Clinical trials: bipolar, open to volunteers
Depression, Bipolar Affective Disorder
Effectiveness of Digital Cognitive Behavioral Therapy for the Treatment of Depression: a Real-world Study
The project proposes to develop a digital product based on cognitive behavioral therapy for the assisted treatment of depression.
- Conditions
- Depression, Bipolar Affective Disorder, Schizophenia Disorder, Psychiatric &Amp;or Mood Disorder
- Trial name
- NCT06831435
- Testing
- a digital product based on CBT
- Where
- China
- Volunteers
- 325 people
- Sponsor
- Peking University
Diabetes (DM), Diabete Mellitus
Precision Subclassification of Mental Health in Diabetes: Digital Twins for Precision Mental Health to Track Subgroups
Mental conditions and disorders (e.g. distress, depressive, anxiety, and eating disorders) are more prevalent in people with diabetes (PWD) and associated with reduced quality of life and impaired glycaemic outcomes.
- Conditions
- Diabetes (DM), Diabete Mellitus, Diabete Type 1, Diabete Type 2
- Trial name
- TwinPeaks (NCT07212075)
- Where
- 3 sites in Germany
- Volunteers
- 1,809 people
- Sponsor
- Forschungsinstitut der Diabetes Akademie Mergentheim
Bipolar Disorder I
Melatonin and Response to Lithium
Bipolar disorders are mental illnesses characterized by the recurrence of mood-episodes, that can have a severe impact on the life of individuals.
- Trial name
- MeLiR (NCT05878730)
- Testing
- urine collection, Level of Proteins, Level of mRNA and miRNA
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Bipolar Disorder (BD)
A Study of Home-use Brain Stimulation to Treat Bipolar Depression
Bipolar depression is a long-lasting and disabling condition, and many people continue to experience depressive symptoms despite standard treatments.
- Trial name
- BDEP (NCT07556692)
- Testing
- Flow FL-100 tDCS headset
- Where
- United Kingdom
- Volunteers
- 212 people
- Sponsor
- King's College London
Bipolar Disorder (BD), Bipolar 1 Depression
Neuromodulation of Mood Switch Circuitry in Bipolar Disorder
This study is exploring a new approach to treating depression in people with bipolar disorder (BD). Investigators are testing whether a non-invasive form of brain stimulation can help us understand depressed-to-euthymic mood…
- Conditions
- Bipolar Disorder (BD), Bipolar 1 Depression, rTMS, fMRI
- Trial name
- CircuitBD (NCT07680153)
- Testing
- MagVenture MagPro TMS system
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Weill Medical College of Cornell University
Schizophrenia, Bipolar Disorder
App and Body Fat Scale in the Management of Overweight Patients
This study tests whether using a health app (Huawei Health) and a smart body fat scale can help overweight patients with schizophrenia or bipolar disorder lose weight and stay engaged in their health. What We're Testing: 1.
- Conditions
- Schizophrenia, Bipolar Disorder, Metabolic Syndrome, Overweight and Obesity
- Trial name
- NCT05866107
- Testing
- Effectiveness and Feasibility of Self-Monitoring for Weight Management in Individuals with Mental Disorders Using Digital Intervention ("SWIM" trial)
- Where
- China
- Volunteers
- 204 people
- Sponsor
- Capital Medical University
Schizophrenia and Related Disorders, Bipolar Disorder
Exercise Therapy in Mental Disorders-study
The study will compare standard high-intensity training with brief high-intensity training in people with schizophrenia-spectrum or bipolar disorder.
- Trial name
- NCT06313918
- Testing
- High intensity training (HIT)
- Where
- Norway
- Volunteers
- 50 people
- Sponsor
- Haukeland University Hospital
Psychiatric Disorder
Familial and Functional Study of Genetic Variants Identified in People With Schizophrenia, Bipolar Disorder, Autism Spectrum Disorder or Resistant Depression
Genetic analyses conducted on patient with psychiatric disorders assessed at the expert centres resulted in the identific action of genetic variants associated with psychiatric disorders (Courtois, 2020).
- Trial name
- GENI (NCT05480826)
- Testing
- study of the transmission of genetic variants
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Fondation FondaMental
Borderline Personality Disorder (BPD), Treatment-Resistant Major Depressive Disorder
Ketamine With Dialectical Behavioural Therapy (DBT) for Suicidality in Individuals With Treatment-Resistant Depression and Borderline Personality Disorder (KET-DBT)
The goal of this clinical trial is to learn if intravenous (IV) ketamine with Dialectical Behavioural Therapy (DBT) reduces suicidal ideation in individuals with suicidality who have been diagnosed with Borderline Personality…
- Conditions
- Borderline Personality Disorder (BPD), Treatment-Resistant Major Depressive Disorder, Treatment-resistant Bipolar Depression, Major Depressive Disorder (MDD)
- Trial name
- KET-DBT (NCT07569198)
- Testing
- Ketamine Hydrochloride, Midazolam Hydrochloride, Dialectical Behavioral Therapy (DBT)
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- Joshua Rosenblat
Lurasidone Cardiotoxicity, Schizophrenia Patients
Effects of Lurasidone on Left Ventricle Systolic Functions
The goal of our study to learn if lurasidone molecule which is used on patients with schizophrenia or bipolar disorder has any cardiotoxic effect.
- Conditions
- Lurasidone Cardiotoxicity, Schizophrenia Patients, Bipolar Disorders
- Trial name
- Lurasidone (NCT06695676)
- Testing
- Global Longitudinal Strain
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Major Depressive Disorder (MDD), Schizophrenia
Biomarker Research on Ultra-High-Field MRI Combined With Visual Perception Assessment in the Diagnosis and Treatment Outcomes of Severe Mental Disorders
This is an observational study aiming to screen biomarkers associated with the diagnosis and treatment outcomes of severe mental disorders (MDD/major depressive disorder, SZ/schizophrenia, BD/bipolar disorder) through 7T…
- Conditions
- Major Depressive Disorder (MDD), Schizophrenia, Bipolar Disorder, Severe Mental Disorders
- Trial name
- NCT07479758
- Where
- China
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine