Clinical trials: no Conditions
Opioid Use, Prescription Drug Abuse and Dependency
No Opioids PrescrIptions On Discharge After Surgery
Opioid analgesics are routinely prescribed for these patients for post-operative pain control. Even a short exposure to opioids in opioid-naïve patients following minor or major surgery has been associated with de novo habitual…
- Conditions
- Opioid Use, Prescription Drug Abuse and Dependency, Surgery, Postoperative Pain
- Trial name
- NOPIOiDS (NCT04469868)
- Testing
- No opioids at discharge
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- Albany Medical College
Pelvic Floor Disorders, Fecal Incontinence
Lateral Episiotomy or Not in Vacuum Assisted Delivery in Non-parous Women
Nulliparous women with a live singleton pregnancy in cephalic presentation past 34 gestational weeks will be randomized to lateral episiotomy or no episiotomy when operative vaginal delivery by vacuum extraction is indicated.
- Conditions
- Pelvic Floor Disorders, Fecal Incontinence, Dystocia, Fetal Hypoxia
- Trial name
- EVA (NCT02643108)
- Testing
- Lateral episiotomy
- Where
- 8 sites in Sweden
- Volunteers
- 717 people
- Sponsor
- Karolinska Institutet
Obesity
Intensive Weight Loss Intervention Versus Usual Care for Adults With Obesity
In this trial, the aim is to assess the clinical benefits and harms, as well as cost-effectiveness of an intensive weight loss (IWL) intervention that includes total dietary replacements, behavioural support and weight-loss…
- Trial name
- LightCARE (NCT06321432)
- Testing
- Intensive weight loss intervention, Usual care
- Where
- 10 sites in Denmark, United Kingdom
- Volunteers
- 480 people
- Sponsor
- Carsten Dirksen
Coronary Artery Disease
Colchicine Protective Effect in Patients Undergoing Percutaneous Coronary Intervention (COLCHICINE-PROTECT)
The goal of this clinical trial is to evaluate the colchicine protective effect in patients undergoing Percutaneous Coronary Intervention (PCI).
- Trial name
- NCT05739929
- Testing
- Colchicine 0.5 MG Oral Tablet
- Where
- Egypt
- Volunteers
- 400 people
- Sponsor
- Helwan University
Cranial Waveform in Normal Patients as a Result of Cardiac Cycle, Healthy
500 "Normal" Adult Subjects Who Have Experienced no Known Brain Injury Will Participate in Collecting Data That Will Assist With the Optimization of the Diagnostic Capabilities of the Harmony in Detecting Neurologic Abnormalities.
The REFRESH study is designed to collect data related to a signal in the brain that MindRhythm has named the Headpulse. The Headpulse occurs as a natural movement of the brain in conjunction with the beating of the heart.
- Trial name
- REFRESH (NCT05203393)
- Testing
- Harmony Headset
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- MindRhythm, Inc.
There Are no Conditions Under Study. Healthy Volunteers
Eccentric Cycling Exercise With Assistive Devices on Mitochondrial Metabolism in T Lymphocyte
Eccentric cycling exercise can be a promising modality fwith lower respiratory demands and higher power output. Assistive devices like neuromuscular electrical stimulation (NMES) and compressive garment (CG) accelerates muscle…
- Trial name
- NCT06905964
- Testing
- Eccentric cycling exercise (ECC), Eccentric cycling exercise with assistive devices (ECA)
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
No Specific Conditions
Effects of Calisthenics and Life Kinetics on Reaction Time, Balance, and Swimming in Male Swimmers
This study investigates the effects of calisthenics and life kinetics exercises on reaction time, balance, and swimming performance in male swimmers.
- Trial name
- NCT07089563
- Testing
- Calisthenics Exercise Program, Life Kinetik Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bingol University
Stroke, Acute, Aphasia
Yes/No Questionnaire for Aphasic Patients (YNQ)
Quality of care depends strongly on oral communication with patients. Stroke patients, who have language disorders, have understanding difficulties, but also have difficulties in expressing their needs and in being understood.
- Trial name
- YNQ (NCT03257696)
- Testing
- Close-ended questionnaire
- Where
- France
- Volunteers
- 152 people
- Sponsor
- Groupe Hospitalier de la Rochelle Ré Aunis
Multiple Sclerosis
Managed Access Program (MAP) for Patients Diagnosed With Secondary Progressive Multiple Sclerosis With Active Disease
The purpose of this MAP Cohort Treatment Plan is to allow access to siponimod for eligible patients diagnosed with Secondary Progressive Multiple Sclerosis with active disease.
- Trial name
- NCT04540861
- Testing
- Siponimod
- Sponsor
- Novartis Pharmaceuticals
Emergency Department Triage
PREMEDICAL is a Clinical Investigation Aiming to Create a Data Basis That Can be Used to Enrich Information Collected in the Course of the Classic Patient Journey. Patients in the Emergency Department Will be Asked to Answer Patient-related and Symptom-oriented Questions. Minimum Age is 18 Years
The goal of this clinical investigation is to create a new type of data basis that can be used to enrich information collected in the course of the classic patient journey, such as medical history forms and discharge letters.
- Trial name
- NCT06933550
- Where
- Austria
- Volunteers
- 351 people
- Sponsor
- XUND Solutions GmbH
Renal Insufficiency, Chronic
Exploring the Impact of Nephropathy Formula No. 1 on Chronic Kidney Disease Patients
This study is a prospective randomized controlled trial, enrolling 70 patients with CKD stages 2-4, randomly divided into a control group and a treatment group, with 35 cases in each group.
- Trial name
- NCT06796660
- Testing
- Nephropathy Formula No. 1, integrated basic treatment for chronic kidney disease
- Where
- 3 sites in China
- Volunteers
- 70 people
- Sponsor
- Liu Zhanghong
Interstitial Cystitis, Bladder Diseases
Analysis of Expression of Nitric Oxide Syntheses and Their Functional Role in Human Urothelium
Painful bladder syndrome (PBS)/interstitial cystitis (IC) may be due to the actions of nitric oxide (NO) in the bladder tissue. NO is a gaseous substance with a very short half-life, synthesized by a group of NO-synthase-enzymes…
- Conditions
- Interstitial Cystitis, Bladder Diseases, Urinary Incontinence
- Trial name
- NCT00253006
- Testing
- Tissue examination for protein- and mRNA-expression of NO
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Copenhagen University Hospital at Herlev
Pain
Pre-operative Ketorolac Administration Has no Pre-emptive Analgesic Effect Following Total Abdominal Hysterectomy
Background: Experimental models using short duration noxious stimuli have led to the concept of pre-emptive analgesia. Ketorolac, a non-steroidal anti-inflammatory drug (NSAID), has been shown to have a post-operative narcotic…
- Trial name
- NCT02642718
- Testing
- Ketorolac Tromethamine
- Where
- 2 sites in Spain, United Kingdom
- Volunteers
- 48 people
- Sponsor
- Hospital Arquitecto Marcide
Respiratory Disease
Investigation of Inflammacheck to Measure Exhaled Breath Condensate Hydrogen Peroxide in Respiratory Conditions
People with lung conditions can suffer significantly with their symptoms and often require multiple trips to their GP or secondary care before a diagnosis is made.
- Trial name
- VICTORY (NCT04467190)
- Where
- United Kingdom
- Volunteers
- 425 people
- Sponsor
- Portsmouth Hospitals NHS Trust
Intellectual Disability
New Skills - No Scores Research Study
The purpose of this study is to test the feasibility of a physical literacy and food literacy intervention for children with Intellectual Disabilities ages 12-16 years.
- Trial name
- NCT04254666
- Testing
- Physical Literacy & Food Literacy Intervention.
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Massachusetts, Worcester
Patients With CLL Relapsing After an Initial Response (CR, PR ≥ 6 Months) Following no More Than Two Prior Treatment Lines; or, Patients With CLL Refractory (SD, PD or CR/PR < 6 Months) Following no More Than Two Prior Treatment Lines
GIMEMA CLL0809 Study (BendOfa)
In the last ten years there have been significant developments in CLL treatment. The advent of fludarabine, rituximab and the association of chemo-immunotherapy have substantially increased overall response rate, CR rate, time to…
- Trial name
- BendOfa (NCT01244451)
- Testing
- Ofatumumab, Bendamustine
- Where
- 32 sites in Italy
- Volunteers
- 49 people
- Sponsor
- Gruppo Italiano Malattie EMatologiche dell'Adulto
Shock, Systemic Inflammatory Response Syndrome
Safety and Efficacy of PHP in the Treatment of Shock Associated With Systemic Inflammatory Response Syndrome (SIRS)
To determine the safety and effectiveness of pyridoxylated hemoglobin polyoxyethylene conjugate (PHP) administered by continuous intravenous (IV) infusion in systemic inflammatory response syndrome (SIRS) patients with shock.
- Trial name
- NCT00021502
- Testing
- pyridoxalated hemoglobin polyoxyethylene conjugate (PHP)
- Volunteers
- 1,000 people
- Sponsor
- Apex Bioscience
Colonic Cancer, Unresectable Metastasis Originating in Colonic Cancer
Resection vs no Resection of the Primary in Colorectal Cancer With Unresectable Metastases
Main outcome: Assess the impact of cancer-related survival at 2 years in patients with unresectable metastatic colorectal cancer treated with chemotherapy alone versus surgery followed by chemotherapy. To assess overall survival.
- Trial name
- CCRe-IV (NCT02015923)
- Testing
- Colonic resection, Chemotherapy- scheme
- Where
- 22 sites in Spain
- Volunteers
- 107 people
- Sponsor
- Hospital Universitari de Bellvitge
Post-operative Pain
Open Thyroid Surgery With Pillow Versus no Pillow for Better Post-operative Outcomes
Primary: To compare the post-operative pain in patients with neck extension and without neck extension. Secondary: To determine the benefit of neck exposure and peri-operative complications, which include duration of operation…
- Trial name
- NCT01620151
- Testing
- Extended neck with standard support or pillow
- Where
- 2 sites in Hong Kong
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
The Study Focus on no Specific Condition
Interpretation of Health News Items Reporting Results of Pre-clinical Studies With or Without Spin by English-speaking Patients
The main objective of this study is to compare the interpretation of health news items reporting results of pre-clinical studies with or without spin (i.e., distortion of research results).
- Trial name
- NCT03094078
- Testing
- News item with spin, News item without spin
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris