Clinical trials: copd or chronic obstructive
Chronic Obstructive Pulmonary Disease (COPD), Whole Body Vibration
Acute Effect of Different Frequency of Whole Body Vibration (WBV) on Healthy and Chronic Obstructive Pulmonary Disease (COPD)
Chronic obstructive pulmonary disease (COPD) is an irreversible disorder characterized by persistent airflow limitation and increased lung compliance.
- Trial name
- NCT07509606
- Testing
- Whole body vibration
- Where
- Taiwan
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- National Cheng Kung University
Lung Disease
Use of Autologous, Adult Adipose-Derived Stem/Stromal Cells In Chronic Lung Disorders
Chronic Obstructive Pulmonary Disease (COPD) is a lung-related disorder that is characterized by long-term, often progressive state of poor airflow.
- Trial name
- ADcSVF-COPD (NCT02946658)
- Testing
- lipoaspiration, ADcSVF, Normal Saline IV
- Where
- 2 sites in United States, Honduras
- Volunteers
- 100 people
- Sponsor
- Healeon Medical Inc
COPD Exacerbation, Enoximone
The Effects of Enoximone in Acute Exacerbation COPD
Introduction: The pharmacodynamic properties of enoximone could be beneficial for patients with an Acute Exacerbation COPD (AE-COPD).
- Conditions
- COPD Exacerbation, Enoximone, Phosphodiesterase Inhibitor
- Trial name
- NCT04420455
- Testing
- Enoximone
- Where
- Netherlands
- Volunteers
- 3 people
- Sponsor
- Rijnstate Hospital
COPD Exacerbation, Pneumonia
Comparison of Multiple Oxygenation Targets With Different Oximeters in Chronic Obstructive Pulmonary Disease (COPD) and Non-COPD Patients- Impact on Oxygen Flows
The oximeter is an instrument for monitoring patients receiving oxygen therapy. It displays pulse oxygen saturation (SpO2), which is a reflection of arterial oxygen saturation (SaO2).
- Conditions
- COPD Exacerbation, Pneumonia, Hypoxemia, Respiratory Disease
- Trial name
- NCT05819164
- Testing
- Masimo oximeter, Nellcor oximeter, Nonin oximeter
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Laval University
Patient Engagement
Effect of Thyme Oil on Respiratory Symptoms and Hemodynamic Parameters in COPD Patients
Chronic Obstructive Pulmonary Disease (COPD) is a high-prevalence, preventable and treatable disease characterized by abnormal respiratory symptoms and airway obstruction, often resulting from exposure to hazardous substances due…
- Trial name
- NCT06156449
- Testing
- Thyme oil
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Inonu University
COPD Exacerbation
Using a Closed-loop System for Oxygen Delivery (FreeO2) to Optimize Oxygentherapy in Patients With COPD Exacerbation
Aim: The purpose of this study is to evaluate the use feasibility of FreeO2 so as to deliver automatically oxygen and to enable a remote medical monitoring with a homogeneous patient population hospitalize for Chronic obstructive…
- Trial name
- NCT01393015
- Testing
- Automated settings on the oxygen delivery device, Manual settings with FreeO2 system in collection mode
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Quebec
COPD
COPD and Socially Vulnerable Individuals
The trial investigates and describes the prevalence of COPD in patients who are in the social nurses' target group and investigates the effect of opportunistic screening for COPD in these vulnerable patients.
- Trial name
- NCT04754308
- Testing
- Spirometry
- Where
- 10 sites in Denmark
- Volunteers
- 513 people
- Sponsor
- Hvidovre University Hospital
COPD, Chronic Obstructive Pulmonary Disease
Effect of BDP/Formoterol/G on Cough Efficacy in Moderate to Severe COPD Patients (EFFICACE)
This prospective, single centre, 8 weeks, open-label study is designed to evaluate in real-life the effect of triple Beclometasone/Formoterol/Glycopyrronium (BDP/F/G) therapy on cough efficacy, assessed by cough peak flow (CPF)…
- Trial name
- EFFICACE (NCT05114434)
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Parma
Chronic Obstructive Pulmonary Disease
Nitrate Supplementation in Chronic Obstructive Pulmonary Disease (COPD)
Each subject will consume (in a randomized fashion) both the intervention beverage (nitrate solution) and the placebo, separated by a 1 wk washout period.
- Trial name
- NCT02084758
- Testing
- Nitrate supplementation
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- Maastricht University Medical Center
Respiratory Failure, Congestive Heart Failure
Effect of High-flow Nasal Oxygen on Extubation Outcome
The purpose of this study is to determine whether high flow nasal cannula is effective in lowering the reintubation rate after extubation for high risk patients in medical intensive care unit
- Conditions
- Respiratory Failure, Congestive Heart Failure, COPD
- Trial name
- NCT02290548
- Testing
- high flow nasal cannula
- Where
- Taiwan
- Volunteers
- 400 people
- Sponsor
- Mackay Memorial Hospital
Chronic Obstructive Pulmonary Disease
Sensitivity of New Exercise Tests in Chronic Obstructive Pulmonary Disease (COPD)
This study was designed to test the following hypothesis: The 3-min constant rate step test and the 3-min constant rate shuttle walk test will be sensitive to detect improvement in exertional dyspnea following acute…
- Trial name
- NCT00807534
- Testing
- ipratropium bromide, constant rate step test, constant rate shuttle walk test
- Where
- 2 sites in Canada
- Volunteers
- 44 people
- Sponsor
- Laval University
Pulmonary Disease, Chronic Obstructive
Berodual® Respimat® vs Metered Dose Inhaler in Patients With Chronic Obstructive Pulmonary Disease
Study to compare the effect of 'natural' as opposed to 'optimal' technique on the percentage of the dose received from the Respimat® inhaler and metered dose inhaler
- Trial name
- NCT02176187
- Testing
- Berodual® Respimat® inhaler, Berodual® metered dose inhaler
- Volunteers
- 3 people
- Sponsor
- Boehringer Ingelheim
Chronic Obstructive Pulmonary Disease
Molecular, Cytological Features and Genetic Susceptibility of COPD Attributable to Different Environmental Exposures
The objective of this study is to investigate molecular, cytological and genetic features of occupational chronic obstructive pulmonary disease (COPD) in conditions of different occupational exposures.
- Trial name
- NCT02220387
- Testing
- exposure to respirable silica dust, exposure to polycyclic aromatic hydrocarbons exhaust
- Where
- Russia
- Volunteers
- 352 people
- Sponsor
- Novosibirsk City Hospital #2
Myeloid Leukemia, Chronic, Chronic Phase
Comparison of Imatinib Versus Dasatinib in Patients With Newly-diagnosed Chronic Phase Chronic Myeloid Leukaemia
Imatinib 400mg daily is the current NICE-approved standard treatment for newly diagnosed Chronic Myeloid Leukaemia (CML). 5 yr follow up of CML patients treated in this way indicates an 89% probability of progression-free…
- Trial name
- SPIRIT2 (NCT01460693)
- Testing
- Imatinib, Dasatinib
- Where
- United Kingdom
- Volunteers
- 814 people
- Sponsor
- Newcastle University
Chronic Obstructive Pulmonary Disease (COPD)
Effect of Supplementary Vitamins on Oxidant Gene Expression in the Lungs of Healthy Smokers
Smoking damages the airway epithelium. The major mechanism by which this is done is by molecules called free radicals. Our body attempts to deal with these damaging molecules in two ways.
- Trial name
- NCT00565214
- Testing
- Group 1, Group 2
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Pulmonary Disease, Chronic Obstructive
Safety, Tolerability and Pharmacokinetics and Effect on Inflammation of Oral BI 1026706 in Patients With COPD
The main objective of the current trial is to investigate safety, tolerability, pharmacokinetics and effect on inflammation of oral BI 1026706 administered twice daily for 4 weeks in patients with COPD.
- Trial name
- NCT02642614
- Testing
- BI 1026706
- Where
- 10 sites in Denmark, Germany and 2 more
- Volunteers
- 120 people
- Sponsor
- Boehringer Ingelheim
Chronic Obstructive Pulmonary Disease, Cardiovascular Disease
Selenium Supplementation in Chronic Obstructive Pulmonary Disease (COPD) Patients
Does an oral selenium supplement increase blood levels of antioxidants in patients with established, smoking-related lung disease? Members of our study group recently discovered that elevated levels of the anti-oxidant GPx-1 may…
- Trial name
- NCT00186706
- Testing
- Selenium
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- St. Joseph's Health Care London
Chronic Obstructive Pulmonary Disease (COPD)
This After Market Study is Seeing if Dupilumab Plus Usual Standard of Care (SOC) is Better Than Usual Care Alone for Adult Participants After a Severe Chronic Obstructive Pulmonary Disease (COPD) Flare-Up Requiring Hospitalization
This study is researching a drug called dupilumab, referred to as "study drug". The study is focused on people diagnosed with COPD to determine if the study drug, in addition to standard of care treatment for COPD, might reduce…
- Trial name
- MISSION (NCT07587658)
- Testing
- dupilumab
- Where
- United States
- Volunteers
- 754 people
- Sponsor
- Regeneron Pharmaceuticals
COPD Exacerbation, Noninvasive Ventilation
Structured Discharge and Follow-up Protocol for COPD Patients Receiving LTOT and NIV
Readmission to hospital is one of the most important problems in chronic obstructive pulmonary disease (COPD) patients who developed chronic respiratory failure.
- Conditions
- COPD Exacerbation, Noninvasive Ventilation, Long Term Oxygen Therapy, Chronic Respiratory Failure
- Trial name
- NCT03499470
- Testing
- Protocol for structured discharge and follow-up
- Where
- 10 sites in Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Dokuz Eylul University
Chronic Obstructive Pulmonary Disease, Asthma
Effectiveness and Implementation of the Assessment of Burden of Chronic Conditions (ABCC)-Tool
This study is designed to evaluate the effectiveness and implementation of the Assessment of Burden of Chronic Conditions (ABCC)-tool for patients with COPD, asthma, diabetes mellitus type 2 or heart failure (and any combination…
- Conditions
- Chronic Obstructive Pulmonary Disease, Asthma, Diabetes Mellitus, Type 2, Heart Failure
- Trial name
- NCT04127383
- Testing
- Assessment of Burden of Chronic Conditions (ABCC)-tool
- Where
- Netherlands
- Volunteers
- 237 people
- Sponsor
- Maastricht University
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