Clinical trials: in Albania
Inborn Errors of Metabolism, Biomarker
Biomarkers for Inborn Errors of Metabolism
International, multicenter, observational, longitudinal study to identify or monitor Inborn Error of Metabolism disease biomarkers and to explore the clinical robustness, specificity, and long-term variability of these biomarkers
- Trial name
- BioMetabol (NCT04098198)
- Where
- 13 sites in Albania, Egypt and 6 more
- Volunteers
- 462 people
- Sponsor
- CENTOGENE GmbH Rostock
Post Traumatic Stress Disorder, Depression
Impact of COVID-19 Pandemic in Perinatal Mental Health (RISEUP-PPD-COVID-19)
Introduction: Coronavirus disease 2019 (COVID-19) is a new pathology, declared a public health emergency by the World Health Organization, which can have negative consequences for pregnant women and their newborns.
- Conditions
- Post Traumatic Stress Disorder, Depression, Anxiety, Psychological Distress
- Trial name
- NCT04595123
- Where
- 13 sites in Albania, Brazil and 11 more
- Volunteers
- 7,642 people, healthy volunteers welcome
- Sponsor
- University of Minho
Beta Thalassemia Major
Phase 2a Pilot Study of NBMI Treatment in Patients With Beta Thalassemia Major, Requiring Iron Chelation
A pilot study to explore safety and efficacy of NBMI treatment in patients with Beta Thalassemia Major requiring iron chelation Investigational product: NBMI (N1,N3-bis(2-mercaptoethyl) isophthalamide), INN: Emeramide Indication…
- Trial name
- EMERA007 (NCT04092205)
- Testing
- Emeramide
- Where
- Albania
- Volunteers
- 13 people
- Sponsor
- EmeraMed
Lysosomal Storage Diseases, Gaucher Disease
Lyso-Gb1 as a Long-term Prognostic Biomarker in Gaucher Disease
International, multicenter, epidemiological study to demonstrate the correlation and predictive value of lyso-Gb1 concentration with the clinical severity of naïve, initially non-ERT/SRT Gaucher disease type 1 and during the…
- Conditions
- Lysosomal Storage Diseases, Gaucher Disease, Sphingolipidoses
- Trial name
- LYSO-PROOF (NCT02416661)
- Where
- 8 sites in Albania, Greece and 5 more
- Volunteers
- 299 people
- Sponsor
- CENTOGENE GmbH Rostock
Chronic Iron Overload
Efficacy/Safety Study of Deferiprone Compared to Deferasirox in Paediatric Patients
Multicentre, randomised, open label, non-inferiority active-controlled trial to evaluate efficacy and safety of a 12-months treatment with deferiprone (DFP) at dose of 75-100 mg/kg/day versus deferasirox (DFX) at dose of 20-40…
- Trial name
- NCT01825512
- Testing
- Deferiprone, Deferasirox
- Where
- 22 sites in Albania, Cyprus and 5 more
- Volunteers
- 435 people
- Sponsor
- Consorzio per Valutazioni Biologiche e Farmacologiche
Breast Neoplasms
A Safety and Tolerability Study of Assisted and Self-Administered Subcutaneous (SC) Herceptin (Trastuzumab) as Adjuvant Therapy in Early Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Breast Cancer
This multicenter, two-cohort, non-randomized, open-label study will evaluate the safety and tolerability of assisted and self-administered SC Herceptin as adjuvant therapy in participants with early HER2-positive breast cancer…
- Trial name
- SafeHER (NCT01566721)
- Testing
- Herceptin
- Where
- 437 sites in Albania, Algeria and 57 more
- Volunteers
- 2,577 people
- Sponsor
- Hoffmann-La Roche
Covid19
COVID-19 Vaccine Effectiveness in Albanian Health Workers
The purpose of this study is to evaluate the effectiveness of the COVID-19 vaccine in hospital based HWs in Albania. This will answer critical questions about the real-world performance of COVID-19 vaccines in one of the key…
- Trial name
- COVEAL (NCT04811391)
- Testing
- COVID-19 vaccine
- Where
- 3 sites in Albania
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Institute of Public Health, Albania
Tailored Implementation: Online ItFits-toolkit, Implementation as Usual
ImpleMentAll - Towards Evidence-based Tailored Implementation Strategies for eHealth
The ImpleMentAll (IMA) project aims to examine the effectiveness of tailored implementation compared to usual implementation of Internet-based Cognitive Behavioural Therapy (iCBT) for patients suffering from common mental…
- Trial name
- ImpleMentAll (NCT03652883)
- Testing
- ItFits-toolkit, Implementation as Usual
- Where
- 12 sites in Albania, Australia and 7 more
- Volunteers
- 456 people, healthy volunteers welcome
- Sponsor
- VU University of Amsterdam
Carbapenem Resistant Bacteria Infection
European Prospective Cohort Study on Enterobacteriaceae Showing Resistance to Carbapenems
Among antibiotic-resistant organisms, the Gram-negative bacteria are now the most important challenge because of the rapid worldwide spread of mechanisms conferring resistance to multiple drugs.
- Trial name
- EURECA (NCT02709408)
- Where
- 50 sites in Albania, Bulgaria and 9 more
- Volunteers
- 2,515 people
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Anxiety, Depression
Risk Factors for Anxiety and Depression Among Pregnant Women During the COVID-19 Pandemic
The article presents a protocol of a cross-sectional study of mental health of pregnant women in relation to the COVID 19 pandemic.
- Conditions
- Anxiety, Depression, Pregnancy Related
- Trial name
- MindCOVID (NCT04377412)
- Testing
- Pandemic control measures
- Where
- 17 sites in United States, Albania and 13 more
- Volunteers
- 8,500 people, healthy volunteers welcome
- Sponsor
- Żelazna Medical Centre, LLC
Glioblastoma, Glioma of Brain
An Expanded Access Program of Ipilimumab for Patients With Glioblastomas and Gliomas
IPILIMUMAB Extended Access Program for patients who received chemotherapy and / or radiation therapy before the protocol, before or after the operation.
- Trial name
- NCT03460782
- Testing
- Ipilimumab
- Where
- 11 sites in Albania, Bosnia and Herzegovina and 6 more
- Sponsor
- Center Trials & Treatment
Dental Implant Failed, Bone Resorption
SA Versus SOI Surfaces for Single Implant-supported Crown
The purpose of this randomized controlled trial is to compare clinical data and implant stability of immediately loaded TSIII Osstem implants with Sandblasted and Acid-etched (SA) surface versus implants with SA surface modified…
- Trial name
- NCT04073654
- Testing
- Placement of dental implants (surgical procedure)
- Where
- 10 sites in Albania, Bulgaria and 6 more
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Osstem AIC
Edentulous Alveolar Ridge, Bone Atrophy, Alveolar
Crestal vs Lateral Sinus Lift Augmentation
The aim of this randomised controlled trial (RCT) of split-mouth design was to compare patient preference and effectiveness of two different techniques for lifting the maxillary sinus: the crestal approach versus the lateral…
- Trial name
- NCT04111250
- Testing
- Maxillary sinus augmentation
- Where
- Albania
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Hospital San Pietro Fatebenefratelli
Non-Hodgkin's Lymphoma
A Study Comparing Maintenance Subcutaneous Rituximab With Observation Only in Participants With Relapsed or Refractory Indolent Non-Hodgkin's Lymphoma Who Had Responded to Rituximab-based Immunochemotherapy Induction and 2-year Maintenance With Subcutaneous Rituximab
This multicenter, randomized, open-label, parallel-group study will evaluate the efficacy and safety of subcutaneously administered rituximab in comparison with observation only as maintenance therapy in participants with…
- Trial name
- MabCute (NCT01461928)
- Testing
- Chemotherapy (Induction Period), Rituximab
- Where
- 180 sites in Albania, Argentina and 22 more
- Volunteers
- 692 people
- Sponsor
- Hoffmann-La Roche
Multiple Sclerosis
Noninterventional Study Assessing Cognitive Function and Physical Activity in People With Multiple Sclerosis
Study assessing cognitive function and physical activity in people with relapsing remitting multiple sclerosis.
- Trial name
- CogniPlus (NCT01491100)
- Testing
- Interferon beta-1b (Betaseron, BAY86-5046)
- Where
- 17 sites in Albania, Algeria and 15 more
- Volunteers
- 1,085 people
- Sponsor
- Bayer
Malignant Melanoma
A Study of Vemurafenib in Participants With Metastatic Melanoma
This multi-center study evaluates the safety and efficacy of vemurafenib in participants with BRAF V600 mutation-positive, surgically incurable, and unresectable Stage IIIC or IV (American Joint Committee on Cancer [AJCC])…
- Trial name
- NCT01307397
- Testing
- Vemurafenib
- Where
- 280 sites in Albania, Argentina and 42 more
- Volunteers
- 3,219 people
- Sponsor
- Hoffmann-La Roche
Non-Hodgkin's Lymphoma
MAXIMA Study: A Study of Maintenance Therapy With MabThera (Rituximab) in Patients With Non-Hodgkin's Lymphoma.
This single arm study will evaluate the safety and efficacy of MabThera maintenance therapy following a MabThera-containing induction regimen in first line or relapsed patients with follicular non-Hodgkin's lymphoma.
- Trial name
- NCT00430352
- Testing
- rituximab [MabThera/Rituxan]
- Where
- 178 sites in Albania, Argentina and 22 more
- Volunteers
- 545 people
- Sponsor
- Hoffmann-La Roche
Diabetes Mellitus, Type 2
Efficacy and Safety of Albiglutide in Treatment of Type 2 Diabetes
The purpose of this study is to determine if albiglutide is safe and effective in the treatment of type 2 diabetes.
- Trial name
- NCT00838903
- Testing
- albiglutide, sitagliptin, glimepiride
- Where
- 386 sites in United States, Albania and 9 more
- Volunteers
- 1,049 people
- Sponsor
- GlaxoSmithKline
Biomarkers
Role of Concentration of Biomarkers S100B and NSE in Serum in Mild and Moderate Head Trauma
In pediatric age groups communication difficulties very sometimes may present further obstacles in obtaining a detailed injury history and early identification of TBI symptoms.
- Trial name
- NCT02988102
- Testing
- Following S100B and NSE in head trauma
- Where
- Albania
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University Clinical Centre of Kosova
Anemia, Kidney Disease, Chronic
An Observational Study of Mircera (Methoxy Polyethylene Glycol-Epoetin Beta) in Patients With Chronic Kidney Disease in Pre-Dialysis or Dialysis
This prospective observational study will assess the efficacy and safety of Mircera (methoxy polyethylene glycol-epoetin beta) in clinical practice in patients with chronic kidney disease, in pre-dialysis or on dialysis…
- Trial name
- NCT01309295
- Where
- Albania
- Volunteers
- 250 people
- Sponsor
- Hoffmann-La Roche