Clinical trials: psoriasis
Plaque Psoriasis
Plaque Psoriasis Study in Pediatric Subjects
The purpose of this study is to compare the safety, efficacy and calcium metabolism of up to 8 weeks of treatment with calcitriol 3 mcg/g ointment versus its vehicle, when used twice daily, without occlusion, to treat children…
- Trial name
- NCT02186665
- Testing
- calcitriol ointment
- Where
- 34 sites in United States, Belgium and 5 more
- Volunteers
- 19 people
- Sponsor
- Galderma R&D
Psoriasis
Olux E Foam and Sorilux Foam Combination Therapy for the Maintenance of Treatment Response in Patients With Moderate Plaque Psoriasis
The purpose of the study is to investigate if combined use of OLUX-E™ Foam and SORILUX Foam may help "maintain" the therapeutic benefit that is achieved with OLUX-E™ Foam in the treatment of moderate plaque psoriasis.
- Trial name
- NCT01745133
- Testing
- vehicle foam, calcipotriene, calcipotriene + clobetasol propionate
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Leon Kircik, M.D.
Psoriasis
A Study of the Safety and Efficacy of Infliximab in Patients With Psoriasis
The purpose of this study is to determine if infliximab (anti-TNF) is effective in the treatment of plaque psoriasis.
- Trial name
- NCT00106834
- Testing
- Infliximab
- Volunteers
- 378 people, healthy volunteers welcome
- Sponsor
- Centocor, Inc.
Lymphoma
Serum Protein Patterns in Participants With Mycosis Fungoides/Cutaneous T-Cell Lymphoma, Psoriasis, or Normal Skin
RATIONALE: The presence of specific serum proteins may allow a doctor to determine if a patient has mycosis fungoides/cutaneous T-cell lymphoma.
- Trial name
- NCT00066664
- Testing
- proteomic profiling
- Where
- 4 sites in United States
- Volunteers
- 423 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Psoriasis (PsO), Enthesitis
A Prospective Study to Assess the Efficacy of IL-17 Inhibitors on Subclinical Enthesitis in Patients With Moderate to Severe Psoriasis Based on Power Doppler (PD) Ultrasonography (PDUS)
It is an observational, single-center, prospective, exploratory, open-label study to assess the efficacy and safety of IL-17 inhibitors on subclinical enthesitis in patients with moderate to severe psoriasis with subclinical…
- Conditions
- Psoriasis (PsO), Enthesitis, Psoriasis Arthritis, Secukinumab
- Trial name
- NCT06987292
- Testing
- IL-17i
- Where
- 2 sites in China
- Volunteers
- 50 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Psoriatic Arthritis, HLA b Leader
HLA B Leader in Patients With Psoriatic Arthritis
Psoriatic arthritis (PsA), a chronic immune-mediated heterogeneous inflammatory disease characterized by musculoskeletal inflammation (arthritis, enthesitis, spondylitis and dactylitis), usually occurs in patients with psoriasis.
- Conditions
- Psoriatic Arthritis, HLA b Leader, HLA B27
- Trial name
- HLABLRP (NCT07718815)
- Testing
- blood test
- Where
- France
- Volunteers
- 658 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Psoriasis
The Efficacy and Safety of Adding Methotrexate to Etanercept in Psoriasis
The purpose of this study is to evaluate the efficacy of adding methotrexate to etanercept compared with etanercept monotherapy as measured by the percentage of participants achieving a 75% improvement from baseline in the…
- Trial name
- NCT01001208
- Testing
- Methotrexate, Etanercept
- Volunteers
- 478 people
- Sponsor
- Amgen
Psoriasis
Study to Help Understand the Action of the Drug Etanercept for the Adult Patient With Psoriasis
The investigator's laboratory is studying a skin disease known as psoriasis. The purpose of this protocol is to study the action and the effects of Etanercept, on psoriasis.
- Trial name
- NCT00116181
- Testing
- Etanercept
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Rockefeller University
Chronic Plaque Psoriasis
Efficacy Study of CDP870 in Subjects With Chronic Plaque Psoriasis Who Are Candidate for Systemic Therapy and/or Phototherapy/Photochemotherapy
A study to assess the safety and efficacy of 2 different doses of CDP870 versus placebo, administered during 12 weeks, to patients suffering from moderate to severe chronic plaque psoriasis, extended by a 12 to 24 week follow-up.
- Trial name
- NCT00245765
- Testing
- Certolizumab Pegol
- Where
- 15 sites in France, Germany
- Volunteers
- 176 people
- Sponsor
- UCB Pharma
Chronic Plaque Psoriasis
Open-Label Extension Trial of PDE4 Inhibition With Roflumilast for the Management of Plaque Psoriasis
This study will assess the safety and efficacy of ARQ-151 cream applied once a day for 24 weeks by subjects with chronic plaque psoriasis
- Trial name
- DERMIS-OLE (NCT04286607)
- Testing
- Topical roflumilast
- Where
- 85 sites in United States, Canada and 1 more
- Volunteers
- 337 people
- Sponsor
- Arcutis Biotherapeutics, Inc.
Plaque Psoriasis
Multiple-Dose Pharmacokinetics and Potential for Adrenal Suppression Following Treatment With Halobetasol Spray in Patients With Plaque Psoriasis
This is an open-label, safety study designed to assess the multiple-dose pharmacokinetics and potential for adrenal suppression following topical treatment with halobetasol propionate 0.05% spray applied twice-daily in adult…
- Trial name
- NCT03298581
- Testing
- Halobetasol Propionate
- Sponsor
- Sun Pharmaceutical Industries Limited
Quality of Life
Patient Centered Care Situation and Health-related Quality of Life by Patients With Psoriasis, Urticaria or Lupus
This study is based on a survey about the patient centered care situation and health-related quality of life of patients with diagnoses Psoriasis, Urtikaria or Lupus erythematodes.
- Trial name
- PUL (NCT03324919)
- Testing
- HRQL
- Where
- Germany
- Volunteers
- 220 people
- Sponsor
- University Hospital Regensburg
Psoriasis
A Study to Evaluate the Pharmacokinetics, Safety and Tolerability of ABBV-157 in Healthy Volunteers and in Participants With Chronic Plaque Psoriasis
This is a study to evaluate pharmacokinetics (PK), safety and tolerability of ABBV-157 in healthy volunteers and in participants with chronic plaque psoriasis, and to evaluate the efficacy of ABBV-157 in the participants with…
- Trial name
- NCT03922607
- Testing
- ABBV-157
- Where
- 10 sites in United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- AbbVie
Plaque Psoriasis
Moving Cupping for Plaque Psoriasis: a Randomized Controlled Trial
The purpose of this study was to provide evidence support for the effectiveness and safety of moving cupping therapy for plaque psoriasis through clinical studies.
- Trial name
- NCT03952676
- Testing
- Moving cupping
- Where
- 5 sites in China
- Volunteers
- 122 people
- Sponsor
- Shanghai Yueyang Integrated Medicine Hospital
Acne, Actinic Keratosis
Potential Research Study Participant Registry
The purpose of the potential research study participant registry is to keep potential research subjects informed about any future research studies in which they may meet the criteria for enrollment.
- Conditions
- Acne, Actinic Keratosis, Dysplastic Nevi, Eczema
- Trial name
- NCT00710489
- Where
- United States
- Volunteers
- 265 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Psoriasis
An Investigational Study of Cyclosporine on Experimental Medication BMS-986165 in Healthy Male Participants
This is an investigational study of Cyclosporine on the experimental medication BMS-986165 in healthy male participants.
- Trial name
- NCT03419910
- Testing
- BMS-986165, Cyclosporine
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb
Plaque Psoriasis
Study to Evaluate PF-04965842 in Patients With Moderate to Severe Psoriasis
Study B7451005 is a Phase 2 study which will assess the efficacy and safety of PF-04965842 in patients with moderate to severe psoriasis.
- Trial name
- NCT02201524
- Testing
- PF-04965842
- Where
- 45 sites in United States, Canada
- Volunteers
- 59 people
- Sponsor
- Pfizer
Psoriasis, Alopecia Areata
Improving Disease Severity
Phototherapy, including ultraviolet B (UVB) and ultraviolet A (UVA) light, has been used to treat a number of dermatologic conditions.
- Conditions
- Psoriasis, Alopecia Areata, Polymorphous Light Eruption
- Trial name
- NCT05391178
- Testing
- Lumiton yarn sleeve, Lumiton yarn hat, Lumiton yarn shirt
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Wake Forest University Health Sciences
Psoriasis Palm & Soles
Treatment of Palmoplantar Psoriasis With Low Doses Interferential Current
Interferential current has shown promising results for treating psoriasis with a good tolerance. Prospective randomized studies versus placebo are required to confirm the interest of such an approach.
- Trial name
- NCT01765985
- Testing
- PSORIAMED
- Where
- France
- Volunteers
- 36 people
- Sponsor
- Pr PASSERON
Psoriasis, Psoriatic Arthritis
Genetic Variation in TRAF3IP2 (rs13190932)
Psoriasis is an immune-mediated inflammatory disease that is highly prevalent worldwide, affecting approximately 2-3% of the world population.
- Trial name
- NCT07086924
- Testing
- Methotrexate
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- South Valley University