Clinical trials: acne
Acne Vulgaris
A Safety, Tolerability, Efficacy and Exposure Study of XEN801 Topical Gel
Phase 1/2 study enrolling up to 60 healthy volunteers in Phase 1 followed by approximately 150 subjects with acne vulgaris in Phase 2.
- Trial name
- NCT02656043
- Testing
- XPF-005
- Where
- 20 sites in Canada
- Volunteers
- 213 people, healthy volunteers welcome
- Sponsor
- Xenon Pharmaceuticals Inc.
Acne Vulgaris, Acne
Study of NVN1000 Topical Gel and Topical Gel Vehicle in the Treatment of Moderate to Severe Acne Vulgaris
The primary objective of this study is to compare the tolerability, safety and efficacy of NVN1000 Topical Gel and Topical Gel Vehicle in the treatment of subjects with moderate to severe acne vulgaris.
- Trial name
- NCT01556698
- Testing
- NVN1000, Vehicle
- Where
- Dominican Republic
- Volunteers
- 70 people
- Sponsor
- Novan, Inc.
Acne Vulgaris
A Phase 1 Study Evaluating Safety and Tolerability of NVN1000 Gel
This is a 2 week Phase 1 study of SB204 (NVN1000 Gel) in healthy adult volunteers with elevated Propionibacterium acnes (P. acnes) counts. Subjects will apply NVN1000 4% Gel or Vehicle Gel twice daily to their face.
- Trial name
- NCT01844739
- Testing
- NVN1000 4% Gel, Vehicle Gel
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Novan, Inc.
Acne Vulgaris
A Phase 2, 3 Arm Study of NVN1000 Gel and Vehicle Gel in Subjects With Acne
This is a 12 week clinical trial in subjects with acne vulgaris. Subjects will be randomized to NVN1000 1% Gel, NVN1000 4% Gel or Vehicle Gel twice daily.
- Trial name
- NCT01844752
- Testing
- NVN1000 1% Gel, NVN1000 4% Gel, Vehicle Gel
- Where
- 3 sites in Dominican Republic, Honduras and 1 more
- Volunteers
- 153 people
- Sponsor
- Novan, Inc.
Acne Vulgaris
A Phase 1 Study Assessing Local Cutaneous Effects of SB204
In this study, color (erythema) and pH will be measured on 3 consecutive days after application of 2 doses of SB204 to the cheeks of healthy volunteers.
- Trial name
- NCT02250430
- Testing
- SB204
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Novan, Inc.
Acne Vulgaris
A Thorough ECG Study in Subjects With Acne Vulgaris Treated With SB204
A Double-Blind, Double-Dummy, Randomized, 4-Period Crossover Study to Define the ECG Effects of SB204 Using a Clinical and Supratherapeutic Dose Compared with Placebo and Moxifloxacin (a Positive Control) in Subjects with Acne…
- Trial name
- NCT02581072
- Testing
- SB204 4%, SB204 8% or 12%, Vehicle
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Novan, Inc.
Acne Vulgaris
Pilot Study of Tolerability and Effectivity of Two Combination Topical Acne Products
Study to compare two gels that are used to treat acne vulgaris. It will be compared the tolerability and effectivity following application of two combination topical acne products clindamycin 1% and 0.025% tretinoin gel (Acnatac®…
- Trial name
- PREFECT (NCT02731105)
- Testing
- Acnatac® Gel left face, Epiduo® Gel right face, Acnatac® Gel right face
- Where
- Germany
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- GWT-TUD GmbH
Acne Vulgaris
Efficacy Study in Patients With Acne Vulgaris.
Safety and efficacy study in patients with acne vulgaris
- Trial name
- NCT02935036
- Testing
- ADPS topical product
- Volunteers
- 294 people, healthy volunteers welcome
- Sponsor
- Sun Pharmaceutical Industries, Inc.
Acne Vulgaris
Pharmacokinetics of Topical SB204 in Adolescents With Acne Vulgaris
A Phase 1, Single-center, Open-label, Pharmacokinetic, Safety and Tolerability Study of SB204 in Adolescents with Moderate to Severe Acne Vulgaris
- Trial name
- NCT02801903
- Testing
- SB204 4%
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Novan, Inc.
Acne Vulgaris
A Safety and Efficacy Study of Dapsone Gel in Patients With Acne Vulgaris
This study will assess the safety and efficacy of dapsone gel versus vehicle control in patients with acne vulgaris.
- Trial name
- NCT01974141
- Testing
- Dapsone Gel, Dapsone Gel Vehicle
- Where
- 2 sites in United States, Canada
- Volunteers
- 2,102 people
- Sponsor
- Almirall, S.A.
Acne Vulgaris
Safety and Efficacy Study of Dapsone Gel in Patients With Acne Vulgaris
This study will assess the safety and efficacy of dapsone gel versus vehicle control in patients with acne vulgaris.
- Trial name
- NCT01974323
- Testing
- Dapsone Gel, Dapsone Gel Vehicle
- Where
- 3 sites in United States, Canada
- Volunteers
- 2,238 people
- Sponsor
- Almirall, S.A.
Atrophic Acne Scar
A Study to Evaluate the Efficacy of ELAPR002f in Females and Males With Atrophic Acne Scars
The study is designed to evaluate the efficacy of two formulations of a cross-linked tropoelastin matrix given the product codes ELAPR002f (collectively referred to as ELAPR or ELAPR002) for the treatment of rolling atrophic acne…
- Trial name
- NCT03056235
- Testing
- ELAPR002f, Saline
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Elastagen Pty Ltd
Acne Vulgaris
Effect of Samples on Acne Treatment With Epiduo® Gel
The purpose of this study is to compare adherence to treatment and efficacy with Epiduo® Gel in patients with mild to moderate acne who receive a medication sample and instructions on proper application with their stock size…
- Trial name
- NCT01504204
- Testing
- Adapalene + benzoyl peroxide samples, Adapalene + benzoyl peroxide from standard tube
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Wake Forest University
Acne Vulgaris
Efficacy of Silk - Like Bedding Fabric Pillow Case in the Treatment of Acne Vulgaris
The purpose of this research study is to better understand how this study pillowcase works when people use it to treat acne. Most people, including people with acne, sleep six to eight hours each night in direct contact with…
- Trial name
- NCT00767104
- Testing
- Silk like Pillowcase, Cotton Pillowcase
- Volunteers
- 40 people
- Sponsor
- Wake Forest University
Acne Vulgaris
Analysis of Adherence in Subjects Undergoing Differin Gel, 0.1% Treatment of Moderate to Severe Acne Vulgaris
The primary objective of this study is to investigate potential differences between four treatment intervention groups in the adherence to treatment with Differin® Gel, 0.1%.
- Trial name
- NCT00696449
- Testing
- Adapalene, frequent visits, electronic reminder
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Wake Forest University
Acne Vulgaris
Adherence to Study Medication Compared to Generic Topical Clindamycin Plus Generic Topical Tretinoin in Subjects With Mild to Moderate Acne Vulgaris
The purpose of this research study is to evaluate the effectiveness of two different types of topical acne medication. This study will help to determine if one combined medication results in better acne improvement than two…
- Trial name
- NCT01047189
- Testing
- clindamycin phosphate 1.2% and tretinoin 0.025%, clindamycin 1% gel, tretinoin 0.025% cream
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Wake Forest University
Acne Vulgaris
A Study to Evaluate the Tolerance of an Acne Treatment in Sensitive Skin Subjects With Mild to Moderate Acne Vulgaris
The study will look to evaluate the tolerance of a light therapy-based acne mask device in participants who report having sensitive skin.
- Trial name
- NCT03128723
- Testing
- Acne Mask
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Johnson & Johnson Consumer Inc. (J&JCI)
Acne Vulgaris
Measuring Adherence in Subjects With Acne Vulgaris in a Clinic Population Subtitle: Topical Benzoyl Peroxide for Acne
The purpose of this research study is to see how often benzoyl peroxide is applied for acne. Use of medication was monitored electronically.
- Trial name
- NCT00658112
- Testing
- Benzoyl Peroxide
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Wake Forest University
Acne Vulgaris
DUAC® Early Onset Efficacy Study in Japanese Subjects
This is a multicentre, randomized, single-blind (investigator is blinded), active (the combination therapy of adapalene [ADA] and clindamycin [CLDM])-controlled and parallel-group study in Japanese subjects with facial acne…
- Trial name
- NCT02557399
- Testing
- Duac® fixed dose combination gel, ADA 0.1% gel, CLDM 1% gel
- Where
- 15 sites in Japan
- Volunteers
- 350 people
- Sponsor
- GlaxoSmithKline
Acne Vulgaris
A Study Comparing Tazarotene Cream 0.1% to TAZORAC® (Tazarotene) Cream 0.1% and Both to a Placebo Control in the Treatment of Acne Vulgaris
A Multi-Center, Double-Blind, Randomized, Vehicle-Controlled, Parallel-Group Study Comparing Tazarotene Cream 0.1% to TAZORAC® (Tazarotene) Cream 0.1% and Both Active Treatments to a Vehicle Control in the Treatment of Acne…
- Trial name
- NCT02886715
- Testing
- Tazarotene Cream 0.1%, Tazorac®
- Where
- 25 sites in United States
- Volunteers
- 1,110 people
- Sponsor
- Fougera Pharmaceuticals Inc.