Clinical trials: copd or chronic obstructive
Chronic Obstructive Pulmonary Disease
Effects of Tiotropium on Walking Capacity in Patients With COPD
This study was designed to test the following hypothesis: A) The acute and long-term (3 weeks) bronchodilator-induced changes in exercise tolerance and in the physiological response during the endurance shuttle walk will be…
- Trial name
- NCT01307189
- Testing
- Tiotropium
- Where
- Canada
- Volunteers
- 33 people
- Sponsor
- Laval University
Chronic Obstructive Pulmonary Disease, COPD Exacerbation
Testing a Prediction Algorithm Into a Running Telehealth System for Patients With COPD
This trial will test a COPD prediction algorithm into a telehealth system from the previous Danish large-scale trial, TeleCare North (NCT01984840).
- Conditions
- Chronic Obstructive Pulmonary Disease, COPD Exacerbation, COPD Exacerbation Acute, COPD
- Trial name
- NCT05218525
- Testing
- Algorithm
- Where
- Denmark
- Volunteers
- 138 people
- Sponsor
- Aalborg University
Chronic Graft Versus Host Disease
Positron Emission Tomography - Computed Tomography (PET-CT) Scanning in Chronic Graft Versus Host Disease (cGvHD)
Graft versus Host Disease (GvHD), in both its acute and chronic forms, is the major intrinsic complication of allogeneic hematopoeitic stem cell transplant (allo-HSCT).
- Trial name
- NCT01964625
- Testing
- PET-CT Scan
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Rochester
Severe COPD
Advance Care Planning Individualised Approach and Research Projec
The study will investigate the effect of a palliative approach in the out-patient management of patients with COPD.
- Trial name
- AIR (NCT03915743)
- Testing
- palliative care
- Where
- Denmark
- Volunteers
- 10 people
- Sponsor
- Herlev and Gentofte Hospital
COPD (Chronic Obstructive Pulmonary Disease)
Effect of an App-based Intervention on Air Pollution in COPD Patients
This study will test whether a combination of health education, a mobile app, and a smart band can help people with chronic obstructive pulmonary disease (COPD) improve their quality of life and reduce flare-ups.
- Trial name
- NCT07074093
- Testing
- app+smartband+education
- Where
- Spain
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Fundacion para la Investigacion y Formacion en Ciencias de la Salud
Lung Diseases
Analysis of Anti-inflammatory and Antioxidant Pathways in Lung Diseases by Haem Oxygenase-1 (HO-1) in Induced Sputum and Carbon Monoxide (CO) in Exhaled Air
This work will focus on the anti-inflammatory and antioxidant pathways in lung diseases by measuring HO-1 in induced sputum and CO in exhaled air in cases of four respiratory diseases, asthma, chronic obstructive pulmonary…
- Trial name
- NCT01140685
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Cough
Therapeutic Confirmatory Clinical Trial to Evaluate the Safety and Efficacy of AG1321001 in Chronic Cougher
This study is for therapeutic confirmation of AG1321001 to evaluate the safety and efficacy as an anti-tussive agent in cough patients.
- Trial name
- NCT00380315
- Testing
- AG1321001(drug)
- Where
- South Korea
- Volunteers
- 396 people
- Sponsor
- Ahn-Gook Pharmaceuticals Co.,Ltd
Lung Diseases, Lung Diseases, Obstructive
Nocturnal Oxygen Therapy
To compare the efficacy of long-term use of nocturnal oxygen therapy (12 hours) with that of continuous, low-flow oxygen therapy (24 hours) in patients with chronic hypoxic lung disease.
- Conditions
- Lung Diseases, Lung Diseases, Obstructive, Chronic Obstructive Pulmonary Disease
- Trial name
- NCT00000564
- Testing
- oxygen inhalation therapy
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Pulmonary Disease, Chronic Obstructive
Measure of the Long Term Influence of SPIRIVA® in Acute Respiratory Disorders
The objectives of this study were to evaluate the effect of a one-year treatment with inhaled tiotropium bromide 18 mcg once daily on lung function, incidence and severity of exacerbations in patients with chronic obstructive…
- Trial name
- NCT00274014
- Testing
- Tiotropium
- Where
- 55 sites in France
- Volunteers
- 1,000 people
- Sponsor
- Boehringer Ingelheim
Pulmonary Disease, Chronic Obstructive
A Randomized Comparative Effectiveness Research Trial of Three Treatments for COPD Patients
The aim of this study is to compare the effectiveness and economic evaluation of three treatments for Chronic Obstructive Pulmonary Disease (COPD) patients: one, conventional medicine based on 2011 Global Initiative for Chronic…
- Trial name
- NCT01836016
- Testing
- Salbutamol (Ventolin®), Formoterol (Oxis Turbuhaler®), Salmeterol / fluticasone (Seretide®)
- Where
- China
- Volunteers
- 360 people
- Sponsor
- Henan University of Traditional Chinese Medicine
Chronic Obstructive Pulmonary Disease
Nitrate Supplementation in Chronic Obstructive Pulmonary Disease (COPD)
Each subject will consume (in a randomized fashion) both the intervention beverage (nitrate solution) and the placebo, separated by a 1 wk washout period.
- Trial name
- NCT02084758
- Testing
- Nitrate supplementation
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- Maastricht University Medical Center
Prostatitis, Chronic Prostatitis With Chronic Pelvic Pain Syndrome
Laparoscopic Prostatectomy for Chronic Prostatitis
Prostatitis is an inflammation of the prostate, an pelvic organ of men. Prostatitis can cause great discomfort which varies but can include pelvic pain, pelvic pressure, a vague sense of discomfort, a feeling of malaise and…
- Trial name
- NCT00775515
- Testing
- laparoscopic prostatectomy
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- The Krongrad Institute
Pulmonary Disease, Chronic Obstructive
Tiotropium Respimat Pharmacokinetic Study in COPD
The purpose of this study is compare the effect of different doses of tiotropium delivered by the HandiHaler and Respimat device on lung function.
- Trial name
- NCT01222533
- Testing
- Tiotropium medium, Tiotropium low, Tiotropium high
- Where
- 11 sites in Belgium, Denmark and 3 more
- Volunteers
- 154 people
- Sponsor
- Boehringer Ingelheim
COPD
High-intensity Interval Training in Patients With COPD: a Fidelity and Tolerability Study
Although high-intensity training (HIIT) is widely used in the rehabilitation of patients with chronic obstructive pulmonary disease (COPD), the optimal duration of intervals in terms of patient tolerability and fidelity is…
- Trial name
- COPDEX-HIIT (NCT05273684)
- Testing
- High intensity interval training
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Chronic Graft Versus Host Disease
Belumosudil and Rituximab for Primary Treatment of Chronic Graft-Versus-Host-Disease
This is an open-label, Phase 2 study designed to evaluate the safety and efficacy of belumosudil and rituximab as primary treatment of cGVHD.
- Trial name
- NCT06046248
- Testing
- Belumosudil, Rituximab
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Northside Hospital, Inc.
Chronic Respiratory Disease, COPD
Chronic Respiratory Disease Burden in Bangladesh
Chronic Respiratory Disease (CRD), particularly asthma and chronic obstructive pulmonary disorders (COPD) are leading causes of mortality and reduced quality of life due to its wide-reported association with other…
- Trial name
- NCT04851808
- Where
- Bangladesh
- Volunteers
- 981 people, healthy volunteers welcome
- Sponsor
- Child Health Research Foundation, Bangladesh
IPF, Sarcoidosis
Nasal, Tracheal and Bronchial Mucosal Lining Fluid(MLF) Sampling From Patients With Respiratory Diseases
Nasal, tracheal and bronchial sampling of MLF in patients with idiopathic pulmonary fibrosis(IPF), sarcoidosis, tuberculosis(TB), asthma and COPD. Similar sampling from healthy controls for comparative data.
- Conditions
- IPF, Sarcoidosis, Tuberculosis, Asthma
- Trial name
- RESPI-SAM (NCT02807025)
- Where
- United Kingdom
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Imperial College Healthcare NHS Trust
Pulmonary Disease, Chronic Obstructive, Lung Diseases, Obstructive
Is the Short Physical Performance Battery a Useful Outcome Measure in Chronic Obstructive Pulmonary Disease
Patients with Chronic Obstructive Lung Disease (COPD) often develop muscle problems, particularly in their legs which makes them more limited in what they can do.
- Conditions
- Pulmonary Disease, Chronic Obstructive, Lung Diseases, Obstructive, Pulmonary Emphysema, Bronchitis, Chronic
- Trial name
- NCT01515709
- Where
- United Kingdom
- Volunteers
- 445 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Asthma,, Chronic Obstructive Pulmonary Disease
Observational Study to Evaluate the Correctness of the Use of Inhaler Device in Patients With Asthma or Chronic Obstruct
The correct use of inhalation devices is an inclusion criterion for all studies comparing inhaled treatments. In real life, however, patients may make many errors with their usual inhalation device, which may negate the benefits…
- Trial name
- NCT01426893
- Where
- 5 sites in Serbia
- Volunteers
- 310 people
- Sponsor
- AstraZeneca
Patient Engagement
Effect of Thyme Oil on Respiratory Symptoms and Hemodynamic Parameters in COPD Patients
Chronic Obstructive Pulmonary Disease (COPD) is a high-prevalence, preventable and treatable disease characterized by abnormal respiratory symptoms and airway obstruction, often resulting from exposure to hazardous substances due…
- Trial name
- NCT06156449
- Testing
- Thyme oil
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Inonu University
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