Clinical trials: no Conditions
Enterobacteriaceae Infections
Study on Reduced Antibiotic Treatment vs Broad Spectrum Betalactam in Patients With Bacteremia by Enterobacteriaceae
The continuous increase in the bacterial resistance rate and the slow arrival of new therapeutic options have turned into an antibiotic crisis.
- Trial name
- SIMPLIFY (NCT02795949)
- Testing
- Antipseudomonal beta-lactam antibiotic, De-escalation(short-spectrum antibiotic)
- Where
- 21 sites in Spain
- Volunteers
- 344 people
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Patients Using Olanzapine, Quetiapine, Risperidone or Clozapine
No Guts No Glory Probiotics
The goal of this clinical trial is to learn if probiotics work to prevent or reduce metabolic side effects caused by antipsychotic medication in adults.
- Trial name
- NGNGP (NCT07606014)
- Testing
- Probiotic Formula
- Where
- 3 sites in Netherlands
- Volunteers
- 112 people
- Sponsor
- University Medical Center Groningen
There Are no Conditions Under Study. Healthy Volunteers
Eccentric Cycling Exercise With Assistive Devices on Mitochondrial Metabolism in T Lymphocyte
Eccentric cycling exercise can be a promising modality fwith lower respiratory demands and higher power output. Assistive devices like neuromuscular electrical stimulation (NMES) and compressive garment (CG) accelerates muscle…
- Trial name
- NCT06905964
- Testing
- Eccentric cycling exercise (ECC), Eccentric cycling exercise with assistive devices (ECA)
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Laparoscopic Technique no Switch to Open, Duration of Surgery
Clinical Trial Comparing Conventional and Robot-assisted(Da Vinci®)Laparoscopic Interventions for Hysterectomy
The aim of this study is to compare conventional with robot-assisted (Da Vinci®) laparoscopic hysterectomy regarding operating time peri-operative outcome and costs.
- Conditions
- Laparoscopic Technique no Switch to Open, Duration of Surgery, Intraoperative Complications, Postoperative Complications
- Trial name
- NCT00683293
- Testing
- Conventional Laparoscopic Hysterectomy, Robot-assisted (Da Vinci®) laparoscopic hysterectomy
- Where
- Switzerland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Kantonsspital Aarau
Safety Issues, Post Operative Pain
Safety and Efficacy of Wide Awake Local Anesthesia no Tourniquet Technique (WALANT) in Ankle Removal of Implant Surgery
Safety and efficacy of wide awake local anesthesia no torniquet technique (WALANT) in ankle surgery. Studying risks and benefits from WALANT compared to general anesthesia .
- Conditions
- Safety Issues, Post Operative Pain, Local Anesthetic Complication
- Trial name
- NCT05864664
- Testing
- Wide awake local anaesthesia no tourniquet technique
- Where
- Kuwait
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ali Lari
Opioid Use, Prescription Drug Abuse and Dependency
No Opioids PrescrIptions On Discharge After Surgery
Opioid analgesics are routinely prescribed for these patients for post-operative pain control. Even a short exposure to opioids in opioid-naïve patients following minor or major surgery has been associated with de novo habitual…
- Conditions
- Opioid Use, Prescription Drug Abuse and Dependency, Surgery, Postoperative Pain
- Trial name
- NOPIOiDS (NCT04469868)
- Testing
- No opioids at discharge
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- Albany Medical College
Patients Must Have Histologically or Cytologically Confirmed Locally Advanced or Metastatic NSCLC, EGFR Mutation-negative and ALK Rearrangement-negative
Efficacy and Safety of Ivonescimab Monotherapy as First-Line Treatment for PD-L1-Positive, Driver Gene-Negative, Locally Advanced or Metastatic NSCLC: A Multicenter, Prospective, Real-World Cohort Study
The treatment decisions, assessment schedule, and study procedures in this research will adhere to the routine clinical practice of each participating center.
- Conditions
- Patients Must Have Histologically or Cytologically Confirmed Locally Advanced or Metastatic NSCLC, EGFR Mutation-negative and ALK Rearrangement-negative, Eastern Cooperative Oncology Group Performance Status (ECOG PS) Score of 0 to 2, No Prior Systemic Therapy Received for the Advanced or Metastatic Disease
- Trial name
- PROMISE (NCT07696832)
- Testing
- Ivonescimab Injection
- Where
- China
- Volunteers
- 265 people
- Sponsor
- Guangdong Association of Clinical Trials
Hip Fractures
Patients With Acute Hip Fractures Will Receive Either the PENG Block or no Block Respectively.
Hip fracture pain is often severe and traditionally managed by systemic opioids which have increased risk of side effects in frail elderly patients.
- Trial name
- PENGBlock (NCT04996979)
- Testing
- Ropivacaine 0.5% Injectable Solution
- Where
- Singapore
- Volunteers
- 60 people
- Sponsor
- Singapore General Hospital
Healthy
Effect of a Proton Pump Inhibitor on Gleevec® in Healthy Volunteers
This is a research study that will investigate the effects of proton pump inhibitors (often used to treat stomach upset) on Gleevec® (a drug that is FDA-approved to treat some types of cancer) in healthy volunteers.
- Trial name
- NCT00446004
- Testing
- Imatinib Mesylate, Omeprazole
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
No Specific Diseases or Conditions Are Being Studied
THE EFFECT OF SIMULATION-BASED INTERPROFESSIONAL EDUCATION ON ATTITUDES TOWARD TEAMWORK
Our study aims to evaluate the effect of interprofessional simulation-based learning on teamwork attitudes among nursing and paramedic students during the patient handover process.
- Trial name
- NCT07655752
- Testing
- Simulation-Based Interprofessional Education Program
- Volunteers
- 56 people
- Sponsor
- Saglik Bilimleri Universitesi
Alcohol Consumption
Comparing the Efficacy of the Alcohol Help Centre and Check Your Drinking to a no Intervention Control Condition
Alcohol is one of the leading contributors to premature mortality and disability. Most people with alcohol problems will never seek treatment.
- Trial name
- NCT02977026
- Testing
- CYD, AHC
- Where
- Canada
- Volunteers
- 511 people
- Sponsor
- Centre for Addiction and Mental Health
Obesity, Bariatric Surgery
Preoperative Treatment With Noninvasive Intra-auricular Vagus Nerve Stimulation Pending Bariatric Surgery
Faced with the current obesity epidemic, new avenues of research into effective weight loss must be developed. Among the possible actions on obesity, vagus nerve stimulation has been shown in several studies to be effective in…
- Trial name
- OBESITE (NCT02648191)
- Testing
- NeuroCoach II Stim
- Where
- France
- Volunteers
- 27 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne