Clinical trials: tACS
Transcranial Alternating Current Stimulation, Anxiety Disorder
Intervention Effect of Transcranial Alternating Current Stimulation(tACS) on Anxiety Disorder
To investigate the intervention effect of transcranial alternating current stimulation(tACS) on anxiety symptoms and somatic symptoms in patients with anxiety disorder and its underlying neural mechanism by MRI.
- Conditions
- Transcranial Alternating Current Stimulation, Anxiety Disorder, Magnetic Resonance Imaging
- Trial name
- NCT06026826
- Testing
- transcranial alternating current stimulation
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Anhui Medical University
Schizophrenia
The Hi-tACS on Cognitive Function in Patients With Schizophrenia
This study is a double-blind, randomized, controlled intervention study aimed at exploring whether high-frequency transcranial alternating current stimulation (Hi-tACS) can improve cognitive impairment in patients with…
- Trial name
- NCT06470516
- Testing
- high-frequency transcranial alternating current stimulation
- Where
- 2 sites in China
- Volunteers
- 100 people
- Sponsor
- Sir Run Run Shaw Hospital
Transcranial Alternating Current Stimulation, Depressive Disorder
Intervention Effect of High Definition Transcranial Alternating Current Stimulation (HD-tACS) on Depressive Disorder
To investigate the intervention effect of high definition transcranial alternating current stimulation (HD-tACS) on suicidal ideation in patients with depressive disorder and its underlying neural mechanism by magnetic resonance…
- Trial name
- NCT05932706
- Testing
- High definition transcranial alternating current stimulation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Anhui Medical University
Dementia, Memory Loss
Non-invasive Brain Stimulation for Cognitive and Motor Dysfunction in Dementia
This project aims to examine the efficacy of remote, caregiver-led tES/brain stimulation intervention targeted to improve memory, mobility, and executive functioning among older adults with mild cognitive impairment or mild…
- Conditions
- Dementia, Memory Loss, Alzheimer Disease, Executive Dysfunction
- Trial name
- ACDCStim (NCT05661084)
- Testing
- Transcranial alternating current stimulation (tACS) (active); Transcranial direct current stimulation (tDCS) (active)
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- Hebrew SeniorLife
Transcranial Alternating Current Stimulation, Post-stroke Aphasia
High Definition Transcranial Alternating Current Stimulation (HD-tACS) for Post-stroke Aphasia
To investigate the intervention effect of high definition transcranial alternating current stimulation(HD-tACS) in chronic post-stroke aphasia and its underlying neural mechanism by MRI.
- Conditions
- Transcranial Alternating Current Stimulation, Post-stroke Aphasia, Functional Magnetic Resonance Imaging
- Trial name
- NCT05502822
- Testing
- High definition transcranial alternating current stimulation
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Anhui Medical University
Mild Cognitive Impairment (MCI)
TACS to Engage Theta-Gamma Coupling and Enhance Working Memory in Patients With MCI (tACS-MCI)
This study is looking at a new non-invasive brain stimulation methods called transcranial alternating current stimulation (tACS) to see if it can improve working memory and thinking processes in people with Mild Cognitive…
- Trial name
- tACS-MCI (NCT06783283)
- Testing
- Transcranial Alternating Current Stimulation
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Centre for Addiction and Mental Health
Healthy
Effect of Transcranial Alternative Current Stimulation at Alpha Frequency (α-tACS) on Stressed Healthy Subjects
stress. Notably, several studies reported that stress could alter impulsivity, source monitoring, and time perception. Several mechanisms are involved in the response to a stress factor, among them the…
- Trial name
- CAF-TAS (NCT06229002)
- Testing
- Transcranial alternative current stimulation (tACS) at alpha frequency
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hôpital le Vinatier
Pain
Spatiotemporal Thalamocortical Alterations Underlie Experimental and Chronic Pain
The purpose of this study is to assess thalamocortical (TC) connectivity during tonic pressure pain, to evaluate alpha activity during tonic pressure pain and to determine pressure pain ratings by using Electroencephalography…
- Trial name
- NCT06968689
- Testing
- transcranial alternating current stimulation (tACS), transcranial random noise stimulation (tRNS)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Major Depressive Disorder, MDD
Transcranial Alternating Current Stimulation for Major Depressive Disorder
Investigating the effects of non-invasive transcranial alternating current stimulation (tACS) on patients with Major Depressive Disorder (MDD).
- Trial name
- MDD (NCT02339285)
- Testing
- tACS (alpha), tACS (gamma)
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of North Carolina, Chapel Hill
Visual Impairment, Stroke
Re-Orchestration of Interregional Oscillatory Activity to Promote Visual Recovery
This project assesses the effect of bifocal cross-frequency transcranial alternating current stimulation (tACS) combined with visual training to improve visual recovery and orchestrated oscillatory activity in stroke patients…
- Conditions
- Visual Impairment, Stroke, Parkinson Disease
- Trial name
- R4V (NCT05220449)
- Testing
- Cross-frequency dual-site tACS
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- Ecole Polytechnique Fédérale de Lausanne
Stroke
Transcranial Alternating Current Stimulation (tACS) to Improve Motor Skill Acquisition in Stroke Patients
Hand motor function is often severely affected in stroke patients and its recovery is one primary goal in stroke rehabilitative treatment programs.
- Trial name
- NCT05576129
- Testing
- TGP-tACS
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Transcranial Alternating Current Stimulation
Effects of Gamma-tACS on EEG Periodic Activity
In this study on healthy subjects, the effect of transcranial alternating current stimulation (tACS) will be investigated. In particular, the distinction between periodic and aperiodic electroencephalogram (EEG) activity will be…
- Trial name
- GAMMAtACS (NCT05809076)
- Testing
- real tACS
- Where
- Italy
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- IRCCS San Camillo, Venezia, Italy
Transcranial Alternating Current Stimulation, Frontotemporal Dementia (FTD)
Transcranial Alternating Current Stimulation in Frontotemporal Dementia
The aim of the study is to evaluate the safety, feasibility, clinical and biological efficacy, and predictors of efficacy of an intervention consisting of transcranial alternating current stimulation (tACS) in patients with…
- Trial name
- BetaTACSFTD (NCT07505784)
- Testing
- Transcranial Alternating Current Stimulation
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- IRCCS Centro San Giovanni di Dio Fatebenefratelli
Mild Cognitive Impairment, Healthy Aging
Novel, Individualized Brain Stimulation, Network-based Approaches to Improve Cognition
Impaired working memory (WM) plays a crucial role in normal aging, in mild cognitive impairment (MCI) and cognitive decline associated with dementia, such as Alzheimer's disease (AD).
- Trial name
- NiBS-iCog (NCT04986787)
- Testing
- tACS, TMS, TIS
- Where
- Czechia
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Masaryk University
Schizophrenia, Schizoaffective Disorder
STimulation to Improve Auditory haLLucinations
Investigating the effects of non-invasive transcranial current stimulation as a treatment for auditory hallucinations in patients with schizophrenia.
- Trial name
- STILL 2 (NCT02360228)
- Testing
- tACS (alpha), tDCS
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of North Carolina, Chapel Hill
Antenatal Depression
Single Session Personalized Aperiodic Transcranial Alternating Current Stimulation (PandA-tACS) for Antenatal Depression
The purpose of this pilot trial is to primarily assess safety, feasibility, and tolerability of PandA-tACS in antenatal depression and determine whether a single PandA-tACS session produces greater left dlPFC aperiodic slope…
- Trial name
- PandA (NCT07799480)
- Testing
- IAF-tACS, PandA-tACS
- Volunteers
- 60 people
- Sponsor
- University of North Carolina, Chapel Hill
Depression - Major Depressive Disorder, Transcranial Alternating Current Stimulation
Individualized Non-invasive Brain Stimulation for the Treatment of Major Depressive Disorder
The purpose of this research study is to study a closed-loop transcranial alternating current stimulation (tACS) device to evaluate feasibility of the product in a clinical trial and collect preliminary data on potential effects…
- Trial name
- CL-tACS RCT (NCT06874374)
- Testing
- Closed-loop tACS
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Pulvinar Neuro, LLC
Late-Life Depression, Anhedonia
Investigating the Efficacy and Mechanisms of Individualized tACS Targeting Anhedonia in Late-Life Depression
This project focuses on clinical translational research into personalized transcranial alternating current stimulation (tACS) for treating anhedonia in late-life depression (LLD).
- Trial name
- NCT07637773
- Testing
- Transcranial Alternating Current Stimulation (tACS)
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Jie Li
Tremor, Limb
The Trans-cutaneous Effects on Physiological Tremor Entertainment During tACS
Transcranial alternating current stimulation (tACS) is a noninvasive neuromodulation method that works by passing alternating electric current between electrodes where at least one of them is attached to the head.
- Trial name
- NCT04065022
- Testing
- tACS at tremor frequency
- Where
- Belgium
- Volunteers
- 22 people
- Sponsor
- KU Leuven
Cognitive Dysfunction, Mild Cognitive Impairment
Speed of Processing (SoP) Training Plus α-tACS
The current proposal aims to assess if the combination of Speed of Processing (SoP) training with alpha tACS (α-tACS) is able to increase brain speed of processing as assessed by the Useful Field of View (UFOV) when comparing to…
- Conditions
- Cognitive Dysfunction, Mild Cognitive Impairment, tACS, Cognitive Training
- Trial name
- aMCIUp (NCT05198726)
- Testing
- alpha tACS, Speed of Processing Training
- Where
- Portugal
- Volunteers
- 40 people
- Sponsor
- Portucalense University