Clinical trials: acne
Atrophic Acne Scar, Atrophic Acne Scarring
To Compare the Efficacy of Intralesional Saline Versus 35% Trichloracetic Acid (TCA) Peel in the Treatment of Atrophic Acne Scars
This study aimed to compare the efficacy of intradermal normal saline versus trichloroacetic acid (TCA) in treating atrophic acne scars.
- Trial name
- NCT06789874
- Testing
- Intralesional Saline, 35% trichloracetic acid peel
- Where
- 2 sites in Pakistan
- Volunteers
- 126 people
- Sponsor
- Sheikh Zayed Medical College
Acne
Clinical Efficacy Evaluation of a Skincare Product for Acne Face, Upper Chest and Back Used by Multiphototype Population Under Dermatological Control
The present aims to confirm, under normal conditions of use, the IP's clinical efficacy in controlling acne on the face, upper chest, and back after 28 and 42 days of product use, as well as illustrate its efficacy through…
- Trial name
- NCT06786442
- Testing
- EFFACLAR DUO+M CREAM
- Where
- Brazil
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Acne, Acne Vulgaris
A Pilot Study to Explore the Role of Gut Flora in Acne
This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records.
- Conditions
- Acne, Acne Vulgaris, Acne Keloidalis, Acne Keloid
- Trial name
- NCT04214483
- Testing
- No intervention
- Where
- United States
- Sponsor
- ProgenaBiome
Post Inflammtory Erythema, Acne Vulgaris
Efficacy of 0.5% Topical Timolol Eye Drops in the Treatment of Post-Inflammatory Erythema Following Acne Vulgaris
Post-inflammatory erythema (PIE) is a common sequela of acne vulgaris, characterized by persistent erythematous macules resulting from superficial vascular dilation.
- Conditions
- Post Inflammtory Erythema, Acne Vulgaris, Erythema
- Trial name
- NCT07474883
- Testing
- Timolol 0.5% Ophthalmic Solution, Intense Pulsed Light
- Where
- Vietnam
- Volunteers
- 60 people
- Sponsor
- Pham Ngoc Thach University of Medicine
Acne Vulgaris
Studying the Skin Microbiome and the Potential of a Topical Probiotic Cream for Patients With Acne
In this study the topical use of cream with live probiotic bacteria was evaluated for its efficacy in reducing acne symptoms and its effect on the skin microbiota on patients with acne.
- Trial name
- NCT03469076
- Testing
- YUN ACN Cream
- Where
- Belgium
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Acne Vulgaris, Atrophic Acne Scar
Autologous Plasma Gel Injection Versus Polydioxanone Cog Threads Insertion for the Treatment of Atrophic Post-acne Scars: a Split-face
Both male and female patients, with atrophic acne scars All patients underwent one session of subcision before receiving: A: cog PDO threads on one side of the face (one session). B: plasma gel on the other side (one session).
- Trial name
- NCT06580691
- Testing
- Subcision plus Plasma gel injection Vs Subcision plus Cog PDO threads
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Sameh Sarsik
Acne Vulgaris
Pulsed Dye Laser Treatment of Acne Vulgaris
The results of pulsed dye laser (PDL) treatment of acne vulgaris published so far are controversial: Whereas Seaton et al. described a marked improvement of mild-to-moderate acne after low-fluence pulsed-dye laser therapy…
- Trial name
- NCT01052246
- Testing
- Fixed combination of clindamycin 1% + benzoyl peroxide 5%, Pulsed dye laser
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- Laserklinik Karlsruhe
Acne Scars - Mixed Atrophic and Hypertrophic, Wrinkle
Fractional Radiofrequency for the Treatment and Reduction of Acne Scars and Wrinkles
The objective of this clinical study is to evaluate the efficacy of fractional RF for the treatment and reduction of acne scarring or facial wrinkles.
- Trial name
- NCT04057768
- Testing
- Venus Viva
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Venus Concept
Pustular Psoriasis (PP), Generalized Pustular Psoriasis (GPP)
Evaluating Legit.Health Plus Support for Improving Diagnosis of Generalized Pustular Psoriasis and Other Skin Conditions Among Primary Care Physicians and Dermatologists
This study aims to determine if an artificial intelligence (AI) medical device can help healthcare professionals more accurately diagnose rare and complex skin conditions.
- Conditions
- Pustular Psoriasis (PP), Generalized Pustular Psoriasis (GPP), Eczema Atopic Dermatitis, Acute Generalized Exanthematous Pustulosis
- Trial name
- LegitHealth BI (NCT07428915)
- Testing
- AI-based medical device for aided diagnosis in Dermatology
- Where
- Spain
- Volunteers
- 15 people
- Sponsor
- AI Labs Group S.L
Severe Nodular Acne
Efficacy and Safety of CIP-Isotretinoin in Patients With Severe Recalcitrant Nodular Acne
The purpose of this study is to compare the efficacy and safety of CIP-Isotretinoin and a marketed (generic) formulation of isotretinoin when both are administered twice daily with meals.
- Trial name
- NCT00975143
- Testing
- CIP-Isotretinoin, Isotretinoin
- Where
- 49 sites in United States, Canada
- Volunteers
- 925 people
- Sponsor
- Cipher Pharmaceuticals Inc.
Acne Vulgaris
A Device Study for the Treatment of Acne
To evaluate the safety and efficacy of the Cutera laser system for the treatment of acne vulgaris.
- Trial name
- NCT04695691
- Testing
- Cutera Laser System
- Where
- 7 sites in United States
- Volunteers
- 104 people
- Sponsor
- Cutera Inc.
Rosacea
A Clinical Trial to Determine the Effects of 40 Mg Doxycycline Versus a Placebo Control for the Treatment of Rosacea
The objective of this study is to evaluate the safety and efficacy of 40 mg doxycycline controlled-release capsules administered once daily for the treatment of rosacea compared with a placebo.
- Trial name
- NCT00126399
- Testing
- doxycycline
- Volunteers
- 528 people
- Sponsor
- CollaGenex Pharmaceuticals
Prosthesis and Bone Infections, Cutibacterium Acnes
Cutibacterium Acnes in Bone and Joint Infections
Prosthetic Joint Infections (PJIs) are increasing with the use of orthopedic devices on an ageing population. Cutibacterium acnes is a commensal organism that plays an important role in the ecosystem healthy human skin, yet this…
- Trial name
- CaBJI (NCT03950063)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- CHU de Reims
Acne Vulgaris
P3 Study in Acne Comparing Once Daily SB204 and Vehicle
This is a 12 week, multi-center, double-blinded, randomized, vehicle-controlled, parallel group, study to be conducted in approximately 1300 subjects with acne vulgaris in the US.
- Trial name
- NCT02672332
- Testing
- SB204 4%, Vehicle Gel
- Where
- 55 sites in United States
- Volunteers
- 1,307 people
- Sponsor
- Novan, Inc.
Acne Vulgaris
Efficacy of Manuka Honey Nano-Formulation in the Treatment of Acne Vulgaris
The present study aims to manufacture manuka honey-loaded nano-formulation using natural materials as a potent tissue-healing remedy and compare it to commercially available antimicrobial therapy in order to reduce the severity…
- Trial name
- NCT06175819
- Testing
- Manuka honey( MgO 850, UMF+20) loaded nano-formulation
- Volunteers
- 102 people
- Sponsor
- Al-Azhar University
Acne Vulgaris
A Study Comparing Two Topicals in the Treatment of Acne Vulgaris
A Randomized, Evaluator-Blinded, Bilateral Comparison Study to Evaluate the Safety and Efficacy of Two Topicals in the Treatment of Subjects With Acne Vulgaris (Study FX2018-23).
- Trial name
- NCT03743038
- Testing
- FMX101 vehicle, Hydro-alcohol solution
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Vyne Therapeutics Inc.
Acne Vulgaris
Vitamin A and Azithromycin for Acne Vulgaris
Patients seen with acne lesions not having responded to existing treatments will be offered a placebo or a topical preparation consisting of Vitamin A USP with or without Azithromycin for a duration of 4-6 months USP for the…
- Trial name
- NCT03090048
- Testing
- Vitamin A, Azithromycin
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Manchanda Medical Clinic
Acne
Effects of Roaccutane on Ca, P, PTH and Vitamin D Metabolites in the Treatment of Sever Acne
serum levels Ca, P, PTH and vitamin D metabolites before and after treatment with isotretinoin for sever acne
- Trial name
- NCT00416585
- Testing
- isotretinoin (Roaccutane)
- Where
- Iran
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences
Acne
A Study to Evaluate the Safety and Efficacy of ASC40 (Denifanstat) Tablets in the Treatment of Patients With Moderate to Severe Acne Vulgaris
This is a multicenter, randomized, double-blind, placebo-controlled Phase III study to evaluate the efficacy and safety of ASC40 (Denifanstat) tablets compared to placebo in the treatment of patients with moderate to severe acne…
- Trial name
- NCT06192264
- Testing
- ASC40
- Where
- 41 sites in China
- Volunteers
- 480 people
- Sponsor
- Ascletis Pharmaceuticals Co., Ltd.
Acne, Demodex Infestation
Demodex Mites in Acne Patients and Herbal Extract Susceptibility
This case-control study aims to detect the presence and density of Demodex mites in patients with acne, identify the species using molecular methods, and evaluate the in vitro survival time of live mites exposed to medicinal…
- Trial name
- NCT07845149
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
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