Clinical trials: no Conditions
No Disease State or Condition
Pain Study to Assess Local Anesthetic Efficacy and Safety of CTY-5339 on Gingival Mucosal Tissue in Normal Volunteers
The purpose of this study is to determine if the topical application to gingival tissue of the combination of benzocaine and tetracaine has a longer duration of local anesthetic activity than benzocaine alone.
- Trial name
- NCT03233737
- Testing
- One spray CTY-5339-A, One spray CTY-5339-CB, One spray CTY-5339-P
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Cetylite Industries
No Condition
Performance Thresholds Evaluation by Wet Injection Quantification and Magnetic Resonance Imaging (MRI) of Subcutaneous and Intramuscular Injections (0,65ml) of Several Configurations of Needle-free Devices (ZENEO®)
The aim of this study is to evaluate the performance of the ZENEO needle free device in subcutaneous functioning limits (low performance limit and high performance limit) and for intramuscular injections.
- Trial name
- NCT03044301
- Testing
- Intramuscular ZENEO® injection, Subcutaneous high ZENEO® injection, Subcutaneous low ZENEO® injection
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Crossject
No Specific Medical Conditions or Disease States
Pilot Evaluation of an Continuous Contactless Vitals Parameter Monitoring System Dozee VS
The Dozee VS device developed by Turtle Shell Technologies Pvt. Ltd., is a contactless continuous vital parameters monitoring system.
- Trial name
- NCT05380102
- Testing
- Telemetry monitoring, Continuous monitoring through Earlysense, Continuous monitoring through Dozee VS
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Turtle Shell Technologies Pvt. Ltd.
Healthy
Bioequivalence Study of Fosinopril 40mg Tablets Under Fed Conditions
The objective of this study is to compare the relative bioavailability of fosinopril sodium 40 mg tablets (Ranbaxy Laboratories Limited, Lot No.
- Trial name
- NCT00776672
- Testing
- Fosinopril 40mg Tablets
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Ranbaxy Laboratories Limited
Osteoarthritis, Knee, Pain
A Phase 2 Clinical Trial Examining the Effects on Osteoarthritic Knee Pain of CGS-200-1, CGS-200-5 and Vehicle Control
This is a multi-center, randomized, double-blind clinical trial to examine the comparative effects on OAKP of CGS-200-1 (1% Capsaicin content) (N=40), CGS-200-5 (5% Capsaicin content) (N=40), and CGS-200 Vehicle (no Capsaicin)…
- Trial name
- NCT03528369
- Testing
- CGS-200-1, CGS-200-5, CGS-200 Vehicle
- Where
- 6 sites in United States
- Volunteers
- 122 people
- Sponsor
- Propella Therapeutics
Peripheral Arterial Disease, Critical Limb Ischemia
ACPs in Severe PAD/CLI by Direct Intramuscular Injection
Study title: A Study of Blood-Borne Autologous Angiogenic Cell Precursors Therapy in Patients with Critical Limb Ischemia ( ACPs-CLI ) Principle Investigator: Assoc.Prof. Pramook Mutirangura,M.D.
- Trial name
- NCT00523731
- Testing
- Angiogenic Cell Precursors (ACPs) or Vescell TM
- Where
- Israel
- Volunteers
- 6 people
- Sponsor
- TheraVitae Ltd.
Critical Limb Ischemia
An Efficacy and Safety Study of Ixmyelocel-T in Patients With Critical Limb Ischemia (CLI)
This study is designed to evaluate the efficacy and safety of ixmyelocel-T, a patient-specific expanded multicellular therapy, for the treatment of patients with critical limb ischemia (CLI).
- Trial name
- REVIVE (NCT01483898)
- Testing
- Ixmyelocel-T
- Where
- 86 sites in United States
- Volunteers
- 41 people
- Sponsor
- Vericel Corporation
No Disease or Condition is Being Studied, Evaluating a Brief Intervention
Evaluation of Virtual Reality in Hazmat Training
Type of study: Two-group comparison. Main question it aims to answer: Does the use of virtual reality emergency scenarios provide a practical and effective tool to supplement traditional instructor-led training for first…
- Conditions
- No Disease or Condition is Being Studied, Evaluating a Brief Intervention, Does Virtual Reality Aid in Hazmat Training
- Trial name
- NCT06113406
- Testing
- Classroom Training, Virtual Reality Training
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- MetaMedia Training International, Inc.
Metastatic Pancreatic Adenocarcinoma
Study to Evaluate Efficacy of CO-1.01 as Second Line Therapy for Gemcitabine-Refractory Stage IV Pancreatic Adenocarcinoma
The purpose of this study is to determine whether CO-1.01 is safe and effective for treating metastatic pancreatic cancer that did not respond to gemcitabine.
- Trial name
- NCT01233375
- Testing
- CO-1.01
- Where
- 13 sites in United States
- Volunteers
- 19 people
- Sponsor
- Clovis Oncology, Inc.
Cranial Waveform in Normal Patients as a Result of Cardiac Cycle, Healthy
500 "Normal" Adult Subjects Who Have Experienced no Known Brain Injury Will Participate in Collecting Data That Will Assist With the Optimization of the Diagnostic Capabilities of the Harmony in Detecting Neurologic Abnormalities.
The REFRESH study is designed to collect data related to a signal in the brain that MindRhythm has named the Headpulse. The Headpulse occurs as a natural movement of the brain in conjunction with the beating of the heart.
- Trial name
- REFRESH (NCT05203393)
- Testing
- Harmony Headset
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- MindRhythm, Inc.
No Condition, Healthy Individuals
Microneedle-based ISF Sampling Technique
This clinical investigation aims to evaluate the performance and safety of the PELSA system, a hollow microneedle-based medical device designed for the collection of dermal interstitial fluid (dISF) from human skin.
- Trial name
- MIST (NCT07882225)
- Testing
- PELSA System
- Where
- Germany
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Ascilion AB
Healthy
Pharmacokinetic Interaction Between Ibuprofen and Acetaminophen Oral Suspension
This study was carried out in the Clinical and Analytical Unit of the Pharmacology and Toxicology Department of the Faculty of Medicine of the Autonomous University of Nuevo León, in order to compare the bioavailability (Cmax…
- Trial name
- NCT05428293
- Testing
- A1: Ibuprofen/Acetaminophen Fixed dose combination oral suspension (Laboratorios Silanes S.A. de C.V.), A2: Ibuprofen (Advil®, Pfizer S.A. de C.V.), A3: Acetaminophen (Tylenol®, from Janssen-Cilag, S.A. de C.V.)
- Where
- Mexico
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Laboratorios Silanes S.A. de C.V.
Healthy Volunteers (no Disease Condition Under Study)
A Phase 1, First-in-Human Trial of BLN-481in Healthy Adult Participants
This Phase 1 first-in-human study will evaluate BLN-481 in healthy adults. Participants will receive BLN-481 or placebo. Part 1 evaluates single ascending intravenous (IV) doses (SAD) and optional subcutaneous (SC) doses.
- Trial name
- NCT07903064
- Testing
- BLN-481
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Beeline Medicines Corporation
Alzheimer's Disease, Early Alzheimer's Disease
A Study to Compare Two Different Sleep Tests in Participants With No Symptoms or Early Symptoms of Alzheimer's Disease
The purpose of this study is to compare the results of two different sleep tests in Alzheimer's patients with no symptoms or early symptoms.
- Conditions
- Alzheimer's Disease, Early Alzheimer's Disease, Memory Problems
- Trial name
- NCT07485153
- Testing
- Mobile EEG, Activity Monitor, Sleep Study
- Where
- Singapore
- Volunteers
- 35 people
- Sponsor
- Eli Lilly and Company
No Disease or Condition is Being Studied
Evaluation of the Performance and Safety of VACUSERA® PRP Tubes in the Preparation of Autologous Platelet-Rich Plasma
Study Design After the eligibility assessment during screening and obtaining a written informed consent form, the volunteers' demographic information and medical history will be recorded.
- Trial name
- PRP (NCT07041918)
- Testing
- The study is entirely designed to analyze product performance (analyze only results from whole blood and derived from the PRP tubes), and no interventions will be performed.
- Where
- Turkey (Türkiye)
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- Disera Tıbbi Cihazlar Lojistik Sanayi ve Ticaret A.Ş
Healthy
Bioequivalence Study of Fosinopril 40mg Tablets Under Fasting Conditions
The objective of this study is to compare the relative bioavailability of fosinopril sodium 40 mg tablets (Ranbaxy Laboratories Limited, Lot No. 1238312) with that of Monopril® in healthy adult subjects under fasting conditions.
- Trial name
- NCT00776334
- Testing
- Fosinopril 40mg Tablets
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ranbaxy Laboratories Limited
Chronic Pain, Low Back Pain
Evaluation of Effectiveness and Tolerability of Tapentadol Hydrochloride in Subjects With Severe Chronic Low Back Pain Taking Either WHO Step I or Step II Analgesics or no Regular Analgesics
The main objective of the study is to evaluate the effectiveness, tolerability, and safety of tapentadol hydrochloride prolonged release in subjects suffering from severe chronic low back pain (LBP) who are taking either WHO Step…
- Trial name
- NCT00983385
- Testing
- Tapentadol PR, Observation period
- Where
- 46 sites in Austria, Croatia and 7 more
- Volunteers
- 208 people
- Sponsor
- Grünenthal GmbH
N/A, as no Specific Medical Condition Will be Treated
A Study to Evaluate the Distribution of Botulinum Neurotoxin Type A Administered as Intradermal Injections, Comparing Different Doses, Concentrations, and Delivery Methods
The purpose of this study is to evaluate the distribution of IncobotulinumtoxinA (Xeomin) in healthy subjects at different volumes, concentrations and doses when administered intradermally and subcutaneously using different…
- Trial name
- NCT05585398
- Testing
- IncobotulinumtoxinA
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Merz Pharmaceuticals GmbH
Healthy
Components of Chlorhexidine Gluconate Dressing
The purpose of this study is to determine the contents of a chlorhexidine-containing dressing after use.
- Trial name
- NCT01112020
- Testing
- CHG Catheter Dressing Patch, Biopatch, Tegaderm CHG
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- C. R. Bard
no Condition
Bioequivalence Study of Two Different Formulations of N-acetyl-cysteine (NAC)
Study primary Objective: To evaluate the bioequivalent rate (Cmax) and extent (AUC0-t) of absorption of N-acetyl-cysteine 600 mg uncoated tablets vs.
- Trial name
- NCT02265224
- Testing
- N-acetylcysteine
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Zambon SpA