Clinical trials: copd or chronic obstructive
COPD, Obesity &Amp; Overweight
The Impact of a Weight Reduction Intervention on Clinical Outcomes in Patients With Obesity and COPD
Obesity and COPD are increasingly common and often coexist, worsening health outcomes such as reduced lung function, exercise capacity, and increased systemic inflammation.
- Trial name
- NCT07159594
- Testing
- Energy restriction
- Volunteers
- 70 people
- Sponsor
- Sahlgrenska University Hospital
COPD Exacerbation, Pulmonary Rehabilitation
Virtual Reality in COPD Exacerbation
In addition to conventional pulmonary rehabilitation, virtual reality will be applied during the hospitalization period of individuals hospitalized for COPD exacerbation.
- Trial name
- NCT05687396
- Testing
- virtual reality, conventional pulmonary rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Pamukkale University
COPD (Chronic Obstructive Pulmonary Disease)
Effect of Aronia Berry Consumption on Inflammatory Parameters
The study will aim to evaluate the effects of consuming freeze-dried aronia berries as an adjunct to medical treatment in patients with chronic obstructive pulmonary disease (COPD), focusing on anti-inflammatory, respiratory, and…
- Trial name
- NCT06702696
- Testing
- Black chokeberry (Aronia melanocarpa)
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Amasya University
Chronic Obstructive Pulmonary Disease
Evaluate the Safety of MN-221 in Subjects With Stable Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)
The objective of this clinical study is to determine the safety of intravenous MN-221 compared to placebo when administered in subjects diagnosed with stable moderate to severe COPD.
- Trial name
- NCT01013142
- Testing
- MN-221 (Dose Group 1), MN-221 (Dose Group 2), MN-221 (Dose Group 3)
- Where
- 7 sites in United States
- Volunteers
- 48 people
- Sponsor
- MediciNova
Chronic Obstructive Pulmonary Disease (COPD)
Investigating Senolytic Properties in Pulmonary Rehabilitation and Metformin in COPD Exacerbations
The purpose of this study is to investigate the safety and tolerability of Metformin and how it changes blood markers associated with aging in persons who have chronic obstructive pulmonary disease (COPD) who do not have diabetes.
- Trial name
- INSPIRE-COPD-E (NCT07275359)
- Testing
- Metformin
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Duke University
Pulmonary Disease, Chronic Obstructive
Determining Optimal Free Dose Combination of Tiotropium Bromide and BI 1744 CL in Chronic Obstructive Pulmonary Disease (COPD)
The primary objective of this study is to determine the optimum once daily dose of BI 1744 CL and tiotropium in free dose combination (delivered by the Respimat inhaler) after four week treatment in patients with COPD.
- Trial name
- NCT01040403
- Testing
- olodaterol (BI 1744) low, low tiotropium bromide, olodaterol (BI 1744) high
- Where
- 33 sites in Canada, Germany and 2 more
- Volunteers
- 233 people
- Sponsor
- Boehringer Ingelheim
Copd, Asthma
Strados System at Center of Excellence
Listening to breath sounds with the stethoscope/auscultation is used by pulmonary physicians in conjunction with pulmonary function, signs and symptoms, oxygen saturation and diagnostic testing to admit, follow and discharge…
- Conditions
- Copd, Asthma, Covid19
- Trial name
- NCT04485741
- Testing
- RESP
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Strados Labs, Inc.
Chronic Obstructive Pulmonary Disease (COPD)
A Study to Investigate the Pharmacokinetics, Safety and Tolerability of CHF 5993 pMDI in Subjects With Renal Impairment.
The study is performed to characterize the pharmacokinetics of glycopyrrolate bromide after single administration of CHF 5993 pressurised Metered Dose Inhaler (pMDI) in subjects with different level of renal impairment in…
- Trial name
- TRIPLE10 (NCT02040597)
- Testing
- Beclometasone/Formoterol/Glycopyrrolate
- Where
- 2 sites in Poland
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Chiesi Farmaceutici S.p.A.
COPD
MCID in 30 STS Test After PR in COPD Patients
The sit-to-stand test (STST) is a feasible alternative for measuring peripheral muscle strength of the lower limbs. Our aim was to evaluate, in Chronic Obstructive Pulmonary Disease (COPD) patients, the minimal clinically…
- Trial name
- COPD (NCT03627624)
- Testing
- Pulmonary rehabilitation
- Where
- 2 sites in Italy, Switzerland
- Volunteers
- 96 people
- Sponsor
- elisabetta zampogna
COPD
Singing for Wellness: Is Singing a Useful Way of Supporting People in South Devon to Self-manage Aspects of Their COPD
The aim of this study is to explore whether singing is a useful way of supporting people in South Devon to self manage aspects of their COPD and associated social isolation.
- Trial name
- NCT04360642
- Testing
- singing
- Where
- United Kingdom
- Volunteers
- 26 people
- Sponsor
- Torbay and South Devon NHS Foundation Trust
Pediatric Feeding Disorder, Chronic, Avoidant Restrictive Food Intake Disorder
The Use of Cyproheptadine in Pediatric Feeding Disorders
The goal of this clinical trial is to learn if Cyproheptadine, an appetite stimulant, can improve eating habits in children with Pediatric Feeding Disorders.
- Trial name
- NCT06751290
- Testing
- Cyproheptadine, Nutritional Counseling, Behavioral Counseling
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Miami
Pulmonary Hypertension
Dose Determination Safety and Activity Study of Inhaled NX1011 to Treat Pulmonary Arterial Hypertension
The purpose of this study is to determine the safety and maximum tolerated dose of inhaled NX1011 for the treatment of pulmonary arterial hypertension (PAH).
- Trial name
- NCT00323024
- Testing
- NX1011
- Where
- 6 sites in United States
- Volunteers
- 72 people
- Sponsor
- NITROX, LLC
COPD Exacerbation
Effects of Physical Activity Counseling After an Exacerbation in COPD
Severe exacerbations are prevalent in a subgroup of patients with COPD and generally warrant a hospitalization. During the hospitalization, patients are extremely physically inactive with only a limited recovery one month after…
- Trial name
- NCT02223962
- Testing
- Physical activity
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- KU Leuven
Chronic Obstructive Pulmonary Disease
The Effect of Reflective Breathing Therapy Compared With Conventional Breathing Therapy in Patients With Chronic Obstructive Pulmonary Disease (COPD) III-IV
The purpose of this study is to determine whether different types of breathing therapies in patients with COPD III-IV decrease dyspnea and increase activity.
- Trial name
- NCT01478646
- Testing
- conventional breathing therapy, reflectory breathing therapy
- Where
- Germany
- Volunteers
- 24 people
- Sponsor
- Schön Klinik Berchtesgadener Land
Chronic Obstructive Airway Disease
Safety and Efficacy of Inhaled Sedation in Management of Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Brief Summary (Plain Language) This study tests whether using a device called AnaConDa® to give a mild gas medicine (isoflurane) helps people with severe flare-ups of chronic obstructive pulmonary disease (COPD) breathe more…
- Trial name
- NCT07191470
- Testing
- The Anaesthetic Conserving Device (AnaConDa)
- Where
- India
- Volunteers
- 10 people
- Sponsor
- Pandit Bhagwat Dayal Sharma, PGIMS, Rohtak
COPD, COPD Exacerbation
Healthy At Home Pilot
The objective is to conduct a pilot-feasibility trial of the "Healthy at Home" program, a multimodal intervention aimed at preventing acute care needs among COPD patients.
- Conditions
- COPD, COPD Exacerbation, Emphysema or COPD
- Trial name
- NCT06000696
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Massachusetts, Worcester
COPD
Cycled Testosterone Administration During Pulmonary Rehabilitation in Early Stage COPD
Chronic obstructive pulmonary disease (COPD) is characterized by chronic inflammation of the airways and/or damage to the lungs which leads to progressive impairment in airflow and the ability to breathe.
- Trial name
- NCT03674320
- Testing
- Testosterone Enanthate
- Where
- United States
- Sponsor
- The University of Texas Medical Branch, Galveston
Emphysema, Pulmonary, Emphysema or COPD
An Evaluation of the AeriSeal System for CONVERTing Collateral Ventilation Status in Patients With Severe Emphysema
This is a prospective, open-label, multi-center, single-arm study planned to enroll 200 subjects with heterogeneous emphysema and collateral ventilation (CV) in the target lobe.
- Trial name
- CONVERT_II (NCT06035120)
- Testing
- AeriSeal System
- Where
- 38 sites in United States, Australia and 8 more
- Volunteers
- 200 people
- Sponsor
- Pulmonx Corporation
Heart Failure
Compare the Effects of Single Versus Repeated Intracoronary Application of Autologous Bone Marrow-derived Mononuclear Cells on Mortality in Patients With Chronic Post-infarction Heart Failure
Single or repeated application of autologous bone marrow-derived stem cells to treat chronic post-infarction heart failure
- Trial name
- REPEAT (NCT01693042)
- Testing
- intracoronary infusion of autologous bone marrow-derived cells
- Where
- 6 sites in Germany
- Volunteers
- 81 people
- Sponsor
- Johann Wolfgang Goethe University Hospital
Asthma in Children, Protracted Bacterial Bronchitis
Biomarkers and Respiratory Omics as New CHildren Opportunities - Study of Clinical Outcomes and Predictivity Evaluation
The goal of this observational study is to improve the identification of biomarkers that predict disease progression and to assess the effectiveness of current therapies in children with asthma and protracted bacterial…
- Conditions
- Asthma in Children, Protracted Bacterial Bronchitis, Chronic Cough
- Trial name
- BRONCHOSCOPE (NCT07232550)
- Testing
- fiberoptic bronchoscopy, blood sample collection, Respiratory functional tests
- Where
- Poland
- Volunteers
- 160 people
- Sponsor
- Medical University of Warsaw
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