Clinical trials: acne
Acne Vulgaris
Comparison of Malassezia Spp Proportions in Inflammatory and Non Inflammatory Facial Acne Vulgaris Lesions
Acne vulgaris (AV) is a common inflammatory condition involving pilosebaceous unit. The pathogenesis of acne is multifactorial and skin microbiome is considered to be one of the key factors that aggravate inflammation.
- Trial name
- NCT04367584
- Testing
- Clinical and laboratory examination
- Where
- Indonesia
- Volunteers
- 120 people
- Sponsor
- Universitas Indonesia
Acne Vulgaris
Analysis of Adherence in Subjects Undergoing Differin Gel, 0.1% Treatment of Moderate to Severe Acne Vulgaris
The primary objective of this study is to investigate potential differences between four treatment intervention groups in the adherence to treatment with Differin® Gel, 0.1%.
- Trial name
- NCT00696449
- Testing
- Adapalene, frequent visits, electronic reminder
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Wake Forest University
Acne Vulgaris
Study to Determine and Compare the Tolerance and Irritation Potential of Topical Acne Medications
This is a randomized, half-face study. On 1 side of the face, the subject will apply 1 of the 2 test products, clindamycin and benzoyl peroxide or dapsone gel and the contra lateral side of the face will remain non-treated to…
- Trial name
- NCT00964366
- Testing
- clindamycin and benzoyl peroxide, Dapsone gel
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Stiefel, a GSK Company
Acne, Photodynamic Therapy
Topical PDT Cream Without Irradiation Source in the Acne Treatment
In this study, the investigators are going to compare the clinical effect and safety of topical application of 1.5% Butenyl ALA cream formula without light source irradiation in the treatment of acne.
- Trial name
- NCT02313467
- Testing
- Topical application of 1.5% Butenyl ALA
- Where
- South Korea
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Acne Vulgaris
Clinical Study to Test the Efficacy and Safety of Adapalene, 0.1%
The purpose of this study is to determine whether Adapalene, 0.1% is safe and effective in the treatment of Acne Vulgaris.
- Trial name
- NCT00598832
- Testing
- Adapalene lotion 0.1%, Adapalene Lotion Vehicle
- Where
- 34 sites in United States, Canada
- Volunteers
- 1,075 people
- Sponsor
- Galderma R&D
Acne Vulgaris
U0289-402: An Open Label, 8 Week Study to Evaluate the Efficacy and Tolerability of MAXCLARITY II in Subjects With Acne
One of the main success factors in acne therapy is user compliance with treatment, product cost, availability and ease of use. Poor compliance may translate into decreased efficacy (either not improving symptoms well enough or…
- Trial name
- NCT01706263
- Testing
- MAXCLARITY II (2.5% BPO) Foam Cleanser, MAXCLARITY II (2.5% BPO) Foam Treatment, MAXCLARITY II (0.5% Salicylic Acid) Toner Foam
- Volunteers
- 28 people
- Sponsor
- Stiefel, a GSK Company
Hidradenitis Suppurativa
Efficacy and Safety of Olatorepatide Versus Placebo in Adults With Moderate to Severe Hidradenitis Suppurativa Living With Overweight or Obesity
This study will test an experimental Regeneron drug called olatorepatide ("study drug") to see if it can help treat Hidradenitis Suppurativa (HS).
- Trial name
- NCT07830329
- Testing
- Olatorepatide
- Volunteers
- 300 people
- Sponsor
- Regeneron Pharmaceuticals
Acne
Efficacy of Epiduo and Treatment Adherence of Adolescent Patients With Inflammatory Acne
The purpose of this observational study is to assess the efficacy of Epiduo and patient adherence under daily clinical practice conditions in adults and adolescents (12 to 20 years) with moderate inflammatory acne using this drug…
- Trial name
- TEENA (NCT01220102)
- Testing
- 0.1% adapalene/ 2.5% benzoyl peroxide
- Volunteers
- 3,113 people
- Sponsor
- Galderma Laboratorium GmbH
Acne Vulgaris
Effectiveness and Safety of Zingiber Officinale Transdermal Patch for Acne Vulgaris; Study of Interleukin 1 and Skin Microbiome
The goal of this clinical trial is to investigate the effectivity and safety of mild to moderate acne vulgaris therapy using Zingiber officinale 5 % transdermal patch.
- Trial name
- NCT06787222
- Testing
- tretinoin 0.025% + Z. officinale patch, tretinoin 0.025% cream
- Where
- Indonesia
- Volunteers
- 26 people
- Sponsor
- Hasanuddin University
Acne Vulgaris
2940nm Er:YAG Laser Versus Benzoyl Peroxide Gel for the Treatment of Inflammatory Acne
Acne is one of the most common conditions that patients seek for help in dermatological clinic. Nowadays, conventional treatment including topical agents(retinoids, antibiotics ,antiseptics and keratolytic agents) and systemic…
- Trial name
- NCT01472900
- Testing
- 2940 nm Er:YAG laser (DualisXS M002-2A, Fotona®, Fotona d.d, Ljubljana, Slovenia), Benzoyl Peroxide gel
- Where
- Thailand
- Volunteers
- 25 people
- Sponsor
- Chulalongkorn University
Facial Acne Vulgaris
A Study to Evaluate Sebacia Microparticles in Patients With Inflammatory Acne Vulgaris
This study is proposed to evaluate Sebacia Microparticle treatment in patients with facial inflammatory acne vulgaris.
- Trial name
- NCT02758041
- Testing
- Sebacia Microparticles
- Where
- 3 sites in Denmark, Switzerland
- Volunteers
- 85 people
- Sponsor
- Sebacia, Inc.
Carcinoma, Non-Small-Cell Lung, Colorectal Neoplasms
Evaluation of a Cosmetic Product to Preserve Skin Conditions When Using Anti-EGFR Cancer Therapies
It is important for patients treated with anti-EGFR therapies to get access to cosmetic options to preserve their skin condition during treatment.
- Conditions
- Carcinoma, Non-Small-Cell Lung, Colorectal Neoplasms, Head and Neck Neoplasms
- Trial name
- OPERA (NCT04878692)
- Testing
- Application of Onco-Rash cream, Application of Onco-Neutre cream
- Where
- France
- Volunteers
- 96 people
- Sponsor
- Hospices Civils de Lyon
Acne Vulgaris, Acne Scars
Efficacy of Microneedling With Topical Vitamin C in Treatment of Acne Scarring
This study aimed to evaluate the efficacy of dermaroller and topical vitamin C- either separate or combined- in treatment of post acne scars.
- Trial name
- NCT03522922
- Testing
- Dermaroller, Topical Vitamin C
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Sohag University
Acne Vulgaris
A Study to Evaluate the Potential of Tazarotene Foam to Cause an Allergic Reaction When Applied to the Skin and Exposed to Light on Healthy Volunteers.
The purpose of this study is to evaluate the potential of Tazarotene Foam to induce a photoallergic reaction when exposed to UV and VIS light on skin of healthy volunteers.
- Trial name
- NCT01119651
- Testing
- Tazarotene (Patch application in Challenge Phase)
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Stiefel, a GSK Company
Acne
Administration of Oral Extended Release Minocycline for Assessment of Skin and Plasma Concentrations of Minocycline
The primary objective of this study is to evaluate the skin and plasma concentrations of minocycline in subjects undergoing treatment of acne vulgaris with oral extended release minocycline.
- Trial name
- NCT02695446
- Testing
- Minocycline
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- BioPharmX, Inc.
Acne Vulgaris
A Study of Olumacostat Glasaretil Gel in Subjects With Acne Vulgaris
The objectives of this study are to assess the safety and efficacy of Olumacostat Glasaretil Gel compared to vehicle in patients with acne vulgaris
- Trial name
- NCT03073486
- Testing
- Olumacostat Glasaretil Gel, 5.0%, Olumacostat Glasaretil Gel, Vehicle
- Where
- 46 sites in United States, Australia and 1 more
- Volunteers
- 744 people
- Sponsor
- Dermira, Inc.
Acne Vulgaris
The Relationship Between Microbioma Balance and Acne Vulgaris as a New Acne Treatment
Background: Acne vulgaris is a chronic inflammatory condition primarily caused by Cutibacterium acnes, which disrupts skin homeostasis, thereby triggering immune responses and sebum metabolism.
- Trial name
- NCT06925386
- Testing
- Standard therapy, HEXBIO, Secretome
- Where
- Indonesia
- Volunteers
- 64 people
- Sponsor
- Universitas Padjadjaran
Moderate to Severe Acne Vulgaris
Clinical Trial of Microneedle Radiofrequency Combined With Oral Isotretinoin in Moderate to Severe Acne
This study plans to select 100 AV patients and randomly divide them into two groups in a 1:1 ratio: the experimental group will be treated with MRF combined with oral isotretinoic acid for 8 consecutive weeks, with a total of 3…
- Trial name
- NCT06378983
- Testing
- Oral isotretinoin, Oral isotretinoin combined with microneedle radiofrequency therapy
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Acne Vulgaris
Comparison of Topical Clascoterone and Adapalene for Mild Acne Vulgaris
There is no local data available regarding the comparative efficacy of topical clascoterone and topical adapalene, particularly in patients with mild acne vulgaris.
- Trial name
- NCT07673094
- Testing
- Clascoterone Cream 1%, Adapalene 0,1% cgel
- Volunteers
- 60 people
- Sponsor
- Khyber Teaching Hospital
Acne Vulgaris
Long-term Study of Epiduo in Patients With Moderate to Severe Acne
This observational study is designed to assess the long-term efficacy and safety of Epiduo (alone or in combination with other drugs) under daily clinical practice conditions in patients with moderate to severe inflammatory acne.
- Trial name
- ELANG (NCT01618773)
- Testing
- 0.1% adapalene / 2.5% benzoyl peroxide
- Volunteers
- 6,036 people
- Sponsor
- Galderma Laboratorium GmbH
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