Clinical trials: psoriasis
Psoriasis
Desoximetasone Spray 0.25%, Hypothalamic Pituitary Adrenal (HPA) Axis Study
The objective of this study is to evaluate the potential of desoximetasone 0.25% topical spray to suppress HPA axis function. The potential for adrenal suppression will be assessed following multiple dosing with Desoximetasone…
- Trial name
- NCT01043393
- Testing
- Desoximetasone 0.25% spray
- Where
- 3 sites in United States
- Volunteers
- 24 people
- Sponsor
- Sun Pharmaceutical Industries, Inc.
Psoriasis
A Multiple Dose Escalation Study of ASKP1240 in Subjects With Moderate to Severe Plaque Psoriasis
The purpose of this study is to explore the safety and tolerability of multiple doses of ASKP1240 compared to placebo and determine Pharmacokinetics and Pharmacodynamics in subjects with moderate to severe psoriasis.
- Trial name
- NCT01585233
- Testing
- ASKP1240
- Where
- 13 sites in Australia, Canada and 1 more
- Volunteers
- 60 people
- Sponsor
- Astellas Pharma Global Development, Inc.
Plaque Psoriasis
Pivotal Efficacy and Safety Registration Trial of FP187 in Moderate to Severe Plaque Psoriasis
The purpose of this trial is to investigate the efficacy and safety of different doses and dose administrations of FP187 compared to a placebo treatment in patients with moderate to severe plaque psoriasis.
- Trial name
- NCT01230138
- Testing
- FP187
- Where
- 2 sites in Germany
- Volunteers
- 252 people
- Sponsor
- Forward-Pharma GmbH
Psoriatic Arthritis (PsA)
Safety and Effectiveness of Abatacept in Psoriatic Arthritis Participants
The purpose of this study is a long-term, observational study of Abatacept in patients with Psoriatic Arthritis, a chronic inflammatory disorder.
- Trial name
- ALTEA (NCT03419143)
- Where
- Germany
- Volunteers
- 190 people
- Sponsor
- Bristol-Myers Squibb
Psoriasis and Psoriatic Arthritis
Bioequivalence Study of Two Products of Apremilast 30 mg Tablets in Healthy, Adult, Human Subjects
An open label, balanced, randomized, two-sequence, two-treatment, two-period, single oral dose, crossover, bioequivalence study in normal, healthy, adult, human subjects under fasting condition
- Trial name
- NCT06084663
- Testing
- Apremilast 30 mg Tablets, Otezla 30 mg film-coated tablets
- Where
- India
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Humanis Saglık Anonim Sirketi
Psoriasis Vulgaris
The Mediterranean Diet and Time-Restricted Eating Dietary Interventions for Psoriasis Study
The METRED-P study will test the feasibility of implementing a Mediterranean style diet and/or time-restricted eating as dietary patterns in individuals with psoriasis. This study will address the following research questions: 1.
- Trial name
- METRED-P (NCT05820698)
- Testing
- The Mediterranean style diet, The UK diet, Time-restricted eating
- Where
- United Kingdom
- Volunteers
- 22 people
- Sponsor
- King's College London
Psoriatic Arthritis
Study Evaluating Workload, Clinical and Therapeutic Management of Psoriatic Arthritis
In Spain, there is little data available concerning the evolution and treatment of Psoriatic Arthritis by rheumatologists and dermatologists.
- Trial name
- NCT00580632
- Volunteers
- 300 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Plaque Psoriasis
A Study of Ixekizumab (LY2439821) in Chinese Participants With Moderate-to-Severe Plaque Psoriasis
The purpose of this study is to determine the efficacy and safety of the study drug ixekizumab in Chinese participants with moderate-to-severe plaque psoriasis.
- Trial name
- NCT03364309
- Testing
- Ixekizumab
- Where
- 17 sites in China
- Volunteers
- 438 people
- Sponsor
- Eli Lilly and Company
Psoriasis Vulgaris
Incretin Effect in Patients With Psoriasis and Controls
To investigate the incretin effect and postprandial incretin responses in plasma in patients with psoriasis
- Trial name
- NCT06064084
- Testing
- Oral glucose tolerance test, Intravenous isoglycaemic glucose clamp, Liquid Mixed meal test
- Volunteers
- 24 people
- Sponsor
- University Hospital, Gentofte, Copenhagen
Psoriasis
Study to Evaluate Efficacy and Safety of MP1032 in Patients With Chronic Plaque Psoriasis
The primary objective of this trial is to evaluate the clinical efficacy and safety of two oral doses of MP1032 (150 mg bid and 300 mg bid) when taken for 12 weeks by patients with moderate-to-severe chronic plaque psoriasis.
- Trial name
- NCT03706209
- Testing
- MP1032
- Where
- 19 sites in Germany, Poland
- Volunteers
- 155 people
- Sponsor
- MetrioPharm AG
Arthritis, Rheumatoid, Spondyloarthritis, Axial
Biologic Treatment Registry Across Canada
This registry is a multi-center, prospective, longitudinal, observational program that will gather and analyse data on participants treated with infliximab, golimumab, golimumab Intravenous (I.V) or ustekinumab.
- Conditions
- Arthritis, Rheumatoid, Spondyloarthritis, Axial, Arthritis, Psoriatic
- Trial name
- BioTRAC (NCT00741793)
- Where
- Canada
- Volunteers
- 2,821 people
- Sponsor
- Janssen Inc.
Psoriasis
Study of the Efficacy of Cloderm® Cream in the Treatment of Moderate Plaque Psoriasis
The purpose of this study is to determine whether Cloderm Cream is effective for topical treatment of moderate psoriasis over 28 days.
- Trial name
- NCT01714544
- Testing
- Cloderm Cream
- Where
- 5 sites in United States
- Volunteers
- 60 people
- Sponsor
- Promius Pharma, LLC
Psoriasis Vulgaris, Topical Administration
Efficacy and Safety of a Botanical Total Coumarin (TC) Cream in Treating Patients With Psoriasis Vulgaris (PLANTCOAT-IIb Trial)
A Double-Blind, Randomized, Placebo-Controlled, Multicenter Phase IIb Clinical Trial to Evaluate the Efficacy and Safety of a Botanical Total Coumarin Cream (TC) in Treating Patients with Psoriasis Vulgaris
- Trial name
- PLANTCOAT-IIb (NCT03372811)
- Testing
- Total coumarin (TC) cream, Vehicle
- Where
- 2 sites in United States
- Volunteers
- 88 people
- Sponsor
- Psoriasis Research Institute of Guangzhou
Psoriasis
A Study to Assess the Clinical Profile of Patients in Spain With Moderate to Severe Psoriasis.
The purpose of this study is to assess the clinical profile of patients with moderate to severe psoriasis in Spain. The primary objective is to analyze the clinical profile of patients with moderate to severe psoriasis, as…
- Trial name
- NCT01262534
- Testing
- Clinical profile of patients, Patient Preferences about treatment, Quality of Life
- Volunteers
- 1,042 people
- Sponsor
- Janssen-Cilag, S.A.
Effects, Drug Side
An Investigational Study to Evaluate Experimental Medication SYHX1901 Tablets With Moderate to Severe Plaque Psoriasis
The purpose of this study is to evaluate the efficacy and safety of different doses of SYHX1901 tablets in the treatment of moderate to severe plaque psoriasis in order to select doses for further clinical trials.
- Trial name
- NCT05858047
- Testing
- SYHX1901
- Where
- China
- Volunteers
- 93 people
- Sponsor
- CSPC Ouyi Pharmaceutical Co., Ltd.
Psoriasis
PPD™ CorEvitas™ Psoriasis (PSO) Rapid Response Non-Interventional Study
This is a 16-week prospective, single-arm cohort, study of patients initiating advanced therapy for the treatment of moderate-to-severe plaque PSO.
- Trial name
- NCT07615712
- Testing
- Observational (Non-Interventional) Registry
- Where
- United States
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- CorEvitas
Psoriatic Arthritis
National Psoriasis Foundation - Dendritic Cell-Specific Transmembrane Protein (DC-Stamp) Biomarker Study
The purpose of this study is to determine whether DC-STAMP, a protein on the surface of osteoclast precursors (OCPs), can be used as a biologic marker in Psoriatic Arthritis (PsA).
- Trial name
- NCT01123265
- Testing
- Methotrexate, Anti-TNF
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Rochester
Plaque Psoriasis
Bee Venom Phonophoresis on Mild to Moderate Localized Plaque Psoriasis on Knee Joint
Chronic plaque psoriasis, or psoriasis vulgaris, is a chronic inflammatory skin disease characterized by well demarcated, erythematous, scaly plaques on the extensor surfaces of the body and scalp.
- Trial name
- NCT06106230
- Testing
- Bee venom phonophoresis
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- MTI University
Psoriasis Vulgaris
LEO 22811 - A Phase 1, Double-Blind, Placebo-controlled, Single and Multiple Oral Dose Study in Healthy Subjects
The purpose of this first-in-man trial is to determine the safety and tolerability of ascending single and multiple doses of LEO 22811 in healthy male subjects as well as to determine the safety and tolerability of single oral…
- Trial name
- NCT00833872
- Testing
- LEO 22811
- Where
- United Kingdom
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- LEO Pharma
Psoriasis
Comparative Efficacy of Alpha Hydroxy Acids With and Without Nanocarriers Versus Calcipotriol Plus Betamethasone in Treatment of Plaque Psoriasis
The aim of this double blind comparative clinical study is to evaluate the efficacy of AHAs combined with nanocarriers and their use as a non steroidal alternative drug for long term management of plaque psoriasis
- Trial name
- NCT07816575
- Testing
- Alpha Hydroxy Acids with nanocarriers, Alpha Hydroxy Acids only., Calcipotriol plus betamethasone
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Al-Azhar University
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