861
- Testing
- RV3278B-OS0386, RV4632A-RY1845
- Where
- Romania
- Volunteers
- 52 people
- Sponsor
- Pierre Fabre Dermo Cosmetique
Acne Vulgaris
Risk Minimisation Study for Diane-35 and Its Generics
The study will be an observational, cross-sectional study of knowledge, understanding, and self-reported behavior among a sample of physicians with recent experience in prescribing Diane-35 or its generics in a total of five…
- Trial name
- NCT02410031
- Testing
- Cyproterone acetate 2mg/ethinylestradiol 35 μg (Diane-35)
- Where
- 5 sites in Austria, Czechia and 3 more
- Volunteers
- 759 people
- Sponsor
- Bayer
Acne Vulgaris
Effect of a Low-glycemic-load and Milk-free Diet on Acne Severity
The objective of this study is to assess the effect of a low-glycemic-load and milk-free diet on acne severity. IGF-1 and a phosphorylated product of the mTORC pathway (p70S6K) will be assessed in both groups to explore the mTORC…
- Trial name
- NCT01969175
- Testing
- Low-glycemic-load and milk-free diet
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Parc Taulí Hospital Universitari
Acne Vulgaris
1% Clascoterone Cream for the Treatment Acne Vulgaris
This is a multicenter, randomized, double-blind, parallel, placebo-controlled Phase III clinical study to evaluate the efficacy and safety of 1% Clascoterone Cream in the treatment of acne vulgaris.
- Trial name
- NCT07457294
- Testing
- 1% Clascoterone Cream
- Volunteers
- 692 people
- Sponsor
- Zhejiang Sunshine Mandi Pharmaceutical Co.,Ltd.
Acne Vulgaris
Study Comparing Adapalene/BP Gel to EPIDUO® FORTE and Both to a Placebo Control in Treatment of Acne Vulgaris
Bioequivalence with Clinical Endpoints.
- Trial name
- NCT02709902
- Testing
- Adapalene/BP gel, 0.3%/2.5%, EPIDUO® FORTE
- Volunteers
- 460 people
- Sponsor
- Sun Pharmaceutical Industries, Inc.
Acne Vulgaris
Aczone Gel 7.5% in the Treatment of Acne Vulgaris in Patients With Skin of Color
Acne vulgaris is a common skin disease characterized by inflammatory papules, pustules, and comedones that is prevalent in men and women of color.
- Trial name
- NCT03681470
- Testing
- Aczone Gel
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Acne
Efficacy and Safety of Aczone 7.5% Gel in the Treatment of Truncal Acne Vulgaris
To determine if Dapsone (Aczone) 7.5% gel is a safe and effective treatment for acne on the trunk
- Trial name
- NCT02944461
- Testing
- Dapsone 7.5 % gel
- Where
- 3 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Derm Research, PLLC
Acne Vulgaris
A Study Evaluating the Efficacy and Safety of Clascoterone Cream 1% in Skin of Color Patients With Acne
Acne vulgaris is the most common skin disease in patients with skin of color and second most common in Caucasian population. The global prevalence is thought to be as high as 60-80% in individuals 12-25 years of age.
- Trial name
- NCT06415305
- Testing
- Winlevi (clascoterone) 1% cream
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Sun Pharmaceutical Industries Limited
Acne Vulgaris
Dry Eye Disease With Isotretinoin ISOTRETINOIN
The study aims to explore the effects of isotretinoin therapy on the dry eye parameters in acne vulgaris patients \& determine if it is dose-dependent or not.
- Trial name
- NCT06725290
- Testing
- Ocular Surface Disease Index (OSDI) questionnaire
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Acne Vulgaris
Measure the Serum Level of Homocysteine in Acne Patients Before and After Oral Isotretinoin.
Serum homocysteine level in Acne patients before and after oral Isotretinoin and Correlation between serum level of homocysteine in acne patients before and after Oral isotretinoin treatment
- Trial name
- NCT05529888
- Testing
- Isotretinoin
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Aswan University
Acne Vulgaris
Effectivity and Safety of Combination of Spent Grain Wax, Argan Oil, Shea Butter and Saccharide Isomerate
The clinical study will compare the efficacy and safety of Combination of Spent Grain Wax, Argan Oil, Shea Butter and Saccharide Isomerate cream post fractional CO2 laser.
- Trial name
- NCT05186246
- Testing
- Combination cream
- Where
- Indonesia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Dr.dr.Irma Bernadette, SpKK (K)
Acne
Pilot Study of a Dietary Intervention to Prevent Acne Recurrence
The purpose of this study is to determine whether minimizing the intake of milk and dairy products will reduce the recurrence of acne among people who have been successfully treated for acne with isotretinoin.
- Trial name
- NCT00132574
- Testing
- Minimization of milk and dairy products in the diet
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Harvard School of Public Health (HSPH)
Acne Vulgaris
W0265-103: A Single-Center, Evaluator-Blinded, Randomized, Placebo Controlled, Phase 1 Clinical Trial Evaluating The Phototoxic Potential Of Topically Applied Clindamycin 1.0% - Tretinoin 0.025% Gel (Ct Gel) In Healthy Volunteers
Clindamycin 1.0% - tretinoin 0.025% gel (CT Gel) is a reformulation of VELAC Gel that contains the same active ingredients (clindamycin 1.0% and tretinoin 0.025%) in a modified vehicle.
- Trial name
- NCT01929278
- Testing
- CT Gel (clindamycin 1% and tretinoin 0.025%), Vehicle gel patch, Blank patch
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Stiefel, a GSK Company
Acne
Adapalene BPO Gel Pump, Moisturizer SPF 30 and Foam Wash in Patients With Mild to Moderate Acne Vulgaris
This is an open-label, multi-center study to be conducted in the United States. The study will examine the change in lesion count in subjects using Epiduo® Gel Pump (once daily) in conjunction with Cetaphil® DermaControl™ Foam…
- Trial name
- NCT01951417
- Testing
- Adapalene/BPO Gel, Moisturizer SPF 30, Foam Wash
- Where
- 5 sites in United States
- Volunteers
- 81 people
- Sponsor
- Galderma R&D
Acne Vulgaris
Infrared Non-Cutting Laser Therapy for Acne
The purpose of this research project is to study the effect of non-ablative (non-cutting) laser therapy, a technique that uses laser energy to try to improve the appearance of the skin.
- Trial name
- NCT00110643
- Testing
- CoolTouch II laser
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Michigan
Acne Vulgaris, Acne
Skin Hydration in Persons With Acne After Dietary Supplementation With Botanical Antioxidants
Antioxidants have been studied for their abilities to combat reactive oxygen species in a multitude of conditions. This study aims to assess whether the botanical dietary supplement 'Halo Beauty Kiwi Booster' (HBKB), taken orally…
- Trial name
- KIWIBOOSTER (NCT04534140)
- Testing
- HBKB Capsule, HBKB Supplement Vehicle
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Acne Vulgaris
"Clinical Trial to Determine the Efficacy of Vitamin D for Acne Therapy"
The purpose of this study is to study the effects of topical Vitamin D cream (Calcipotriene, also known as Dovonex) on acne. The information gained from this study may lead to new treatments for acne.
- Trial name
- NCT01694433
- Testing
- Calcipotriene
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Acne Vulgaris
Study to Evaluate the Safety and Efficacy of ASC40 in Subjects With Moderate to Severe Acne Vulgaris
This is a phase2, randomized, double-blind, multi-center, multi-dose and placebo parallel controlled design. The subjects in the study group were given double-blind drugs, and they were taken (orally) after dinner every day…
- Trial name
- NCT05104125
- Testing
- ASC40 25mg, ASC40 50mg, ASC40 75mg
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Ascletis Pharmaceuticals Co., Ltd.
Atrophic Acne Scars
A Pilot Study to Evaluate the Safety and Effectiveness of Microneedling and Bellafill to Treat Facial Acne Scars
This is an open-label, randomized, multicenter, prospective trial assessing the efficacy and safety of microneedling treatment alone vs.
- Trial name
- NCT02643628
- Testing
- Microneedling, Microneedling followed by Bellafill treatment
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Suneva Medical, Inc.
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