Clinical trials: taVNS
Vagus Nerve Stimulation
Transcutaneous Auricular Vagus Nerve Stimulation Prevents Postoperative Delirium in Elderly Patients
According to the 3D-CAM scale, evaluate the incidence of Postoperative Delirium within 5 days after surgery in elderly patients receiving taVNS.The results are expected to provide evidence of the safety and efficacy of…
- Trial name
- Vnstar (NCT06421077)
- Testing
- transauricular auricular vagus nerve stimulation
- Where
- China
- Volunteers
- 1,776 people
- Sponsor
- Beijing Tiantan Hospital
Subarachnoid Hemorrhage, Aneurysmal, Delayed Cerebral Ischemia
Noninvasive CA Monitoring Validation and Autonomic Modulation in Aneurysmal Subarachnoid Hemorrhage
This is a two-component prospective study of adult aneurysmal subarachnoid hemorrhage (aSAH) patients admitted to the Neurosciences Intensive Care Unit (NSICU) at UT Southwestern Medical Center.
- Conditions
- Subarachnoid Hemorrhage, Aneurysmal, Delayed Cerebral Ischemia, Cerebral Vasospasm, Autonomic Nervous System Diseases
- Trial name
- NCT07577739
- Testing
- Right-Sided Cervical Sympathetic Block at C6, Transcutaneous Auricular Vagal Nerve Stimulation (taVNS)
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Texas Southwestern Medical Center
Upper Extremity Dysfunction, Stroke
taVNS Paired With Motor Training for Upper-extremity Rehabilitation in Stroke Patients
Background: Recently, there has been increasing attention on the application of transcutaneous auricular vagus nerve stimulation (taVNS) in ischemic stroke.
- Trial name
- NCT05943431
- Testing
- paired taVNS, Unpaired taVNS
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Qiuyou Xie
Desire; Sexual, Aversion, Paraphilia
Acute Intense Paraphilic Desire (DSM-V) Down-Regulation Via taVNS Neuro-Modulation [Transcutaneous Afferent Vagus Nerve] With Future Operative Implant Consideration
Transcutaneous Afferent Vagus Nerve Stimulation [taVNS] is used to modulate persistent \& intense desire control amongst a specific participant group. Testing Center Order of Deliver Number
- Trial name
- NCT05482412
- Testing
- transcutaneous (superficial) afferent electrical nerve stimulation specific for vagus nerve
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- American University Of Montserrat
Healthy, Psychedelic Experiences
The ENHANCE Study: taVNS and Psilocybin
This study will examine whether combining a single dose of psilocybin with non-invasive transcutaneous auricular vagus nerve stimulation (taVNS), a potential inducer of neuroplasticity and enhanced memory formation, will enhance…
- Conditions
- Healthy, Psychedelic Experiences, Vagus Nerve Stimulation
- Trial name
- ENHANCE (NCT05866471)
- Testing
- Psilocybin, Transcutaneous auricular Vagus Nerve Stimulation (taVNS), Psychosocial Support Alone
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Idiopathic Nephrotic Syndrome, Frequently Relapsing Nephrotic Syndrome
Effect of Daily Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) on Proteinuria in Pediatric Patients With Idiopathic Nephrotic Syndrome
This study evaluates the impact of transcutaneous auricular Vagus Nerve stimulation (taVNS) therapy on the incidence of nephrotic syndrome relapses in children with idiopathic nephrotic syndrome.
- Trial name
- taVNS (NCT04169776)
- Testing
- Transcutaneous Auricular Vagus Nerve (taVNS) stimulation
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Northwell Health
Psychological Distress, Stress (Psychology)
tAVNS for Stress Reduction in University Students
The goal of this clinical trial is to learn if transcutaneous auricular vagus nerve stimulation (taVNS) works to reduce perceived stress and psychological distress in university students with high distress levels.
- Conditions
- Psychological Distress, Stress (Psychology), Perceived Stress
- Trial name
- tAVNS4HES (NCT07411846)
- Testing
- taVNS
- Where
- Portugal
- Volunteers
- 40 people
- Sponsor
- Egas Moniz - Cooperativa de Ensino Superior, CRL
Healthy Adult Participants
The Effect of taVNS and Upper GI Motility
This single-center randomized controlled cross-over trial aims to investigate the effect of transcutaneous auricular vagus nerve stimulation on upper gastrointestinal motility in healthy individuals.
- Trial name
- NCT07632378
- Testing
- Vagal Nerve Stimulation
- Where
- Netherlands
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Daniel Keszthelyi
Dry Eye Disease
Transcutaneous Auricular Vagus Nerve Stimulation in Dry Eye Disease
Objective: To evaluate the effect of transcutaneous auricular vagus nerve stimulation (taVNS) for the patients with dry eye disease with meibomian gland dysfunction. Methods: We enrolled 256 patients at Beijing Tongren Hospital.
- Trial name
- NCT04673643
- Testing
- Transcutaneous Auricular Vagus Nerve Stimulation, Hyaluronic acid eye drops
- Where
- 2 sites in China
- Volunteers
- 128 people
- Sponsor
- Beijing Tongren Hospital
Pupillary Response
taVNS on Pupillary Response and Perceptual Learning
This study has two parts. The study team will evaluate transcutaneous auricular vagal nerve stimulation (taVNS) and two sham settings during a passive task while measuring pupillary response.
- Trial name
- NCT05386563
- Testing
- Transcutaneous Auricular Vagal Nerve Stimulation (taVNS)
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Nephrotic Syndrome in Children, Minimal Change Disease
taVNS for FRNS in Children
Children with frequently relapsing nephrotic syndrome (FRNS) are exposed to prolonged courses of steroids and other immunosuppressant medications.
- Conditions
- Nephrotic Syndrome in Children, Minimal Change Disease, Focal Segmental Glomerulosclerosis
- Trial name
- kidNEY-VNS (NCT05588063)
- Testing
- Transcutaneous auricular vagus nerve stimulation
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Northwell Health
Central Auditory Disease, Auditory Processing Disorder, Central
taVNS Effect on Central Auditory Processing
The behavioral effects of vagus nerve stimulation (VNS) and observed activation in the auditory cortex with transcutaneous auricular VNS (taVNS) raise questions about their potential impact on auditory processing.
- Conditions
- Central Auditory Disease, Auditory Processing Disorder, Central, Auditory Processing Disorders, Vagus Nerve Stimulation
- Trial name
- NCT06970444
- Testing
- transcutaneous auricular vagus nerve stimulation (taVNS)
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Medipol University
Stroke, Stroke, Ischemic
At-Home taVNS - Stroke Rehab
Early evidence suggests the benefits of post-stroke motor rehabilitation may be enhanced by applying electrical stimulation to the ear.
- Conditions
- Stroke, Stroke, Ischemic, Stroke Hemorrhagic
- Trial name
- NCT06616831
- Testing
- Remote Transcutaneous Auricular Vagal Nerve Stimulation Paired with Task-Specific Training
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Medical University of South Carolina
Fibromyalgia Syndrome
Unilateral and Bilateral taVNS in Fibromyalgia
This randomized controlled trial aimed to compare the effects of unilateral (left-sided) and bilateral transcutaneous auricular vagus nerve stimulation (taVNS) combined with a home exercise program on clinical outcomes, autonomic…
- Trial name
- taVNS-FMS (NCT07577102)
- Testing
- taVNS, Home Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Istanbul Gelisim University
Infertility Assisted Reproductive Technology
The Feasibility of taVNS on Pregnancy Outcomes of Infertility Patients Undergoing IVF
To assess the feasibility of taVNS on pregnancy outcomes of infertility subjects undergoing IVF, the primary aim of this trial will focus on encompassing recruitment, compliance, and preliminary engagement outcomes.
- Trial name
- NCT06742788
- Testing
- Transcutaneous Auricular Vagus Nerve Stimulation (taVNS)
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Xijing Hospital
Stroke Treatment, Stroke
Effect of Transcutaneous Auricular Vagus Nerve Stimulation Combined With Upper Extremity Robot-Assisted Training on Upper Extremity Motor Functions in Stroke Patients
The effects of stroke on the upper extremity are a common and significant cause of long-term disability, with 65% of patients reporting an inability to participate in daily activities with the affected upper extremity after 6…
- Trial name
- NCT07257107
- Testing
- Robotics Assisted Education + taVNS
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Istanbul University - Cerrahpasa
Post-COVID-19 Syndrome
Transcutaneous Vagus Nerve Stimulation (tVNS) for Improved Recovery After Exertion.
Widespread infection with SARS-CoV-2 has resulted in millions of people having Post-COVID. Post-COVID is a complex, non-monolithic disease with diverse clinical manifestations.
- Trial name
- NCT06510985
- Testing
- transcutaneous vagus nerve stimulation, Monitoring, cardiowatch bracelet
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- University Hospital Tuebingen
PARKINSON DISEASE (Disorder)
Using taVNS to Modulate Cardiovascular Function in Individuals With Neurologic Disease
The purpose of this study is to find out whether a type of gentle nerve stimulation, called transcutaneous auricular Vagus Nerve Stimulation (taVNS), can help improve how the body regulates heart rate and blood pressure in people…
- Trial name
- NCT07557706
- Testing
- transcutaneous auricular vagus nerve stimulation
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Alabama at Birmingham
Infant Development, Hemiplegia
CIMT and taVNS for Hemiplegia in Infants
Newborns who are born premature or suffer brain injury at birth are at risk for motor problems that may cause weakness in reaching and grasping on one side of the body.
- Conditions
- Infant Development, Hemiplegia, Constraint Induced Movement Therapy
- Trial name
- NCT05101707
- Testing
- transcutaneous auricular vagus nerve stimulation, Constraint induced movement therapy
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Medical University of South Carolina
Primary Dysmenorrhea (PD), Primary Dysmenorrhea
Effect of Auricular Vagus Nerve Stimulation on Pain and Symptoms in Primary Dysmenorrhea
This study aims to investigate the effects of transcutaneous auricular vagus nerve stimulation (taVNS) on menstrual pain, pain threshold, depression, anxiety, menstrual symptoms, premenstrual syndrome, and functional and…
- Trial name
- NCT07683637
- Testing
- Transcutaneous Auricular Vagus Nerve Stimulation (taVNS)
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul Gelisim University