Clinical trials: tuberculosis
Hepatitis, Tuberculosis
Anti-tuberculosis (TB) Drug Levels and Correlation With Drug Induced Hepatotoxicity
The purpose of the study is to estimate plasma drug levels ( free and total drug levels ) of rifampicin and other antituberculosis drugs and compare these drug levels in patients who develop drug induced hepatotoxicity versus…
- Trial name
- NCT01456845
- Where
- India
- Volunteers
- 110 people
- Sponsor
- All India Institute of Medical Sciences
Tuberculosis, Pulmonary, HIV Coinfection
Pharmacist-Led Intervention to Improve TB Treatment Adherence
The goal of this clinical trial is to compare the adherence of co-morbid patients in control and experimental group The main question[s]it aims to answer are: 1.
- Trial name
- RA-15041995 (NCT06608069)
- Testing
- Educational counselling
- Where
- 2 sites in Malaysia
- Volunteers
- 383 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Pneumonia, Pulmonary Fibrosis
Pulmonary Rehabilitation in Non-chronic Obstructive Pulmonary Disease Patients.
To determine the effect of pulmonary rehabilitation on pulmonary function in non-chronic obstructive pulmonary disease patients.To determine the effect of pulmonary rehabilitation on health related quality of life in non-chronic…
- Conditions
- Pneumonia, Pulmonary Fibrosis, Tuberculosis, Bronchiectasis
- Trial name
- NCT05174741
- Testing
- Conventional Chest Physiotherapy, Aerobic training Group
- Where
- Pakistan
- Volunteers
- 20 people
- Sponsor
- Riphah International University
Pulmonary Tuberculosis
Phase 2 Trial to Evaluate the Early Bactericidal Activity, Safety and Tolerability of Meropenem Plus Amoxycillin/CA and Faropenem Plus Amoxycillin/CA in Adult Patients With Newly Diagnosed Pulmonary Tuberculosis
To evaluate the early bactericidal activity (EBA), safety, tolerability and pharmacokinetics of meropenem administered intravenously three times a day, plus amoxycillin/CA administered orally three times a day; and of faropenem…
- Trial name
- NCT02349841
- Testing
- Meropenem, Faropenem, Amoxycillin/clavulanic acid
- Where
- South Africa
- Volunteers
- 46 people
- Sponsor
- TASK Applied Science
Tuberculosis, Hiv
A Study of the Pharmacokinetic and Pharmacodynamic Interactions Between Bictegravir, Tenofovir Alafenamide and Rifapentine in Healthy Adult Subjects
This is a single-center, open-label, fixed sequence, pharmacokinetic interaction study between bictegravir and tenofovir alafenamide with rifapentine dosed either daily or weekly.
- Trial name
- NCT04551573
- Testing
- Rifapentine daily, Rifapentine weekly
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Yale University
HIV Infections, Tuberculosis
Digital Health Promotion in Iringa, Tanzania
Increased health education has the potential to facilitate better use of health care services and to promote early treatment, thus it can strengthen the health care system, and ultimately reduce morbidity and mortality.
- Conditions
- HIV Infections, Tuberculosis, Cysticercosis, Tapeworm Pork
- Trial name
- NCT03808597
- Testing
- Digital health promotion intervention
- Where
- 6 sites in Tanzania
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Pulmonary TB
Risk Factors and Biomarkers for Post-tuberculosis Lung Damage
This prospective study aims to determine the incidence of Post-tuberculosis lung damage (PTLD), examine trends in the changes in lung function, and investigate the impact of smoking and other factors on respiratory symptoms, lung…
- Trial name
- NCT05426720
- Testing
- no intervention
- Where
- 2 sites in China
- Volunteers
- 400 people
- Sponsor
- Peking University Third Hospital
HIV Seropositivity, Tuberculosis
Comparing Treatment Completion Of Daily Rifapentine & Isoniazid For One Month (1HP) To Weekly High Dose Rifapentine & Isoniazid For 3 Months (3HP) In Persons Living With HIV and in Household Contacts of Recently Diagnosed Tuberculosis Patients
A multicenter, randomized, stratified, open-label, phase IV trial among HIV-positive persons (PLHIV) on antiretroviral therapy (ART), or HIV-negative household contacts of patients with rifampicin-sensitive pulmonary tuberculosis…
- Conditions
- HIV Seropositivity, Tuberculosis, Household Contact
- Trial name
- 1 to 3 (NCT05118490)
- Testing
- Daily rifapentine and isoniazid for 4 weeks, Weekly rifapentine and isoniazid for 12 weeks
- Where
- 4 sites in India, Indonesia and 2 more
- Volunteers
- 1,000 people
- Sponsor
- The Aurum Institute NPC
Malnutrition, Child, Tuberculosis
The Impact of Malnutrition on Immune Responses to Tuberculosis
The aim of this study is to assess immune responses to Mtb in children with MAM compared to well-nourished children and to evaluate the impact of a nutrition intervention on these immune responses.
- Trial name
- TBMAM (NCT05044910)
- Testing
- Ready to Use supplementary food (RUSF)
- Where
- 2 sites in India
- Volunteers
- 200 people
- Sponsor
- Tuberculosis Research Centre, India
Tuberculosis
Pharmacokinetic Interaction Study in Indonesian Tuberculosis Patients Indonesia
Pharmacokinetic study in TB patients to determine the effect of rifampicin on the pharmacokinetic profile of moxifloxacin.
- Trial name
- NCT00306319
- Testing
- moxifloxacin
- Where
- Indonesia
- Volunteers
- 23 people
- Sponsor
- Radboud University Medical Center
Tuberculosis, Pulmonary
Digital Health Intervention to Improve TPT Uptake
Despite the evidence of the prevention and control measures of tuberculosis (TB), it still has an impact on the health, social, and economic aspects of the population.
- Trial name
- DHiTPT (NCT07313995)
- Testing
- Digital health intervention
- Where
- 14 sites in Ethiopia
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- Arba Minch University
Latent Tuberculosis Infection, Tuberculosis Infection, Latent
Evaluation of a Novel Microbiological Diagnostic Test for Latent Mycobacterium Tuberculosis Infection
Tuberculosis (TB) is an infectious disease that is caused by bacteria (bugs). The infection is passed on when a patient with active lung TB coughs bugs into the air, which are then breathed in by an uninfected person.
- Trial name
- MICRO-LTBI (NCT06728930)
- Where
- United Kingdom
- Volunteers
- 250 people
- Sponsor
- Queen Mary University of London
HIV, Tuberculosis
Tuberculosis and Human Immunodeficiency Virus (HIV) Immune Reconstitution Syndrome Trial (THIRST)
The purpose of this study is twofold: (1) to assess the feasibility and safety of fixed dose combination zidovudine/lamivudine/abacavir in HIV infected subjects with tuberculosis in a resource-limited setting, and (2) to assess…
- Trial name
- THIRST (NCT00851630)
- Testing
- Fixed dose combination zidovudine/lamivudine/abacavir
- Where
- Tanzania
- Volunteers
- 70 people
- Sponsor
- Duke University
Tuberculosis
Pharmacokinetics and Safety of Moxifloxacin
The main objective of this prospective clinical trial is to compare pharmacokinetics and safety and tolerability of a standard dose (400 mg) with an escalated dose (600 mg; 800 mg) of moxifloxacin (MFX).
- Trial name
- MFX468 (NCT01329250)
- Testing
- Moxifloxacin
- Where
- Netherlands
- Volunteers
- 9 people
- Sponsor
- University Medical Center Groningen
Extrapulmonary Tuberculosis in HIV Patients
PET/CT in Extrapulmonary TB in HIV Patients: a Clinical Trial
Objective Prospectively describe the kinetics of 18F-FDG uptake of extrapulmonary TB after two months and at the end of TB treatment in HIV patients. Evaluate 18F-FDG-PET/CT as a TB treatment response monitoring tool.
- Trial name
- NCT02822014
- Testing
- FDG-PET/CT
- Volunteers
- 18 people
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Tuberculosis, Pediatric
TB Innovation Project: A Pre- and Post- Implementation Assessment (TIPPI)
This evaluation will be conducted in ten countries involved in the Catalyzing Pediatric TB Innovation (CaP-TB) project: Cameroon, Cote D'Ivoire, Democratic Republic of Congo, Kenya, Lesotho, Malawi, Tanzania, Uganda, Zimbabwe and…
- Trial name
- TIPPI (NCT03948698)
- Testing
- Innovative approached to pediatric TB care
- Where
- 10 sites in Cameroon, Côte d’Ivoire and 8 more
- Volunteers
- 4,159,533 people
- Sponsor
- Elizabeth Glaser Pediatric AIDS Foundation
Tuberculosis, HIV Infections
Tuberculosis in HIV Infected Patients in Uganda
This was a clinical trial in HIV infected patients with tuberculosis. The study assessed whether the addition of prednisolone, a type of steroid medication, to the standard treatment for tuberculosis improved immune and viral…
- Trial name
- NCT00057421
- Testing
- prednisolone
- Where
- Uganda
- Volunteers
- 190 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Tuberculosis (TB), Tuberculosis Vaccines
Immunogenicity and Safety of a Candidate Tuberculosis (TB) Vaccine Given to Healthy Adults in a TB-endemic Region
This study will assess the safety and immunogenicity of a GSK Biologicals' candidate TB vaccine administered at 0, 1 months to healthy adults living in a TB-endemic region.
- Trial name
- NCT00600782
- Testing
- GSK Biologicals' Candidate Tuberculosis (TB) Vaccine (692342)
- Where
- South Africa
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Tuberculosis, Pulmonary, Tuberculosis, Multidrug-Resistant
Trial to Evaluate the Efficacy, Safety and Tolerability of BPaMZ in Drug-Sensitive (DS-TB) Adult Patients and Drug-Resistant (DR-TB) Adult Patients
To evaluate the efficacy, safety and tolerability at 8 weeks (2-months), 52 weeks (12-months), and 104 Weeks (24-months) post the start of the following treatment regimens in participants with: Drug Sensitive TB (DS-TB) patients…
- Conditions
- Tuberculosis, Pulmonary, Tuberculosis, Multidrug-Resistant, Tuberculosis, MDR, Tuberculosis
- Trial name
- NCT03338621
- Testing
- Pretomanid, Bedaquiline, Moxifloxacin
- Where
- 26 sites in Brazil, Georgia and 6 more
- Volunteers
- 455 people
- Sponsor
- Global Alliance for TB Drug Development
HIV, Tuberculosis
Vicente Ferrer HIV Cohort Study
The VFHCS is a long-term prospective cohort study of HIV infected patients from a resource-poor rural setting in India. The aim of the study is to use data collected from routine clinical care in order to describe the…
- Conditions
- HIV, Tuberculosis, Cryptococcosis, Opportunistic Infections
- Trial name
- VFHCS (NCT02454569)
- Where
- India
- Volunteers
- 30,000 people
- Sponsor
- Rural Development Trust Hospital
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.