Clinical trials: copd or chronic obstructive
Pulmonary Disease, Chronic Obstructive
A Study to Evaluate the Effect of Itraconazole on the Concentration of GSK3923868 in the Blood in Healthy Participants
The purpose of this study is to evaluate how itraconazole affects the blood concentration of GSK3923868 in healthy adults.
- Trial name
- NCT06597500
- Testing
- GSK3923868, Itraconazole
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Pulmonary Disease, Chronic Obstructive
Inhaled Bronchodilator Association and Quality of Life in Patients With Chronic Obstructive Pulmonary Disease
A pharmaco-epidemiological, observational study that aimed at assessing in a prospective manner the evolution of Quality of Life (QOL) in chronic obstructive pulmonary disease (COPD) patients treated with inhaled bronchodilators
- Trial name
- NCT02176564
- Testing
- inhaled bronchodilator
- Volunteers
- 2,639 people
- Sponsor
- Boehringer Ingelheim
Pulmonary Disease, Chronic Obstructive, Respiratory Tract Infections
Viral Infections in Chronic Obstructive Pulmonary Disease (COPD) Exacerbations
The objectives of the study are to determine the prevalence of respiratory virus infections in COPD patients, during and outside acute exacerbation to explore the impact of these viral infections on the outcome of these patients…
- Conditions
- Pulmonary Disease, Chronic Obstructive, Respiratory Tract Infections, Virus Diseases, Lung Diseases, Obstructive
- Trial name
- VICE (NCT00448604)
- Where
- Switzerland
- Volunteers
- 86 people
- Sponsor
- University Hospital, Geneva
Chronic Obstructive Pulmonary Disease (COPD)
Comprehensive Disease Management Program in Chronic Obstructive Pulmonary Disease (COPD) Patients in the Community
The purpose of this study is to determine whether comprehensive disease management program combined with best care recommended in clinical guidelines, is more effective than best care alone in patients with advanced chronic…
- Trial name
- COPD_CDM (NCT00982384)
- Testing
- Disease management, Best care
- Where
- 2 sites in Israel
- Volunteers
- 1,202 people
- Sponsor
- Sheba Medical Center
COPD, Emphysema
Mechanistic Effects of Health Coaching to Reduce Chronic Obstructive Pulmonary Disease (COPD) Hospitalizations
The researchers are trying to explore the benefit of Health Coaching on patients with severe symptoms of COPD.
- Trial name
- NCT03837847
- Testing
- Health Coaching Calls, Control
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Mayo Clinic
COPD Exacerbation, COPD (Chronic Obstructive Pulmonary Disease) With Acute Lower Respiratory Infection
Study on Home Obstructive Respiratory Exacerbations
Strados Labs has developed the Strados™ Respiratory Care Platform, including the RESP™ Biosensor System, which encompasses a clinically validated wearable, non-invasive, Bluetooth-enabled device capable of remotely collecting…
- Conditions
- COPD Exacerbation, COPD (Chronic Obstructive Pulmonary Disease) With Acute Lower Respiratory Infection, COPD Exacerbation Acute, COPD
- Trial name
- SHORE (NCT06544928)
- Testing
- RESP™ Biosensor
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Strados Labs, Inc.
Asthma, Breast Cancer
Collaborative Self-Management Support in Chronic Conditions - Qualitative Study
The management of chronic conditions is a challenge for health systems worldwide, particularly in the context of an aging population, and requires urgent improvement of health services.
- Conditions
- Asthma, Breast Cancer, Stroke
- Trial name
- CoSMaS-ql (NCT03262428)
- Testing
- Semi-structured interviews
- Where
- France
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Chronic Obstructive Pulmonary Disease (COPD)
Efficacy and Safety of Levalbuterol in Chronic Obstructive Pulmonary Disease (COPD)
To investigate the efficacy and safety of repeated dosing of Levalbuterol over 6 weeks of treatment in COPD.
- Trial name
- NCT00665600
- Testing
- Levalbuterol HCl, Albuterol Sulfate
- Where
- 24 sites in United States, Canada
- Volunteers
- 257 people
- Sponsor
- Sumitomo Pharma America, Inc.
Chronic Obstructive Pulmonary Disease
REported Outcomes in COPD With Trixeo in Real worlD
Chronic obstructive pulmonary disease (COPD) is characterized by persistent respiratory symptoms (including breathlessness, cough, and sputum production), which has a substantial impact on health-related quality of life (HRQoL).
- Trial name
- RECORD (NCT05213611)
- Where
- 31 sites in United Kingdom
- Volunteers
- 150 people
- Sponsor
- AstraZeneca
Chronic Obstructive Pulmonary Disease (COPD), Smoking Cessation
Personalized Smoking Cessation Infographic in COPD
This study assesses the effect of a personalized smoking cessation infographic on physician smoking cessation counseling rates and smoking cessation pharmacotherapy prescription rates.
- Trial name
- NCT04119934
- Testing
- Smoking Cessation Intervention Tool
- Where
- Canada
- Volunteers
- 83 people
- Sponsor
- Unity Health Toronto
COPD Exacerbation Acute
CRP, Procalcitonin and Pro-BNP as Diagnostic and Prognostic Markers in AECOPD
Acute Exacerbations of Chronic Obstructive Pulmonary Disease (AECOPD) are one of the chief causes for admission to Emergency Department. AECOPD is a significant cause for mortality and morbidity worldwide.
- Trial name
- AECOPD (NCT06514599)
- Where
- Turkey (Türkiye)
- Volunteers
- 196 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Pulmonary Disease, Chronic Obstructive, Enterovirus Infections
First-in-human Clinical Trial Evaluating CUR-N399 in Healthy Volunteers.
The purpose of the trial is to evaluate CUR-N399, a PI4KB inhibitor, in a first-in-human trial to evaluate the safety, tolerability and pharmacokinetics profile of single and multiple ascending doses in healthy adults.
- Conditions
- Pulmonary Disease, Chronic Obstructive, Enterovirus Infections, Rhinovirus
- Trial name
- NCT05016687
- Testing
- CUR-N399
- Where
- Sweden
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Curovir AB
Chronic Obstructive Pulmonary Disease
Evaluation of a Portable Oxygen Concentrator During Ambulation for Patients Who Require Supplemental Oxygen (POC-LEAN)
Prospective randomized study with a cross-over design. Mobi™ is a relatively new POC in the market and thus it is valuable to collect data from COPD patients using supplemental oxygen, and their use on Mobi™.
- Trial name
- NCT04107493
- Testing
- Portable Oxygen Cylinder, Mobi
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- ResMed
Chronic Obstructive Pulmonary Disease Severe, Muscle Weakness
Additional Manual Therapy Over Inspiratory Muscle Training in COPD
The benefits of inspiratory muscle training(IMT) in patients with chronic obstructive pulmonary disease(COPD) were reported.But in severe COPD patients, benefit from IMT may be limited.There is need for further research in new…
- Trial name
- NCT04533516
- Testing
- Manual therapy technics, Inspiratory Muscle Training
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istinye University
Chronic Obstructive Pulmonary Disease
The Effect of Respiratory Muscle Strength and Functional Capacity on Posture and Balance
As a result of the study, inspiratory muscle strength, posture and physical performance evaluations of individuals with Chronic Obstructive Pulmonary Disease will be made, suggestions will be made to help individual postural…
- Trial name
- NCT05005533
- Testing
- Observational
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Abant Izzet Baysal University
Emphysema or COPD
Evaluation of the Free Flow Medical Lung Tensioning Device System for the Treatment of Severe Emphysema
Patients with severe emphysema have limited options for treatment. Current treatments include lung transplant, lung volume reduction surgery or endobronchial lung volume reduction using valves or coils.
- Trial name
- EFFORT (NCT04520152)
- Testing
- FreeFlowMedical Lung Tensioning Device
- Where
- 2 sites in Germany, Netherlands
- Volunteers
- 14 people
- Sponsor
- University Medical Center Groningen
Chronic Obstructive Pulmonary Disease
Screening Evaluation for Studies of Chronic Obstructive Pulmonary Disease (COPD)
This research is being done to study mechanisms of progression of COPD and to develop treatments for it. The investigators are doing the present study to identify people age 40 and older with mild to moderate COPD who will…
- Trial name
- NCT00889447
- Where
- United States
- Volunteers
- 670 people
- Sponsor
- Johns Hopkins University
Chronic Low-back Pain, Lumbar Facet Joint Syndrome
Ultrasound-guided LMBB by Caudal-cranial Approach: Radiographic Comparison of a New Ultrasound-guided Method
The current standard technique is radiography requiring three uni- or bilateral punctures (transverse-axial plane). The ultrasound technique is also described mainly in this plan but a new "caudal-cranial" ultrasound-guided…
- Trial name
- BLEPAC (NCT05930236)
- Testing
- Lumbar medial branch block, Lidocain, Methylprednisolone
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Erasme University Hospital
COPD Exacerbation
Stratified TreAtment to Reduce Risk in COPD
To evaluate the efficacy of blood-eosinophil directed corticosteroid therapy using near-patient testing, compared to current standard practice during an exacerbation of COPD in a multi-centre randomised placebo controlled trial.
- Trial name
- STARR2 (NCT04458636)
- Testing
- Prednisolone
- Where
- United Kingdom
- Volunteers
- 203 people
- Sponsor
- University of Oxford
Chronic Obstructive Pulmonary Disease, COPD
Effect of QVA149 (Indacaterol Maleate/Glycopyrronium Bromide) on Cardiac Function in COPD Patients
This mechanistic study is a single-center, randomized, double-blind, placebo-controlled, cross-over study to evaluate the effect of dual bronchodilation with QVA149 on cardiac and lung function parameters in hyperinflated COPD…
- Trial name
- CLAIM (NCT02442206)
- Testing
- QVA149
- Where
- Germany
- Volunteers
- 62 people
- Sponsor
- Novartis Pharmaceuticals
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