Clinical trials: bipolar
Depressive Disorder, Treatment-Resistant, Depressive Disorder, Major
Music as an Intervention to Improve Hemodynamic Tolerability of Ketamine in Depression
The purpose of this study is to assess the impact of music on patients receiving a course of intravenous (IV) ketamine for treatment-resistant depression (TRD), both unipolar and bipolar.
- Conditions
- Depressive Disorder, Treatment-Resistant, Depressive Disorder, Major, Unipolar Depression, Depression, Bipolar
- Trial name
- NCT04701866
- Testing
- Music
- Where
- 2 sites in Canada
- Volunteers
- 32 people
- Sponsor
- Douglas Mental Health University Institute
Severe Mental Illness, Bipolar Disorder
A Mobile App to Support Mood, Daily Routines and Medication Adherence in Adults With Severe Mental Illness
The goal of this clinical trial is to learn whether MoodSync, a mobile application for patients and their family caregivers, improves mood stability, medication adherence, daily functioning and early detection of relapse warning…
- Conditions
- Severe Mental Illness, Bipolar Disorder, Schizophrenia, Schizoaffective Disorder
- Trial name
- MoodSync (NCT07879131)
- Testing
- MoodSync, Standard care
- Where
- Bahrain
- Volunteers
- 60 people
- Sponsor
- Alexandria University
Anxiety State, Depression
Comparison of Physical and Virtual Sensory Room in an Inpatient Setting
Sensory room is a new method in psychiatric inpatient care for management of anxiety. Since this method for anxiety management is being implemented more and more extensively within the psychiatric care system it is important to…
- Conditions
- Anxiety State, Depression, Bipolar Depression
- Trial name
- NCT03918954
- Testing
- Virtual sensory room, Sensory room
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Vastra Gotaland Region
Bipolar Disorder
Evaluating the Effectiveness of Family-Focused Psychoeducation in Treating Adolescents With Bipolar Disorder
This study will evaluate the effectiveness of family-focused psychoeducational treatment along with medication in treating adolescents with bipolar I disorder.
- Trial name
- NCT00571402
- Testing
- Family-focused therapy for adolescents, Enhanced care
- Where
- 2 sites in United States
- Volunteers
- 58 people
- Sponsor
- University of California, Los Angeles
PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries, Depression, Anxiety
Research on Risk Factors and Interventions of Polycystic Ovary Syndrome Complicated With Depression and Anxiety
The current study intends to establish a prediction method and evaluation system for polycystic ovary syndrome (PCOS) complicated with affective disorder, such as depression and anxiety, through the epidemiological investigation.
- Trial name
- PCOS (NCT04984070)
- Testing
- Oral Contraceptives, Combined, Metformin Pill, lifestyle intervention
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Fudan University
Bipolar Disorder
Cost- Effectiveness and Quality of Life Assessment in Mood Disorder
To evaluate the effectiveness of three systematic interventions for Bipolar Disorder (BD) mixed episodes using medications available in the Brazilian Public Healthcare System (SUS), and assessment of the quality of life of these…
- Trial name
- NCT02870283
- Testing
- Lithium, Valproic Acid, Carbamazepine
- Volunteers
- 107 people
- Sponsor
- Federal University of Rio Grande do Sul
Bipolar I Disorder
A Multicenter, Placebo-controlled, Double-blind Investigative Extension Trial of the Safety and Efficacy of Aripiprazole in the Treatment of Patients With Bipolar Disorder Experiencing a Manic or Mixed Episode
To investigate the safety and efficacy of long-term administration of aripiprazole by performing extended administration of the treatment administered in the preceding multicenter, double-blind, placebo-controlled, parallel…
- Trial name
- NCT00606177
- Testing
- Aripiprazole
- Where
- 12 sites in China, Japan and 2 more
- Volunteers
- 99 people
- Sponsor
- Otsuka Pharmaceutical Co., Ltd.
Bipolar I Disorder
The Young Adult and Pediatric Bipolar Study
To examine the safety and effectiveness of extended-release carbamazepine in the treatment of children and adolescents aged 10-17 years with acute manic or mixed bipolar I disorder.
- Trial name
- NCT00350857
- Testing
- Extended-Release Carbamazepine
- Where
- 26 sites in United States
- Volunteers
- 161 people
- Sponsor
- Validus Pharmaceuticals
Bipolar Affective Disorders
Chemokine Receptors on CD8+ T Cells in Patients With Bipolar Disorder
This observational study investigates the expression profile of chemokine receptors and adhesion molecules in CD8+ T lymphocytes from individuals with Bipolar Disorder compared with healthy controls.
- Trial name
- SPERLIC (NCT07785167)
- Testing
- CD8+ T-Cell Gene Expression Analysis
- Where
- Italy
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- University of Catania
Osteoarthritis, Arthritis
Bipolar Sealer Aquamantys Use in Total Knee Replacement
This study will compare the clinical outcomes for patients undergoing a total knee replacement using a bipolar sealer, the Aquamantys® System, as compared to standard electrocautery.
- Conditions
- Osteoarthritis, Arthritis, Surgery, Infection
- Trial name
- NCT01736644
- Testing
- Electrocautery, Bipolar sealer Aquamantys
- Where
- 2 sites in United Kingdom
- Volunteers
- 97 people
- Sponsor
- Medtronic Surgical Technologies
Bipolar Disorder
SOLMANIA - Comparison of Valproate-Amisulpride and Valproate-Haloperidol in Bipolar I Patients
The primary objective is: To compare the efficacy of the association valproate-amisulpride (400 to 800 mg/day) to the association valproate-haloperidol (5 to 15 mg/day) in bipolar I patients suffering from a manic episode…
- Trial name
- NCT00126009
- Testing
- Amisulpride
- Where
- 5 sites in Czechia, France and 3 more
- Volunteers
- 120 people
- Sponsor
- Sanofi
Psychosis
Focus Groups on Cognitive Function in Psychosis
Cognitive deficits are commonly observed in people with mental disorders. In psychosis, these impairments are frequently present early in the course of the disorder and have a substantial impact on functional outcomes.
- Trial name
- PRECOGNITION (NCT06364241)
- Testing
- Focus group
- Volunteers
- 32 people
- Sponsor
- King's College London
Schizophrenia, Bipolar Disorder
Emotional Eating, Sleep Quality, Mental State and Metabolic Syndrome
In predominantly medication-naïve schizophrenic patients, those exhibiting partial metabolic disorders have significantly worse sleep quality and sleep onset time; poor sleep predicted metabolic dysregulation even after…
- Conditions
- Schizophrenia, Bipolar Disorder, Psychiatric Issue, Metabolic Syndrome
- Trial name
- NCT07411222
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Abant Izzet Baysal University
Bipolar I Disorder, Schizophrenia
Long-term Safety Extension Study of OLZ/SAM in Pediatric Subjects
To evaluate the long-term safety and tolerability of OLZ/SAM in pediatric subjects with schizophrenia or Bipolar I disorder
- Trial name
- NCT04987229
- Testing
- OLZ/SAM
- Where
- 35 sites in United States, Argentina and 3 more
- Volunteers
- 236 people
- Sponsor
- Alkermes, Inc.
Diabetes, Asthma
Integrated Care (IC) Models for Patient-Centered Outcomes
Multiple chronic conditions (MCC) are widely recognized as the U.S. public health challenge of the 21st century. These physical and behavioral health conditions take a large toll on those living with chronic diseases, including…
- Conditions
- Diabetes, Asthma, Chronic Obstructive Pulmonary Disease, Hypertension
- Trial name
- IC (NCT03451630)
- Testing
- High-Touch, High-Tech, Optimal Discharge Planning
- Where
- United States
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Schizophrenia, Bipolar I Disorder
A Trial of Single- and Multiple-doses of Aripiprazole in Adult Subjects With Schizophrenia or Bipolar I Disorder
The primary objective of this trial is to evaluate the pharmacokinetics (PK) of aripiprazole long-acting injectable (LAI) (420 mg) following deltoid or gluteal muscle administration in adult subjects with schizophrenia or bipolar…
- Trial name
- NCT03854409
- Testing
- Aripiprazole
- Where
- 4 sites in United States
- Volunteers
- 72 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Bipolar I Disorder, Manic Episode
A Trial to Assess Brexpiprazole Versus Placebo for the Treatment of Acute Manic Episodes Associated With Bipolar I Disorder
To demonstrate the efficacy of brexpiprazole for the acute treatment of manic episodes, with or without mixed features, in participants with a diagnosis of bipolar I disorder.
- Trial name
- NCT03259555
- Testing
- Brexpiprazole
- Where
- 48 sites in United States, Bulgaria and 2 more
- Volunteers
- 322 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Insomnia, Bipolar Disorder
Efficacy of Suvorexant to Treat Insomnia Related to Bipolar Disorder
The purpose of this study is to evaluate the efficacy of suvorexant, added to existing medications, for treatment-resistant insomnia in individuals with bipolar disorder.
- Trial name
- NCT02527564
- Testing
- Suvorexant
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Stanford University
Depression, Anxiety Disorders
Focused Ultrasound Amygdala Neuromodulation
The purpose of the study is to examine the feasibility and potential efficacy of low-intensity focused ultrasound as a method of modulating amygdala function to promote improvements in symptoms of an affective disorder.
- Conditions
- Depression, Anxiety Disorders, Bipolar Depression, Ptsd
- Trial name
- NCT05228964
- Testing
- Focused ultrasound
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Bipolar Disorder, Bipolar Depression
Vitamin D Supplementation for Bipolar Depression
The purpose of this study is to whether vitamin d supplementation in those with low levels may reduce depression symptoms in people experiencing bipolar depression.
- Trial name
- NCT01884844
- Testing
- Vitamin D3, Cholecalciferol
- Where
- 2 sites in United States
- Volunteers
- 33 people
- Sponsor
- University of Massachusetts, Worcester
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.