Clinical trials: acne, open to volunteers
Acne Scars - Mixed Atrophic and Hypertrophic, Hyperpigmentation
Efficacy and Tolerability of a Hybrid Fractional Laser for the Treatment of Acne Scars in Patients With Skin of Color
The investigators aim to investigate the efficacy and tolerability of a hybrid non-ablative/ablative laser for acne scarring in skin of color.
- Conditions
- Acne Scars - Mixed Atrophic and Hypertrophic, Hyperpigmentation, Laser-Induced Hyperpigmentation
- Trial name
- NCT05362929
- Testing
- Sciton Halo
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Acne Vulgaris
Investigating the Efficacy of Oral Probiotics Versus Placebo in Pakistani Patients With Moderate Acne on Acne Lesion Count and Systemic Inflammation
This randomized controlled trial evaluates the efficacy of oral probiotics compared to placebo in Pakistani patients with moderate Acne Vulgaris.
- Trial name
- Acne vulgaris (NCT07539129)
- Testing
- Probiotics
- Where
- Pakistan
- Volunteers
- 64 people
- Sponsor
- Foundation University Islamabad
Acne
Safety and Efficacy of Skincare Products for Managing Mild to Moderate Acne in Individuals With Sensitive Skin
To investigate the safety and efficacy of a skincare regimen in individuals with mild to moderate acne and sensitive skin. The study duration is 4 weeks and the skin assessment will be carried out at baseline and week 4.
- Trial name
- NCT07749469
- Testing
- Cleanser, Toner, Serum
- Where
- Malaysia
- Volunteers
- 34 people
- Sponsor
- USMARI Research & Innovation Centre
Acne Vulgaris
Comparing Nadifloxacin Plus Tretinoin Versus Clindamycin Plus Tretinoin Creams for Mild-to-Moderate Acne
The purpose of this randomized controlled trial is to compare the effectiveness of two topical combination treatments for mild-to-moderate acne vulgaris: 1% nadifloxacin with 0.025% tretinoin cream versus 1% clindamycin with…
- Trial name
- NCT07915648
- Testing
- nadifloxacin, Tretinoin Cream 0.025%, Clindamycin
- Where
- Pakistan
- Volunteers
- 158 people
- Sponsor
- Nishtar Medical University
Acne
A Split-Face Comparative Study of Mono Threads Versus Combination With Plasma Gel for the Treatment of Post-Acne Scars
This study aims to evaluate and compare the efficacy and safety of mono threads alone versus mono threads combined with plasma gel for the treatment of atrophic post-acne scars.
- Trial name
- NCT07903012
- Testing
- polydioxanone (PDO) mono threads, Mono Threads with Plasma Gel
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Tanta University
Acne Vulgaris
Efficacy of Dihydroartemisinin for Treating Acne Vulgaris
The goal of this clinical trial is to learn if dihydroartemisinin (DHA) works to treat Acne Vulgaris in adults. The main question it aims to answer is: Does DHA improve the acne severity by at least one grade after treatment.
- Trial name
- NCT07007078
- Testing
- dihydroartemisinin
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shanghai Zhongshan Hospital
Acne
A Clinical Trial to Investigate the Efficacy and Safety of GenLabs' Social Renew on Improving Acne Symptoms and Skin Repair Among Healthy Adults
The goal of this interventional clinical trial is to investigate the efficacy and safety of GenLabs' Social Renew on improving acne symptoms and skin repair among healthy adults.
- Trial name
- NCT07127523
- Testing
- Social Renew
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- GenCanna Acquisition Corp
Acne Vulgaris
Excimer Light Versus Blue Light in Acne
The aim is to assess the efficacy and safety of Excimer Light versus blue light in the treatment of inflammatory acne.
- Trial name
- NCT06725303
- Testing
- Excimer
- Volunteers
- 24 people
- Sponsor
- Cairo University
Acne Vulgaris
Clinical Trial to Compare Oral Isotretinoin to Standard of Care in Moderate Acne Skin of Color Patients
In Dermatology, assessment of people of color remains underrepresented in RCTs (<10%) and guidelines. Acne affects around 9% of the population worldwide and negatively affects quality of life and self-esteem with anxiety…
- Trial name
- ETHNIC (NCT06447480)
- Testing
- ISOtretinoin 5 MG, Topical cream
- Where
- 19 sites in France, French Guiana
- Volunteers
- 420 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Acne
Non-interventional Translational Study in Mild, Moderate and Severe Acne Patients
This study aims to uncover the specific immunopathology, microbiome and pathophysiology of acne vulgaris in people living in a tropical climate such as Singapore.
- Trial name
- VBE00011 (NCT07411638)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Skin Centre
Acne Vulgaris on the Face
Efficacy and Tolerability of DispersinB Acne Cleanser in the Treatment of Mild to Moderate Acne Vulgaris
This is a single-center study using intra-individual comparison (right half-face versus left half-face) to evaluate the efficacy and tolerability of DispersinB Acne Cleanser for treatment of acne in adults.
- Trial name
- NCT06729450
- Testing
- DispersinB Acne Cleanser
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Kane Biotech Inc
Acne
Safety of the Acne mRNA Vaccine in Adolescents 12 to 17 Years of Age With Moderate to Severe Acne
The purpose of this study is to assess the safety profile of intramuscular injections of the Acne mRNA vaccine at 3 dose levels compared with placebo in 12 to 17 years old participants with moderate to severe acne.
- Trial name
- NCT07756957
- Testing
- Acne mRNA (messenger ribonucleic acid) vaccine
- Volunteers
- 410 people
- Sponsor
- Sanofi
Acne-prone Skin, Skin Disease
Observational Assessment of Skin Appearance Changes During PRX S Cosmetic Treatment in Participants With Acne-Prone Skin
This pilot cohort study evaluates changes in skin surface appearance in adult participants with acne-prone skin during and following a standardized five-session course of PRX S (WiQo SpA), a topical cosmetic product designed for…
- Trial name
- NCT07866131
- Testing
- PRX S topical cosmetic treatment, WiQo home care regimen (Nourishing Cream; Balancing Cream)
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- WiQo S.p.A.
Atrophic Acne Scar
Phenytoin in Treatment of Atrophic Post Acne Scars.
To evaluate the efficacy and safety of topical phenytoin spanlastics as an adjuvant therapy in treatment of atrophic post acne scars.
- Trial name
- NCT06942468
- Testing
- Topical nano preparation of Phenytoin, Fractional CO2 laser
- Volunteers
- 30 people
- Sponsor
- Assiut University
Acne
Study to Evaluate Safety, Efficacy and Immunogenicity of Acne mRNA Vaccine in Adults With Moderate to Severe Acne
The purpose of the trial is to evaluate the safety, efficacy and immunogenicity of up to 3 intramuscular injections of the Acne mRNA vaccine candidate at up to four dose levels in adult participants aged 18 to 45 years with…
- Trial name
- NCT06316297
- Testing
- Acne mRNA vaccine
- Where
- 94 sites in United States, Australia and 2 more
- Volunteers
- 800 people
- Sponsor
- Sanofi Pasteur, a Sanofi Company
Post-Acne Atrophic Scars, Carbon Dioxide Lasers
PRP Plus Fractional CO₂ Laser for Acne Scars
This randomized controlled trial aims to evaluate whether adding platelet-rich plasma (PRP) to fractional CO₂ laser resurfacing improves the treatment of moderate-to-severe acne scars compared with laser alone.
- Conditions
- Post-Acne Atrophic Scars, Carbon Dioxide Lasers, Platelet-Rich Plasma
- Trial name
- PRPLT (NCT07352215)
- Testing
- Fractional CO₂ Laser + Platelet-Rich Plasma (PRP), Fractional CO₂ Laser Only
- Where
- Pakistan
- Volunteers
- 70 people
- Sponsor
- Gujranwala medical college District Headquarters Hospital, Gujranwala
Polyendocrine Metabolic Ovarian Syndrome, Acne Vulgaris
Prevalence of Polyendocrine Metabolic Ovarian Syndrome in Patients Diagnosed With Acne Vulgaris in Sohag University Hospital
The aim of this study is to determine the prevalence of polyendocrine metabolic ovarian syndrome (PMOS) among female patients diagnosed with acne vulgaris in Sohag university hospital
- Trial name
- NCT07822360
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Sohag University
Acne Vulgaris
The Impact of Baseline Hormonal Profiles (DHEAS, FSH, LH) on Treatment Response to Systemic Isotretinoin in Adult Female Patients With Acne Vulgaris
Acne vulgaris is a common dermatological condition in adult women, often influenced by hormonal factors. Androgens such as dehydroepiandrosterone sulfate (DHEAS) can stimulate sebaceous gland activity, while gonadotropins (FSH…
- Trial name
- NCT07818525
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Biruni University
Acne Scars
Efficacy of Combined Fractional Er:Glass and Thulium Lasers Versus Microneedling for Atrophic Acne Scars
The purpose of this study is to compare two treatments for acne scars on the face. The study will test whether fractional lasers (Erbium:Glass and Thulium) lead to better improvement in acne scars than microneedling.
- Trial name
- NCT07151599
- Testing
- Microneedling, Fractionated Er:Glass Laser combined to Fractionated Thulium Laser
- Where
- Brazil
- Volunteers
- 84 people
- Sponsor
- University of Nove de Julho
Acne
Study to Evaluate Safety, Efficacy and Immunogenicity of Acne mRNA Vaccine in Participants With Mild Acne
The purpose of the VBE00009 study is to evaluate the safety, efficacy and immunogenicity of 2 administrations of the Acne mRNA vaccine candidate at single dose level in participants aged 18 to 45 years with mild acne.
- Trial name
- NCT07013747
- Testing
- Acne mRNA vaccine
- Where
- 4 sites in United States
- Volunteers
- 228 people
- Sponsor
- Sanofi Pasteur, a Sanofi Company