Clinical trials: stroke
Intracerebral Hemorrhage
Multinational Survey of Epidemiology, Morbidity, and Outcomes in Intracerebral Hemorrhage
The aim of this project is development of a comprehensive, prospective, multinational, multicenter, hospital-based, data repository for patients with intracerebral hemorrhage.
- Trial name
- MNEMONICH (NCT02567162)
- Volunteers
- 40 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Stroke, Brain Injuries
Investigating Usability of c-SIGHT in the Homes of Brain Injury Survivors
A brain injury can damage the brain, so that it no longer receives information about the space around one side of the world. If this happens, people may not be aware of anything on one side, usually the same side they also lost…
- Conditions
- Stroke, Brain Injuries, Spatial Neglect, Attention Deficit
- Trial name
- c-SIGHT (NCT03963661)
- Testing
- c-SIGHT (computorized spatial innatention grasping home-based therapy)
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- University of East Anglia
Post-stroke Depression
Transcranial Direct Current Stimulation on Post Stroke Depression
The aim of the research is to address the critical gap that limited number of RCTs are conducted on this topic. To further explore the efficacy of tDCs, large sample sizes, large follow up period and rigorously controlled…
- Trial name
- NCT06598670
- Testing
- tDCS, Conventional treatment
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Riphah International University
Stroke
Psychosocial/Behavioral Intervention in Post-Stroke Depression
The primary aim of this study is to determine the effect of a nurse-delivered psychosocial/behavioral intervention on reduction of depression in community dwelling post-stroke patients.
- Trial name
- NCT00194454
- Testing
- Modified cognitive behavioral therapy plus problem-solving, usual care
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- University of Washington
Spasticity
Adult Subjects Suffering From Lower Limb Spasticity Following Stroke
The purpose of the protocol is to assess the responder rate as defined by the achievement of the primary goal from the Goal Attainment Scale following one botulinum toxin type-A (BoNT-A) injection cycle in accordance with routine…
- Trial name
- VALGAS (NCT01444794)
- Where
- 24 sites in Spain
- Volunteers
- 100 people
- Sponsor
- Ipsen
Stroke, Cerebral Palsy
Design of an Affordable Gym for Post Stroke Rehabilitation
Rehab in a Crate is a therapy gym designed to be affordable, compact and easily transportable. The purpose of this particular study is to gain feedback on the initial design of the Rehab in a Crate system.
- Conditions
- Stroke, Cerebral Palsy, Healthy
- Trial name
- RehabCares (NCT02820480)
- Testing
- Rehab in a Crate System
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Ischemic Stroke, Hemorrhagic Stroke
Goal Attainment Scaling in Upper Limb Spasticity Treatment
Patients after stroke with upper limb spasticity treated with botulinum toxin-A (BTX-A) will be included in this two-part study.
- Trial name
- GASBTX (NCT04975646)
- Testing
- Prescribed exercise program
- Where
- Slovenia
- Volunteers
- 70 people
- Sponsor
- University Rehabilitation Institute, Republic of Slovenia
Intracerebral Hemorrhage, Atrial Fibrillation
Anticoagulation in ICH Survivors for Stroke Prevention and Recovery
Primary Aim: To determine if apixaban is superior to aspirin for prevention of the composite outcome of any stroke (hemorrhagic or ischemic) or death from any cause in patients with recent ICH and atrial fibrillation (AF).
- Trial name
- ASPIRE (NCT03907046)
- Testing
- Apixaban, Aspirin
- Where
- 187 sites in United States
- Volunteers
- 700 people
- Sponsor
- Yale University
Stroke (Subacute)
Effect of Immersive Virtual Reality Cognitive Rehabilitation on Subacute Stroke Patients (A Pilot Study)
This pilot randomized controlled trial aims to evaluate the effectiveness of cognitive rehabilitation using an immersive Virtual Reality (VR) system compared to conventional paper-and-pencil cognitive training in subacute stroke…
- Trial name
- NCT07506486
- Testing
- Immersive Virtual Reality System, Conventional Paper-and-Pencil Cognitive Training
- Where
- Indonesia
- Volunteers
- 22 people
- Sponsor
- Universitas Padjadjaran
Fluid-attenuated Inversion Recovery Sequence Vascular Hyperintensity-diffusion-weighted Imaging Mismatch(FVH-DWI Mismatch), Image Evaluation
Screening of Endovascular Thrombectomy With MRI in Acute Ischemic Stroke
The goal of this observational study is to learn about the role of MRI evaluation based on FVH-DWI mismatch principle in preoperative evaluation of endovascular thrombolectomy.
- Conditions
- Fluid-attenuated Inversion Recovery Sequence Vascular Hyperintensity-diffusion-weighted Imaging Mismatch(FVH-DWI Mismatch), Image Evaluation, Endovascular Thrombectomy
- Trial name
- NCT06213870
- Testing
- Surgical criteria
- Where
- China
- Volunteers
- 309 people
- Sponsor
- Tianjin Huanhu Hospital
Stroke, Vascular Dementia
Aricept to Improve Functional Tasks in Vascular Dementia
Medications for memory improvement are available but they may not actually improve the ability to do real world tasks. The purpose of this research study is to determine if a medicine used to treat memory problems…
- Conditions
- Stroke, Vascular Dementia, Memory Deficits
- Trial name
- NCT00457769
- Testing
- Donepezil and self-generated memory training, Donepezil and experimenter-administered memory training
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Kessler Foundation
Brain Diseases, Cardiovascular Diseases
pRESET for Occlusive Stroke Treatment
Compare the safety and effectiveness of pRESET to Solitaire in the treatment of stroke related to large vessel occlusion
- Conditions
- Brain Diseases, Cardiovascular Diseases, Central Nervous System Diseases, Cerebrovascular Disorders
- Trial name
- PROST (NCT03994822)
- Testing
- Mechanical Thrombectomy using the pRESET Thrombectomy device, Mechanical Thrombectomy using the Solitaire Revascularization Device
- Where
- 24 sites in United States, Germany
- Volunteers
- 340 people
- Sponsor
- phenox Inc.
Stroke
Reliability and Validity Study for SWE of Shoulder Muscles in Persons After Stroke.
This study aims 1. To examine the reliability of SWE assessment in the shoulder muscles of persons after a stroke. 2. To assess if differentiation can be made between the hemiplegic (HP) and non-hemiplegic (NHP) side and between…
- Trial name
- SWE_stroke (NCT04581551)
- Testing
- SWE assessor 1, SWE assessor 2, Stretch intervention
- Where
- 2 sites in Belgium
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Coronary Disease, Cardiovascular Diseases
Molecular Epidemiology of Myocardial Infarction and Stroke in Older Adults - Ancillary to CHS
To investigation the association of thrombosis and inflammation genes with sub-clinical cardiovascular disease and with incident myocardial infarction and stroke in older adults.
- Conditions
- Coronary Disease, Cardiovascular Diseases, Heart Diseases, Cerebrovascular Accident
- Trial name
- NCT00078429
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Seizures
Pilot Study of Bumetanide for Newborn Seizures
The main goal of the study is to obtain pharmacokinetic and safety data of bumetanide in newborns with refractory seizures. The overall hypothesis is that bumetanide, added to conventional antiepileptic (antiseizure) medications…
- Trial name
- NCT00830531
- Testing
- Bumetanide
- Where
- 4 sites in United States
- Volunteers
- 43 people
- Sponsor
- Soul, Janet , M.D.
Heat Stroke
Early Body Temperature Targets and Relationship With Prognosis in Patients With Heat Stroke
The goal of this observational study is to explore the optimal target body temperature in first 24 hours and the relationship between body temperature and adverse outcomes of heat stroke.
- Trial name
- NCT05921682
- Testing
- observation
- Where
- 6 sites in China
- Volunteers
- 100 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Cerebral Infarction, Clopidogrel,Poor Metabolism of (Disorder)
The Dynamic Effect of Non-cytochrome P450 Isoenzyme 3A4(CYP3A4)-Metabolized and Cytochrome P450 Isoenzyme 3A4(CYP3A4)-Metabolized Statins on Clopidogrel Resistance in Patients With Cerebral Infarction
The investigators team had found that the presence of dynamic changes of Clopidogrel resistance are not associated with genetic factors.
- Trial name
- NCT02411903
- Testing
- atorvastatin and clopidogrel, rosuvastatin and clopidogrel
- Volunteers
- 160 people
- Sponsor
- The Third Affiliated Hospital of Guangzhou Medical University
CVA (Cerebrovascular Accident)
A Novel, Comprehensive Approach to Post-stroke Gait Rehabilitation
The goal of this project is to determine the feasibility and optimal parameters of a novel, comprehensive approach to gait training in individuals with chronic stroke.
- Trial name
- NCT04411303
- Testing
- Step length biofeedback, Propulsive force biofeedback, Interlimb asymmetry biofeedback
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Southern California
Stroke, Cerebral Vascular Accident (CVA)/Stroke
Error-enhanced Learning & Recovery in 2 & 3 Dimensions
This study is being done to see how errors lead to improvement. Specifically, we are evaluating the errors stroke participants make during an upper extremity exercise program when reaching for a target using their affected arm.
- Trial name
- NCT05180786
- Testing
- Error Fields, No Error Fields
- Where
- 3 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Strokes Thrombotic
Comparison Between the Efficacy of CIMT and NDT Along With Conventional Physiotherapy Treatment on Upper Extremity Rehabilitation Among Patients of Stroke
To compare the efficacy of CIMT and NDT among stroke patients To study the phenomena of transfer of training To study relationship between the MMSE score and stroke rehabilitation
- Trial name
- CIMT (NCT06485583)
- Testing
- Constraint-induced movement therapy, Neurodevelopmental Treatment
- Where
- Pakistan
- Volunteers
- 10 people
- Sponsor
- Shalamar Institute of Health Sciences
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