Clinical trials: copd or chronic obstructive
Chronic Obstructive Pulmonary Disease
ADL- Training for Patients With Chronic Obstructive Pulmonary Disease (COPD)
ADL training of copd patients results in better execution of activities of daily living.
- Trial name
- NCT00887705
- Testing
- ADL training
- Where
- 2 sites in Norway
- Volunteers
- 24 people
- Sponsor
- LHL Helse
HIV, COPD
Copenhagen Comorbidity in HIV Infection Study
Despite efficient antiretroviral treatment for HIV infection, decrease in life expectancy remains. Excess mortality is mainly due to non-AIDS co-morbidity including cardiovascular, pulmonary, and liver related diseases.
- Conditions
- HIV, COPD, CVD, Liver Disease
- Trial name
- COCOMO (NCT02382822)
- Testing
- No intervention.
- Where
- 2 sites in Denmark
- Volunteers
- 1,099 people
- Sponsor
- Susanne Dam Nielsen, MD, DMSc
Chronic Obstructive Pulmonary Disease (COPD)
Investigation of the Acute Effects of Traditional and Functional IMT on Muscle Oxygenation in COPD
This study aims to compare the effects of functional and conventional inspiratory muscle training (IMT) on post-exercise muscle deoxygenation in individuals with Chronic Obstructive Pulmonary Disease (COPD).
- Trial name
- NCT07267923
- Testing
- Traditional inspiratory muscle training, Functional inspiratory muscle training (IMT)
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Saglik Bilimleri Universitesi
Pulmonary Disease, Chronic Obstructive, Tobacco Smoking
COPD E-cigarette Topography Training
This study is for people with chronic obstructive pulmonary disease (COPD) and who smoke. Investigators are trying to find out if training on e-cigarette use will help smokers switch to e-cigarettes.
- Trial name
- NCT05510154
- Testing
- Brief advice, Single Training, Training to Competency
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Chronic Obstructive Pulmonary Disease
Imaging Progression of Chronic Obstructive Pulmonary Disease Using MRI and CT (MR-COPDII)
In this follow-up trial, MRI and CT images of the lung will be acquired prospectively in a subcohort of 370 patients, three years after they successfully participated in the first COSYCONET subtrial with CT and MRI ("MR-COPD I"…
- Trial name
- MR-COPDII (NCT03591562)
- Where
- 10 sites in Germany
- Volunteers
- 252 people
- Sponsor
- University Hospital Heidelberg
Infections, Heart Failure
Rural Hospital-Level Care at Home for Acutely Ill Adults
This study examines the implications of providing hospital-level care in rural homes.
- Conditions
- Infections, Heart Failure, Chronic Obstructive Pulmonary Disease, Asthma
- Trial name
- NCT05256303
- Testing
- Home Hospital care, Traditional Hospital care
- Where
- 3 sites in United States, Canada
- Volunteers
- 160 people
- Sponsor
- Brigham and Women's Hospital
COPD, Non-invasive Ventilation
Effect of Noninvasive High Frequency Oscillatory Ventilation on Improving Carbon Dioxide Clearance in AECOPD Patients
High-frequency oscillatory ventilation (HFOV), as an ideal lung-protecting ventilation method, has been gradually used in neonatal critical care treatment, and is currently recommended as a rescue method for neonatal acute…
- Trial name
- NCT05435183
- Testing
- Non-invasive high-frequency oscillatory ventilation, Noninvasive Bilevel Positive Pressure Ventilation
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Guangzhou Institute of Respiratory Disease
COPD
A Dose-Range Finding Study of SUN-101 in Subjects With Moderate to Severe COPD
Study for subjects 40 to 65 years-old with a diagnosis of moderate to severe COPD. Aclidinium bromide 400 mcg 2x a day will be given as an active comparator.
- Trial name
- GOLDEN 6 (NCT02038829)
- Testing
- SUN101 3 mcg, SUN-101 6.25 mcg, SUN-101 12.5 mcg
- Where
- 10 sites in United States
- Volunteers
- 96 people
- Sponsor
- Sunovion Respiratory Development Inc.
Congestive Heart Failure, Cancer
Team-based Versus Primary Care Clinician-led Advance Care Planning in Practice-based Research Networks
This project compares two models of the Serious Illness Care Program (SICP) in primary care: clinician-focused SICP and team-based SICP.
- Conditions
- Congestive Heart Failure, Cancer, Chronic Obstructive Pulmonary Disease, Cerebrovascular Accident
- Trial name
- NCT03577002
- Testing
- Serious Illness Care Program (SICP)
- Where
- 7 sites in United States, Canada
- Volunteers
- 1,120 people
- Sponsor
- Oregon Health and Science University
Chronic Obstructive Pulmonary Disease
Effect on Adrenal Function of Budesonide Versus Fluticasone in Chronic Obstructive Pulmonary Disease (COPD)
National Institute for Clinical Excellence (NICE) guidelines recommend high dose inhaled steroids for patients with moderate to severe Chronic Obstructive Pulmonary Disease (COPD, a common chronic disease related to smoking) who…
- Trial name
- NCT01186653
- Testing
- budesonide / formoterol, fluticasone/salmeterol
- Where
- United Kingdom
- Volunteers
- 22 people
- Sponsor
- Hull University Teaching Hospitals NHS Trust
Chronic Obstructive Pulmonary Disease, Lung Cancer
Accelerated Pulmonary Rehabilitation in the Preoperative Period
This proposed project will be a single arm, non-masked study. Participants who are actively smoking with a diagnosis of a new lung nodule, either confirmed or suspicious for lung cancer, with a plan for lung cancer treatment with…
- Trial name
- PREHAB (NCT06432972)
- Testing
- Pulmonary Rehab
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Vermont
Chronic Obstructive Pulmonary Disease
Molecular Signatures Associated With Response to ICS Treatment in Patients With COPD Stratified by Eosinophil Levels
The 3TR-ICS COPD study is an international, multicentre, randomized, parallel, controlled study that will recruit clinically stable former smokers COPD patients (with no exacerbations in the previous 8 weeks) on treatment with…
- Trial name
- 3TR-ICS-COPD (NCT06334575)
- Testing
- Budesonide
- Where
- 6 sites in Germany, Netherlands and 2 more
- Volunteers
- 135 people
- Sponsor
- Maria Joyera Rodríguez
Atelectasis, Pulmonary Infection
Bi-PAP vs Sham Bi-PAP on Pulmonary Function in Morbidly Obese Patients After Bariatric Surgery
The effect of biphasic positive airway pressure (Bi-PAP) at individualized pressures on the postoperative pulmonary recovery of morbidly obese patients (MOP) undergoing open bariatric surgery (OBS) and possible placebo…
- Conditions
- Atelectasis, Pulmonary Infection, Chronic Obstructive Pulmonary Disease (COPD), Pulmonary Disease
- Trial name
- NCT03438383
- Testing
- Bi-PAP
- Volunteers
- 48 people
- Sponsor
- Evangelismos Hospital
Hepatitis C Virus (HCV)
A Study of of Glecaprevir/Pibrentasvir in Adults With Chronic Hepatitis C Virus (HCV) Genotype 5 or 6 Infection
A Phase 3b, open-label, multicenter study to evaluate the efficacy and safety of glecaprevir/pibrentasvir for an 8- or 12-week treatment duration in participants with chronic hepatitis C virus (HCV) genotype (GT) 5 or 6…
- Trial name
- ENDURANCE-5 6 (NCT02966795)
- Testing
- Glecaprevir/Pibrentasvir
- Where
- 25 sites in United States, Australia and 7 more
- Volunteers
- 84 people
- Sponsor
- AbbVie
Chronic Obstructive Pulmonary Disease (COPD)
A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00006)
A Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel Group, Phase 3 Study to Evaluate the Efficacy and Safety of Tezepelumab in Adults with Moderate to Very Severe Chronic Obstructive Pulmonary Disease (COPD)
- Trial name
- EMBARK (NCT06883305)
- Testing
- Tezepelumab
- Where
- 305 sites in United States, Brazil and 16 more
- Volunteers
- 990 people
- Sponsor
- AstraZeneca
Chronic Obstructive Pulmonary Disease
Detection of Aspergillus Fumigatus and Sensitization in COPD Patients With Bronchiectasis vs Without Bronchiectasis
A single center case-control study with 100 COPD patients will be organized to compare patients with and without bronchiectasis with regard to the presence of Aspergillus in sputum samples, Aspergillus sensitization and vitamin…
- Trial name
- NCT02332122
- Testing
- Sputum induction, Skin prick test, Questionnaires
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Wim Janssens
COPD, Chronic Lung Disease
A Clinical Evaluation of the Oxitone Non-invasive Oximeter
The trial shall assess the accuracy of the Oxitone® 1000 in measuring oxygen saturation, by comparing its measurement to reference devices: non-invasive SpO2 and pulse-rate values determined by a pulse oximeter.
- Trial name
- CPOM (NCT02658045)
- Testing
- Standard Oximeter, Oxitone oximeter
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Asthma, COPD
SADT in COPD and Oscillometry in Obstructive Airway Disease in Primary Care. The SCOOP-study
Rationale: The Small Airways are a major site of obstruction in many respiratory diseases, including COPD. More insight into a diagnosis of Small Airways Dysfunction (SAD) in patients with COPD is clinically valuable as it might…
- Conditions
- Asthma, COPD, Small Airway Disease
- Trial name
- SCOOP (NCT07374172)
- Testing
- Oscillometer ALDS
- Where
- Netherlands
- Volunteers
- 108 people
- Sponsor
- General Practitioners Research Institute
Chronic Obstructive Pulmonary Disease Moderate
Mesenchymal Stem Cells for The Treatment of Chronic Obstructive Pulmonary Disease
The clinical study with UMC119-06 is designed to investigate the safety in patients with Chronic Obstructive Pulmonary Disease. This will be a dose escalation, open label, single-center study in adult with chronic obstructive…
- Trial name
- NCT04206007
- Testing
- UMC119-06
- Where
- Taiwan
- Volunteers
- 9 people
- Sponsor
- Meridigen Biotech Co., Ltd.
Chronic Pain, Chronic Pain Syndrome
Collaboratory Treatment Pathway for Chronic Pain Patients.
In this multicenter randomized controlled trial, the aim is to evaluate the effectiveness of a standardized treatment pathway (STP) for patients referred to four participating pain clinics, by comparing it to treatment as usual…
- Conditions
- Chronic Pain, Chronic Pain Syndrome, Chronic (Non-malignant) Musculoskeletal Pain, Patients Referred to Multidisciplinary Pain Clinics
- Trial name
- PainPath (NCT07331766)
- Testing
- A collaborative treatment pathway for patients referred to multidisciplinary pain clinics in Norway, Treatment as usual
- Where
- 4 sites in Norway
- Volunteers
- 386 people
- Sponsor
- St. Olavs Hospital
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