Clinical trials: bipolar
Schizophrenia, Psychosis
Enhancing Rehabilitation for Veterans With Serious Mental Illness
This study addresses the critical need for innovative therapeutic interventions in Veterans with serious mental illnesses (SMI) receiving care in VA Psychosocial Rehabilitation and Recovery Centers (PRRCs).
- Conditions
- Schizophrenia, Psychosis, Serious Mental Illness, PTSD
- Trial name
- NCT06586164
- Testing
- Targeted Cognitive Training
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- VA Office of Research and Development
Bipolar Disorder
Daily Subjective and Objective Smartphone Measures of Illness Activity to Treat Bipolar Disorder- The MONARCA II Trial
Bipolar disorder is associated with a high risk of relapse and hospitalisation and many patients do not recover to their previous psychosocial function.
- Trial name
- MONARCAII (NCT02221336)
- Testing
- The MONARCA II system, Non-MONARCA II system
- Where
- Denmark
- Volunteers
- 146 people
- Sponsor
- Psychiatric Centre Rigshospitalet
Skin Laxity
Clinical Assessment of Skin Tightening and Contour Change of Submental Tissue Using Bipolar Radiofrequency Microneedling
The purpose of this study is to evaluate the safety and efficacy of bipolar fractional radiofrequency treatment via use of the Profound System to achieve skin tightening and contour change in lax submental (beneath the chin)…
- Trial name
- NCT04477187
- Testing
- Dermal Handpiece
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Healthy, Bipolar Disorder
Brain Ion Homeostasis, Lithium and Bipolar Disorder
In this project, investigators intend to carry out the first simultaneous, in vivo, imaging study of lithium content and sodium ion homeostasis in the brain of Bipolar Disorder (BPD) patients under Lithium therapy.
- Trial name
- NCT02727127
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Bipolar Disorder
Culturally Adapted Psychoeducation (CaPE) for Bipolar Disorders in Nigeria
Bipolar disorders are chronic mental health disorders that often result in functional impairment, constituting a significant disease burden.
- Trial name
- NCT05721196
- Testing
- Culturally adapted Psychoeducation (CaPE), Treatment as Usual (TaU)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Nottingham Trent University
Depressive Disorder, Major, Bipolar Depression
Triple Chronotherapy in Adolescents
Study Purpose This study is a randomized controlled trial examining the effectiveness of TCT in the acute treatment of depression and suicidality in adolescents compared to usual treatment care, which includes individual and…
- Conditions
- Depressive Disorder, Major, Bipolar Depression, Suicidal Ideation
- Trial name
- TCT-RCT (NCT03679962)
- Testing
- Triple Chronotherapy, Treatment as Usual
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Billings Clinic
Bipolar Disorder
Geodon in Weight Loss Study for Bipolar Disorders
This research study is designed to determine if replacing your current antipsychotic and/or mood stabilizer with ziprasidone (Geodon) will impact weight.
- Trial name
- NCT00472641
- Testing
- Ziprasidone/Geodon
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Stanford University
Bipolar Disorder
Combination Therapy in Dual Diagnosis Bipolar Rapid Cycling
Combination Therapy in Dual Diagnosis Bipolar Rapid Cycling: This study recruits males and females age 18 and older who currently meet diagnostic criteria for rapid cycling bipolar disorder (type I or II) and who have met the…
- Trial name
- NCT00221975
- Testing
- Divalproex, Lamotrigine, Lithium
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Prostatic Hyperplasia, Lower Urinary Tract Symptoms
Hydrodissection-Assisted Bipolar Prostatic Enucleation Versus Conventional Bipolar Enucleation
This prospective randomized study will compare two surgical techniques for treating benign prostatic hyperplasia. Participants will be assigned to either hydrodissection-assisted bipolar prostatic enucleation-enucleoresection…
- Trial name
- NCT07749794
- Testing
- Hydrodissection-Assisted Bipolar Prostatic Enucleation-Enucleoresection, Conventional Bipolar Prostatic Enucleation-Enucleoresection
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Benha University
Bipolar Disorder, Tobacco Use Disorder
A Future Thinking Intervention for Comorbid Tobacco Use Disorder and Bipolar Disorder
Future Self-BD is a 6-session virtual intervention that encourages participants to vividly generate personal and positive future events that they anticipate may be benefited by smoking cessation.
- Trial name
- NCT06609902
- Testing
- Future Self-BD, Daily Check-Ins
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Massachusetts General Hospital
Menorrhagia
Hyaluronic Acid Gel in Prevention of Intrauterine Adhesions After Endometrial Ablation
The aim of the study is to evaluate if hyaluronic acid gel prevents intrauterine adhesion formation after endometrial thermal ablation.
- Trial name
- NCT01829451
- Testing
- Hyaluronic acid gel
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Oulu
Prosthetic-joint Infection
Incidence of Early Infection After Bipolar Hemiarthroplasty and Its Associated Factors in Fracture Neck of Femur
Periprosthetic joint infections (PJI) following hemiarthroplasty for hip fractures are a catastrophic complication that results in severe worsening of patients' daily function and quality of life.
- Trial name
- NCT06427772
- Testing
- bipolar hemiarthroplasty
- Volunteers
- 74 people
- Sponsor
- Assiut University
Bipolar Disorder
Radiosurgical Neuromodulation for Refractory Depression
This study is designed to evaluate the safety and effectiveness of an investigational procedure for treating people with treatment resistant bipolar depression (TRD).
- Trial name
- NCT01403441
- Testing
- Radiosurgical Neuromodulation using the Cyberknife
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Stanford University
Bipolar Disorder
Evaluating the Effectiveness of Imagery Focussed Therapy
This study explores the effectiveness of a brief Imagery-focussed Cognitive Therapy (imCT) compared to psychoeducation, regarded as treatment as usual for this patient population, in patients suffering from BD receiving mood…
- Trial name
- NCT03750305
- Testing
- imagery-focused Cognitive Therapy, TAU
- Where
- Netherlands
- Volunteers
- 62 people
- Sponsor
- Maastricht University
Bipolar Disorder
Family Workshops for Bipolar Disorder
This pilot study is looking at the effects of a brief psychoeducational workshop. These one day workshops are designed to increase family members knowledge about bipolar disorder and to help with processing emotions that go along…
- Trial name
- NCT00296283
- Testing
- integrative behavior couples therapy
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Miami
Bipolar Disorder
Functional Remediation for Older Adults With Bipolar Disorder
Bipolar Disorder (BD) is a chronic and severe mental illness characterized by the emergence of alternating mood episodes which range from extreme depression to manic states.
- Trial name
- FROA-BD (NCT05186337)
- Testing
- FROA-BD programme
- Where
- Spain
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Consorcio Centro de Investigación Biomédica en Red (CIBER)
Castration-Resistant Prostate Carcinoma, Prostate Adenocarcinoma
Testosterone and Olaparib in Treating Patients With Castration-Resistant Prostate Cancer
This phase II trial studies how well testosterone (enanthate or cypionate) and olaparib work in treating patients with prostate cancer that has progressed despite hormonal therapy.
- Trial name
- NCT03516812
- Testing
- Laboratory Biomarker Analysis, Olaparib, Quality-of-Life Assessment
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Washington
Bipolar Disorder, Schizophrenia
A Non-Interventional Post-Marketing Surveillance Study to Evaluate the Safety and Efficacy of Zeldox Capsule
This is a regulatory-required non-interventional pharmacovigilance study exploring the safety profile of ziprasidone HCL monohydrate 20mg, 40mg, 60mg, 80mg in the real world patient population, thus, safety (and/or efficacy)…
- Trial name
- NCT01053429
- Testing
- ziprasidone
- Volunteers
- 3,391 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Schizophrenia, Schizoaffective Disorder
Magnesium Variations and Cardiometabolic Risk in Patients With Antipsychotic Drugs
Background: Antipsychotics can induce metabolic disorders such as obesity, hyperglycemia, dyslipidemia or metabolic syndrome. It has been observed that treatment with antipsychotic could be accompanied by a decrease in the…
- Conditions
- Schizophrenia, Schizoaffective Disorder, Bipolar Disorder
- Trial name
- NCT02986490
- Testing
- Blood sample
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Montpellier
Bipolar Disorder, Early Intervention
Early Assessment and Intervention for Adolescents at Risk for Bipolar Disorder
Bipolar disorder is a severe and chronic illness associated with significant occupational and social impairment, enormous public health costs, and high rates of suicide.
- Trial name
- NCT03203707
- Testing
- Interpersonal and Social Rhythm Therapy
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Pittsburgh
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.