Clinical trials: bipolar
Metastatic Castration-Resistant Prostate Adenocarcinoma, Stage IVB Prostate Cancer AJCC v8
Testing the Use of High Dose Testosterone Followed by Darolutamide Compared to the Usual Care for Patients With Metastatic Prostate Cancer
This phase II/II trial compares the effect of high dose testosterone followed by darolutamide with the usual care in treating patients with prostate cancer that has spread from where it first started (primary site) to other…
- Trial name
- NCT07852195
- Testing
- Abiraterone Acetate, Biospecimen Collection, Bone Scan
- Volunteers
- 432 people
- Sponsor
- ECOG-ACRIN Cancer Research Group
Bipolar Disorder
Cost- Effectiveness and Quality of Life Assessment in Bipolar Disorder Depressive Episode
To evaluate the effectiveness of an algorithm for Bipolar Disorder depressive episodes (BDD) using medications available in the Brazilian Public Healthcare System (SUS).
- Trial name
- NCT02918097
- Testing
- Lithium Carbonate, Sertraline, Nortriptyline
- Volunteers
- 78 people
- Sponsor
- Federal University of Rio Grande do Sul
Mental Disorder, Schizophrenia
A Trial to Assess a Wearable Patch's Functioning to Detect Medication Ingestion
The primary purpose of the study is to evaluate the positive detection accuracy (PDA) and detection latency measures of the D-Tect patch.
- Conditions
- Mental Disorder, Schizophrenia, Major Depressive Disorder, Bipolar I Disorder
- Trial name
- NCT06372210
- Testing
- Abilify MyCite®, D-Tect Patch
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Pelvic Organ Prolapse
SORD-BILL Vs Conventional Options During Sacral Colpopexy for POP
This prospective randomized pilot study is aimed to verify if the operative time of a standard laparoscopic sacral colpopexy associated to subtotal hysterectomy for the treatment of POP could be further reduced using PKS BILL…
- Trial name
- NCT02479685
- Testing
- PKS BILL-PKS PlasmaSORD Versus Conventional surgical techniques
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Catholic University of the Sacred Heart
Bipolar Disorder (BD)
Anticipating Depressive and Manic Episodes in Bipolar Disorders Using Vocal Biomarkers
Bipolar disorder (BD) is a chronic, cyclical mental illness affecting over 1% of the global population. It is characterized by alternating episodes of elevated mood and energy (mania or hypomania) and episodes of decreased mood…
- Trial name
- SPEECHBIPO (NCT07298278)
- Testing
- Voice interviews and questionnaires carried out via the CALLYOPE application, Sleep measurements using an under-mattress sensor, Smartwatch for measuring activity, sleep, and skin temperature
- Volunteers
- 170 people
- Sponsor
- Centre Hospitalier St Anne
Bipolar Disorder
Dysbindin-antipsychotics Psychophamarcogenetics: a Mouse-human Translational Study Towards Personalized Healthcare in Bipolar Disorders
We will conduct an observational study involving a preliminary long-term follow-up designed to test how dysbindin-1 gene expression can modulate the efficacy of treatments with antipsychotics on clinical and neuropsychological…
- Trial name
- DYSBIP (NCT06167577)
- Testing
- Psychometric scales (BPRS, MRS, HAM-D, SES, and GAF) monthly
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Bipolar Disorder, Pregnancy
Antimanic Drug Use in Pregnancy
The purpose of this study is to learn about the effects of bipolar disorder or the use of antimanic medications on the mother's health and wellbeing during pregnancy and for the first postpartum year.
- Trial name
- AMUP (NCT00585702)
- Where
- United States
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Bipolar Disorder
Effectiveness of Two Self Assessment Tools: KIOS-Bipolar or eMoods
The goal of this project is to complete the development of a patient-centered software system and mobile app to assist in managing bipolar disorder.
- Trial name
- NCT02418910
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Metacognitive Capacities
Psychological Factors In The Treatment Of Bipolar Mood Disorders
The aim of this study is to trial an intervention targeting potential deficits in an individual's ability to form, and reflect upon, ideas about themselves and others (known as metacognitive capacities), specifically in relation…
- Trial name
- NCT03266679
- Testing
- Metacognitive Reflection and Insight Therapy - Adapted
- Where
- 2 sites in Australia
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Queensland University of Technology
Bipolar Disorder
Study of Licarbazepine in the Treatment of Manic Episodes of Bipolar Disorder
This purpose of this study is to evaluate the safety and efficacy of Licarbazepine for the treatment of manic episodes of bipolar disorder.
- Trial name
- NCT00099229
- Testing
- Licarbazepine
- Where
- 22 sites in United States, France and 1 more
- Volunteers
- 320 people
- Sponsor
- Novartis Pharmaceuticals
Bipolar Disorder
Early Intervention for Youth at High Risk for Bipolar Disorder
Investigators will conduct a confirmatory efficacy trial of Interpersonal and Social Rhythm Therapy (IPSRT) delivered via telehealth for offspring of bipolar parents (OBP; age 12-18, n=120) at elevated risk for BP onset via risk…
- Trial name
- KEY (NCT04815239)
- Testing
- Interpersonal and Social Rhythm Therapy (IPSRT), The Healthy Lifestyle Behavior Intervention (HL)
- Where
- United States
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Bipolar Disorder, ADHD
Spectroscopy in Children and Adolescents With Bipolar Disorder
The primary aim of this study is to use proton magnetic resonance spectroscopy to look at myo-Inositol containing compounds (Ino) and creatine + phosphocreatine (Cr) in the anterior cingulate of 20 children with bipolar disorder…
- Trial name
- NCT00181831
- Testing
- Proton Magnetic Resonance Spectroscopy
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Bipolar Disorder
Taurine in Adolescents With Bipolar Disorder
Recently, McLean hospital conducted a 4 month taurine study which showed a reduction in mania ratings. As a follow-up to the preliminary taurine study, and complementary to the currently ongoing double-blind, placebo-controlled…
- Trial name
- NCT00391001
- Testing
- Taurine
- Where
- 2 sites in United States
- Volunteers
- 4 people
- Sponsor
- Cambridge Health Alliance
Axilla Node Dissection
Axillary Lymphadenectomy. A Randomized Trial Comparing Bipolar Vessel Sealing To Conventional Technique
lymphorrehea remains the most frequent complication after axillary lymphadenectomy. we hyphothesize that the use of a bipolar vessel sealing may reduce the rate of lymph collection compared to the traditional surgical technique
- Trial name
- NCT01286337
- Testing
- bipolar vessel sealing, control
- Where
- Italy
- Volunteers
- 116 people
- Sponsor
- University of Milano Bicocca
Bipolar Disorder
A Study to Evaluate the Efficacy of FK949E in Bipolar Disorder Patients With Major Depressive Episodes
In period I, the treatment effect of FK949E was compared with that of placebo in a blind manner in bipolar disorder patients with major depressive episodes. In period II, the long-term safety and efficacy of FK949E was evaluated.
- Trial name
- NCT01725308
- Testing
- FK949E
- Where
- 98 sites in Japan
- Volunteers
- 431 people
- Sponsor
- Astellas Pharma Inc
Bipolar Disorder, Major Depressive Disorder
Pregnenolone Trial for Depression in Bipolar Disorders or Recurrent Major Depressive Disorder With Substance Abuse
The purpose of this research is to determine if pregnenolone supplement is associated with a reduction in substance use and craving in patients with recurrent major depressive disorder or bipolar disorder and substance…
- Conditions
- Bipolar Disorder, Major Depressive Disorder, Substance Abuse
- Trial name
- NCT00223197
- Testing
- Pregnenolone
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- University of Texas Southwestern Medical Center
Thyroidectomy
LigaSure vs Bipolar Diathermy in Thyroidectomy
Comparative Evaluation of LigaSure Versus Conventional Bipolar Diathermy in Thyroid Surgery: Operative and Postoperative Outcome.
- Trial name
- NCT07274891
- Testing
- LigaSure, bipolar diathermy, Thyroidectomy
- Volunteers
- 30 people
- Sponsor
- Assiut University
Stress Disorders, Traumatic, Depressive Disorder
The Immune System and Psychiatric Disorders
The study is based on a hypothesis that there is interaction between the activity in the immune system and in the mind. To study this, the investigators register different measures for activity in the immune system on patients…
- Conditions
- Stress Disorders, Traumatic, Depressive Disorder, Bipolar Disorder, Personality Disorders
- Trial name
- NCT00184418
- Where
- Norway
- Volunteers
- 1,400 people
- Sponsor
- Norwegian University of Science and Technology
Depression, Major Depressive Episode
Study Comparing Magnetic Seizure Therapy (MST) to Electroconvulsive Therapy (ECT) for Depression in Older Adults
To evaluate the feasibility, tolerability and efficacy of Magnetic Seizure Therapy (MST) in elderly patients with a major depressive episode, who are randomly assigned to receive an acute course of MST or ECT.
- Conditions
- Depression, Major Depressive Episode, Bipolar Disorder
- Trial name
- MSTvsEST (NCT01869374)
- Testing
- MagVenture MagPro MST, RUL ECT
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- New York State Psychiatric Institute
Bipolar Disorder
Predictors of Recurrence in Bipolar Disorder in Spain
Observational, prospective (1 year follow up), multicenter, non-interventional open label study in order to assess the factors that predict onset of mood disorders episodes (depression, mania, hypomania and mixed) in stabilized…
- Trial name
- PREBIS (NCT00690859)
- Where
- 49 sites in Spain
- Volunteers
- 595 people
- Sponsor
- AstraZeneca
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