Clinical trials: no Conditions
No Disease or Condition is Being Studied, Stress Psychological
Supporting Secondary School Student Wellbeing Through a Mobile App and Wearable Biofeedback
This study aims to investigate the effects of an app and wearable device on the wellbeing of secondary school students. The app will offer support for stress management, sleep improvement, and time management.
- Conditions
- No Disease or Condition is Being Studied, Stress Psychological, Overall Wellness
- Trial name
- EWSSS (NCT06294210)
- Testing
- Mobile app and wrist-worn monitor
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Royal College of Surgeons, Ireland
Peripheral Arterial Disease, Intermittent Claudication
Systematic Review and Meta-Analysis on DCB vs. POBA in De-novo Femoropopliteal Disease
Restenosis is still an issue after endovascular revascularization for femoropopliteal occlusive disease. One approach to reduce the rates of restenosis and reintervention is local application of Paclitaxel with drug-coated…
- Trial name
- DOND (NCT02927574)
- Testing
- DCB, POBA
- Volunteers
- 1,400 people
- Sponsor
- Jena University Hospital
Dyspareunia, Urinary Incontinence
The Influence of Prepartum Perineal Training With the Epi-No Device on Pelvic Floor Function.
Perineal injury is the most common maternal obstetric complication associated with vaginal delivery (1). It is estimated that perineal lacerations of first and second degree occur in 38% of spontaneous vaginal deliveries in…
- Conditions
- Dyspareunia, Urinary Incontinence, Perineal Tear, Perineal Injury
- Trial name
- NCT05282160
- Testing
- Epino
- Where
- Brazil
- Volunteers
- 70 people
- Sponsor
- Universidade Estadual de Londrina
No Conditions
Health Management Training to Enhance Influenza Vaccine Immunogenicity
The goal of this study is to assess the immunogenicity of inactivated influenza vaccination (IIV) in healthy elderly volunteers aged 50 years and older receiving one of two different health management trainings.
- Trial name
- NCT01256515
- Testing
- Health Education, Health Education Training
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Microvascular Angina, Angina Pectoris
Changes in Ischemia and Angina Over 1 Year Among ISCHEMIA Trial Screen Failures With no Obstructive CAD on Coronary CT Angiography
Serial assessment of angina status and ischemia on stress echo over one year among patients with moderate ischemia on stress imaging and non-obstructive CAD on coronary CT angiography.
- Trial name
- CIAO (NCT02347215)
- Testing
- Quality of Life assessment, Stress imaging
- Where
- United States
- Volunteers
- 212 people
- Sponsor
- NYU Langone Health
ST-Elevation Myocardial Infarction (STEMI)
Reducing Slow/No-Reflow With Prophylactic High-Dose Intracoronary Adenosine Protocol in ST-Elevation Myocardial Infarction The REFLOW AMI Trial
The REFLOW AMI Trial aims to determine whether prophylactic high-dose intracoronary adenosine reduces slow-flow or no-reflow (SNR) in patients with ST-elevation myocardial infarction (STEMI) undergoing primary percutaneous…
- Trial name
- REFLOW AMI (NCT07898696)
- Testing
- Adenosine, Standard Treatment only
- Where
- 2 sites in Pakistan
- Volunteers
- 660 people
- Sponsor
- Prof Muzaffar Ali Zahidi
There is no Focus on Any Specific Condition
Antegrade Versus Retrograde IV for Blood Draws
The purpose of this study is to compare success rates of antegrade and retrograde intravenous (IV) catheters in their ability to aspirate 20 milliliter blood sample within a 2 minute time frame, 3 hours after initial insertion.
- Trial name
- NCT03533777
- Testing
- Peripheral intravenous catheter placement, Blood draw, Peripheral intravenous catheter
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Atrial Fibrillation, Atrial Flutter
Strategies for the Management of Atrial Fibrillation in patiEnts Receiving Dialysis 2 (SAFE-D2)
People receiving dialysis are more likely to develop atrial fibrillation (AF), an irregular heartbeat that increases the risk of stroke.
- Conditions
- Atrial Fibrillation, Atrial Flutter, End Stage Kidney Disease (ESRD), Dialysis Patients
- Trial name
- SAFE-D2 (NCT07779746)
- Testing
- Eliquis, No oral anticoagulation
- Volunteers
- 848 people
- Sponsor
- Unity Health Toronto
Postoperative Pain, Inguinal Hernia
No Opioids vs. Minimal Opioids Following Inguinal Hernia Repair
The investigators hypothesize that not prescribing opioids after uncomplicated, outpatient IHR will be non-inferior to prescribing opioids (5 tablets of Oxycodone, 5mg; or surgeon preference for intolerance) with respect to…
- Trial name
- NCT05929937
- Testing
- Opioids, No opioids
- Where
- 8 sites in United States, Canada
- Volunteers
- 904 people
- Sponsor
- Clayton Petro
Healthy, Human Papilloma Virus Infection
The Parents in Appalachia Receive Education Needed for Teen Project
This clinical trial studies an educational intervention for parents and providers in increasing human papillomavirus (HPV) vaccination rates in younger girls in Ohio Appalachia.
- Trial name
- PARENT (NCT01901770)
- Testing
- educational intervention
- Where
- United States
- Volunteers
- 624 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Hepatitis C, Chronic
A Study of Response-Guided Duration of Combination Therapy With GS-9451, Pegasys® and Copegus® With and Without Tegobuvir (GS-9190) in Previously Untreated Subjects With Genotype 1 Chronic Hepatitis C
This phase 2b study will evaluate the efficacy and safety of 16 and 24 weeks of a 4-drug regimen with GS-9451 and Tegobuvir and 24 weeks of a 3-drug regimen of GS-9451 without Tegobuvir, all with Peginterferon Alfa-2a (Pegasys®)…
- Trial name
- NCT01271790
- Testing
- Tegobuvir (GS-9190), GS-9451, Pegasys®
- Where
- 144 sites in United States, Austria and 6 more
- Volunteers
- 245 people
- Sponsor
- Gilead Sciences
Advanced and / or Metastatic Liposarcoma
Activity and Tolerability of Pazopanib in Advanced and/or Metastatic Liposarcoma. A Phase II Clinical Trial
Soft tissue and bone sarcomas are rare malignant tumors, which encompasses a large family of more than 50 histologically distinct tumor subtypes, all of which share a putative mesenchymal origin.
- Trial name
- NCT01692496
- Testing
- Pazopanib
- Where
- 15 sites in Germany, Spain
- Volunteers
- 52 people
- Sponsor
- Grupo Espanol de Investigacion en Sarcomas
Obesity, Overweight
Changing Eating Behavior Using Cognitive Training
Obesity is a global health problem. New and more efficient interventions are needed to overcome this disease. This randomized clinical trial aims to evaluate the effectiveness of changing eating behavior using cognitive training.
- Conditions
- Obesity, Overweight, Weight Loss
- Trial name
- NCT04450524
- Testing
- Hypnosis, Food inhibition training, Control
- Where
- 2 sites in Romania
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Babes-Bolyai University
No Condition, Brain GABA-B Function
GABA-B Receptor Function in Healthy Volunteers
There are several developing lines of evidence suggesting that brain receptors called GABA-B receptors play a significant role in addiction and its treatment.
- Trial name
- NCT01563224
- Testing
- Baclofen 10mg, Baclofen 60mg
- Where
- United Kingdom
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Auditory Hallucination, Hearing Voices When No One is Talking
Imagery Interventions for Auditory Vocal Hallucinations
This study explores the feasibility, acceptability, and effectiveness of four imagery intervention techniques (metacognitive imagery intervention, imagery rescripting, promoting positive imagery and competing imagery task) for…
- Conditions
- Auditory Hallucination, Hearing Voices When No One is Talking, Psychosis
- Trial name
- NCT05603260
- Testing
- Imagery intervention for voice hearing (meta-cognitive imagery rescripting), Imagery intervention for voice hearing (Imagery rescripting), Imagery intervention for voice hearing (promoting positive imagery de novo)
- Where
- Netherlands
- Volunteers
- 32 people
- Sponsor
- Hella Janssen
No Disease or Condition is Being Directly Studied, The Focus of the Study in Healthy Volunteers
The Effect of Osteopathic Manipulative Techniques on Human Tear Composition
This is a pilot study to determine if osteopathic manipulation can alter the concentration of proteins and lipids in human tears.
- Trial name
- NCT07633496
- Testing
- Osteopathic Manipulative Treatment
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Lake Erie College of Osteopathic Medicine
Myocardial Reperfusion Injury
Post Cond No Reflow
After having shown that postconditioning allowed a significant 36% reduction of infarct size as assessed by blood levels of myocardial enzymes in acute myocardial patients, the investigators objective is to assess the effect of…
- Trial name
- NCT01208727
- Testing
- postconditioning
- Where
- France
- Volunteers
- 44 people
- Sponsor
- Hospices Civils de Lyon
Healthy
Effect of Calcium on Tasigna Pharmacokinetics (PK) in Healthy Volunteers
This research study is being conducted through the University of Pittsburgh Cancer Institute (UPCI). It will evaluate the concentrations of Tasigna®, an oral drug used to treat some types of cancer, in the blood of healthy…
- Trial name
- NCT00732888
- Testing
- Nilotinib Hydrochloride, calcium carbonate
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Jan Beumer
Healthy
Bioequivalence Study of Fosinopril 40mg Tablets Under Fed Conditions
The objective of this study is to compare the relative bioavailability of fosinopril sodium 40 mg tablets (Ranbaxy Laboratories Limited, Lot No.
- Trial name
- NCT00776672
- Testing
- Fosinopril 40mg Tablets
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Ranbaxy Laboratories Limited
Liver Transplantation, Ischemia/Reperfusion Injury
Effect of Nitric Oxide (NO) on Ischemic/Reperfusion Injury During Extended Donor Criteria (EDC) Liver Transplantation
In this study, the researchers propose to investigate the efficacy of inhaled nitric oxide to prevent ischemia-reperfusion (I/R) hepatocyte injury in patients who receive extended donor criteria(EDC)liver grafts based on changes…
- Conditions
- Liver Transplantation, Ischemia/Reperfusion Injury, Oxidative Injury
- Trial name
- NCT00948194
- Testing
- Nitric Oxide
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- University of Colorado, Denver