Clinical trials: copd or chronic obstructive
COPD
Home Non-Invasive Ventilation Targeting Expiratory Flow Limitation in Severe Hypercapnic COPD.
In this 2-phase pilot study, the BiPAP A40 EFL will be evaluated in patients with severe COPD requiring home non-invasive ventilatory support with respect to patient-related and physiologic outcomes.
- Trial name
- NCT05109754
- Testing
- BiPAP EFL
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
COPD
Innovative Pulmonary Rehabilitation Telehealth Program for Improving COPD Patient Outcomes
Researchers want to learn more about telehealth pulmonary rehabilitation programs that help people with Chronic obstructive pulmonary disease (COPD) improve physical activity and quality of life.
- Trial name
- NCT03489642
- Testing
- Telehealth Program
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Kansas Medical Center
Anemia, Iron-Deficiency, Kidney Failure, Chronic
Effect of Ferrlecit® Versus Oral Iron on Iron Deficient Chronic Kidney Disease (CKD) Patients Receiving Erythropoietic Agents
This study compares the effect of Ferrlecit® (a form of intravenous iron) to ferrous sulfate (a form of oral iron) in treating anemia and iron deficiency in chronic kidney disease patients who are receiving erythropoietic agents…
- Trial name
- NCT00224042
- Testing
- Sodium Ferric Gluconate complex in sucrose, Ferrous sulfate tablets
- Where
- 24 sites in United States, Puerto Rico
- Volunteers
- 52 people
- Sponsor
- Watson Pharmaceuticals
Chronic Obstructive Pulmonary Disease (COPD)
Effects of Different Modes of Respiratory MuscleTraining on Respiratory Mechanics and NRD in Patient With Stable COPD.
Chronic Obstructive Pulmonary Disease (COPD) is a chronic respiratory disease characterized by persistent airflow limitation. The patients are suffering dyspnea year by year, resulting in the decreased exercise tolerance and…
- Trial name
- NCT03500042
- Testing
- inspiratory pressure threshold device
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Zhujiang Hospital
SAA Level and SAA/Lipoxin A4 Ratio
Evaluation of Biomarkers of COPD Exacerbation
Serum amlyoid A (SAA) was shown to act as biomarker for exacerbation of chronic obstructive pulmonary disease (AE-COPD). It seems that SAA triggers chronic inflammation by binding to ALX/PFR2 receptor.
- Trial name
- NCT03609541
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- Heidelberg University
Moderate to Severe COPD Receiving Home Exercise Training
Mobile-phone-based Home Exercise in Chronic Obstructive Pulmonary Disease
Background: Moderate-intensity exercise training improves skeletal muscle aerobic capacity and increased oxidative enzyme activity, as well as exercise tolerance in Chronic Obstructive Pulmonary Disease (COPD) patients.
- Trial name
- NCT01631019
- Testing
- Mobile-phone-based Home Exercise Training Program, Home Exercise Training Program
- Where
- Taiwan
- Volunteers
- 26 people
- Sponsor
- Chang Gung Memorial Hospital
Chronic Coronary Syndrome, Coronary Disease
SECURE Trial: Stress Echocardiography With Carotid Ultrasound vs Routine CT Coronary Angiography in Chronic Coronary Syndrome for Endpoints
Diseases of the heart and circulation are known as cardiovascular diseases, and they cause over 160,000 deaths each year. Coronary heart disease (CHD) is the most common cardiovascular disease.
- Conditions
- Chronic Coronary Syndrome, Coronary Disease, Coronary Artery Disease
- Trial name
- SECURE (NCT06185530)
- Testing
- Detection of obstructive coronary disease
- Where
- United Kingdom
- Volunteers
- 2,000 people
- Sponsor
- London North West Healthcare NHS Trust
COPD
Dose-Ranging Study in Patients With Chronic Obstructive Pulmonary Disease (COPD)
The trial is designed to identify an appropriate dose of QAB149 for delivery via a multiple dose inhaler for use in the COPD Phase III program.
- Trial name
- NCT00098228
- Testing
- QAB149
- Where
- 54 sites in United States
- Volunteers
- 686 people
- Sponsor
- Novartis Pharmaceuticals
Chronic Obstructive Pulmonary Disease
A Pilot Trial of a Smartphone-based Self-management Support Program for COPD Patients
COPD patients often experience multiple symptoms (e.g. dyspnea, cough, and deteriorating quality of life) and have imposed a substantial economic and social burden on health care.
- Trial name
- NCT05192083
- Testing
- Self-management and Support
- Where
- Hong Kong
- Volunteers
- 14 people
- Sponsor
- The University of Hong Kong
Chronic Obstructive Pulmonary Disease
Evidence-based Analysis of Low-dose CT in Management of COPD
Background: Chronic obstructive pulmonary disease (COPD) is the fourth leading cause of chronic morbidity and mortality worldwide.
- Trial name
- NCT02599883
- Testing
- Low-Dose Computed Tomography
- Volunteers
- 195 people
- Sponsor
- Azienda Ospedaliero-Universitaria di Parma
Pulmonary Disease, Chronic Obstructive
Safety and Efficacy of BI 1744 CL in Patients With Chronic Obstructive Pulmonary Disease I
The primary objective of this study is to assess the long-term efficacy and safety of once daily treatment of BI 1744 CL inhalation solution (5 and 10 mcg) delivered via the Respimat® inhaler, in patients with COPD.
- Trial name
- NCT00793624
- Testing
- Olodaterol (BI 1744), Formoterol
- Where
- 93 sites in Argentina, Brazil and 18 more
- Volunteers
- 906 people
- Sponsor
- Boehringer Ingelheim
COPD
A Novel Incremental Step Test as an Alternative for the Assessment of Exercise Capacity in Patients With COPD
According to the official guidelines of pulmonary rehabilitation, a structured home-based approach is recommended to answer to the inadequate number of pulmonary rehabilitation services due to the chronic obstructive pulmonary…
- Trial name
- NCT04715659
- Testing
- Performance of step test (number of steps) for the assessment of exercise capacity
- Where
- Portugal
- Volunteers
- 50 people
- Sponsor
- Polytechnic Institute of Porto
Chronic Obstructive Pulmonary Disease
Impact of a Hospital Physical Therapy Program on Chronic Obstructive Pulmonary Disease (COPD) Patients
The Chronic Obstructive Pulmonary Disease is a leading global cause of morbidity and mortality, so it's important to find actions that could improve quality of life and decrease the mortality.
- Trial name
- NCT01295359
- Testing
- Ground Walking Program
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Universidade Federal de Sao Carlos
Chronic Obstructive Pulmonary Disease Moderate
Beetroot Juice - Effects on Performance in Chronic Obstructive Pulmonary Disease Patients
The purpose is to evaluate exercise performance in patients with Chronic Obstructive Pulmonary Disease (COPD) after supplementing with higher doses of dietary NO3-, compared to previous studies, as beetroot juice for seven days.
- Trial name
- COPD (NCT03020862)
- Testing
- Dietary beetroot juice
- Where
- Denmark
- Volunteers
- 15 people
- Sponsor
- University of Aarhus
COPD
Imaging Regional Lung Defect Severity
The purpose of this study is to develop and evaluate the usefulness of magnetic resonance imaging (MRI) using inert perfluorinated gases mixed with oxygen for regional assessment of pulmonary function.
- Trial name
- DIAL1001004 (NCT01640288)
- Testing
- Perfluorinated Gas/Oxygen Mixture, High Resolution CT of the Chest
- Where
- United States
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- Hal C Charles
Chronic Low Back Pain
Identification of Prognostic Indicators for Rehabilitation in Chronic Nonspecific Low Back Pain Patients
There is a consensus that exercise therapy should be used as a therapy approach in CLBP but little consensus has been reached about the preferential type of therapy.
- Trial name
- NCT02063503
- Testing
- physiotherapy
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- Universiteit Antwerpen
COPD (Chronic Obstructive Pulmonary Disease)
Inhaled Treprostinil for Dyspnea and Exercise Intolerance in Mild COPD
The goal of this clinical trial is to evaluate the impact of inhaled Treprostinil on breathlessness and low exercise capacity in patients living with mild chronic obstructive pulmonary disease.
- Trial name
- NCT06969573
- Testing
- Treprostinil Inhalation Solution 36 mcg, Treprostinil Inhalation Solution 78 mcg
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Alberta
Asthma, Chronic Obstructive Pulmonary Disease
Clinic Versus Home Spirometry
The study aims to assess the differences between spirometry performed with the NuvoAir Air Next spirometer in the clinic setting with both direct and virtual supervision via a video call, and in the home setting with virtual…
- Trial name
- COMPAIR (NCT05219773)
- Testing
- NuvoAir Air Next spirometer
- Where
- 3 sites in United Kingdom
- Volunteers
- 68 people
- Sponsor
- University of Nottingham
COPD, Emphysema
Right Ventricular Diastolic Dysfunction
Heart-lung interactions remain misunderstood whereas pulmonary and cardiac pathologies are very commonly associated. Emphysema by increasing intrathoracic pressure appears to affect cardiac function.
- Conditions
- COPD, Emphysema, Right Heart Dysfunction
- Trial name
- RVDD (NCT04467242)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Montpellier
Tinnitus
The Effect of Gabapentin on the Sensation and Impact of Tinnitus
This study evaluated the effectiveness of gabapentin in treating tinnitus in two populations: Tinnitus with associated acoustic trauma and tinnitus without associated acoustic trauma.
- Trial name
- NCT00257270
- Testing
- gabapentin
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tinnitus Research Consortium
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