Clinical trials: acne
Acne Vulgaris
To Evaluate the Therapeutic Equivalence and Safety of TRETINOIN CREAM, 0.1% and RLD in the Treatment of Acne Vulgaris
Bioequivalence study comparing Tretinoin Cream, 0.1% to RETIN-A®.
- Trial name
- NCT03427554
- Testing
- Tretinoin cream 0.1%, RETIN-A® Cream, Vehicle of the test product
- Where
- United States
- Volunteers
- 455 people, healthy volunteers welcome
- Sponsor
- Sun Pharmaceutical Industries, Inc.
Acne Vulgaris
A Study to Determine Bioequivalence of Isotretinoin in Healthy Male Subjects Under Fed Condition
This is an open-label, crossover, randomized, single dose, three treatments, three periods and six sequences, single dosage, balanced study to determine Bioequivalence of Isotretinoin.
- Trial name
- NCT02498288
- Testing
- Isotretinoin: Reference Medication 1, Isotretinoin: Reference Medication 2, Isotretinoin: Test Medication
- Where
- Mexico
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Acne Vulgaris
TSN2898-201 Safety and Efficacy of TSN2898 in the Treatment of Acne Vulgaris
The purpose of this study is to determine the safety and effectiveness of TSN 2898 topical gel in the treatment of moderate to severe acne.
- Trial name
- NCT02796066
- Testing
- Vehicle, TSN2898
- Where
- 6 sites in United States, Dominican Republic and 1 more
- Volunteers
- healthy volunteers welcome
- Sponsor
- Thesan Pharmaceuticals, Inc.
ATROPHIC ACNE SCARS
Comparison Of Outcome Of Microneedling With Autologous PRP Vs Microneedling With Topical Insulin In Treatment Of Post Acne Atrophic Scars.
Microneedling with topical INSULIN is a simple, effective tool for building body's new collagen layers and thus an alternative to all erosive techniques such as lasers, peels.
- Trial name
- NCT06002854
- Testing
- PRP( platelet rich plasma) and Insulin human
- Where
- Pakistan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Jinnah Postgraduate Medical Centre
Hidradenitis Suppurativa
Evaluation of Sonelokimab for the Treatment of Patients With Active Moderate to Severe Hidradenitis Suppurativa
This is a study to demonstrate the clinical efficacy and safety of the nanobody® sonelokimab administered subcutaneously (sc) compared with placebo in the treatment of adult participants with moderate to severe hidradenitis…
- Trial name
- NCT05322473
- Testing
- Sonelokimab (M1095), Adalimumab
- Where
- 57 sites in United States, Bulgaria and 5 more
- Volunteers
- 234 people
- Sponsor
- MoonLake Immunotherapeutics AG
Acne Vulgaris
Study to Determine Efficacy, Safety, and Tolerability of B244 as a Topical Spray in Subjects With Moderate to Severe Acne Vulgaris
This is a phase 2b, randomized, double-blind, vehicle-controlled clinical trial evaluating the efficacy, safety, and tolerability of B244 compared to vehicle in the treatment of moderate to severe acne vulgaris in adolescents and…
- Trial name
- NCT07866105
- Testing
- B244, Vehicle
- Volunteers
- 176 people
- Sponsor
- AOBiome LLC
Acne Vulgaris
Evaluation of Efficacy and Tolerance of Crystal Peel in the Treatment of Adults Presenting Facial Mild Acne
The goal of this interventional, confirmatory and post market study is to evaluate the efficacy and clinical performance of Crystal Peel in adults suffering mild facial acne vulgaris.
- Trial name
- NCT05821296
- Testing
- Crystal Peel
- Where
- Poland
- Volunteers
- 42 people
- Sponsor
- Dermosciences France
Cicatrix
A Pilot Study Testing Fractional Radiofrequency Versus Fractional Photothermolysis for the Treatment of Acne Scars
The purpose of this study is to compare the effectiveness of the ePrime fractional radiofrequency system to the 1550-nm fractional photothermolysis system (Fraxel) in the ability to improve acne scar appearance.
- Trial name
- NCT01976260
- Testing
- Fractional Radiofrequency, 1550-nm Fractional Photothermolysis
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Post-acne Erythema
Comparison of the Efficacy and Safety of Delicate Pulsed Light and Q-Switched 1064 nm Nd:YAG Laser in the Treatment of Post-Acne Erythema
Acne vulgaris is a common chronic dermatological condition, affecting approximately 85% of adolescents worldwide and ranking eighth among all chronic diseases.
- Trial name
- NCT06998589
- Testing
- DPL
- Where
- China
- Volunteers
- 26 people
- Sponsor
- Second Affiliated Hospital of Xi'an Jiaotong University
Acne Vulgaris
Knowledge Evaluation and Assessment of the Effectiveness of an Education Intervention on Acne
Acne vulgaris is a chronic inflammatory disorder of the skin in the pilosebaceous unit of the hair follicle, associated with oil production.
- Trial name
- NCT01629797
- Testing
- Educational script on Acne
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Northwestern University
Wrinkles, Fine Lines
Feasibility Study To Collect Safety And Preliminary Efficacy Data For A Radiofrequency Microneedling Device
The intended use of the Potenza™ device is to collect clinical data for brow lifting and/or treatment of dermatologic conditions in which electrocoagulation and hemostasis is a viable mechanism for means of improvement.
- Conditions
- Wrinkles, Fine Lines, Crepey Skin, Acne Scars
- Trial name
- NCT05254210
- Testing
- RF Device (Potenza™)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Cynosure, Inc.
Shoulder Infections
Acne crème to Reduce Propionibacterium Acnes Load in Primary Shoulder Surgery
60 patients undergoing first time open shoulder surgery (Latarjet, prosthesis) will be prospectively included in this study. The investigators will do a randomized controlled trial, choosing with a single-blinded protocol 30…
- Trial name
- NCT03949751
- Testing
- Acne Crème Plus
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- Balgrist University Hospital
Acne
An Open Label Trial to Assess the Safety and Efficacy of Oral R115866 in the Treatment Facial Acne
This study is looking at a new oral drug to treat acne. All patients in the study will get active drug, there is no placebo arm.
- Trial name
- NCT00725439
- Testing
- Talarozole
- Where
- 3 sites in Belgium, Netherlands
- Volunteers
- 16 people
- Sponsor
- Stiefel, a GSK Company
Acne
Safety & Effectiveness of the BEAM Device in Mild-to-moderate Acne
This study will determine if the use of the BEAM device reduces the signs and symptoms of mild-to-moderate acne.
- Trial name
- NCT01162837
- Testing
- BEAM device
- Where
- 3 sites in United States
- Volunteers
- 33 people
- Sponsor
- Oregon Aesthetic Technologies
Acne Vulgaris
A Phase 1 Study Evaluating Safety and Tolerability of NVN1000 Gel
This is a 2 week Phase 1 study of SB204 (NVN1000 Gel) in healthy adult volunteers with elevated Propionibacterium acnes (P. acnes) counts. Subjects will apply NVN1000 4% Gel or Vehicle Gel twice daily to their face.
- Trial name
- NCT01844739
- Testing
- NVN1000 4% Gel, Vehicle Gel
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Novan, Inc.
Acne Vulgaris
A Phase 4, Single-Blind, Randomized, Study to Compare the Tolerability and Efficacy of 0.1% Tazorac Cream When Used in Combination With Either Duac Gel or Acanya Gel for the Treatment of Facial Acne Vulgaris
A single-blind (investigator-blinded), randomized, parallel group, single center study to evaluate the tolerability and efficacy of combination therapy with Duac Gel / 0.1% Tazorac Cream and Acanya Gel / 0.1% Tazorac Cream for…
- Trial name
- C0000-411 (NCT01016977)
- Testing
- Clindamycin 1%/Benzoyl Peroxide 5% and 0.1% tazarotene, clindamycin phosphate 1.2%/benzoyl peroxide 2.5% and 0.1% tazarotene
- Volunteers
- 40 people
- Sponsor
- Stiefel, a GSK Company
Acne Vulgaris, Post Inflammatory Hyperpigmentation
Tazarotene 0.045% Lotion for Treating PIE and PIH in Subjects With Acne
The purpose of the study is to assess the safety and efficacy of Arazlo Lotion (Tazarotene 0.045% Lotion) for treatment of postinflammatory erythema and postinflammatory hyperpigmentation in subjects with acne.
- Conditions
- Acne Vulgaris, Post Inflammatory Hyperpigmentation, Post Inflammatory Pigmentation Change, Erythema
- Trial name
- NCT05704114
- Testing
- Tazarotene 0.045% Lotion
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Dr. Emmy Graber
Acne Vulgaris
Assessment of Subjects' Efficacy and Experiences Using Adapalene BPO Gel in the Treatment of Acne Vulgaris
The purpose of this study is to assess subjects' experiences using Adapalene BPO gel to treat mild to moderate acne vulgaris using efficacy measurements, quality of life instruments, and video diaries.
- Trial name
- NCT01209949
- Testing
- Adapalene 0.1% and Benzoyl Peroxide 2.5% gel
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Galderma R&D
Acne Lesion Counts
The Effect of「GTT-EGCG」on Acne Women
The aim of this study is to investigate the therapeutic effects of green tea extract on acne treatment and related hormone peptides by a double-blinded, randomized and controlled clinical trial.
- Trial name
- NCT01846338
- Testing
- green tea extract EGCG
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Acne Vulgaris
Phase 3 Study of Denifanstat in Participants With Moderate to Severe Acne (AURORA)
The purpose of this study is to evaluate the safety and efficacy of denifanstat compared with matching placebo in participants with moderate to severe acne vulgaris who are ≥12 years of age.
- Trial name
- NCT07863193
- Testing
- Denifanstat
- Where
- 28 sites in United States
- Volunteers
- 800 people
- Sponsor
- Sagimet Biosciences Inc.
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