Clinical trials: the Severity of Injuries
Core Temperature, Heat Stress, Exertional
Initial Stay Times and Heat Mitigation Controls for Uncompensable Occupational Heat Stress - Part II
Workplaces rely on upper heat stress limits provided by the American Conference of Governmental Industrial Hygienists (ACGIH) to manage the health and safety of workers in hot environments.
- Conditions
- Core Temperature, Heat Stress, Exertional, Heat Fatigue, Exercise
- Trial name
- NCT06543719
- Testing
- Simulated work in the heat
- Where
- Canada
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Hand Injuries and Disorders
Cross-cultural Adaptation and Validation of the CISS and the PWES Questionnaire in Patients With Hand Pathologies.
The primary objective of the study is to do translation, cross-cultural adaptation and validation of the CISS and PWES questionnaire in French. No available translation exist in French.
- Trial name
- NCT04646343
- Testing
- administration of F-CISS and F-PWES pre version, administration of definitive version of F-CISS and F-PWES plus F-DASH, F-HFS and F-SF 36
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- Clinique Romande de Readaptation
Head and Neck Cancer, Oral Complications of Radiation Therapy
Radiation Therapy With or Without Chemotherapy in Reducing Mouth Dryness in Patients With Nasopharyngeal Cancer
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Giving radiation therapy in different ways may cause less damage to normal tissue, prevent or lessen mouth dryness, and may help patients live more…
- Conditions
- Head and Neck Cancer, Oral Complications of Radiation Therapy, Radiation Toxicity
- Trial name
- NCT00057785
- Testing
- cisplatin, fluorouracil, Intensity modulated radiation therapy
- Where
- 17 sites in United States
- Volunteers
- 68 people
- Sponsor
- Radiation Therapy Oncology Group
Acute Respiratory Distress Syndrome, Acute Lung Injury
Effects of PEEP and FIO2 in ALI and ARDS
Current American-European Consensus Conference (AECC) definitions for ALI and ARDS are inadequate for inclusion into clinical trials due to the lack of standardization for measuring the oxygenation defect.
- Conditions
- Acute Respiratory Distress Syndrome, Acute Lung Injury, Acute Respiratory Failure
- Trial name
- HELP (NCT00435110)
- Testing
- standard ventilatory settings, PEEP and FiO2
- Where
- Spain
- Volunteers
- 178 people
- Sponsor
- Instituto Canario de Investigacion Biomedica
Spinal Cord Injury
Examination of the Role of Human Exoskeletons in Rehabilitation
Background and Rationale: Traumatic spinal cord injury (SCI) affects approximately 12,400 individuals annually in the USA, predominantly impacting healthy young adults aged 20-40 years.
- Trial name
- REHA-EXO (NCT07669181)
- Testing
- Exoskeleton based gait therapy
- Where
- Hungary
- Volunteers
- 50 people
- Sponsor
- University of Pecs
Shoulder Impingement Syndrome, Subacromial Impingement
The Effect of Mobilization With Movement in Individuals With Shoulder Impingement Syndrome
This study conducted to see the effect of adding mobilization with movement to conventional physical therapy to the subject with shoulder impingement syndrome.
- Conditions
- Shoulder Impingement Syndrome, Subacromial Impingement, Subacromial Impingement Syndrome, Subacromial Pain Syndrome
- Trial name
- SIS (NCT04599127)
- Testing
- Mobilization with movement, Conventional physical therapy
- Where
- Indonesia
- Volunteers
- 22 people
- Sponsor
- Mahidol University
COVID-19, Kidney Injury
Kidney Injury Severity and COVID-19
The authors hypothesize that the SARS-CoV-2 virus can affect the kidneys, causing them to be damaged. The present study aims to explain the mechanisms of kidney injury in patients diagnosed with COVID-19.
- Trial name
- NCT04386564
- Testing
- mRNA in urine test
- Where
- Russia
- Volunteers
- 340 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Optimal Intensity of Renal Replacement Therapy on Sepsis Patients
Effect of the Intensity of Continuous Renal Replacement Therapy
In patients with sepsis and AKI, increasing the intensity of renal replacement therapy from 50 mL/kg/h (HVHF) to 85 mL/kg/h (EHVHF)will increase the survival at 28 days and 90 days.
- Trial name
- NCT01251081
- Testing
- extra high volume hemofiltration, high volume hemofiltration
- Where
- China
- Volunteers
- 280 people
- Sponsor
- Zhejiang University
Rib Fractures, Rib Trauma
Investigation of the Effect of Age and Injury Severity on Short-term Intra-hospital Outcomes After Surgical Stabilized Rib Fractures
The study aims to investigate the effect of surgical stabilisation of rib fractures (SSRF) on clinical outcomes measured during the hospital stay (mortality, days on a mechanical ventilator, intensive care unit and hospital…
- Conditions
- Rib Fractures, Rib Trauma, Rib Fracture Multiple, Thorax; Fracture
- Trial name
- NCT06464302
- Testing
- Surgical stabilisation of rib fractures (SSRF), Non-operative management of rib fractures
- Where
- Germany
- Volunteers
- 1,064 people
- Sponsor
- University Hospital Muenster
Dry Eye Syndrome
Piiloset Trehalose Emulsion Eye Drop Study in Moderate or Severe Dry Eye
The study evaluates the safety, ocular tolerability and efficacy of emulsion eye drops with sacha inchi seed oil, trehalose and hyaluronic acid in the treatment of moderate or severe dry eye in adult patients.
- Trial name
- NCT03569202
- Testing
- Piiloset Trehalose Emulsion Eye Drops, Control Eye Drops
- Where
- Finland
- Volunteers
- 64 people
- Sponsor
- Kuopio University Hospital
Ankle Sprain 1St Degree, Ankle Sprain 2Nd Degree
The Effect of Low-Intensity Blood Flow Restriction Therapy on the Management of Acute Ankle Sprains
The primary objective of this study is to evaluate the feasibility of implementing BFR in the rehabilitation treatment of isolated ankle sprains as well as to evaluate the clinical benefits of BFR when compared to standard…
- Conditions
- Ankle Sprain 1St Degree, Ankle Sprain 2Nd Degree, Musculoskeletal Injury
- Trial name
- NCT05596162
- Testing
- Blood Flow Restriction Therapy, Standard Physical Therapy
- Where
- United States
- Sponsor
- Vanderbilt University Medical Center
Shoulder Pain, Hemiplegia
High Intensity Laser Therapy in the Treatment of Hemiplegic Shoulder Pain
High intensity laser therapy (HILT) has been considered as a treatment option for shoulder pain. In randomized controlled studies with high-intensity laser therapy (HILT), there are publications showing its effectiveness in…
- Conditions
- Shoulder Pain, Hemiplegia, Arthralgia, Joint Diseases
- Trial name
- NCT05564182
- Testing
- High intensity laser therapy, Therapeutic Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Afyonkarahisar Health Sciences University
Thoracic Trauma, Blunt Trauma
The Predictive Value of Chest Trauma Score and Thoracic Trauma Severity Score in Thoracic Trauma Patients
The aim of this prospective study is Comparing the diagnostic accuracy of chest Trauma Score and Thoracic Trauma Severity Score in predicting morbidity and mortality.
- Trial name
- NCT07822191
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Body Temperature Changes, Heat Stress
Exercise Intensity and Heat Responses in Children and Youth
Little is known about how children and youth regulate body temperature during exercise in the heat compared with young adults, including whether differences in whole-body heat exchange contribute to their responses.
- Conditions
- Body Temperature Changes, Heat Stress, Child Development, Heat
- Trial name
- NCT07781592
- Testing
- Low-Intensity Exercise in the Heat, Moderate-Intensity Exercise in the Heat, Vigorous-Intensity Exercise in the Heat
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Radiodermatitis, Oncology
Jalosome® Soothing Gel Efficacy Grade 2 or 3 Radiodermatitis.
Testing the efficacy of the Jalosome® Soothing gel in 2 or 3 grade radiodermatitis healing in oncological patients. The investigators would like to know also the efficacy of the device on quality of life and pain.
- Conditions
- Radiodermatitis, Oncology, Quality of Life, Pain
- Trial name
- NCT04692389
- Testing
- Jalosome soothing gel
- Where
- Switzerland
- Sponsor
- Welcare Industries SpA
Injuries, Multiple, Norway/Epidemiology
Trauma Registration at St. Olavs Hospital 2000-2003
St. Olavs Hospital is a trauma referral center in the region of Midtnorge. Admitting trauma patients locally and those referred from hospitals in Nord-Trøndelag, Sør-Trøndelag and Møre-Romsdal.An active trauma team was defined in…
- Conditions
- Injuries, Multiple, Norway/Epidemiology, Trauma Centers/Statistics & Numerical Data, Trauma, Multiple
- Trial name
- NCT00184470
- Volunteers
- 1,000 people
- Sponsor
- Norwegian University of Science and Technology
Bone Metastases, Bone Neoplasm
Feasibility of Combined Focused Ultrasound and Radiotherapy Treatment in Patients With Painful Bone Metastasis
The PRE-FURTHER study aims to evaluate the feasibility of the combined treatment with radiotherapy and focussed ultrasound for pain palliation in patients with painful bone metastases, and to optimize the combined treatment…
- Conditions
- Bone Metastases, Bone Neoplasm, Bone Lesion, Bone Cancer
- Trial name
- PRE-FURTHER (NCT04310410)
- Testing
- combined radiotherapy and MR-HIFU
- Where
- 2 sites in Netherlands
- Volunteers
- 10 people
- Sponsor
- UMC Utrecht
Paroxysmal Sympathetic Hyperactivity
Effects of Early Musical Intervention on Prevalence and Severity of Paroxysmal Sympathetic Hyperactivity After Severe Traumatic Brain Injury
Paroxysmal sympathetic hyperactivity (PSH) is a frequent symptom after traumatic brain injury and concerns up to 30% of severely brain-injured patients.
- Trial name
- MUSIC-TCNV (NCT02783105)
- Testing
- Musical intervention, Control
- Where
- France
- Volunteers
- 11 people
- Sponsor
- University Hospital, Strasbourg, France
Traumatic Injuries, Prehospital Emergency Care
Study of Pre Hospital Management of Polytrauma Patients by Medical Teams From a Department in the Parisian Region
To study the impact of prehospital management duration by SMUR teams in the Essonne department (91) on early patient mortality (within 24 hours) and to analyze the procedures performed on scene.
- Conditions
- Traumatic Injuries, Prehospital Emergency Care, Early Mortality
- Trial name
- DELTA-91 (NCT07414186)
- Where
- France
- Volunteers
- 400 people
- Sponsor
- Centre Hospitalier Sud Francilien
Hypothermia
Study to Determine the Effects of Pre-warming on OR Patient Temperatures and Surgical Outcomes
The application of active warming to patients whether awake or under general anesthesia has been proven safe in numerous studies and it is common practice to use warmers.
- Trial name
- NCT02177903
- Testing
- Bair Paws Patient Adjustable Warming System
- Where
- Canada
- Volunteers
- 220 people
- Sponsor
- Solventum US LLC