Clinical trials: stroke
Chronic Stroke
Constraint Induced Movement Therapy and Bilateral Training in Chronic Stroke
Stroke is a leading cause of long-term disability, with upper limb spasticity and impaired hand function being common problems in the chronic phase.
- Trial name
- CIMT-BT (NCT07378774)
- Testing
- CIMT, bilateral training
- Where
- Pakistan
- Volunteers
- 112 people
- Sponsor
- Zikra Azhar
Stroke, Brachial Plexus Injury
Retrospective Study on Myoelectric Elbow-Wrist-Hand Orthosis User Outcomes
The objective of this study is to retrospectively evaluate the outcomes and clinical benefits provided by this brace to adult patients with upper limb impairment or paralysis due to brachial plexus, stroke (CVA), spinal cord…
- Conditions
- Stroke, Brachial Plexus Injury, Spinal Cord Injuries, Neurological Disease
- Trial name
- NCT05575674
- Testing
- Myoelectric Elbow-Wrist-Hand Orthosis
- Where
- 3 sites in United States
- Volunteers
- 21 people
- Sponsor
- Myomo
Stroke
A Study of Plasmatic Concentrations of Endothelin-1 (ET1), Atrial Natriuretic Peptide (ANP) and Brain Natriuretic Peptide (BNP) in Acute Ischemic Stroke.
A study of plasmatic concentrations of endothelin-1 (ET1), atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP) in acute ischemic stroke.
- Trial name
- NCT00213785
- Where
- France
- Volunteers
- 14 people
- Sponsor
- University Hospital, Strasbourg, France
Stroke
Effectiveness of Epley Maneuver Versus Semont Maneuver on Dizziness and Balance in Stroke Survivors With Posterior Canal BPPV
This randomized controlled trial aims to compare the effectiveness of the Epley maneuver and the Semont maneuver in reducing dizziness and improving balance in stroke survivors diagnosed with posterior canal benign paroxysmal…
- Trial name
- NCT07887191
- Testing
- Epley Maneuver, Semont Maneuver
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Ibadat International University, Islamabad
Stroke
Noninvasive Vagal Nerve Stimulation for Arm Recovery After Stroke
This study will find out whether electrical stimulation of a nerve called the "vagus" nerve is acceptable for patients undergoing physiotherapy for arm weakness after a stroke.
- Trial name
- NCT03170791
- Testing
- vagal nerve stimulation intervention
- Where
- United Kingdom
- Volunteers
- 5 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Stroke, Acute
Optimized C-arm Cone Beam CT for the Endovascular Treatment (EVT) of Acute Stroke
When it comes to acute stroke, everyone deserves the best care. Today, more patients can benefit from endovascular treatment (EVT) in a comprehensive stroke center.
- Trial name
- ASO-AVC (NCT04774510)
- Testing
- Diagnostic Test: optimized C-Arm Cone Beam Computed Tomography
- Where
- France
- Volunteers
- 38 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Transient Ischemic Attack
Telestroke for Comprehensive Transient Ischemic Attack Care in Acute Stroke Ready Hospitals
TELECAST-TIA is a prospective single-center study evaluating guideline-based transient ischemic attack (TIA) treatment at an Acute Stroke Ready Hospital (ASRH) pre- and post-initiation of a specialist telestroke inpatient…
- Trial name
- TELECAST-TIA (NCT03724110)
- Testing
- Telestroke
- Where
- 5 sites in United States
- Volunteers
- 300 people
- Sponsor
- University of Minnesota
Ischemic Stroke, Acute Stroke
Continuous Dual Aspiration Technique With Zoom System for Stroke
This study is designed to evaluate the effectiveness, safety and clinical performance of ADAPT 2.0, first-line aspiration neurothrombectomy with Zoom System with Continuous Dual Aspiration Technique (CDAT).
- Trial name
- ADAPT 2 0 (NCT07491952)
- Testing
- Zoom System
- Where
- 25 sites in United States
- Volunteers
- 750 people
- Sponsor
- Imperative Care, Inc.
Ischemic Stroke
Evaluate the Efficacy of Bu-Yang- Huan-Wu Tang（BYHWT）on Ischemic Stroke
Clinical trial; Ischemic stroke; Bu-Yang-Huan-Wu Tang （BYHWT）; Gait parameter; Quality of life Stroke is the third of ten causing death disease constantly, and it also is third of consuming healthy insurance budget.
- Trial name
- NCT02150252
- Testing
- Bu-Yang-Huan-Wu Tang
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- China Medical University Hospital
Intracranial Pressure, Traumatic Brain Injury
NIMI-NICU: Non Invasive Monitoring of the Intracranial Pressure - NeuroIntensive Care Unit
In clinical practice, intracranial pressure (ICP) represents a key parameter for diagnosing and treating several conditions. Physicians having to manage cases of head trauma, stroke and hydrocephalus need to assess the time…
- Conditions
- Intracranial Pressure, Traumatic Brain Injury, Stroke, Intracranial Hemorrhages
- Trial name
- MINIPIC REA (NCT01685476)
- Testing
- Echodia® hand-held equipment
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Clermont-Ferrand
Stroke
Clinical Biological and Pharmacological Factors Influencing Stroke Outcome
In a previous suty, we have demonstrated that prior transient ischemic attack, treatment lipid-lowering drug or physical activity are associated to a better outcome of stroke.
- Trial name
- biostroke (NCT00763217)
- Where
- France
- Volunteers
- 550 people
- Sponsor
- University Hospital, Lille
Severe Dementia, Stroke
Efficacy of Defurocumarinized Bergamot in the Treatment of Agitation in Severe Dementia Patients.
This study evaluates the efficacy of defurocumarinized bergamot in the treatment of agitation in severe dementia patients. Bergamot essential oil (BEO), able to modulate the endogenous, peripheral and central opioid system…
- Trial name
- BEO (NCT04321889)
- Testing
- defurocumarinized bergamot loaded in a nanotechnological essential oil release system
- Volunteers
- 134 people
- Sponsor
- S.Anna Rehabilitation Institute
Ischemic Stroke
Laser Acupuncture Improves Constipation in Patients Hospitalized for Stroke During the COVID-19 Pandemic
With the aging of today's population, stroke is the top three causes of disability and death among people over the age of 60 in the world.
- Trial name
- NCT05002348
- Testing
- Laser acupoint stimulation(Laser pen)
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Yueh-Lin Hsu
Disorder of Consciousness, Traumatic Brain Injury
Sub-study of the NEURODOC Project : Neurophysiological Evaluation of a Routine Care Open Label tDCS Session
Limited treatments are available to improve consciousness in severely brain injured patients. Transcranial Direct Current stimulation (tDCS) is one of the few therapeutics that showed evidence of efficacy to increase level of…
- Conditions
- Disorder of Consciousness, Traumatic Brain Injury, Anoxic Brain Injury, Stroke
- Trial name
- Neurodoc (NCT04035655)
- Testing
- Coma Recovery Scale - revised, Electrophysiological recordings
- Where
- France
- Volunteers
- 66 people
- Sponsor
- Groupe Hospitalier Pitie-Salpetriere
Hemiplegia
HEMITOX : Effect of Botulinum Toxin Injections on Motor and Functional Ability of Upper Limb in Adults at Earlier Phases of Spastic Hemiplegia After Stroke
Botulinum toxin produced beneficial effects in spasticity in the hemiplegic upper limb. This study will test if botulinum toxin injections at earlier phases (<or = 3 months) in spasticity improve functional and motor tests…
- Trial name
- NCT00276185
- Testing
- Time delay treatment of botulinum toxin
- Where
- France
- Volunteers
- 180 people
- Sponsor
- University Hospital, Clermont-Ferrand
Foramen Ovale, Patent
Risk of Ischaemic Stroke After Pulmonary Embolism in Patients With and Without Patent Foramen Ovale
stroke's risk is increased in patients with pulmonary embolism and PFO compared to patients without PFO. Does this increased risk persist years after pulmonary embolism ?
- Trial name
- EPIC-FOPCohort (NCT04987008)
- Where
- 3 sites in France
- Volunteers
- 53 people
- Sponsor
- University Hospital, Brest
Stroke, Aphasia
Adjustment With Aphasia After Stroke: SUPERB
Aims: This exploratory trial will: 1. Explore the feasibility of a definitive/phase III RCT on clinical and cost-effectiveness of peer-befriending for people with aphasia post-stroke. 2.
- Trial name
- SUPERB (NCT02947776)
- Testing
- PEER, USUAL
- Where
- 5 sites in United Kingdom
- Volunteers
- 62 people
- Sponsor
- City, University of London
Stroke, Ischemic
Safety and Efficacy of Therapeutic Hypothermia in Acute Ischemic Stroke
Therapeutic hypothermia (TH) in stroke has demonstrated robust neuroprotection in animals especially after ischemia-reperfusion injury, but its safety and efficacy remain controversial.
- Trial name
- THIS (NCT05779176)
- Testing
- Therapeutic hypothermia
- Where
- China
- Volunteers
- 252 people
- Sponsor
- RenJi Hospital
Ischemic Stroke, Thrombolysis
Hypothermia in Acute Ischemic Stroke - Surface Versus Endovascular Cooling (HAIS-SE)
HAIS-SE is evaluating for the first time ever in a randomized controlled trial efficacy, tolerability, practicability and safety of endovascular versus surface cooling in awake stroke patients.
- Conditions
- Ischemic Stroke, Thrombolysis, Hypothermia
- Trial name
- HAIS-SE (NCT01665885)
- Testing
- ZOLL Thermogard XP, BARD/Medivance Arctic Sun 5000
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- University Hospital Heidelberg
Acute Ischemic Stroke, Clopidogrel Resistance
Precision Antiplatelet Therapy Guided by Platelet Aggregation Function in Patients With Acute Ischemic STROKE
The objective of this clinical trial is to evaluate the efficacy and safety of platelet aggregation function - guided precision anti - platelet therapy in patients with acute cerebral infarction.
- Trial name
- PATH STROKE C (NCT06853535)
- Testing
- The ticagrelor, The Clopidogrel
- Where
- China
- Volunteers
- 5,138 people
- Sponsor
- Sichuan Provincial People's Hospital
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