Clinical trials: bipolar
Bipolar Disorder, Bipolar I Disorder
Emotional Proactive Processing in Bipolar Disorder
The main objective of this project is to identify behavioral specificities of the proactive emotional brain among bipolar patients, compared to healthy subjects.
- Conditions
- Bipolar Disorder, Bipolar I Disorder, Bipolar II Disorder
- Trial name
- PROEMO_BP (NCT04561622)
- Testing
- Emotional Stroop Task
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Bipolar Disorder
The Effect of Omega-3 Polyunsaturated Fatty Acids in the Treatment and Prevention of Relapse of Bipolar Disorder
The whole study will be divided into two major parts: (A) A 12-week, double-blind, randomized controlled, parallel n-3 fatty acids adjunctive therapy study in 30 bipolar disorder patients with mild to moderate depression.
- Trial name
- NCT01371383
- Testing
- n-3 fatty acids
- Where
- Taiwan
- Volunteers
- 61 people
- Sponsor
- National Science and Technology Council, Taiwan
Pediatric Bipolar Disorder, Pediatric OCD
Fluoxetine for Obsessive-Compulsive Disorder in Children and Adolescents With Bipolar Disorder
This will be a 12-week open-label pilot treatment study for children and adolescents (ages 6-17) who meet DSM-IV criteria for bipolar disorder (BPD) and obsessive-compulsive disorder (OCD) who are adequately mood stabilized on a…
- Trial name
- NCT00592852
- Testing
- fluoxetine
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Massachusetts General Hospital
Bipolar I Disorder
Phase 1 Study of OLZ/SAM in Pediatric Subjects With Bipolar I Disorder
To evaluate the safety, tolerability, and pharmacokinetics of olanzapine and samidorphan in clinically stable pediatric subjects (10 to 12 years old) with Bipolar I disorder following oral administration of multiple ascending…
- Trial name
- NCT04987658
- Testing
- OLZ/SAM
- Where
- 2 sites in United States
- Volunteers
- 7 people
- Sponsor
- Alkermes, Inc.
Bipolar Disorder
Clozapine for Treatment-Resistant Mania
The purpose of this study is to evaluate the safety and effectiveness of clozapine as a treatment for the manic phase of bipolar disorder.
- Trial name
- NCT00029458
- Testing
- Clozapine
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- National Institute of Mental Health (NIMH)
PSA Changes After TURP
Serum Prostatic Specific Antigen Changes After Bipolar and Monopolar TURP
To use PSA levels after bipolar and monopolar transurethral resection of the benign prostatic hyperplasia as an indicator of the quality of resection .
- Trial name
- NCT05533047
- Testing
- TURP
- Volunteers
- 2 people
- Sponsor
- Assiut University
Bipolar Disorders
Series Studies of Bipolar Disorder-Valproate add-on Memantine
All participants should fulfill the following criteria: aged between 18 and 65 years old, and of domestic Han descendants. Participants will be randomly assigned to either the (1) pharmacotherapy (valproate add-on memantine)…
- Trial name
- MM (NCT01188148)
- Testing
- Memantine
- Where
- Taiwan
- Volunteers
- 219 people
- Sponsor
- National Cheng-Kung University Hospital
Schizophrenia, Bipolar Disorder
Contingency Management for Problematic Behavior Reduction in the Community
This study aims to determine the feasibility and effectiveness of implementing a contingency management program in a small group of mentally ill, unhoused individuals with schizophrenia or bipolar disorder and anosognosia (a lack…
- Conditions
- Schizophrenia, Bipolar Disorder, Anosognosia
- Trial name
- NCT06486584
- Testing
- Contingency Management
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Laureate Institute for Brain Research, Inc.
Attention Deficit Hyperactivity Disorder
Neuroimaging Study of Risk Factors for Adolescent Bipolar Disorder
The main purpose of this study is to see the affects of the study medication called mixed amphetamine salts-extended release (MAS-XR) on brain function by taking brain pictures.
- Trial name
- NERF (NCT02478788)
- Testing
- mixed amphetamine salts-extended release (MAS-XR)
- Where
- United States
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Bipolar Disorder, Insulin Resistance
Pioglitazone for the Treatment of Bipolar Depression
The primary objective is to test the hypothesis that adjunctive pioglitazone is more effective than placebo for the relief of acute depressive symptoms resulting from bipolar disorder.
- Trial name
- NCT01717040
- Testing
- Pioglitazone
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- University Hospitals Cleveland Medical Center
Prescription
The Third Survey of Prescription Pattern of Psychotropic Drugs in China
The investigators aimed to examine the psychotropic prescription pattern in China.
- Trial name
- NCT01668810
- Where
- China
- Volunteers
- 7,000 people
- Sponsor
- Peking University
Bipolar Disorder
Effect of Quetiapine on Sleep Architecture in Bipolar Depression and Major Depressive Disorder
Clinical practice indicates that Quetiapine has sedating properties, and its sedative effects may play an important role in restoring quality of sleep in patients with various psychiatric conditions who frequently experience…
- Trial name
- NCT00616889
- Testing
- Seroquel
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- Queen's University
Postoperative Atrial Fibrillation
Bipolar Radiofrequency Ablation -Role in Prevention of Postoperative Atrial Fibrillation
Atrial Fibrillation (AF) is one of the most common postoperative complications after coronary artery bypass grafting (CABG). Postoperative AF produces a substantial impact on hospital resources with an estimated annual…
- Trial name
- NCT00765089
- Testing
- Isolation of pulmonary veins with Bipolar radiofrequency ablation
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Pittsburgh
Schizophrenia, Bipolar Disorder
Joint Crisis Plans or Crisis Cards for People With Severe Mental Disorders to Reduce Coercion in Psychiatric Care.
This randomized clinical trial compares the influence of joint crisis plans (JCP) or crisis cards to reduce psychiatric coercion for people with severe and often recurring mental illnesses like schizophrenia, bipolar disorder or…
- Conditions
- Schizophrenia, Bipolar Disorder, Schizoaffective Disorder
- Trial name
- JCPUKE (NCT03240380)
- Testing
- joint crisis plan, crisis card
- Where
- Germany
- Volunteers
- 374 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Depression, Bipolar Disorder
Bupropion SR for Major Depression and Depression NOS in Children and Adolescents With Bipolar Disorder
This is an 8-week open label study of bupropion SR in the treatment of youth with bipolar depression with adequate mood stabilization.
- Trial name
- NCT00181896
- Testing
- bupropion SR
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Massachusetts General Hospital
Schizophrenia, Bipolar Episodes
Description of the Use of Quetiapine Extended Release (XR) in Real-life Practice in France. An Observational Study
The aim of the study is to describe patient characteristics (demographic and clinical) and the patterns of use of Quetiapine XR in patients receiving the drug for the first time in real-life practice regardless the final…
- Trial name
- NCT01689389
- Where
- 19 sites in France
- Volunteers
- 2,292 people
- Sponsor
- AstraZeneca
Bipolar Disorder, Psychiatric Morbidity
Bipolar Disorder in Pregnancy and the Postpartum Period: Predictors of Morbidity
The purpose of this study is to examine risk factors for relapse of bipolar disorder during pregnancy and the postpartum period.
- Conditions
- Bipolar Disorder, Psychiatric Morbidity, Neonatal Outcome
- Trial name
- NCT00580268
- Where
- 2 sites in United States
- Volunteers
- 118 people
- Sponsor
- Massachusetts General Hospital
Metastatic Castration-resistant Prostate Cancer
The COSMYC Trial (COmbined Suppression of MYC)
This research is being done to determine if receiving the combination of testosterone and ZEN-3694 followed by the combination of enzalutamide plus ZEN-3694 will decrease the size of tumors in patients with prostate cancer that…
- Trial name
- NCT06922318
- Testing
- ZEN-3694, Testosterone cypionate, Enzalutamide
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Mood Disorder
Studies of Brain Function and Course of Illness in Pediatric Bipolar Disorder
This study seeks to learn more about the symptoms of severe mood dysregulation in children and adolescents ages 7-17. Children and adolescents with severe mood dysregulation (SMD) display chronic anger, sadness, or irritability…
- Trial name
- NCT00025935
- Testing
- Lithium
- Where
- United States
- Volunteers
- 2,350 people
- Sponsor
- National Institute of Mental Health (NIMH)
Bipolar 1 Disorder, Schizophrenia Disorder
An Expanded Access Program (EAP) for OLZ/SAM in Pediatric Participants With Schizophrenia or Bipolar I Disorder (ALKS 3831-315)
To provide continued access to OLZ/SAM for pediatric participants with schizophrenia or bipolar I disorder who have completed participation in the ALKS 3831-A313 long-term safety extension study.
- Trial name
- NCT07744113
- Testing
- OLZ/SAM
- Where
- United States
- Sponsor
- Alkermes, Inc.
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