Clinical trials: stroke
Stroke, Stroke, Acute
Earlier Mobilization Post Acute Thrombolysis
This is a phase III trial trying to determine whether 12-hour bed rest following IV thrombolysis therapy (i.e. tPA) for ischemic stroke is non-inferior to 24-hour bed rest by measure of outcomes on the modified Rankin Scale (mRS)…
- Conditions
- Stroke, Stroke, Acute, Stroke, Ischemic
- Trial name
- EMPATHY-I (NCT04153942)
- Testing
- Mobilization
- Sponsor
- Brian Silver
Atrial Fibrillation
Global Anticoagulant Registry in the Field
The Global Anticoagulant Registry in the FIELD-Atrial Fibrillation (GARFIELD-AF Registry) is a non-interventional, observational study that characterized a global population of non-valvular atrial fibrillation patients.
- Trial name
- GARFIELD-AF (NCT01090362)
- Where
- 35 sites in United States, Argentina and 33 more
- Volunteers
- 57,250 people
- Sponsor
- Thrombosis Research Institute
Lateral Medullary Syndrome, Deglutition Disorders
The Motor Imagery Based on Action Observation Treatment on Dysphagia in Wallenberg Syndrome
The goal of this clinical trial is to learn about on dysphagia in wallenberg syndrome. The main questions it aims to answer are: the efficacy of motor imagery based on action observation treatment in the rehabilitation of…
- Trial name
- NCT06224686
- Testing
- conventional dysphagia treatment, motor imagery based on action observation treatment
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Le Wang
Atrial Fibrillation, Stroke
Apixaban for the Reduction of Thrombo-Embolism in Patients With Device-Detected Sub-Clinical Atrial Fibrillation
This study aims to determine if treatment with apixaban, compared with aspirin, will reduce the risk of ischemic stroke and systemic embolism in patients with device-detected sub-clinical atrial fibrillation and additional risk…
- Trial name
- ARTESiA (NCT01938248)
- Testing
- Apixaban, aspirin
- Where
- 130 sites in United States, Belgium and 11 more
- Volunteers
- 4,012 people
- Sponsor
- Population Health Research Institute
Endocarditis, Stroke
Evaluation of the Prognostic Impact of a Neuro-vascular Examination Associated With Cerebral MRI in the Acute Phase of Infectious Endocarditis
Infectious endocarditis (IE) is a serious condition with an annual incidence of 3 to 10 per 100,000 people. Brain infarctions complicate approximately 20-40% of endocarditis.
- Trial name
- POMPEI (NCT05378126)
- Testing
- Neurological assessment
- Where
- France
- Volunteers
- 29 people
- Sponsor
- Hospices Civils de Lyon
Hemorrhage; Intracerebral, Nontraumatic, Ischemic Strokes
Effect of Ischemic Strokes on Recovery From Intracerebral Hemorrhages
Intracerebral hemorrhage (ICH) occurs when small arteries in the brain rupture due to weakening by age, high blood pressure, and/or elevated cholesterol.
- Conditions
- Hemorrhage; Intracerebral, Nontraumatic, Ischemic Strokes, Diffusion Weighted Imaging Lesions
- Trial name
- NCT01417117
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Rush University Medical Center
Stroke Sequelae, Neuropathic Pain
Prevalence of Central Neuropathic Pain After a Stroke in Patients Attending Post-stroke Consultations in the Île-de-France Region
Post-stroke pain is common, affecting 15-50% of patients and significantly impacting their quality of life, rehabilitation, and functional recovery.
- Trial name
- AVCD (NCT06813391)
- Testing
- Patient Reported Outcome (PRO)
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Stroke
Effect of Combining Central and Peripheral Cutaneous Electrical Stimulation on Lower Limb Motor Function in People With Stroke
This study aims to evaluate the effectiveness of transcranial direct current stimulation (tDCS) and transcutaneous electrical nerve stimulation (TENS) in augmenting the efficacy of the lower limb task-oriented training in people…
- Trial name
- NCT06838013
- Testing
- Transcranial direct current stimulation (tDCS), Bilateral Transcutaneous electrical nerve stimulation (Bi-TENS), Lower-limb task-oriented training
- Where
- Hong Kong
- Volunteers
- 92 people
- Sponsor
- The Hong Kong Polytechnic University
Stroke
The Neurotrophic Effects of Lithium Carbonate Following Stroke: A Feasibility Study
Stroke is the leading cause of adult disability and the third leading cause of death in Canada. Most stroke survivors live with residual impairments that diminish independence and quality of life.
- Trial name
- NCT01112813
- Testing
- Lithium Carbonate
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- Sunnybrook Health Sciences Centre
Stroke
A Cognitive-Augmented Mobility Program
This project will combine best-evidence gait and mobility training with best evidence cognitive strategy training to produce a new cognitive-augmented mobility intervention that is expected to optimize long-term functional…
- Trial name
- CAMP (NCT03683160)
- Testing
- Cognitive Augmented Mobility Program
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Sunnybrook Health Sciences Centre
Stroke
Is Robot-Assisted Therapy Effective for the Upper Extremity Following a Stroke
The aim of this study was to investigate the effects on upper-limb motor function of the addition of robotic rehabilitation (RR) and conventional rehabilitation (CR) treatments to intensive trunk rehabilitation (ITR).
- Trial name
- NCT05559385
- Testing
- Robot-Assissted Therapy, Conventional Rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 41 people
- Sponsor
- Emresenocak
Stroke, Ischemic
SYNCHRONISE: LVO Triage Timing and Outcome Study
The objective of this study is to evaluate the impact of Viz LVO in hospital systems with non-interventional and interventional (spoke and hub) stroke centers on the timing and outcomes of patients with suspected acute ischemic…
- Trial name
- NCT04608617
- Testing
- Viz LVO (De Novo Number DEN170073), Baseline Effectiveness Cohort
- Where
- 3 sites in United States
- Volunteers
- 600 people
- Sponsor
- Viz.ai, Inc.
Stroke
Siblings With Ischemic Stroke Study
The purpose of this study is to find the genes that increase the risk of developing an ischemic stroke using DNA samples collected from concordant (stroke-affected) sibling pairs.
- Trial name
- SWISS (NCT00108940)
- Where
- 32 sites in United States, Canada
- Volunteers
- 900 people
- Sponsor
- Mayo Clinic
Stroke, Transient Ischemic Attack
A Person-centred Care Transition Support for People With Stroke/TIA
The goal of this clinical trial is to test a person-centred care transition support in people with stroke/TIA. The main questions it aims to answer are: Does a multi-component care transition intervention have an effect on…
- Trial name
- Missing Link (NCT05646589)
- Testing
- Person-centred care transition support, Regular care transition
- Where
- 3 sites in Sweden
- Volunteers
- 213 people
- Sponsor
- Karolinska Institutet
Stroke
Outcome of Intravenous Thrombolysis for Stroke Patients in the 3-4.5 Hour Time Window
The time window for intravenous recombinant tissue plasminogen activator treatment in ischemic stroke patients has been extended to 4.5h.
- Trial name
- NCT01770197
- Testing
- IV rt-PA
- Volunteers
- 200 people
- Sponsor
- Wuhan General Hospital of Guangzhou Military Command
Anxiety Disorders, Stroke
Treating Anxiety After Stroke (TASK)
The TASK (Treating Anxiety after StroKe) trial is a feasibility randomized controlled trial. It aims to evaluate the feasibility of i) web-enabled trial procedures, and ii) the TASK intervention in stroke and TIA patients
- Conditions
- Anxiety Disorders, Stroke, Transient Ischemic Attack
- Trial name
- TASK (NCT03439813)
- Testing
- TASK-CBT, TASK-Relax
- Where
- United Kingdom
- Volunteers
- 27 people
- Sponsor
- University of Edinburgh
Stroke
Treadmill Training With Kinesiotaping Affects Balance and Gait in Chronic Stroke Patients
The goal of this clinical trial is to determine the effects of treadmill training with and without trunk kinesiotaping on balance and gait of chronic stroke patients.
- Trial name
- NCT05878613
- Testing
- treadmill training with KT group (TTKT group), treadmill training without KT group (TT group)
- Where
- Pakistan
- Volunteers
- 22 people
- Sponsor
- Riphah International University
Ischemic Stroke, Stroke, Acute
Tenecteplase in Wake-up Ischaemic Stroke Trial
Stroke is a leading causes of death and disability. At least 20% of strokes occur during sleep, so- called 'wake up stroke'. Thrombolysis with the clot-busting drug alteplase is effective for acute ischaemic stroke, provided that…
- Trial name
- TWIST (NCT03181360)
- Testing
- Tenecteplase, Control
- Where
- 83 sites in United States, Denmark and 9 more
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University Hospital of North Norway
Stroke, Acute
Tenecteplase Treatment in Ischemic Stroke Registry
The Tenecteplase Treatment in Acute Ischemic Stroke (TETRIS) Registry is multicenter ambispective observational study of patients with acute ischemic stroke who received intravenous thrombolysis with Tenecteplase
- Trial name
- TETRIS (NCT05534360)
- Where
- France
- Volunteers
- 5,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Acute Ischemic Stroke
Clinical Comprehensive Evaluation of Neuroprotective Drugs for Acute Ischemic Stroke
This study conducted a comprehensive evaluation of commonly used neuroprotective agents in acute ischemic stroke, assessing their real-world value across six dimensions: safety, efficacy, cost-effectiveness, innovativeness…
- Trial name
- Ischemic strok (NCT07260760)
- Volunteers
- 600 people
- Sponsor
- Qianfoshan Hospital
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