Clinical trials: acne
Acne Vulgaris
Combination Therapy With Differin® Gel 0.3% and Duac® (Clindamycin/Benzoyl Peroxide Gel) in Subjects With Acne Vulgaris
This study is to determine the efficacy and safety of 12 week treatment with Differin® Gel 0.3% applied in the evening, in combination with Duac® (Clindamycin/Benzoyl Peroxide Gel) applied in the morning, in Subjects with Acne…
- Trial name
- NCT00671749
- Testing
- adapalene gel, 0.3%, clindamycin/benzoyl peroxide gel
- Where
- 4 sites in United States
- Volunteers
- 100 people
- Sponsor
- Galderma R&D
Acne Vulgaris
Safety and Efficacy Study of Clindamycin/Benzoyl Peroxide/Tazarotene Cream in Subjects With Acne
Benzoyl peroxide, clindamycin and tazarotene are known to be effective treatment alternative for acne vulgaris. The purpose of this study is to assess the safety and efficacy of a combination product including these actives for…
- Trial name
- NCT00713609
- Testing
- Benzoyl peroxide gel, Clindamycin gel, Tazarotene cream
- Where
- 16 sites in United States
- Volunteers
- 591 people
- Sponsor
- Stiefel, a GSK Company
Acne Vulgaris, Acne
Safety and Preliminary Efficacy of Combination Therapy for the Treatment of Acne Vulgaris
Acne vulgaris is a multifactorial, highly prevalent dermatologic condition that results in visible lesions that can be quite disfiguring.
- Trial name
- NCT02431494
- Testing
- Blue light phototherapy, Microcurrent therapy, Combination of BLP and Microcurrent
- Where
- 2 sites in United States
- Volunteers
- 4 people
- Sponsor
- Nova Southeastern University
Acne Scars - Mixed Atrophic and Hypertrophic, Acne
Pilot Study Investigating the Efficacy of Fat Grafting as a Treatment for Male and Female Facial Acne Scarring
This single-center, clinical trial consists of a one autologous fat grafting treatment followed by 3-month and 6-month post-treatment visits in order to assess the efficacy of fat grafting when used by men and women with facial…
- Trial name
- NCT04559022
- Testing
- Fat Grafting
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Acne Vulgaris
GA YAZ ACNE in China Phase III
The purpose of this study is to evaluate the efficacy and safety of YAZ (drospirenone 3 mg / ethinylestradiol 20 µg) in comparison with placebo in female patients with moderate acne vulgaris over 6 treatment cycles.
- Trial name
- NCT00818519
- Testing
- EE20/Drospirenone (YAZ, BAY86-5300)
- Where
- 7 sites in China
- Volunteers
- 179 people
- Sponsor
- Bayer
Hidradenitis Suppurativa
This Was a Study of Efficacy and Safety of Two Secukinumab Dose Regimens in Subjects With Moderate to Severe Hidradenitis Suppurativa (HS).
The purpose of this study was to demonstrate superiority of secukinumab at Week 16, based on Hidradenitis Suppurativa Clinical Response (HiSCR) rates versus placebo, along with the maintenance of efficacy of secukinumab at Week…
- Trial name
- SUNSHINE (NCT03713619)
- Testing
- secukinumab
- Where
- 111 sites in United States, Argentina and 27 more
- Volunteers
- 544 people
- Sponsor
- Novartis Pharmaceuticals
Acne Vulgaris
Treatment of Acne Vulgaris With Doryx Tablets Compared to Doxycyline Hyclate
Randomized, multi-center, open label, active-comparator study to compare the efficacy and tolerability of Doryx Delayed Release Tablets to doxycycline hyclate in patients with moderate to severe acne vulgaris.
- Trial name
- NCT00635609
- Testing
- Doxycycline hyclate (Doryx), Doxycycline hyclate
- Where
- 4 sites in United States
- Volunteers
- 93 people
- Sponsor
- Warner Chilcott
Acne Vulgaris
A Study of Olumacostat Glasaretil Gel in Subjects With Acne Vulgaris
The objectives of this study are to assess the safety and efficacy of Olumacostat Glasaretil Gel compared to vehicle in patients with acne vulgaris
- Trial name
- NCT03028363
- Testing
- Olumacostat Glasaretil Gel, 5.0%, Olumacostat Glasaretil Gel, Vehicle
- Where
- 49 sites in United States, Australia and 1 more
- Volunteers
- 759 people
- Sponsor
- Dermira, Inc.
Acne Vulgaris
Randomized, Double-blind, Placebo-controlled Study to Evaluate Safety & Efficacy of Sarecycline in Treatment of Acne
To evaluate the efficacy and safety of an approximate 1.5 mg/kg/day dose of oral sarecycline compared to placebo in the treatment of moderate to severe facial acne vulgaris
- Trial name
- NCT02322866
- Testing
- Sarecycline
- Where
- 57 sites in United States
- Volunteers
- 1,034 people
- Sponsor
- Almirall, S.A.
Acne Vulgaris
A Study of the Safety and Efficacy of DFD-03 Lotion in the Treatment of Acne Vulgaris for 12 Weeks
Enrollment of subjects with mild to moderate facial acne vulgaris. Co-Primary efficacy endpoints included: Absolute change from Baseline to Week 12 in the inflammatory lesion counts on the face Absolute change from Baseline to…
- Trial name
- NCT03292640
- Testing
- DFD-03 (0.1% tazarotene) Lotion
- Where
- United States
- Volunteers
- 547 people
- Sponsor
- Dr. Reddy's Laboratories Limited
Acne Scars - Mixed Atrophic and Hypertrophic
Comparison of 1,550 and 755 Laser in a Split-face Trial
Clinical Trial comparing the 1,550-nanometer fractionated photothermolysis system laser to the 755 nanometer picosecond laser using a split-face (Right-Left) comparison.
- Trial name
- NCT03988049
- Testing
- 1,550 fracionated photothermolysis laser, 755 picosecond laser
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- David Smart
Acne Vulgaris
Clinical Study to Test the Efficacy and Safety of Adapalene, 0.1%
The purpose of this study is to determine whether Adapalene, 0.1% is safe and effective in the treatment of Acne Vulgaris.
- Trial name
- NCT00599521
- Testing
- Adapalene lotion 0.1%, Adapalene Lotion Vehicle
- Where
- 34 sites in United States, Canada
- Volunteers
- 1,067 people
- Sponsor
- Galderma R&D
Acne Vulgaris
Study to Evaluate Safety & Efficacy of Sarecycline in Treatment of Acne
To evaluate the efficacy and safety of an approximate 1.5mg/kg/day dose of oral sarecycline compared to placebo in the treatment of moderate to severe facial acne vulgaris
- Trial name
- NCT02320149
- Testing
- Sarecycline
- Where
- 57 sites in United States
- Volunteers
- 968 people
- Sponsor
- Almirall, S.A.
Hidradenitis Suppurativa
Evaluation of Sonelokimab for the Treatment of Patients With Active Moderate to Severe Hidradenitis Suppurativa
This is a study to demonstrate the clinical efficacy and safety of the nanobody® sonelokimab administered subcutaneously (sc) compared with placebo in the treatment of adult participants with moderate to severe hidradenitis…
- Trial name
- NCT05322473
- Testing
- Sonelokimab (M1095), Adalimumab
- Where
- 57 sites in United States, Bulgaria and 5 more
- Volunteers
- 234 people
- Sponsor
- MoonLake Immunotherapeutics AG
Acne Vulgaris
Evaluation of Efficacy and Tolerance of Crystal Peel in the Treatment of Adults Presenting Facial Mild Acne
The goal of this interventional, confirmatory and post market study is to evaluate the efficacy and clinical performance of Crystal Peel in adults suffering mild facial acne vulgaris.
- Trial name
- NCT05821296
- Testing
- Crystal Peel
- Where
- Poland
- Volunteers
- 42 people
- Sponsor
- Dermosciences France
Acne Vulgaris
Knowledge Evaluation and Assessment of the Effectiveness of an Education Intervention on Acne
Acne vulgaris is a chronic inflammatory disorder of the skin in the pilosebaceous unit of the hair follicle, associated with oil production.
- Trial name
- NCT01629797
- Testing
- Educational script on Acne
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Northwestern University
Wrinkles, Fine Lines
Feasibility Study To Collect Safety And Preliminary Efficacy Data For A Radiofrequency Microneedling Device
The intended use of the Potenza™ device is to collect clinical data for brow lifting and/or treatment of dermatologic conditions in which electrocoagulation and hemostasis is a viable mechanism for means of improvement.
- Conditions
- Wrinkles, Fine Lines, Crepey Skin, Acne Scars
- Trial name
- NCT05254210
- Testing
- RF Device (Potenza™)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Cynosure, Inc.
Acne Vulgaris
A Phase 4, Single-Blind, Randomized, Study to Compare the Tolerability and Efficacy of 0.1% Tazorac Cream When Used in Combination With Either Duac Gel or Acanya Gel for the Treatment of Facial Acne Vulgaris
A single-blind (investigator-blinded), randomized, parallel group, single center study to evaluate the tolerability and efficacy of combination therapy with Duac Gel / 0.1% Tazorac Cream and Acanya Gel / 0.1% Tazorac Cream for…
- Trial name
- C0000-411 (NCT01016977)
- Testing
- Clindamycin 1%/Benzoyl Peroxide 5% and 0.1% tazarotene, clindamycin phosphate 1.2%/benzoyl peroxide 2.5% and 0.1% tazarotene
- Volunteers
- 40 people
- Sponsor
- Stiefel, a GSK Company
Acne Vulgaris
Assessment of Subjects' Efficacy and Experiences Using Adapalene BPO Gel in the Treatment of Acne Vulgaris
The purpose of this study is to assess subjects' experiences using Adapalene BPO gel to treat mild to moderate acne vulgaris using efficacy measurements, quality of life instruments, and video diaries.
- Trial name
- NCT01209949
- Testing
- Adapalene 0.1% and Benzoyl Peroxide 2.5% gel
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Galderma R&D
Acne Vulgaris, Atrophic Acne Scars
Adapalene 0.3% - Benzoyl Peroxide 2.5% Gel and Risk of Formation of Atrophic Acne Scars
This was a multi-centre, randomized, investigator blinded, vehicle controlled trial using intra-individual comparison (right half-face versus left half-face).
- Trial name
- OSCAR (NCT02735421)
- Testing
- ABPO Forte Gel, Vehicle gel
- Where
- 7 sites in Canada, France
- Volunteers
- 67 people
- Sponsor
- Galderma R&D