Clinical trials: acne
Hidradenitis Suppurativa (HS), Hidradenitis Suppurativa (Acne Inversa)
Comparison of the Clinical Efficacy and Safety of Topical and Subcutaneous Injection of Secukinumab in HS
Secukinumab is currently approved in Europe, US and China for the treatment of moderate to severe HS as a biologic agent targeting IL-17A.Two phase III clinical trials (SUNSHINE and SUNRISE) showed that 300 mg s.c.
- Conditions
- Hidradenitis Suppurativa (HS), Hidradenitis Suppurativa (Acne Inversa), Secukinumab
- Trial name
- NCT07261072
- Testing
- Topical injection of Secukinmab, Subcutaneous injection of Secukinumab
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Peking Union Medical College
Acne Vulgaris
Topical 5% Spironolactone Gel Versus 0.1% Adapalene Gel for Acne Vulgaris: A Randomized Split-Face Study
Acne vulgaris is one of the most common dermatological conditions affecting adolescents and young adults. It results from multiple pathogenic factors, including increased sebum production, follicular hyperkeratinization…
- Trial name
- NCT07473895
- Testing
- Spironolactone 5% Topical Gel, Adapalene 0.1% Topical Gel
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Assiut University
Acne Vulgaris
A Study to Evaluate the Effectiveness and Tolerance of Two Acne Treatments on Subjects With Mild to Moderate Acne.
This study will compare two different acne treatments for the treatment of acne. Half of the participants will receive two marketed acne products (cleanser and leave-on topical treatment), while the other half of the participants…
- Trial name
- TIGER (NCT02698436)
- Testing
- Acne Mask, 2.5% Benzoyl Peroxide Treatment
- Where
- 2 sites in United States
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer and Personal Products Worldwide
Acne Vulgaris
Study Comparing Test to Aczone 7.5% and Both to a Placebo Control in the Treatment of Acne Vulgaris
To evaluate the therapeutic effect of Dapsone and Placebo gel in the treatment of acne vulgaris.
- Trial name
- NCT04015375
- Testing
- Dapsone gel 7.5% (Torrent Pharmaceuticals Ltd), ACZONE® (dapsone) gel, 7.5% (Allergan, INC.)
- Where
- 13 sites in United States, Belize
- Volunteers
- 1,150 people, healthy volunteers welcome
- Sponsor
- Torrent Pharmaceuticals Limited
Cornea
Comparison of Oral Isotretinoin vs Ancomparison of Oral Isotretinoin vs Antibiotics on Corneal Thickness With AV
Comparison of Oral Isotretinoin versus comparison of Oral Isotretinoin versus Antibiotics on Corneal Thickness in Patients with Acne Vulgaris
- Trial name
- NCT06483971
- Testing
- Oral Isotretinoin, Antibiotics
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Superior University
Acne Vulgaris, Allergic Rhinitis
MedlinePlus Health Prescriptions: Developing a Pragmatic Approach for Clinic Use
The specific aim of this proposed pilot study is to compare two standardized processes (paper and electronic) to deliver a customized MedlinePlus health information prescription.
- Conditions
- Acne Vulgaris, Allergic Rhinitis, Anxiety, Asthma
- Trial name
- NCT01050465
- Testing
- health information prescription
- Volunteers
- 907 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Acne
Clinical Study for Topical Lupeol in Acne
Double-blind, randomized,4-week small-scale clinical trial for lupeol in the treatment of inflammatory and non-inflammatory acne lesions in split face fashion
- Trial name
- NCT02205892
- Testing
- Lupeol
- Where
- South Korea
- Volunteers
- 16 people
- Sponsor
- Seoul National University Hospital
Keloid, Scleroderma, Localized
Ultraviolet B (UVB) Light Therapy in the Treatment of Skin Conditions With Altered Dermal Matrix
This research study will evaluate the effectiveness of high dose UVB light therapy in the treatment of keloid (or hypertrophic scar), scleroderma, acne keloidalis nuchae, old burn scars, granuloma annulare or related conditions.
- Conditions
- Keloid, Scleroderma, Localized, Acne Keloidalis, Scars
- Trial name
- NCT00129428
- Testing
- UVB Irradiation
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Michigan
Acne Vulgaris
Two-week Study to Compare the Tolerance and Irritation Potential of Two Combination Topical Gel Acne Medications
This is a single-blind (blinded expert grader), randomized, half-face study being conducted at one clinical site. On 1 side of the face, the subject will apply 1 of the 2 test products, antibiotic and benzoyl peroxide or benzoyl…
- Trial name
- NCT00926367
- Testing
- Clindamycin and benzoyl peroxide, benzoyl peroxide 2.5% and adapalene 0.1% gel
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Stiefel, a GSK Company
Acne Vulgaris
A Study to Evaluate the Irritation Potential of Tazarotene Foam on Skin in Healthy Volunteers
The purpose of this study is to evaluate the irritation level of tazarotene foam after 21 days of exposure on the skin of healthy volunteers.
- Trial name
- NCT01112787
- Testing
- Tazarotene Foam, Vehicle Foam, Sodium Laural Sulfate
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Stiefel, a GSK Company
Hidradenitis Suppurativa (HS)
A Study Evaluating BFB759 in Moderate to Severe Hidradenitis Suppurativa
This is a double-blind, placebo-controlled study where subjects are participating for approximately 36 to 40 weeks. The study compares how well BFB759 works and how safe it is compared with a placebo.
- Trial name
- COMPASS 2-HS (NCT07287644)
- Testing
- BFB759
- Where
- 64 sites in United States, Bulgaria and 5 more
- Volunteers
- 210 people
- Sponsor
- Bluefin Biomedicine, Inc.
Acne Scars - Atrophic
Nano Fat Injection With or Without Fractional Carbon Dioxide Laser in Acne Scars
Assessment of nano fat grafting combined with carbon dioxide laser resurfacing versus nano fat grafting alone in treating facial atrophic acne scars
- Trial name
- NCT05985265
- Testing
- Fat grafting
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Acne Vulgaris on the Face
Safety and Efficacy of Topical AT-004 1% in Participants With Acne Vulgaris (AV)
Double blinded, randomized, placebo-controlled trial to determine the safety and efficacy of topical AT-004 therapy in participants with acne vulgaris, including assessment of reduction in the number of acne lesions and IGA.
- Trial name
- NCT07774364
- Testing
- AT-004
- Where
- 3 sites in Denmark
- Volunteers
- 63 people
- Sponsor
- Arctic Therapeutics
Acne Vulgaris
BLI1100-202: BLI1100 for the Treatment of Moderate to Severe Acne Vulgaris
The purpose of this study is to compare the safety and efficacy of BLI1100 formulations to placebo for the treatment of moderate to severe acne vulgaris.
- Trial name
- NCT01815450
- Testing
- BLI1100, BLI1100 - modified formulation
- Where
- 15 sites in United States
- Volunteers
- 369 people
- Sponsor
- Braintree Laboratories
Acne Vulgaris
Clinical Study to Evaluate Tolerability and Safety of FXFM244 and to Monitor Clinical Effect in Acne Vulgaris Patients
The purpose of this study is to evaluate the tolerability and safety and to determine whether FXFM244 Antibiotic Foam is effective in the treatment of Acne Vulgaris.
- Trial name
- NCT01362010
- Testing
- Topical Minocycline Foam FXFM244
- Where
- 3 sites in Israel
- Volunteers
- 150 people
- Sponsor
- Vyne Therapeutics Inc.
Acne
A Pharmacokinetic Study of Minocycline in Male and Female Volunteers
The purpose of this study is to assess the pharmakokinetic profile of Minocycline in FMX-101 4% foam product in male and female some of which are with acne
- Trial name
- NCT02250859
- Testing
- FMX101, Minocycline 4% foam
- Where
- Israel
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Vyne Therapeutics Inc.
Acne Vulgaris
MUSE Study to Evaluate the Pharmacokinetics, Safety and Tolerability of S6G5T-3
To assess the degree of systemic exposure of S6G5T-3 compared to the Reference Listed Drug (RLD) Retin-A® 0.1% Cream when applied topically once daily for 14 days, under maximal use conditions in adolescents ≥12 years of age and…
- Trial name
- NCT04059523
- Testing
- S6G5T-3, Retin-A® 0.1% Cream
- Where
- 2 sites in United States
- Volunteers
- 62 people
- Sponsor
- Sol-Gel Technologies, Ltd.
Acne Vulgaris
A Study Assessing the Efficacy of Combined Use of Clascoterone 1% Cream and Adapalene 0.3% for the Treatment of Acne
Winlevi is the first topical anti androgen and sebum inhibitor approved for acne vulgaris. There is no study assessing Winlevi in combination treatment for acne .Therefore this study assesses Winlevi with Adapalene 0.3% gel in…
- Trial name
- NCT06336603
- Testing
- Winlevi (clascoterone) 1% & Adapalene 0.3% gel
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Sun Pharmaceutical Industries Limited
Acne, Scar
Fractional Resurfacing Device for Treatment of Acne Scarring
The purpose of this research study is to evaluate the safety and effectiveness of a new investigational laser device for treatment of acne scarring, for improvement in the appearance of surface texture and topography (recessed or…
- Trial name
- NCT00585286
- Testing
- 10,600 nm fractional carbon dioxide laser system
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of California, Irvine
Shoulder Infection
Skin Prep to Reduce Postoperative Shoulder Infection
Propionibacterium acnes is the most common pathogen identified from a surgical site infection in the shoulder. Standard skin preps do not prevent this type of infection.
- Trial name
- NCT02510144
- Testing
- Skin Prep Chlorhexidine, Skin Prep Benzoyl Peroxide
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Maryland, Baltimore
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